NAME:

SECTION:
SUBJECT & ROTATION:
CLINICAL INSTRUCTOR:

DRUG STUDY

NAME OF MECHANISM DOSAGE INDICATION CONTRAINDICATION REACTION NURSING

DRUG OF ACTION ALERT

Generic Thiamine Dosage: Thiamine is Contraindications Side effects: Assessment &

name: combines with Thiamine taken for Hypersensitivity Side effects of Drug Effects
Thiamine adenosine Deficiency conditions thiamine
triphosphate Adult: IV/IM related to low In pregnancy (doses include: Record
(ATP) in the 50–100 mg levels of exceeding the patient's
Brand name: liver, kidneys, t.i.d. thiamine, recommended daily warmth dietary history
Vitamin B1 and leukocytes Child: IV/IM including average) severe allergic carefully as an
to produce 10–25 mg t.i.d. beriberi and Acute thiamine deficiency reaction essential part
Drug Class: thiamine inflammation of reported with dextrose (anaphylaxis) of vitamin
B Vitamins; diphosphate. Beriberi the nerves administration; use skin replacement
Vitamins, Thiamine Adult: IV/IM (neuritis) caution when thiamine discoloration therapy.
Water- diphosphate acts 10–500 mg associated with status uncertain sweating Collaborate
Soluble as a coenzyme t.i.d. for 2 wk pellagra or Hypersensitivity reactions restlessness with
in carbohydrate or until on pregnancy. reported following rapid swelling physician,
metabolism, in normal diet Thiamine is repeated parenteral doses of the skin dietitian,
transketolation Child: IV/IM also used for Parenteral production itching patient, and
reactions, and in 10–50 mg t.i.d. digestive may contain aluminum; hives responsible
the utilization of until on normal problems use caution in patients fluid in the family
hexose in the diet including poor with impaired kidney lungs member in
hexose- appetite, (renal) function (pulmonary developing a
monophosphate Dietary ulcerative Evaluate for additional edema) diet teaching
shunt. Supplement colitis, and vitamin deficiencies if weakness plan that can
Adult: PO 15– ongoing patient diagnosed with tightness of the be sustained
30 mg/d diarrhea. thiamin deficiency; single throat by patient.
Child: PO 10– vitamin deficiencies are nausea Note: Body
50 mg/d rare requirement of
Pregnancy and Lactation thiamine is
Frequency: directly
10 to 20 mg IM Thiamine (injectable) is Adverse proportional
three times generally acceptable effects: to
daily for up to during pregnancy carbohydrate
2 weeks. Controlled studies in intake and
Thereafter, use pregnant women show no metabolic
an oral evidence of fetal risk rate;
therapeutic Only use thiamine in requirement
multivitamin doses exceeding the increases
preparation recommended daily when diet
containing 5 to average during pregnancy consists
10 mg thiamine with caution if benefits predominantly
daily for one outweigh risks of
month Animal studies show risk carbohydrates.
and human studies are not Total absence
Classification: available, or neither of dietary
Vitamins animal nor human studies thiamine
were done produce
Thiamine is safe to use deficiency
while breastfeeding state in about
3 wk.