FORMULATION AND EVALUATION OF CHAMOMILE VAGINAL SUPPOSITORIES

ABSTRACT :. It is to modify chamomile vaginal suppositories .used for vaginal infection, inflammatory problems ,lower
gastrointestinal tract.This article gives detail formulation and evaluation of chomamile vaginal suppositories
INTRODUCTION :. Suppositories - type of dosage form used to deliever medicament via rectal,vaginal channel
Vaginal suppositories- this are solid dosage form comes in varieties of weight and shape
PLANT PROFILE : Kingdom - Plantae
METHODOLOGY:
Botanical name - Matricaria chamomilla Extraction procedure:-
Order - Abterates
Synonym - Chamomilla L 1. Soxhlet apparatus
Genus - Matricaria
Family - Asterceae 2. Simple steam distillation

Simple steam distillation

BIBLIOGRAPHY:
1. Mohammed Ghazwani, Umme Hani,
M. Yasmin Begum An Efficient Herbal
Approach for Treating Fungal Infection
in Cervical Cancer Patients by
Developing and Optimizing a Vaginal
Soxhlet apparatus
Dried chamomile powder Suppository, International Journal of

FORMULATION :
Polymer Science , vol. 2021, Article ID
9198387, 11 pages, 2021.

EVALUATION PARAMETERS: 2. V.M. Chandrashekhar , K.S.

Chamomile suppositories preparation : Halagali, R.B. Nidavani,

Chemical parameters: Physical parameters

M.H.Shalavadi, B.S. Biradar,D. Biswas,
I.S. Muchchandi, Anti-allergic activity
Gelatin were soaked in water for 10 mins of German chamomile (Matricaria
1. Physiochemical recutita L.) in mast cell mediated
1.Weight variation allergy model, Journal of
2 weight variation Ethnopharmacology, may 2011.
2.Determination of pH
3.Determination of PH 3. Sanjeevani Shekhar
3.Measuremring of melting point Deshkar,JayashriG.Mahore,,Herb
4.Measurement of melting point
Glycerin was heated in water al bioactive–based vaginal and
rectal drug
5.Stability. deliverysystems,Herbal
bath at 65°C.chamomile was disperesed Bioactive-Based
DrugDeliverySystems,2022,Pages
after stirring 111-168,

4. Bayan Al‑Dabbagh, Ismail A.

Elhaty, Mohamed Elhaw,
Glycerin and chamomile was poured in gelatin Chandraprabha Murali, Ameera Al
Mansoori, Basma Awad and Amr
with stirring Amin, Antioxidant and anticancer
activities of chamomile (Matricaria

Then the final mixing was cooled at 40-45°c &

USES : Anti inflammatory Antibacterial activity
Antioxidant. Antimicrobial activity
recutita L.), BMC research notes.

Infection treating Antiallergic activity

poured into suppositories mould n refrigerated at 3-4°c Vaginal infection Bacterial vaginosis