Professional Documents
Culture Documents
AGARTALA, TRIPURA
SUBMITTED BY: -
ADRIJA DAS
XII, B
ROLL. NO: - 17
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Certificate
This is to certify that this “Biology Investigatory Project”
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ACKNOWLEDGEMENT
I have taken efforts in this project. However, it would
not have been possible without the kind support and help of
many individuals.
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INDEX
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AIM / OBJECTIVE
My aim of this project is :-
1. To study on cancers
2. To discuss on their classification
3. To know how it develops in our body
4. it’s risk factors
5. Symptoms
6. types of cancer
7. how to diagnose cancer
8. stages of cancer
9. how to treat cancer
10. side effects and when to
consult healthcare provider.
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INTRODUCTION
CANCER
Learning that you have cancer can be stressful and
frightening. Knowing what to expect — from diagnosis to
recovery — can empower you and help you take control of your
health. This is a general overview of what cancer is, symptoms to
watch for, how it’s detected, treatments and post-treatment care.
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What is cancer?
Cancer is a large group of diseases with one thing in common: They
all happen when normal cells become cancerous cells that multiply and
spread.
Cancer is the second most common cause of death in the U.S. But
fewer people are dying of cancer now than 20 years ago. Early detection and
innovative treatments are curing cancer and helping people with cancer live
longer. At the same time, medical researchers are identifying independent
risk factors linked to developing cancer to help prevent people from
developing cancers.
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What is the difference between a normal cell and a
cancerous cell?
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How does cancer start in your body?
For example, a tumor in your breast may spread to your lungs, making it
hard for you to breathe. In some types of blood cancer, abnormal cells in
your bone marrow make abnormal blood cells that multiply uncontrollably.
Eventually, the abnormal cells crowd out normal blood cells.
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What are the risk factors
and causes of cancer?
Pathogens: Human papillomavirus (HPV), EBV or Epstein-Barr
virus, hepatitis viruses B and C, Kaposi's sarcoma-associated herpes virus
(KSHV), Merkel cell polyomavirus, Schistosoma spp., and Helicobacter pylori;
other bacteria are being researched as possible agents.
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Genetics: A number of specific cancers have been linked to human genes
and are as follows: breast, ovarian, colorectal, prostate, skin, and melanoma;
the specific genes and other details are beyond the scope of this general
article so the reader is referred to the National Cancer Institute for more
details about genetics and cancer.
It is important to point out that most everyone has risk factors for
cancer and is exposed to cancer-causing substances (for example, sunlight,
secondary cigarette smoke, and X-rays) during their lifetime, but many
individuals do not develop cancer. In addition, many people have genes
that are linked to cancer but do not develop it. Why? Although researchers
may not be able to give a satisfactory answer for every individual, it is clear
that the higher the amount or level of cancer-causing materials a person is
exposed to, the higher the chance the person will develop cancer. In
addition, people with genetic links to cancer may not develop it for similar
reasons (lack of enough stimulus to make the genes function). In addition,
some people may have a heightened immune response that controls or
eliminates cells that are or potentially may become cancer cells. There is
evidence that even certain dietary lifestyles may play a significant role in
conjunction with the immune system to allow or prevent cancer cell
survival. For these reasons, it is difficult to assign a specific cause of cancer
to many individuals.
Recently, other risk factors have been added to the list of items that
may increase cancer risk. Specifically, red meat (such as beef, lamb, and
pork) was classified by the International Agency for Research on Cancer as a
high-risk agent for potentially causing cancers; in addition processed meats
(salted, smoked, preserved, and/or cured meats) were placed on the
carcinogenic list. Individuals that eat a lot of barbecued meat may also
increase risk due to compounds formed at high temperatures. Other less-
defined situations that may increase the risk of certain cancers
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include obesity, lack of exercise, chronic inflammation, and hormones,
especially those hormones used for replacement therapy. Other items such
as cell phones have been heavily studied. In 2011, the World Health
Organization classified cell phone low-energy radiation as "possibly
carcinogenic," but this is a very low-risk level that puts cell phones at the
same risk as caffeine and pickled vegetables. Proving that a substance does
not cause or is not related to increased cancer risk is difficult. For example,
antiperspirants are considered to possibly be related to breast cancer by
some investigators and not by others. The official stance of the NCI is that
"additional research is needed to investigate this relationship and other
factors that may be involved." This unsatisfying conclusion is presented
because the data collected so far is contradictory. Other claims that are
similar require intense and expensive research that may never be done.
Reasonable advice might be to avoid large amounts of any compounds even
remotely linked to cancer, although it may be difficult to do in complex,
technologically advanced modern societies.
You can reduce your risk by changing some of your lifestyle choices:
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Nagging cough or hoarseness
Other signs or symptoms may also alert you or your doctor to the possibility of
Anyone with these signs and symptoms should consult their doctor; these
symptoms may also arise from noncancerous conditions.
Many cancers will present with some of the above general symptoms
but often have one or more symptoms that are more specific for the cancer
type. For example, lung cancer may present with common symptoms of
pain, but usually, the pain is located in the chest. The patient may have
unusual bleeding, but the bleeding usually occurs when the patient coughs.
Lung cancer patients often become short of breath and then become very
fatigued.
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Because there are so many cancer types (see next section) with so many
nonspecific and sometimes more specific symptoms, the best way to learn
about the signs and symptoms of specific cancer types is to spend a few
moments researching symptoms of a specific body area in question.
Conversely, a specific body area can be searched to discover what signs and
symptoms a person should look for in that area that is suspected of having
cancer. The following examples are two ways to proceed to get information
on symptoms:
Use a search engine (Google, Bing) to find links to cancer by listing the
symptom followed by the term "cancer" or if you know the type you
want information about, (lung, brain, breast) use MedicineNet’s
search option. For example, listing "blood in urine and cancer" will
bring a person to websites that list possible organs and body systems
where cancer may produce the listed symptoms.
Use a search engine as above and list the suspected body area and
cancer (for example, bladder, and cancer), and the person will see sites
that list the signs and symptoms of cancer in that area (blood in
urine is one of several symptoms listed).
Be aware that many websites are not necessarily reviewed by a health
care professional and could contain information that is not accurate.
Your health care professional is ultimately the best resource if you
have concerns.
Besides, if the cancer type is known (diagnosed), then even more specific
searches can be done listing the diagnosed cancer type and whatever may
be questioned about cancer (symptoms, tumor grades, treatments,
prognosis, and many other items).
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What are the five different types of
cancer?
There are over 200 types of cancer; far too numerous to include in this
introductory article. However, the NCI lists several general categories (see
list in the first section of this article). This list is expanded below to list more
specific types of cancers found in each general category; it is not all-
inclusive and the cancers listed in quotes are the general names of some
cancers:
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meningiomas, pituitary adenomas, vestibular schwannomas, primary
CNS lymphomas, and primitive neuroectodermal tumors.
Not included in the above types listed are metastatic cancers; this is
because metastatic cancer cells usually arise from a cell type listed above
and the major difference from the above types is that these cells are now
present in a tissue from which the cancer cells did not originally develop.
Consequently, if the term "metastatic cancer" is used, for accuracy, the
tissue from which the cancer cells arose should be included. For example,
a patient may say they have or are diagnosed with "metastatic cancer"
but the more accurate statement is "metastatic (breast, lung, colon, or
another type) cancer with spread to the organ in which it has been
found." Another example is the following: A doctor describing a man
whose prostate cancer has spread to his bones should say the man has
metastatic prostate cancer to bone. This is not "bone cancer," which
would be cancer that started in the bone cells. Metastatic prostate cancer
to bone is treated differently than lung cancer to bone.
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main oncologist will help you to determine what specialists are best to be
members of your treatment team.
Blood tests.
Imaging tests.
Biopsies.
Blood tests
Complete blood count (CBC): A CBC test measures and counts your
blood cells.
Tumor markers: Tumor markers are substances that cancer cells
release or that your normal cells release in response to cancer cells.
Blood protein tests: Healthcare providers use a process called
electrophoresis to measure immunoglobulins. Your immune system
reacts to certain cancers by releasing immunoglobulins.
Circulating tumor cell tests: Cancerous tumors may shed cells.
Tracking tumor cells helps healthcare providers monitor cancer
activity.
Imaging tests
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Magnetic resonance imaging (MRI): MRIs use a large magnet, radio
waves and a computer to create images of your organs and other
structures inside of your body.
Iodine meta-iodobenzylguanidine (MIGB): This nuclear imaging test
helps detect cancer, including carcinoid tumors and neuroblastoma.
Biopsies
Needle biopsy: This test may be called a fine needle aspiration or fine
needle biopsy. Healthcare providers use a thin hollow needle and
syringe to extract cells, fluid or tissue from suspicious lumps. Needle
biopsies are often done to help diagnose breast cancer, thyroid cancer
or cancer in your lymph nodes.
Skin biopsy: Healthcare providers remove a small sample of your
skin to diagnose skin cancer.
Bone marrow biopsy: Healthcare providers remove a small sample of
bone marrow so they can test the sample for signs of disease,
including cancer in your bone marrow.
Endoscopic or laparoscopic biopsy: These biopsies use an endoscope
or laparoscope to see the inside of your body. With both of these
methods, a small cut is made in your skin and an instrument is
inserted. An endoscope is a thin, flexible tube with a camera on the
tip, along with a cutting tool to remove your sample.
Excisional or incisional biopsy: For these open biopsies, a surgeon
cuts into your body and either the entire tumor is removed (excisional
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biopsy) or a part of the tumor is removed (incisional biopsy) to test or
treat it.
Perioperative biopsy: This test may be called a frozen section biopsy.
This biopsy is done while you’re having another procedure. Your
tissue will be removed and tested right away
GENETIC TESTING
Cancer may happen when a single gene mutates or several genes that
work together mutate. Researchers have identified more than 400 genes
associated with cancer development. People who inherit these genes from
their biological parents may have an increased risk of developing cancer.
Healthcare providers may recommend genetic testing for cancer if you have
an inherited form of cancer. They may also do genetic testing to do therapy
that targets specific cancer genes. They use test results to develop a
diagnosis. They’ll assign number or stage to your diagnosis. The higher the
number, the more cancer spread.
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Site of the primary tumor
Tumor size and number of tumors
Lymph node involvement (spread of cancer into lymph nodes)
Cell type and tumor grade (how closely the cancer cells resemble
normal tissue cells)
The presence or absence of metastasis
However, there are two main methods that form the basis for the more
specific or individual cancer type staging. The TMN staging is used for most
solid tumors while the Roman numeral or stage grouping method is used
by some clinicians and researchers on almost all cancer types.
The TNM system is based on the extent of the tumor (T), the extent of
spread to the lymph nodes (N), and the presence of distant metastasis (M).
A number is added to each letter to indicate the size or extent of the primary
tumor and the extent of cancer spread (a higher number means a bigger
tumor or more spread).
The following is how the NCI describes the TNM staging system:
Tis - Carcinoma in situ (CIS; abnormal cells are present but have not spread
to neighboring tissue; although not cancer, CIS may become cancer and is
sometimes called pre-invasive cancer)
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o N1, N2, N3 - involvement of regional lymph nodes (number of
lymph nodes and/or extent of spread)
3. Distant metastasis (M)
o MX - Distant metastasis cannot be evaluated (some clinicians do
not ever use this designation)
o M0 - No distant metastasis
o M1 - Distant metastasis is present
In situ: Abnormal cells are present only in the layer of cells in which
they developed.
Localized: Cancer is limited to the organ in which it began, without
Regional: Cancer has spread beyond the primary site to nearby lymph
nodes or organs and tissues.
Distant: Cancer has spread from the primary site to distant organs or
distant lymph nodes.
Unknown: There is not enough information to determine the stage.
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patient's condition to other health professionals that become involved with
the patients' care.
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What are cancer treatment side effects?
Anemia.
Nausea and vomiting.
Fatigue.
Pain.
Right now, more people are being cured of cancer or living longer with
cancer. In general, people with cancer that were diagnosed and treated
before it could spread have a good outlook.
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How do I live with cancer?
Second cancer
A second cancer is a new cancer. People who have second cancers may have
cancer in the same organ or area of their body as the first cancer, but it’s a
different type of cancer from what it was before. They may also have cancer
in different areas of their bodies. Second cancers are more common, as more
people live longer with cancer.
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Cancer fatigue
Cancer pain
Some cancer treatments have lasting side effects that may cause pain. One
study found that 39% of people who completed cancer treatment had
chronic pain. Peripheral neuropathy is an example of pain that may persist
after treatment.
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What type of cancer do I have?
Has the cancer spread to other areas of my body?
Is my cancer genetic?
What are my chances of survival?
Which treatments do you recommend?
What are the risks and benefits of my treatment?
How long will treatment take?
Will I be able to work during cancer treatment?
Will cancer treatment affect my fertility?
Will I need to stay in the hospital for my treatment?
Would a clinical trial be a good option for me?
CONCLUSION
BIBILOGRAPHY
www.chronicdisease.isdh.in
www.cancer.gov
www.chronicdisease.isdh.in.gov
http://www.essense-of-life.com/moreinfo/minerals/cesium.htm
http://www.advancedhealthplan.com/2cesiumchlorideforcancer2.html
http://www.medicalnewstodays.com/info/cancer-oncology
http://www.cancerresearchuk.org/
http://www.who.int/cancer/
https://my.clevelandclinic.org/health/diseases/12194-cancer
https://www.medicinenet.com/dpr/cancer/what-is-genomic-testing
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nn
THANK
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YOU
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