Chemistry lab 4

Laura Pérez López e Irene Raisuni Rodríguez

MATERIAL AND CHEMICALS

• Erlenmeyer, is a flask having a wide base,

narrow neck, and conical form, convenient
in laboratory experimentation for swirling
liquids by hand.
MATERIAL AND CHEMICALS

• Pipette and liquid aspirator, is a

slender tube attached to or
incorporating a bulb, for
transferring or measuring out small
quantities of liquid, especially in a
laboratory.
MATERIAL AND CHEMICALS

• A beaker is a cylindrical glass vessel for

mixing, measuring, and pouring liquid
chemicals. Along with things like
Bunsen burners and test tubes, a well-
stocked chemistry lab has plenty of
beakers.
MATERIAL AND CHEMICALS

• Laboratory thermometers are

devices used to measure
temperature. There are many types
of lab thermometers such as
differential, mechanical, logging, etc.
MATERIAL AND CHEMICALS

• Graduated cylinder, is a tall narrow

container with a volume scale used
especially for measuring liquids.
MATERIAL AND CHEMICALS

• Kitasato flask, is a flask that is included

among the glassware of the
laboratory. It is, in its most basic
explanation, an Erlenmeyer flask to
which a small detachment tube or
lateral nozzle has been added. Used in
experiments with water, such as
distillation, gas collection, vacuum
filtration, among others.
MATERIAL AND CHEMICALS

• A Büchner funnel is a piece of

laboratory equipment used in filtration
It is traditionally made of porcelain,
but glass and plastic funnels are also
available. On top of the funnel-shaped
part there is a cylinder with
a fritted glass disc/perforated plate
separating it from the funnel.
MATERIAL AND CHEMICALS

• Filter paper is a semi-permeable paper

barrier placed perpendicular to a liquid
or air flow. It is used to separate fine
solid particles from liquids or gases.
MATERIAL AND CHEMICALS

• Salicylic Acid is a type of beta hydroxy acid

(BHA) and phenolic acid with a chemical
formula C7H6O3. It is a BHA found as a natural
compound in plants. It functions as a plant
hormone. This lipophilic
monohydroxybenzoic acid is a derivative of
salicin metabolism.
MATERIAL AND CHEMICALS

• An Acid anhydride can be defined as a non-

metal oxide which forms an acidic solution
when reacted with water. In organic
chemistry, it is a functional group consisting
of 2 acyl groups combined by an oxygen
atom.
MATERIAL AND CHEMICALS

• Sulfuric acid (H2S04) is a corrosive substance,

destructive to the skin, eyes, teeth, and
lungs. Severe exposure can result in death.
Workers may be harmed from exposure to
sulfuric acid. The level of exposure depends
on dose, duration, and type of work being
done.
STEPS TO FOLLOW
1.Pour, in a 250 mL Erlenmeyer flask, the following reagents:
• Salicylic acid (5 g)
• Acetic anhydride (10 mL)
• Concentrated sulphuric acid (four or five drops)
2.Stir the mix gently. The temperature will rise to about 50 °C (it is an exothermic reaction)
3.In approximately 15 minutes, the temperature of the solution will cool off to 35 °C and the flask
contents will be a solid mass of aspirin crystals.
4.Add, gently and slowly, 2 mL of very cold water (Note: Acetic anhydride reacts violently with water
and the mixture may splash) and stir the mix gently. Once this addition is finished, add 49 mL more
cold water and cool to 0°C in an ice bath.
5.Filter the mix using the Kitasato flask and the Buchner funnel. Pour very cold water into the flask
to clean it up. Aspirin must be pressed on the filter to remove as much water as possible.
6.Remove the remaining water from the aspirin by pressing the solid mass in a piece of filter paper.
 QUESTIONS

1.Aspirin is used to reduce fever and relieve mild to moderate pain from conditions such as
muscle aches, toothaches, common cold, and headaches. It may also be used to reduce pain
and swelling in conditions such as arthritis. Aspirin is known as a salicylate and a nonsteroidal
anti-inflammatory drug (NSAID). It works by blocking a certain natural substance in your body
to reduce pain and swelling.
2.Salicylic acid interacts with acetic anhydride in presence of few drops of concentrated
sulphuric acid to produce aspirin and a molecule of acetic acid. The purpose of adding
sulphuric acid (catalyst) is to aid and augent the process of detaching the acetate ion
(CH3COO–) from acetic anhydride which ultimately gets associated with H+ ion from phenolic
hydroxy group in salicylic acid to be eliminated as a mole of acetic acid.
 QUESTIONS

3.-
Group conclusion

We have really liked the practice, because we have been able to

see how medicines can be created through chemistry. It was a bit
tiring having to stir for so long and we didn't get much
performance, but even so we found it a very interesting practice
and it shows us the importance of chemistry in life and in this
case in the medicines that help us to fix our problems.
At times we almost messed it up, but in the end it turned out well
and it was very cool to see how we were able to create
something as useful as aspirin.
LAB PROCESS ( Video about hoy we madre the
experiment)