CORTEZ, ALESSANDRA FRANCHESCA E.

BSN2-C

SPEEDA

SIDE EFFECTS
NAME AND
OF CLASSIFICATION MECHANISM OF CONTRAINDICATION INDICATION ADVERSE NURSING
DRUG ACTION EFFECTS RESPONSIBILITIES
Corticosteroids,  Following Hypersensitivity. Post- Active Pain, erythema, Nursing personnel
Speeda immunosuppressant immunizat exposure therapy, pre- immunization edema, should be warned
s. Rabies, ion, the exposure prophylaxis. against pruritus, against possible risk of
inactivated, vaccine rabies. induration at inj contamination.
J07BG01 - rabies, can site; moderate They should wear
inactivated, whole induce fever, shivering, masks, gloves, goggles
virus ; Belongs to immunity faintness, & aprons to protect
the class of rabies asthenia, themselves.
against
viral vaccines. headache, Nurses having bruises,
the rabies
dizzinesss, cuts or open wounds
virus in arthralgia, should not be entrusted
recipients, myalgia, GI to look after the patient.
and it is disorders eg, Pre- exposure
used to nausea, prophylaxis with 2-3
protect abdominal pain; doses of HDC vaccine
against anaphylactiod is recommended.
rabies. reactions,
urticaria, rash.
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

VAXIRAB

SIDE EFFECTS
NAME AND ADVERSE
OF CLASSIFICATIO MECHANISM OF CONTRAINDICATIO INDICATION EFFECTS NURSING
DRUG N ACTION N RESPONSIBILITI
ES
Rabies Viral  Pharmacology:  There are no Pre-exposure  In rare Monitor patient
Vaxira Vaccines. VaxiRab N absolute or post- cases, for adverse or
b contains highly contraindicatio exposure local side effects.
concentrated, ns after prophylaxis reactions Monitor patient’s
inactivated exposure to against rabies. including response to
rabies virus that rabies. lymphade vaccine.
has been  The vaccine nopathy
cultivated in should not be may be
primary chick administered observed.
embryo to subjects  Transient
fibroblast cell with a history fever can
cultures (PCEC). of a severe occur
VaxiRab N hypersensitivit following
produces high y reaction to vaccinatio
titers of any of the
n.
ingredients in
neutralizing  Despite
the vaccine
antibodies the high
and should
against rabies receive an degree of
virus whether alternate purity of
given before or rabies vaccine the
after exposure. if a suitable vaccine,
 Pharmacokinetic product is there is a
s: The available. theoretica
inactivated virus l risk of
contained in inducing
VaxiRab N anaphylac
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

vaccine undergo tic

phagocytosis by reactions
macrophages in
and is then persons
transported with sensitized
them into the to avian
reticuloendotheli proteins.
al tissue, where
 Rabies
they stimulate
vaccine
the immune
system to may
produce virus- cause
neutralizing anti- erythema
rabies multiform
antibodies. e.
 Pain at
the site of
injection
 Headache
 Nausea
 Rash
 Stomach
pain or
discomfor
t
 Weaknes
s
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

EQUIRAB

SIDE
NAME EFFECTS
OF CLASSIFICATION MECHANISM CONTRAINDICATION INDICATION AND NURSING
DRUG OF ACTION ADVERSE RESPONSIBILITIES
EFFECTS
Equirab is a sterile Equirab 1500 Equirab should be use It is indicated Immediate or  Provide
Equirab non-pyrogenic Injection is with extreme caution in in individuals delayed patient
solution for given along subjects with a history with category hypersensitive Isolation
intramuscular with a rabies of allergic symptoms or III exposures type reactions  Wash hands
administration, it vaccine to hypersensitivity to horse (in-depth may be before and
contains antiviral prevent serum. Despite the high injury). RIG developed on after patient
substances infection degree of purification of neutralizes administration contact to
obtained from the caused by the the serum, it is the rabies of Equirab. prevent self-
blood serum of rabies virus to recommended to virus at the The observed contamination
healthy horses that individuals perform a skin test inoculation immediate and spread of
has been with before administering site before reactions are disease
immunized against suspected Anti-Rabies Serum the immune anaphylactoid  Give
rabies by rabies (Equine). system reactions with emotional and
vaccination, In exposure. It responds to hypotension, spiritual
addition it also works by the vaccine dyspnea, support to the
contains the neutralizing by the urticaria. family by
antimicrobial agent the virus at the production of Delayed helping them
cresol. wound site rabies virus- reactions cope with the
within a few neutralizing consist of patient’s
hours before antibodies. inflammatory symptoms and
the immune reaction, fever, probable
system pruritis, rash or death
responds to urticaria,  Darken the
the vaccine. adenopathy room, provide
and a quiet
arthralagia. environment
 The patient
should not be
bathed and
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

must not have

any running
water in the
room.
 Continuously
monitor
cardiac and
respiratory
function
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

CEPHALEXIN

SIDE EFFECTS AND

NAME OF ADVERSE
DRUG CLASSIFICATI MECHANIS CONTRAINDICATI INDICATION EFFECTS NURSING
ON M OF ON RESPONSIBILITIE
ACTION S
Cephalexin is in Cephalexin  Antimicrobia Cephalexin is More common Watch for seizures;
Cephalexin a class of is a l resistance, indicated for notify physician
medications bactericidal viral the treatment  Diarrhea immediately if
called agent that infection of certain patient develops or
Rare
cephalosporin acts by the  Cephalospo infections increases seizure
antibiotics. inhibition of rin caused by activity. Monitor
 Abdominal or
bacterial cell- hypersensiti susceptible signs of
wall bacteria. stomach pain pseudomembranou
vity,
synthesis. penicillin These  blistering, s colitis, including
hypersensiti infections peeling, or diarrhea, abdominal
vity include loosening of the pain, fever, pus or
 Renal respiratory skin mucus in stools,
failure, renal tract infections,  chills and other severe or
impairment otitis media, prolonged GI
skin and skin  clay-colored problems (nausea,
 C. difficile- stools
associated structure vomiting,
diarrhea, infections,  cough heartburn).
diarrhea, bone  dark urine
pseudomem infections, and
genitourinary  diarrhea
branous
colitis tract infections.  dizziness
 Pregnancy  fever
 Breast-  general
feeding tiredness and
 Coagulopat weakness
hy, vitamin
K deficiency  headache
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

 Diabetes  itching or rash

mellitus  joint or muscle
 Geriatric pain
 light-colored
stools
 loss of appetite
 nausea and
vomiting
 red skin lesions,
often with a
purple center
 red, irritated
eyes
 sore throat
 sores, ulcers, or
white spots in
the mouth or on
the lips
 unpleasant
breath odor
 unusual
tiredness or
weakness
 upper right
abdominal or
stomach pain
 vomiting of
blood
 yellow eyes or
skin
Incidence not
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

known

 Abdominal or
stomach
cramps or
tenderness
 back or leg
pains
 black, tarry
stools
 bleeding gums
 bloating
 blood in the
urine or stools
 chest pain
 coughing up
blood
 diarrhea, watery
and severe,
which may also
be bloody
 difficulty with
breathing or
swallowing
 fast heartbeat
 general body
swelling
 hives
 increased
menstrual flow
or vaginal
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

bleeding
 increased thirst
 large, hive-like
swelling on the
face, eyelids,
lips, tongue,
throat, hands,
legs, feet, or
sex organs
 loss of appetite
 nosebleeds
 pain
 painful or
difficult
urination
 pale skin
 paralysis
 pinpoint red
spots on the
skin
 prolonged
bleeding from
cuts
 puffiness or
swelling of the
eyelids or
around the
eyes, face, lips,
or tongue
 red or black,
tarry stools
 red or dark
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

brown urine
 swollen or
painful glands
 tightness in the
chest
 unusual
bleeding or
bruising
 unusual weight
loss
 watery or
bloody diarrhea
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

SALBUTAMOL

SIDE EFFECTS
NAME OF AND ADVERSE
DRUG CLASSIFICATI MECHANISM CONTRAINDICATI INDICATION EFFECTS NURSING
ON OF ACTION ON RESPONSIBILITI
ES
Bronchodilator It relieves nasal  Hypersensiti  To control  Nervousn  Assess
Salbutamol (therapeutic); congestion and vity to and ess lung
adrenergics reversible adrenergic prevent  Restless sounds,
(pharmacologic) bronchospasm amines reversible ness PR and
by relaxing the  Hypersensiti airway  Tremor BP before
smooth vity to obstructio  Headach drug
muscles of the fluorocarbon n caused e administra
bronchioles. s by asthma  Insomnia tion and
The relief from or chronic  Chest during
nasal obstructiv pain peak of
congestion and e medicatio
 Palpitatio
bronchospasm pulmonary n.
ns
is made disorder  Observe
 Angina
possible by the (COPD) fore
following  Arrhythmi
 Quick paradoxic
mechanism that as
relief for al spasm
takes place  Hyperten
bronchosp and
when sion
asm withhold
Salbutamol is  Nausea medicatio
 For the
administered. and n and
prevention
vomiting notify
of
1) First, it exercise-  Hypergly physician
binds to induced cemia if condition
the bronchosp  Hypokale occurs.
beta2- asm mia  Administer
adrener  Long-term PO
gic control medicatio
receptor agent for ns with
s in the patients meals to
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

airway with minimize

of the chronic or gastric
smooth persistent irritation.
muscle bronchosp  Extended-
which asm release
then tablet
leads to should be
the swallowed
activatio -whole. It
n of the should not
adenyl be
cyclase crushed or
and chewed.
increase  If
d levels administer
of cyclic- ing
3’5’- medicatio
adenosi n through
ne inhalation,
monoph allow at
osphate least 1
(cAMP). minute
2) When between
cAMP inhalation
increase of aerosol
s, medicatio
kinases n.
are  Advise the
activate patient to
d. rinse
3) Kinases mouth
inhibit with water
the after each
phospho inhalation
rylation to
of minimize
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

myosin dry mouth.

and  Inform the
decreas patient
e that
intracell Albuterol
ular may
calcium. cause an
4) Decreas unusual or
ed in bad taste.
intracell
ular
calcium
will
result to
the
relaxatio
n of the
smooth
muscle
airways.
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

ISONIAZID

SIDE EFFECTS
NAME AND
OF CLASSIFICATIO MECHANISM CONTRAINDICATI INDICATION ADVERSE NURSING
DRUG N OF ACTION ON EFFECTS RESPONSIBILITIES
antituberculosis The Isoniazid is Isoniazid is an More common Be alert for signs of
Isoniazid agents antimicrobial contraindicated in antibiotic used to  Clumsin drug-induced hepatitis,
activity of INH patients who treat ess or including anorexia,
is selective for develop severe mycobacterial unsteadi abdominal pain,
mycobacteria, hypersensitivity infections; most ness severe nausea and
likely due to its reactions, including commonly use in  dark vomiting, yellow skin
ability to inhibit drug -induced combination with urine or eyes, fever, sore
mycolic acid hepatitis; previous other  loss of throat, malaise,
synthesis, isoniazid- antimycobacterial appetite weakness, facial
which associated hepatic agents for the  nausea edema, lethargy, and
interferes with injury; severe treatment of or unusual bleeding or
cell wall adverse reactions active or latent vomiting bruising. Report these
synthesis, to isoniazid such as tuberculosis.  numbne signs to the physician
thereby drug fever, chills, Antibacterial ss, or nursing staff
producing a arthritis; and acute agent used tingling, immediately.
bactericidal liver disease of any primarily as a burning,
effect. etiology. tuberculostatic. It or pain
remains the in hands
treatment of and feet
choice for  unusual
tuberculosis. tirednes
s or
weakne
ss
 yellow
eyes or
skin
Rare
 Blurred
vision or
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

loss of
vision,
with or
without
eye pain
 convulsi
ons
(seizure
s)
 fever
and sore
throat
 joint
pain
 mental
depressi
on
 mood or
other
mental
changes
 skin
rash
 unusual
bleeding
or
bruising
More common
 Diarrhea
 stomach
pain
For injection
form
 Irritation
at the
place of
CORTEZ, ALESSANDRA FRANCHESCA E.
BSN2-C

injection