Ja R a MD MPH

less common than acute

• Fib i ca cifica i f a c ea
• D e ec e b f ac e a c ea i i
• Alcohol i ad C ic fibro i i chi d e
• M ca e f a c ea i i a e ec e i e ga e
• A c h a d c ic fib i ec e ac e a c ea i i
• CT ca c a ic fi di g i ca cified a c ea

calcium
deposition in
the pancreas

He e h ff Wi i edia
• Ch ic abdominal pain
• Ma a a d a e hallmark of the condition
• Ma be e af e ea fea f ea i g a d eigh
• A a e i a e
• Ma be i d e e a ed a they are not extremelyelevated
unlike in acutepancreatitis
• Fib i a ead f d ci fe e
• Ra e c ica i
2
the pancreas has been
• S e ic ei h b i digested such that
there are Not enough
• Pa c ea ic i fficie c cells to produce high
levels of amylase
lipase
 TREATMENT
takes away the blood
splenectomy drainingfrom the spleen
relieve the engorgement
Re i ga ric Lef Ga ic Vei of the short gastric
hens
arice ia c a ei
e g ge e f
h ga ic ei the portal hen drains blood
from the stomach the
connections between the spleen
splenic 1 the intestines
left gastricmen
Wen S e ic
Vei
S e i Me e e ic Vei
Ke Fi di g I fe i Me e e ic Vei
Il
E a ged ee
Ga ic a ice
lead to upper a I bleeds the pancreas runs
below the splenic
hen
portal hen inflammation due to
this will lead to the development chronic pancreatitis
of Varcies in the stomach can involve the splenic
µ hen which leads to
thrombosis
theobstruction will lead to the didation thrombosis will 2
of collateral between the splenic I obstruct the drainage
G f g C f

2
lose the exocrine
endocrine functions of
• Re f ch ic a c ea i i the pancreas due to
destruction of the tissue
• Fa malab orp ion a d ea orrhea
no enzymes to absorbfats fat in poop
• Fa ol ble i amin deficiencie
• Diabe e fi i
 a
chronicpancreatitis is a
risk factor for pancreatic
cancer
• Ade ca ci a
• M ec a head f a c ea
this is where bile drains into the
duodenum
i most pancreatic canoes will
obstruct the drainage of
bile
this will lead to jaundice

HEAD
TALL

Wikipedia P blic Domain

• Ve g i
• U a e a a ic a e e ai
• M a ie die f hei ca ce
• ea i a de ii e
• ea i a de ega i e
• Of e ca e ag e abd i a ai eigh
• C a ic e e a i i painle ja ndice
• Bi e f i b c ed
• N ai d e ab e ce f ab b ci i fa ai
• S g h f g ad a ead a dice
• Ma ee he ig f a c ea ic bi ia b ci
• Da i e
• Ca c ed
• S ea hea

Ja e Hei a MD Wi i edia
• C a ic h ica e a fi di g f a c ea ic ca ce
• E a ged non ender ga b adde ja ndice
d d d
due to obstructed due to obstructed
bite flow the gall bladder
is NET Inflamed biliaryflow

Wikipedia P blic Domain

 • C a ic fi di g f a c ea ic ca ce
come
occursbelow the skin N causes thrombosis inflammation of hens
goes in • Migra or z perficial hrombophlebi i
different
locations
on the • Mig a c e g e i diffe e ca i
body • S e ficia Be i
• Th b h ebi i Th b i i fa ai f ei
• Red e a d i d a i i ha ig a e
• D e h e c ag ab e ae
Ri Fac

• Age ea d
S ronge Ri k Fac or
• S i g
• Diabe e
• Ch ic a c ea i i O ea
• NOT g a cia ed i h a c h Alcoholic do Not
• S die ha e h i ed fi di g feigeranisEF
pancreatic cancer
• S e da a ha hea d i i g da i c ea e i UNLESS theydevelop
chronic pancreatitis
first
2
BIT there is no direct
relationship between
alcohol the risk of
pancreatic cancer

Ga S e a A ocia ion of Alcohol In ake Wi h Pancrea ic Cancer Mor ali in Ne er

Smoker A ch I e Med
 associated with pancreatic
cancer codefor
• BRCA BRCA ge e DNA e ai ei
• Ge e a i a cia ed i h b ea a ia ca ce
• BRCA m a ion a a cia ed i h a c ea ic CA
• E ecia ea g A hkena i Je 2
mutation is common
amongst this population

J h Wi i edia
Ri Fac

• Af ica A e ica i

F eeS c Ph bi P b ic D ai
T Ma e

• CA
• Ca ce a cia ed a ige
• S ecifici
• Se i i i a be ega i e i a e
• N ef f diag i sensitivity specificity are NOT high
• Ca be f ed af e ea enough
e
2
• CEA If the level continues to rise
carcinoembyonic toes it suggests the malignancy
• Ca be antigen
e e a ed i a c ea is reoccurring
ic ca ce
• P e ii i ecifici
• La ge e aced b CA
Ge e ic

• K RAS ge e ch e
• See i f a c ea ic ca ce
• M f e e a ed ge e i a c ea ic ca ce
• A a f ade a ca ci a e e ce f c ca ce
• SMAD ge e ch e
• T e ge e
• I ac i a ed i f a c ea ic ca ce
T ea e

• Che he a
• Radia i
• S ge
• C a ic ced e i he Whi e ced e pancreatoowadenectomy
• Pa c ea d de ec
 Afterremoval the pancreas is
directy hooked to port
the small bowl
of
the bile ductstomach are
Ca ce Re ea ch UK AND
connected to the small bowl