Miron Andreea, CRP II

(EN)
Domain / Subdomain: Medicine/Genetics
Entry term: Down Syndrome
Grammatical information: compound noun, singular
Synonyms: trisomy 21, mongolism,
Variants: Down’s syndrome, DS (initialism), Down’s (short form)

Definition: congenital disorder caused by the presence in the human genome of extra genetic

material from chromosome 21 and causes common physical signs as: a small head, flattened face,
short neck, up-slanted eyes, low-set ears, enlarged tongue and lips, and sloping underchin.
Source: Britannica - Down syndrome
Context:
Source:
Usage notes:
1) This term does not have a plural form
2) The Down syndrome is a preferred term
3) The synonym trisomy 21 is used only in specialized communication (medical)
4) The synonym mongolism is outdated, and should be avoided because it is considered
offensive
5) The short form Down’s and the initialism DS are used for economy of speech after the full
form Down syndrome has been mentioned

Domain/Subdomain: (ex)

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If we have acronyms -used for economy of speech

Miron Andreea, CRP II

(RO)
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