DRUG NAME INDICATION ACTION ADVERSE CONTRAINDICATION NURSING

REACTION RESPONSIBILITIES

GENERICNAME: Dinitrate:Prevention Stimulates Frequent:Headache DRUG: Baseline assessment

and treatment of intracellularcyclic (may be severe) Alcohol, antihypertensives Record onset,type
Isosorbide angina pectoris due guanosine occurs mostly in early (e.g.,amLODIPine, (sharp,dull,squeezing),
Dinitrate to coronary artery monophosphate. therapy,diminishes lisinopril,valsartan) may radiation,location,
disease. rapidly in intensity, increase risk of orthostatic intensity, duration of
Mononitrate: Therapeutic Effect: usually disappears hypotension. anginal
BRAND NAME:
Treatment Relaxes vascular during continued Sildenafil,tadalafil, pain;precipitating
Isordil (immediate release smooth muscle of treatment. Occasional: vardenafil may potentiate factors(exertion,
only) and prevention arterial,venous Transient flushing of hypotensive effects emotional stress).
of angina pectoris vasculature. face/neck,dizziness, (concurrent use of these
DOSAGE: due to coronary Decreases preload, weakness, orthostatic agents is contraindicated). If headache occurs
artery disease also afterload, cardiac hypotension, during
5 mg oxygen demand managementtherapy,
used to abort acute nausea,vomiting,
Sl PRN for chest anginal episode. restlessness.Gl administer medication
pain upset,blurred vision, with meals.
dry mouth.
CLASSIFICATION: Intervention/evaluation
Sublingual:Frequent:
Assist with ambulation
Burning,tingling at
Nitrates, angina if light-headedness,
oral point of
dizziness occurs.Assess
dissolution
for facial/neckflushing.
Discontinue if blurred
vision occurs.Severe Monitor number of
orthostatic anginal episodes,
hypotension orthostatic B/P.
manifested by
syncope, Patient/family teaching
pulselessness,
cold/clammy skin,  Do not chew,crush,
diaphoresis has been dissolve,or divide
reported. Tolerance sublingual,extended-
may occur with release,
repeated, prolonged sustainedrelease
therapy, but may not forms.
occur with extended-  Take sublingual
release form.Minor tablets while sitting
tolerance with down.
intermittent use of  Go from lying to
sublingual standing slowly
tablets.High dosage (prevents dizziness
tends to produce effect).
severe headache.  Take oral form on
empty stomach
(however,if
headache occurs
during managemen
therapy, take
medication with
meals).
 Dissolve sublingual
tablet under
tongue;do not
swallow.
 Avoid alcohol
(intensifieshypotensi
ve effect).
 If alcohol is ingested
soon after taking
nitrates,possible
acute hypotensive
episode(marked
drop in
B/P,vertigo,pallor)
may occur.
 Report
signs/symptoms of
hypotension, angina
DRUG NAME INDICATION ACTION ADVERSE CONTRAINDICAT NURSING
REACTION ION RESPONSIBILITIES

GENERICNAME: Prescribed for Albendazole is Central Nervous System If you are allergic to Pre-Administration:
tapeworm infections, found to inhibit the Headache, any ingredient in
Albendazole hydatid cyst disease, polymerization of seizures,confusion, raised albendazole or to Follow 10 R's of giving
cysticercosis or the parasite tubulin intracranial pressure, benzimidazoles medication Intra-
neurocysticercosis, into microtubules. dizziness/vertigo, signs Administration:
BRAND NAME:
capillariasis, There is a higher that meningeal sings.
 Give oral drug with
Albenza cutaneous larva affinity of
Skin full glass of water.
migrans,giardiasis, albendazole to the
Reversible hair  Make sure that drug
microsporidiosis parasite tubulin and
DOSAGE: loss,infection, is taken.
including Septata so the activity is
hypersensitivity  In young
400 mg intestinalis infection, mediated mainly
including rash and children,the tablets
intestinal parasites in against the parasite
hives,allergic reactions. should be crushed or
immigrants, rather than on the
CLASSIFICATIO chewed and
strongyloidiasis, host.The loss of the
N: Gastrointestinal swallowed with
trichinosis, cytoplasmic
Abdominal pain, glass of water.
trichostrongyliasis.I t microtubules leads
Anthelmintic nausea/vomiting.
works by killing to impaired uptake
sensitive parasites. of glucose by the Genitourinary-Acute
larval and adult kidney failure, dark
stages of the urine.
parasites.The worm
is then unable to Liver-
maintain energy abnormal liver functions
production, which tests, inflammation of
leads to liver
immobilization and
eventual death. A Blood- decrease in the
secondary actiob number of white blood
may be the cells,
inhibition of enzyme thrombocytes,hemoglobi
fumarate reductase, n
whicjh is helminth-
specific. Miscellaneous- fever
DRUG NAME INDICATION ACTION ADVERSE CONTRAINDICATION NURSING
REACTION RESPONSIBILITIES

GENERICNAME: GI Norm GI Norm is a CNS: headache, Contraindicated in:  Assess for nausea,

Suspension is dopamine insomnia Known vomiting,
Domperidone indicated in antagonist with hypersensitivity/intolerance; abdominal
adults and anti-emetic GI: dry mouth Concurrent use of distention, and
BRAND NAME: children for the properties, GI ketoconazole; bowel sounds
GU: amenorrhea,
relief of the Norm does not before and after
impotence Prolactinoma;
G1 norm symptoms of readily cross the administration.
nausea and blood-brain Conditions where GI  Monitor BP
Derm: hot flushes,
vomiting. barrier. In GI stimulation is dangerous (sitting, standing,
DOSAGE: rash
Norm users, including GI lying down) and
10mg especially in Endo: galactorrhea, hemorrhage/mechanical pulse before and
adults, gynecomastia, obstruction/perforation; periodically during
extrapyramidal hyperprolactinemia therapy. May cause
CLASSIFICATION: Lactation: Breast feeding is
side effects are prolonged QT
not recommended unless
Dopamine very rare, but GI interval,
potential benefits outweigh
Antagonist Norm promotes tachycardia, and
potential risks.
the release of orthostatic
prolactin from hypotension,
the pituitary. Its especially in
anti-emetic patients older than
effect may be 60 yr or taking >30
due to a mg/day.
combination of  Monitor for
peripheral symptoms related
(gastrokinetic) to
effects and hyperprolactinemia
antagonism of (menstrual
dopamine abnormalities,
receptors in the galactorrhea,
chemoreceptor sexual
trigger zone, dysfunction).
which lies  Instruct patient to
outside the take as directed.
blood-brain Advise patient to
barrier in the avoid grapefruit
area postrema. juice during
Animal studies, therapy.
together with the  Advise patient to
low notify health care
concentrations professional if
found in the galactorrhea
brain, indicate a (excessive or
predominantly spontaneous flow
peripheral effect of breast milk),
of GI Norm on gynecomastia
dopamine (excessive
receptors. development of
male mammary
gland), menstrual
irregularities
(spotting or
delayed periods),
palpitations,
irregular heartbeat
(arrhythmia),
dizziness, or
fainting occur.
 Advise female
patient to notify
health care
professional if
pregnancy is
planned or
suspected or if
breast feeding.
DRUG NAME INDICATI ACTION ADVERSE REACTION CONTRAINDICATION NURSING
ON RESPONSIBILITIES

GENERICNAM Osteoarthriti Inhibits the CV: HF, MYOCARDIAL Contraindicated in:  Assess range of

E: s. enzyme COX- INFARCTION, STROKE,  Hypersensitivity; motion, degree of
Rheumatoid 2. This THROMBOSIS, edema, Cross-sensitivity may exist swelling, and pain in
BRAND NAME: arthritis. enzyme is hypertension with other NSAIDs, affected joints before
Ankylosing required for Derm: DRUG REACTION including aspirin; and periodically
DOSAGE:
spondylitis. the synthesis WITH EOSINOPHILIA History of allergic-type throughout therapy.
CLASSIFICATI Juvenile of AND SYSTEMIC reactions to sulfonamides;  Assess patient for
ON: rheumatoid prostaglandins. SYMPTOMS History of asthma, allergy to
arthritis. Has analgesic, (DRESS), EXFOLIATIVE urticaria, or allergic-type sulfonamides,
nonsteroidal anti- Acute pain. anti- DERMATITIS, STEVENS- reactions to aspirin or aspirin, or NSAIDs.
inflammatory Primary inflammatory, JOHNSON SYNDROME other NSAIDs, including Patients with these
drugs (NSAIDs) dysmenorrhe and antipyretic (SJS), TOXIC the aspirin triad (asthma, allergies should not
a. properties. EPIDERMAL nasal polyps, and severe receive celecoxib.
Therapeutic NECROLYSIS (TEN), rash hypersensitivity reactions  Assess patient for
Effect(s): F and E: hyperkalemia to aspirin); skin rash frequently
Decreased GI: GI BLEEDING, Advanced renal disease; during therapy.
pain and abdominal pain, diarrhea, Severe hepatic Discontinue at first
inflammation dyspepsia, flatulence, impairment; sign of rash; may be
caused by nausea Coronary artery bypass life-threatening. SJS
osteoarthritis, Neuro: dizziness, headache, graft (CABG) surgery; may develop. Treat
rheumatoid insomnia OB:  Avoid use after 30 symptomatically;
arthritis, wk gestation. may recur once
ankylosing treatment is stopped.
spondylitis, or Use Cautiously in:  Monitor for signs
juvenile and symptoms of
Cardiovascular disease or
rheumatoid DRESS (fever, rash,
risk factors for
arthritis. lymphadenopathy,
cardiovascular disease
Decreased facial swelling)
(may ↑ risk of serious
acute pain. periodically during
cardiovascular thrombotic
Pharmacokinet events, myocardial
ics infarction, and stroke,
especially with prolonged
use or use of higher
doses); avoid use in
patients with recent MI or
HF;
Pre-existing renal disease,
heart failure, liver
dysfunction, concurrent
diuretic, or ACE inhibitor
therapy (↑ risk of renal
impairment);
History of peptic ulcer
disease or GI bleeding,
long duration of NSAID
use, smoking, alcohol use,
advanced liver disease,
coagulopathy, and poor
general health (↑ risk of
GI bleeding);
Hypertension or fluid
retention;
Renal impairment (may
precipitate acute renal
failure);
Serious dehydration
(correct deficits before
therapy. Discontinue
therapy if symptoms
occur.
 Do not confuse
Celebrex (celecoxib)
with Celexa
(citalopram) or
Cerebyx
(fosphenytoin).
 Use lowest effective
dose for shortest
period of time.
 PO May be
administered without
regard to meals.
Capsules may be
opened and sprinkled
on applesauce and
ingested immediately
with water. Mixture
may be stored in the
refrigerator for up to
6 hr.
administering);
Patients who are known or
suspected to be poor
CYP2C9 metabolizers (↓
initial dose by 50%; in
patients with juvenile
rheumatoid arthritis, use
alternative treatment);
Pre-existing asthma;
OB:  Use at or after 20 wk
gestation may cause fetal
or neonatal renal
impairment; if treatment is
necessary between 20 wk
and 30 wk gestation, limit
use to the lowest effective
dose and shortest duration
possible;
Pedi:  Safety not
established in children <2
yr or for longer than 6 mo;
Geri:  ↑ risk of GI
bleeding in older adults
DRUG NAME INDICATION ACTION ADVERSE CONTRAINDICATION NURSING
REACTION RESPONSIBILITIES

GENERICNAME:

BRAND NAME:

DOSAGE:

CLASSIFICATION
:
gamma aminobutyric
acid gaba analogues
DRUG NAME INDICATION ACTION ADVERSE CONTRAINDICATION NURSING
REACTION RESPONSIBILITIES
GENERICNAME:

BRAND NAME:

DOSAGE:

CLASSIFICATION
: