Quiz 2 and 3 - orgmed

Which among the following G proteins causes the Gq same

activation of phospholipase C?

Among the following, which would be the fastest in Ion channel

producing a response upon proper drug binding?

A functional group that has a highly electron-deficient H ??? or di ba functional goup??

atom is considered a hydrogen bond OH or COOH ata?
Alcohol nalang me ma

Enzyme inhibitors who utilize the reaction catalyzed by Irreversible inhibition

their target enzyme to covalently bond to it are referred
to as

An ionized Asp would have a strong interaction with a opposite?

Covalently bonded enzyme inhibitors are irreversible Both are true

inhibitors. Irreversible inhibitors are more prone to
causing toxicity due to causing a prolonged buildup of
substrate.

A drug uses its binding regions to stay in the binding Only the second statement is true same HAHA
site of a drug target. With just the right force of yay
attraction, a drug will be able to activate its drug target.

Ionic bonds normally provide an initial attractive force Both true>>

between the drug and the target while its usually
London forces that are crucial for binding. Most binding
sites are nonpolar for these reasons.

Which among the following G proteins causes the NONE OF THE CHOINCES BA?? Ano cjhoicess same
activation of adenylate cyclase? none B
B???? Oh noo

Gi

b.
Gs

c.
Gq

d.
None of the choices
Sabi kasi GPCR
Among the following, which would be the slowest in Kinase linked receptors
producing a response upon proper drug binding?

a.

b.
G protein coupled receptors

c.
Ion channel receptors

d.
Nuclear receptors

Check niyo mih ig tama

An enzyme is more likely to strongly bind with a drug subs

that looks like the

QC2 QUIZ 1

For complex
formulations, accuracy in
drug assays is assessed
by:
1.adding known
quantities of the
analyte to the drug
product and
 determining the
percentage recovery
2.applying the method
to a standard
reference material
3.comparing the
results obtained from
a second,
well-established
procedure
4.determining the
percentage accuracy
(or percentage error)
from synthetic
mixtures of the drug
product
5.testing samples
spiked with known
amounts of
impurities

1. The capacity to remain unaffected 1. ROBUSTNESS

by small, but deliberate variations in 2. SPECIFICITY
method parameters and provides an 3. ACCURACY
indication of its reliability during 4. PRECISION
normal usage 5. LINEARITY
2. The ability to assess unequivocally
the analyte in the presence of
components (e.g., impurities,
degradants, matrix, etc.) which may
 be expected to be present
3. Expresses the closeness of
agreement between the
conventional or absolute true value
and the observed value
4. Expresses the closeness of
agreement (degree of scatter)
between a series of measurements
obtained from multiple sampling of
the same homogeneous sample
under the prescribed conditions
5. The ability of an analytical procedure
to obtain test results (within a given
range) which are directly
proportional to the concentration
(amount) of analyte in the sample

An analysis in which a sample's chemical or characterization analysis same

physical properties are evaluated is called:

Linearity can be assessed using any of the

following figures of merit, EXCEPT: Coefficient of variationsame

The alternative analytical procedure should f

be more susceptible to matrix effects than the
original procedure.

Which level of precision is not required in the Sys. suit

validation of analytical methods?

Less prone to operator error A

A drug which is polar will most likely be Excreted?? ou?

(absorbed/excreted) Answer

A drug which is unionized will most Absorbed

likely be (absorbed/excreted)
Nitrofurantoin is toxic due to its capacity to
produce reactive oxygen species. The toxicity
of nitrofurantoin is desired and intentional.
Both are t? Toxic ata siya para ma disrupt
yung dna ng mga pathogens?
Hindi kaya 1st statement is true? Ito na lang
akin Kasi may nabasa ako hindi sya desired
AYYKJAHDKJDH

Carboxyl-abundant drugs will most Stomach?? Same tot

likely be absorbed in the
(stomach/small intestine)
Alkylating agents interact with the guanine of cobalent
DNA strands using which forces?

Intercalating agents interact with the london

nitrogenous bases of the DNA strand using
which forces?

An acidic drug in a highly acidic environment Abs?? same

will most likely be (absorbed/not absorbed)
______
by the body in that environment.

A drug which has a higher log P value will Excreted ba? Kasi kapag above 5 absrobed
most likely be (absorbed/excreted ata absorbed ata nga samee

A basic drug in a highly acidic environment Not abs?? ou?

will most likely be (absorbed/not absorbed)
by the body in that
___

environmen
PCOG LEC QUIZ 2

Which can be used in toothpastes and ointments? Xanthan

Judging from the name, altritol is a product of reduction of a sugar

Which of the following seed gums is a source of Plantago ovata

ispaghula husk

Which of the following has a powerful role in altering the Heparin

coagulation cascade?

The process of diastatic fermentation may give rise to Maltose

which carbohydrate?
Which of the following is/are the soluble form(s)? Pectin only

Algin marine

Which enzyme facilitates formation of 1,6 glycosidic branching enzyme

bonds in starch?

mannose

Scientific source of glucitol Sorbus aucuparia

Which of the following is not a source of gum? Linum usitatissimum

Astragalus gummifer Plant exudate

The glycosidic bond for lactose is _________ while for Beta 1,4 | Alpha 1,4
maltose, it is __________

Which amylase will most likely yield purer maltose? Beta

More abundant Amylopectin

_____ makes up the cell walls of fungi while ____ chitin; pectin
makes up the middle lamella of plants
Which of the following is a potential iodine source? Kelp

In which part of photosynthesis is glucose actually Independent

created?

Which of the following is not a characteristic of a gum? produced by plants without need for stimulation

Which of the following is the resulting liquid from Whey

removal of milk coagulum?

Which can be added to pyroxylin to make it flexible? Castor oil

Which of the following is not a source of sucrose? Hordeum vulgare

Which type of carrageenan is nongelling? lambda

Guaran Seed gum

When sugars are oxidized, what is produced? Sugar acids

Unbranched amylose

Carmellose, a celluose ether, is more commonly known carboxymethylcellulose

as

Which of the following acids contain 4 carbons? tartaric

 alpha

Source of karaya Sterculia urens

Which of the following is a/are plasma expander(s) Two of the choices

Beta-glucosidase

Which can be used for diagnosis of conditions like xylose

Celiac disease?
L-isomer

amylopectin
Less soluble

Alpha 1,4

Which acid has a low solubility product constant, and Oxalic

when deposited in the body can cause acute renal
failure? The salts of this acid also produces itchiness in
some vegetables that are not cooked well
The fat globules after churning of milk may unite and butter
solidify to become

Rum can most likely come from distillation of what? sugarcane

Which starch derivative is a disintegrating agent? Sodium starch glycollate

Which of the following can be considered as a cellulose ether? Caramellose

a.
carmellose

b.
rayon

c.
oxidized cellulose

d.
collodion

The type of drug evaluation which involves the determination of Pharmacological

the biologic activity of the crude drug using animal models.

a.
organoleptic

b.
analytical

c.
pharmacological

d.
physical

e.
chemical

For production of hormones with important roles in blood, pain 3

perception, and lung function, which omega number should the
fatty acid precursors contain?
Which of the following is expected to have the lowest melting Myristic
point?

a.
palmitic acid

b.
oleic acid

c.
stearic acid

d.
myristic acid

This solvent is added to the crude extract to chloroform?samee

preserve and prevent fungal or microbial growth.

a.
methanol
b.
chloroform
c.
benzene
d.
hexane

2 of the choices
Which are considered toxic
metabolites of other existing
poisons and cannot be normally
addressed by the body?
The enzyme that plays a major role in sucrose phosphate
synthase
photosynthetic sucrose synthesis by catalyzing
the rate-limiting step of sucrose biosynthesis from
UDP-glucose and fructose- 6-phosphate.
The fatty acid from ozonolysis of castor oil has use as anti-acne
a.
anti-inflammatory

b.
anti-fungal

c.
anti-acne

d.
sclerosing agent

This solvent is added to the crude extract to preserve and chloro

prevent fungal or microbial growth.

Which of the following can quickly form varnish when exposed to Skdja help
air?
Safflower and linseed =
a. two of the choices????
evening primrose oil

b.
safflower oil

c.
linseed oil

d.
two of the choices

e.
all of the choices

Which of the following will not be subject to All of??

hydrolysis by an alpha-glucosidase?

a.
cellulose
b.
inulin
c.
lactose
d.
two of the choices
e.
all of the choices

Among the choices, he was able to present the most Fluckiger

comprehensive idea of the scope of pharmacognosy.

a.
Dioscorides

b.
Fluckiger

c.
Seydler

d.
Schmidt

Which of the following will not be subject to All ba to Same diko alam
to ahaha
hydrolysis by an alpha-glucosidase

Under whose research was the discovery of Frederick Serturner

morphine, a central constituent in opium?

a.
Frederick Serturner
b.
Alexander Fleming
c.
Pierre Pelletier
d.
Youyou Tu

Among the choices, he was able to present the most Fluckiger

comprehensive idea of the scope of pharmacognosy.

The new name of family Umbelliferae apiaceae

Which is a metabolite that, in high levels, can
lead to cataracts and necrosis of the foot?

a.
ethanol
b.
lactic acid
c.
formic acid
d.
sorbitol

This substance is added to collodion to impart flexibility. 3% castor oil

Match the following omega-numbers with their Alpha linoeic- 3

Delta-linoeic - 6
examples Oleic- 9
Palmitoleic - 7

Which of the following can quickly form varnish when exposed to Two of the cho
air?

The specific plant acid which serves as precursor of amino acids Shikimic
and aromatic compounds.

Which of the following can be considered a structural Two of the choices

carbohydrate - that is, a composition of structures that gives
cells their shape?

The alpha 1,4 glycosidic bond is found in the amylose

following carbohydrates except:

Under whose research was the discovery of serturner

morphine, a central constituent in opium?
The alpha 1,4 glycosidic bond is found in the following
carbohydrates except: trehalose
Which is a metabolite that, in high levels, can lead Sorbitol??? Ou ata
to cataracts and necrosis of the foot?

Which of the following have an expected iodine Two of the choices

value within 100-120?
This substance is added to collodion to impart flexibility. 3% castor

Most popularly used for its off-label use, which is for termination dinoprost
of pregnancy instead of its marketed use

What process leads to formation of trans-fats? hydrogenation

Which of the following plant parts are most oils extracted from? Seeds ba toh?

Which of the given choices is the longest saturated fatty acid? Thank u

Which of the given choices is the longest saturated fatty acid? myristic

Which of the following is supposed to refuse giving a silver Trehalose

mirror in the Tollens test?

Has a delta code of 20 : 5 (Δ5,8,11,14,17) eico

Last step in production of crude drug garbling

Building block for fatty acid synthesis Malonyl coa

Which of the following is supposed to refuse fructose

giving a silver mirror in the Tollens test?
 ALPHA 1-4? Same tot

Help omg diko din gets to ahhaha

Building block for sterol synthesis

Mevalonate pathway yields Fatty acids (di ba
terpenoids??) ou
terpenoids and sterols

Bodybuilders would likely get their protein shake leftover fluid after cheese
production
from the remains of extracts from which source?
 Same tayoo

Normal isomerism of double bonds in fatty acids cis

MIDTERMS orgmed quiz1 NKDJF:sjDKFJKFNSJ

The pioneer of antisepsis prior to surgery is Joseph Lister

the germicidal agent found in arsphenamine was Answer Compound 606 baaa
. The use of this agent, and other agents like it, was Hindi ba as?..
gradually replaced by safer, more effective anti-infectives

Benzoyl peroxide is helpful as an acne treatment because of keratogenic and keratolytic

its additional

Antiseptics become more desirable when they have low Increases?same to

surface tension, which (increases/decreases) Answer
their spreadability.

is an agent that increases the solubility of iodine in water up Povidone Iodine??

to 10 percent w/v.

The minimum requirement for germicides Selective toxicity?? oo

would be that they exhibit
Answer
, a concept that was popularized by Paul
Ehrlich.
Dichlorobenzyl alcohol is a suitable antiseptic for sore throat Local anesthetic
because of its additional Answer

An increase in the number of carbons of an alcohol Hydrophilic?? Di ba lipo?? May

increases its effectiveness since it makes the alcohol more naalala ako na kapag lipo
Choices: hydro or lipophilic nahihirapan magpenetrate ata
aklshd di ako sure okiokii
thankuu ma UY DI AKO SURE
KASI KSJHDSK

EtO exposure indicator stickers turn to blue

Answer
once sufficient gas has reached the medical
device being sterilized.
The higher the phenol coefficient, the (more/less) Answer more
potent the germicide.