JABATAN FARMASI

HOSPITAL SULTANAH NUR ZAHIRAH

 Patron
Dr Mohd Salleh bin Mat Jusoh
Hospital Director, HSNZ

Advisors
Puan Zuhaini binti Mukrim
Head of Pharmacy Department, HSNZ

Puan Fatimah Suliana binti Samah

Head of Section, Pharmacotherapy Service, HSNZ

Main Editorial Committees External Reviewer

Puan Teoh Soo Fen,
Dr Nor Zubaidah binti Kadir
Paediatric Pharmacist, HSNZ
Neonatologist, HSNZ
Cik Noor Shukriah binti Hassan,
Puan Muhafizah binti Jusoh
Paediatric Pharmacist, HSNZ
Senior Pharmacist, HSNZ
Encik Toh Yi Siang,
Puan Maznuraini binti Zainuddin
Paediatric Pharmacist, HSNZ
Senior Pharmacist, HSNZ
Puan Nur Liyana binti Mohd Fozi,
Cik Siti Nuraidah binti Mamat,
Paediatric Pharmacist, HSNZ
ICU Pharmacist, HSNZ
Cik Saidatul Aqilah binti Hashim@ Abdullah,
Paediatric Pharmacist, HSNZ

Puan Nur Azyyati binti Ali,

Paediatric Pharmacist, HSNZ

Cik Tok Swee Tee,

Paediatric Pharmacist, HSNZ

Illustrator
Cik Aimi Husna binti Ali
Provisionally Registered Pharmacist, HSNZ

Cik Wajihah binti Mahmood

Provisionally Registered Pharmacist, HSNZ
HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Current Gestational Age (CGA) Day of Life Dose
0 to 7 days 14 mg/kg/dose q48hr
29 weeks or less 8 to 28 days 12 mg/kg/dose q36hr
> 29 days 12 mg/kg/dose q24hr
0 to 7 days 12 mg/kg/dose q36hr
30 to 34 weeks
> 8 days 12 mg/kg/dose q24hr
>35 weeks All 12 mg/kg/dose q24hr
Dose adjustment based on TDM recommendation
Amikacin
IV
250 mg/mL Inj TDM SAMPLING TIME
Pre dose: Just before / within 30 minutes before the 3rd dose
Post dose: 30 minutes after complete infusion of 3rd dose

*IMPORTANT NOTE
To start Amikacin after completed Gentamicin course.
Example:
If patient was on maintenance dose Gentamicin 36 hourly, kindly prescribe
Amikacin 36 hours after last dose of Gentamicin
A Infection due to susceptible organism:
N 1st week of life: 50 mg/kg BD
T Ampicillin
2 to 4 weeks of life: 50 mg/kg QID
I IV
500 mg/vial Inj
Group B Streptococcus (GBS) Meningitis:
B 1st week of life: 200 to 300 mg/kg/day every 8 hours
I > 1 week of life: 300 mg/kg/day every 6 hours
O Ampicillin + Sulbactam 1st week of life: 50 mg/kg Ampicillin BD
IV
1000 mg + 500 mg/vial Inj; > 1 week of life: 50mg/kg Ampicillin QID
T 375 mg Sultamicillin Caplet;
I 250 mg Sultamicillin/5 mL Susp
PO 25 mg/kg Sultamicillin BD
C For treatment of bacteraemia caused by susceptible organism:
100,000 IU/kg BD

Benzyl Penicillin Meningitis, Suspected or Confirmed GBS infection:

5 MIU (3 gm)/vial Inj; IV 100,000 IU/kg BD to QID
1 MIU (600 mg)/vial Inj
Congenital Syphilis:
50,000 IU/kg/dose BD first 7 days then TDS for total of 10 days if CSF
normal OR 14 days if CSF abnormal
Sepsis (infection other than meningitis):
< 2kg: 50 mg/kg BD
> 2kg: 50 mg/kg TDS
Cefotaxime
IV
1 gm/vial Inj
Meningitis:
1st weeks of life: 50 mg/kg TDS [Max: 150 mg/kg/day]
2 to 4 weeks plus of life: 50 mg/kg QID [Max: 200 mg/kg/day]
Ceftazidime 1st week of life: 25 to 50 mg/kg BD
1 gm/vial Inj; IV 2 to 4 weeks of life: 25 to 50 mg/kg TDS
2 gm/vial Inj > 4 weeks: 50 mg/kg QID

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Other infection: 10 mg/kg BD
Ciprofloxacin IV
Cystic Fibrosis/Severe infection: 10 mg/kg TDS
100 mg/50 mL vial Inj;
250 mg Tab Other infection: 10 to 15 mg/kg BD
PO
Cystic Fibrosis/Severe infection: 20 mg/kg BD
Pre-term < 1 week: 5 mg/kg BD
Pre-term > 1 week; Term <1 week: 5 mg/kg TDS
Clindamycin IV Term > 1 week: 7.5 mg/kg TDS
300 mg/vial Inj; > 28 days: 10 mg/kg TDS
300 mg Cap
Severe infection, > 28 days: 20 mg/kg TDS
PO 6 mg/kg QID
Cloxacillin 1st week of life: 50 mg/kg BD
500 mg/vial Inj; IV 2 to 4 weeks of life: 50 mg/kg TDS
250 mg Cap; > 4 weeks of life: 50 mg/kg QID
500 mg Cap;
125 mg/5 mL Susp PO 15 mg/kg QID
Erythromycin IV Prokinetic ONLY: 2mg/kg TDS; infusion at least 1 hour
Salt Ethylsuccinate - 400 mg
Tab; Atypical infection: 12.5 mg/kg QID
A 200 mg/5 mL Susp PO Pertussis: 12.5 mg/kg QID
N Salt Lactobionate – 500mg Inj Prokinetic: 2 mg/kg TDS
T Ethambutol
PO Tuberculosis (intensive): 15 to 25 mg/kg OD
100 mg/mL Susp
I > 2.5 kg: 5 mg/kg OD
B 1.2 to 2.5 kg: 5 mg/kg 36 hourly
I < 1.2 kg: 5 mg/kg 48 hourly
Gentamicin Dose adjustment based on TDM recommendation
O 80 mg/vial Inj
IV
T TDM SAMPLING TIME
I Pre dose: Just before / within 30 minutes before the 3rd dose
Post dose: 30 minutes after complete infusion of 3rd dose
C
1st week of life: 25 mg/kg Imipenem BD
Imipenem + Cilastatin
IV 2 to 4 weeks of life: 25 mg/kg Imipenem TDS
500 mg + 500 mg/vial Inj
> 4 weeks of life: 25 mg/kg Imipenem TDS, up to QID
Isoniazid
PO Tuberculosis (intensive): 10 to 15 mg/kg OD
10 mg/mL Susp
Meropenem 1st week of life: 20 to 40 mg/kg BD
1 gm/vial Inj; IV
> 1 week of life: 20 to 40 mg/kg TDS
500 mg/vial Inj
Loading dose: 15 mg/kg STAT;

Maintenance dose:
Metronidazole < 4 weeks of life: 7.5 mg/kg BD
500 mg/vial Inj;
IV/PO > 4 weeks of life: 7.5 mg/kg TDS
200 mg Tab;
200 mg/5 mL Susp
1st maintenance dose after loading dose
Term: start 24 hours after loading dose
< 2kg: start 48 hours after loading dose
Phenoxymethyl Penicillin
PO 12.5 mg/kg BD to QID [Max 62.5 mg/dose]
125 mg Tab
HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM
HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Piperacillin + Tazobactam ≤ 6 months: 100 mg/kg Piperacillin TDS
IV
4 gm + 500 mg/vial Inj > 6 months: 100 mg/kg Piperacillin TDS to QID
Pyrazinamide
PO Tuberculosis (intensive): 30 to 40 mg/kg OD
100 mg/mL Susp
Rifampicin Tuberculosis (intensive): 10 to 20 mg/kg OD
PO
25 mg/mL Susp Adjunct therapy to Staphylococcal infection: 10 mg/kg BD
A
Pneumocystis Pneumonia (PCP): 5 mg/kg Trimethoprim BD to TDS
N Sulphamethoxazole + IV
Infection due to susceptible organism: 4 mg/kg Trimethoprim BD
T Trimethoprim Pneumocystis Pneumonia (PCP) prophylaxis:
400 mg + 80 mg/vial Inj;
B 400 mg + 80 mg Susp
5 mg/kg Trimethoprim 3x/week (Drug Doses by Frank Shann);
OR 5 to 10 mg/kg OD OR 3x/week (AIDS info)
I PO
O Trimethoprim
50 mg/5 mL Susp Urinary Tract Infection: 4 mg/kg Trimethoprim BD [Max: 300 mg/day]
T Urinary Tract Infection (prophylaxis): 2 mg/kg Trimethoprim ON
I Infection due to susceptible organism:
10 mg/kg QID
C Dose adjustment based on TDM recommendation
IV
Vancomycin
500 mg/vial Inj TDM SAMPLING TIME
Pre dose: Just before / within 30 minutes before 4 th dose (or per pharmacist)
Clostridium difficile infection:
PO
10 mg/kg QID
Aciclovir/Acyclovir Varicella Zoster: 15 mg/kg/dose TDS for 5 days (7 to 10 days if vesicle
A 250 mg/vial Inj; IV developed)
N 200 mg/5 mL Syrup Herpes infections: 10 mg/kg TDS for 2 weeks
T Dose Duration
Infections CGA (weeks) Frequency
I Oseltamivir (mg) (Days)
75 mg Cap; PO < 38 1 mg/kg
-
60 mg/5 mL Susp H1N1 38 to 40 1.5 mg/kg BD 5
V > 40 3 mg/kg
I
< 2 kg: 8 mg/dose
R Nevirapine
PO > 2 kg: 12 mg/dose
50 mg/5 mL Susp
A For 3 doses: 1st at birth; 2nd at 48 hours after 1st dose; 3rd at 96 hours after 2nd dose
L Zidovudine
PO 4 mg/kg/dose BD
10 mg/mL Syr
A 0.5 mg/kg OD with test dose (D1), 0.75 mg/kg OD (D2), 1.0 mg/kg OD (D3)
[Max: 1.5 mg/kg OD]
N Amphotericin
IV
T 50 mg/vial Inj
Test dose:
I 0.1 mg/kg STAT [Max: 1 mg/dose]
- < 14 days: 12 mg/kg 72 hourly
Fluconazole 15 to 28 days: 12 mg/kg 48 hourly
F 100 mg/vial Inj; IV
> 28 days: LD: 6 mg/kg STAT; MD: 3 mg/kg OD
U 100 mg Cap
Severe infection: 12 mg/kg OD [Max: 800 mg/dose]
N
≤ 12 months
G Nystatin PO
Prophylaxis 50,000 IU TDS
A 500,000 IU/5 mL Susp
Treatment 100,000 IU QID
L
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HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
A Congenital Toxoplasmosis:

N CDC
T Pyrimethamine
1 mg/kg/dose BD x 2 days then,
I Day 3 to 2 months (or 6 months if symptomatic) 1 mg/kg/day OD then
- 1 mg/kg/day 3 times per week
Pyrimethamine PLUS
P 25 mg Tab PO Clindamycin 5 to 7.5 mg/kg/dose TDS to QID x 12 months
A (Can be cut into half) PLUS
Folinic Acid 10 mg 3 times per week x 12 months
R
A NAG 2019
Pyrimethamine
S 1 mg/kg/day OD x 2/12 then 0.5 mg/kg/day OD x 10 months
I PLUS
Clindamycin 5 to 7.5 mg/kg/dose TDS to QID x 12 months
T
PLUS
E Folinic Acid 50 mg q7days x 12 months
Glycerin Enema (RAVIN®)
PR 0.5 to 1 mL up to BD
20 mL/tube
Metoclopramide
10 mg/vial Inj; IV/PO 0.1 to 0.3 mg/kg TDS
G 1 mg/mL Syrup
Omeprazole IV 1 mg/kg BD
I 40 mg/vial Inj;
T 2 mg/mL Susp PO 0.4 to 0.8 mg/kg BD
Pantoprazole
IV 1 mg/kg OD to BD
40 mg/vial Inj
Ranitidine
IV 1 mg/kg TDS
50 mg/vial Inj
Alphacalcidol Drops Osteopenia in Prematurity:
PO
2 mcg/mL (0.1 mcg = 1 drop) 0.1 mcg OD, increase by 0.1 mcg OD if not respond well [Max: 1 mcg/day]
Ferric Ammonium Citrate
S Mixture Treatment: 6 mg/kg elemental iron OD
PO
U 400 mg/5 mL Prophylaxis: 2 mg/kg elemental iron OD
P (80 mg elemental iron/mL) Mist
Folate/Folic Acid Suspension
P 1 mg/mL Susp
PO 0.1 mg OD
L Multivitamin
PO Term: 1 mL OD
E Multivitamin Elixir
Infant/Children with disease that associated with Vitamin D deficiency
M (eg: Rickets, Osteogenesis Imperfecta, Cystic Fibrosis, Chronic Liver
E Multivitamin Infant Drop
PO Disease and etc.)
Appeton® 400 IU Vitamin D
N Prem: 0.5 mL (< 1 kg) OD; 1 mL (≥ 1 kg) OD
T Post-KASAI: may up to 3 mL OD
Seizure: 50 mg BD OR 100 mg OD
S Pyridoxine Isoniazid induced Neuropathy: 5 to 10 mg OD
PO
10 mg Tab Behavioural effect due to Levetiracetam: 100 to 200 mg/day
[Max: 6 mg/kg/day]
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HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Osteopenia in Prematurity:
Sodium Acid Phosphate 1 to 2 mmol/kg/day in 2 divided doses
16 mmol/20 mL Tab PO May start Sodium Acid Phosphate if Phosphate < 1.8 mmol/L AND
(0.8 mmol/mL) ALP > 500 IU/L
Target Phosphate: 1.8 to 2.9 mmol/L; Target Calcium: 2 to 2.75 mmol/L
SC/IM Central Diabetes Insipidus:
Desmopressin /IV 0.025 mcg/kg 1 to 2 doses/day [Max: 4 mcg/dose]
4 mcg/mL Inj < 2 years: 10 mcg BD to TDS
0.1 mg/tab PO 2 to 12 years: 50 mcg BD to TDS
> 12 years: 50 to 100 mcg BD to TDS
Post Extubation Stridor:
LD: 0.6 mg/kg STAT;
MD: 0.25 mg/kg TDS to QID
IV
Meningitis:
0.15 mg/kg QID x 4/7 OR 0.4 mg/kg BD x 2/7
(Given before OR with the first dose of antibiotic)
Post Extubation Stridor:
MD: 0.25 mg/kg TDS to QID

E DART THERAPY:
Dexamethasone Low Dose (DART) protocol
N 8 mg/vial Inj;
0.075 mg/kg/dose 12 hourly for 3 days then,
D 4 mg Tab;
0.5 mg/mL Susp 0.05 mg/kg/dose 12 hourly for 3 days then,
O 0.025 mg/kg/dose 12 hourly for 2 days then,
C PO
0.01 mg/kg/dose 12 hourly for 2 days then stop.
R Total cumulative dose: 0.89 mg/kg
I High Dose (DART) protocol
N 0.25 mg/kg/dose 12 hourly for 3 days then,
E 0.15 mg/kg/dose 12 hourly for 3 days then,
0.1 mg/kg/dose 12 hourly for 3 days then,
0.05 mg/kg/dose 12 hourly for 3 days then,
0.025 mg/kg/dose 12 hourly for 6 days then stop.
Total cumulative dose: 3.6 mg/kg
Fludrocortisone
PO Initially, 50 to 100 mcg OD OR 150 mcg/m2 OD [Max: 300 mcg/dose]
0.1 mg Tab
Hypoglycaemia despite glucose delivery rate of > 12 mg/kg/min:
Hydrocortisone 1 to 2 mg/kg/dose, up to 4 mg/kg/dose BD to TDS, 1 to 2 days
IV
100 mg/vial Inj;
10 mg Tab; Shock/PPHN/Bronchospasm: 4 mg/kg QID
2 mg/mL Susp Congenital Adrenal Hyperplasia (CAH):
PO
10 to 15 mg/m2/day in 3 divided doses (as per physician)
If glucose delivery > 8 to 10 mg/kg/min and Hypoglycaemia persist:
Glucagon IV/IM
0.5 to 1 mg STAT (IV, IM, SC) then 5 to 10 mcg/kg/hr in IDM cases
(Lyophilised) 1mg/mL vial Inj /SC
*IDM: Infant of Diabetic Mother

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HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Dose
Age
(mcg/kg/dose, daily)
0 to 3 months 10 to 15
Levothyroxine
3 to 6 months 8 to 10
100 mcg Tab; PO
50 mcg Tab
6 to 12 months 6 to 8
Can be given at different doses on alternate days
(e.g.: 50 mcg on even days AND 75 mcg on odd days to give average dose
of 62.5 mcg/day) [Max: 200 mcg/day]
Prednisolone
PO 1 mg/kg OD
5 mg Tab
R Apnoea in Prematurity:
E Caffeine Citrate
PO
LD: 20 mg/kg STAT
20 mg/mL Syrup MD: 5 mg/kg OD, may increase to 7.5 mg/kg OD, UP TO 34 weeks of life
S
[Max 10 mg/kg OD]
P
I
Fluticasone Propionate Bronchopulmonary Dysplasia (BPD)/ Chronic Lung Disease (CLD):
R MDI 125 mcg/puff
INHAL.
125 to 250 mcg BD
A
T
O Bronchopulmonary Dysplasia (BPD)/ Chronic Lung Disease (CLD):
Salbutamol
INHAL. 200 mcg PRN
R MDI 100 mcg/puff;
Exacerbation: 400 to 600 mcg
Y
Captopril
PO 0.1 mg/kg TDS [Max: 6 mg/kg/day in 3 to 4 divided doses]
1 mg/mL Solution
Clopidogrel
PO 0.2 mg/kg OD
5 mg/mL Susp
C Digoxin 15 mcg/kg STAT.
IV/PO
A 250 mcg/mL Inj; After 6 hours, 5 mcg/kg then start MD 3 to 5 mcg/kg BD
R Frusemide/Furosemide
20 mg/vial Inj; IV/PO 0.5 to 2 mg/kg BD to QID [Max: 6 mg/kg/day]
D 10 mg/mL Syrup
I Hydrochlorothiazide PO 1 to 2 mg/kg BD
O 5 mg/mL Susp
V Central Diabetes Insipidus:
3 mg/kg/day OD
A Nifedipine
S PO 0.5 to 1 mg/kg BD to TDS
4 mg/mL Susp
C Indications Dose
U Anti-failure 0.2 to 1.5 mg/kg TDS to QID
Propranolol DAY 1: 0.5 mg/kg/day in 3 divided doses for 1 day;
L 40 mg Tab;
Haemangioma DAY 2: 1.0 mg/kg/day in 3 divided doses for 1 day;
A 1 mg/mL Syrup
Dermatology DAY 3: 1.5 mg/kg/day in 3 divided doses for 1 day;
R MD: 2.0 mg/kg/day in 3 divided doses
Spironolactone < 3 kg: 1 mg/kg OD to BD
25 mg Tab; PO
> 3 kg: 3.125 to 6.25 mg OD to BD
2.5 mg/mL Syrup

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HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Baclofen 0.2 mg/kg TDS
PO
10 mg/mL May increase every 3 days up to 1 mg/kg TDS if required
Levetiracetam LD: 40 mg/kg over 10 mins
IV
250 mg/vial Inj; MD: 20 mg/kg BD [Max: 60 mg/kg/day in 2 to 3 divided doses]
100 mg/mL Solution PO 10 mg/kg BD [Max: 60 mg/kg/day in 2 to 3 divided doses]
Bolus: 0.1 to 0.2 mg/kg over at least 2 to 5 min
Midazolam Infusion:
15 mg/vial Inj; IV
Sedation: 1 to 4 mcg/kg/min
5 mg/vial Inj
Seizure:  4 mcg/kg/min
LD: 20 mg/kg [Max: 40 mg/kg/day; 1.5 gm/dose] over 30 mins
MD: 4 to 8 mg/kg/day in 2 to 3 divided doses [Max: 600 mg/day]
Dose adjustment based on TDM recommendation

TDM SAMPLING TIME

After loading dose:
IV
Post LD: 4 to 6 hours after complete infusion of loading dose
Pre dose: Just before the next maintenance dose
Phenytoin
Without loading dose:
100 mg/vial Inj;
N 100 mg Cap;
7 to 10 days (after initiation or a change in regimen)
Pre dose: Just before the next maintenance dose
E 30 mg Cap
4 to 8 mg/kg/day in 2 to 3 divided doses [Max: 600 mg/day]
U Dose adjustment based on TDM recommendation
R
O TDM SAMPLING TIME
PO After loading dose:
L Post LD: 24 hours after administration of oral loading dose
O Pre dose: Just before the next maintenance dose
G Not recommended in patient on Ryles Tube
Y LD: 20 mg/kg [Max: 40 mg/kg/day] over 30 mins
MD: 2.5 mg/kg BD
Dose adjustment based on TDM recommendation

TDM SAMPLING TIME

IV After loading dose:
Post LD: 2 – 3 hours after complete infusion of loading dose
Phenobarbitone
Pre dose: Just before the next maintenance dose
200 mg/vial Inj;
30 mg Tab;
Without loading dose:
10 mg/mL Susp
2 to 4 weeks (after initiation or a change in regimen)
Pre dose: Just before the next maintenance dose
MD: 2.5 mg/kg BD
Dose adjustment based on TDM recommendation
PO
TDM SAMPLING TIME
Pre dose: Just before the next maintenance dose
Topiramate LD: 0.5 to 1.0 mg/kg/day, then increase every 2 weeks by 1 mg/kg/day in 2
25 mg Tab; PO divided doses
50 mg Tab MD: 5 to 9 mg/kg/day

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HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Hyponatremia:
Step Method
𝐵𝑊 (𝑘𝑔)𝑥 4 𝑥 (140−𝑁𝑎)
Na DEFICIT (mL Saline) =
1 % 𝑠𝑎𝑙𝑖𝑛𝑒
[Max safe rate: 0.5 mmol/mL/hr]
2 𝑥 𝐵𝑊(𝑘𝑔)
2 INFUSION RATE (mL/hr) =
% 𝑠𝑎𝑙𝑖𝑛𝑒 𝑖𝑛𝑓𝑢𝑠𝑒𝑑

3 HOURS OF INFUSION = 2 x (140 – serum Na)

Example:
SODIUM CORRECTION • Body weight of 0.995 kg, Na: 120 mmol/L.
• Correction using 3% NaCl/500 mL
Sodium Chloride Step Method
3%/500 mL IV Drip; 𝐵𝑊 (𝑘𝑔)𝑥 4 𝑥 (140−𝑁𝑎)
Na deficit (mL Saline) =
0.9%/500 mL IV Drip; % 𝑠𝑎𝑙𝑖𝑛𝑒
0.995𝑘𝑔 𝑥 4 𝑥 (140−120)
5.85% Mixt =
E 3%
= 26. 53 mL 3% Saline required
L 0.9% = 0.152 mmol Na/mL 1
E 5.85% (6%) = 1mmol Na/mL
Since maximum sodium increment allowance is 10 mmol, thus
3% = 0.513 mmol Na/mL
C 20% = 3.4 mmol Na/mL =
0.995𝑘𝑔 𝑥 4 𝑥 10
3%
T IV
=12.72 mL 3% NaCl required
1 g NaCl =17.1 mmol/L Na 2 𝑥 𝐵𝑊(𝑘𝑔)
R INFUSION RATE (mL/hr) =
% 𝑠𝑎𝑙𝑖𝑛𝑒 𝑖𝑛𝑓𝑢𝑠𝑒𝑑
O Max increment allowance: 10
2
L mmol per correction
=
2 𝑥 0.995𝑘𝑔
= 0.663mL /hr
3%
Y Delivery Na = ~ 0.6mL/hr
T Up to 0.5 mmol/kg/hr HOURS OF INFUSION = 2 x (140 – serum Na)
E Max rate of plasma Na 3
Since maximum sodium increment allowance is 10 mmol, thus
increment: Not more than 12 = 2 x 10 = 20 hours
mmol/L in 24hr (practice only 8
Thus, to run 3% NaCl at 0.6 mL/hr for 20 hr
mmol/L/d)

To counter check:
➢ 0.6 mL/hr x 20 hr = 12 mL of 3% NaCl required for transfusion
➢ 12 mL of 3% NaCl = 6 mmol of Na+ (does not exceed max allow
increment of 10 mmol)
➢ 0.6 mL/hr = 0.3 mmol/hr (does not exceed max safe rate 0.5
mmol/mL/hr)

Let say, to run 3% NaCl 0.6mL/hr for 40 hr = 24 mL

➢ 24 mL of 3% NaCl = 12 mmol (will exceed maximum increment
allowance of 10 mmol per correction)
Hyponatremia:
PO Initially, 0.5 to 1 mL every 3 hours (each feeding), QID (alternate feeding),
TDS/BD/OD [adjust accordingly Sodium level]

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HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Hypocalcaemia:
CALCIUM CORRECTION 0.5 mL/kg STAT
Ref:
Calcium Gluconate 10% in 10 Term baby: Corrected Ca < 2.0 mmol/L or Ionised Ca < 1.2
mL Preterm baby: Corrected Ca < 1.75 mmol/L or Ionised Ca < 1.2
IV
2.2 mmol/ 10 mL amp =
89 mg elemental Ca /10 mL *If prolong hypoglycaemia unresolved by STAT dose Ca Gluconate may consider
(0.22 mmol/L /mL= 8.9 mg regular Ca
elemental Ca /mL) *Preferably run through central line, if run through peripheral line may cause
thrombophlebitis

CALCIUM CORRECTION
Hypocalcaemia:
Calcium Carbonate 500 mg Initial dose: 50 mg/dose QID (20 mg elemental Ca/ dose QID),
PO
Tab up to 20 to 80 mg/kg/day elemental calcium in 2 to 4 divided doses
500 mg = 200 mg elemental Ca Ref: Corrected Ca < 2.0 mmol/L or Ionised Ca < 1.2
= 5 mmol/L Ca
MAGNESIUM CORRECTION
Hypomagnesemia:
Magnesium Sulphate IV 0.2 mL/kg STAT
2.47 g / 5 mL amp Ref: Mg < 0.7 mmol/L
10 mmol Mg ion / 5 mL

POTASSIUM CORRECTION

Potassium Chloride Inj. Hypokalaemia:

13.4 mmol/ 1 gm/10 mL amp Daily K requirement = 1 mmol/kg
125 mg/5 mL Mixt Total K requirement = K deficit + daily K requirement
IV/PO
1 g KCL =13.4 mmol/L K
K deficit (mmol/L) = (Knormal lower limit – Kmeasured) x BW (kg) x 0.4
Inj KCl in IV drip: Ref: K < 3.5 mmol/L, [Max tolerated K in neonate: up to 6 mmol/L
Maintenance 0.5 g/pint
Deficiency 1 g/pint

Hyperkalaemia:
Sodium Polystyrene
PR 0.3 to 1 g/kg STAT (up to QID)
Sulphonate (Resonium)
Ref: K > 6.5 mmol/L

M Hyperammonaemia due to Urea Cycle Defects:

E Anti-hyperammonaemia
T drugs cocktail Loading Dose:
A IV Sodium Benzoate 250 mg/kg
IV Sodium Benzoate IV Sodium Phenylbutyrate 250 mg/kg
B 2 gm / 10 mL amp Inj IV
IV L-Arginine 250 mg/kg
O IV Sodium Phenylbutyrate
[Mix together in D10% to a total volume of 50 mL, infuse over 90 min]
2 gm / 10 mL amp Inj
L IV L-Arginine
I 5 gm / 10 mL amp Inj
Maintenance Dose:
Same dilution as above BUT infuse over 24 hours
C

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) NEONATE COMMON MEDICATION DOSING 2021 – 1st edition 2021

NEONATE COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Chloral Hydrate
PO Initially 10mg/kg TDS to QID, can be up to 50mg/kg QID [Max: 2 g/dose]
200 mg/5mL Mixt.
Hepatitis Immunoglobulin
Prophylaxis of Hepatitis B after Hepatitis B Virus Exposure
100 unit/0.5 mL Inj; IM
100 to 200 unit preferred within 48 hours of exposure OR within 5 days
200 unit/1 mL Inj
Human Albumin 20%: 2 to 5 mL/kg, up to 10 mL/kg
20% vial Inj; IV
5%: 10 to 20 mL/kg/course
5% vial Inj
Severe Jaundice: 0.5 to 1 gm/kg over 2 hours
Dose can be repeated in 12 hours if necessary. If exchange transfusion already
Human Normal indicated, IVIG should be given after ET
Immunoglobulin (IG)
IV
3.0 gm/vial Inj;
Test dose:
2.5 gm/vial Inj
5 mL/hour for 15 mins; then 10 mL/hour for 15 mins; then 15 mL/hour for
M 15 mins; then 20 mL/hour for 15 mins
I Patent Ductus Arteriosus (PDA) Closure
S Day 1 2 3
Ibuprofen
PO 1st Cycle 10 mg/kg STAT 5 mg/kg OD 5 mg/kg OD
C 200 mg Tab
2nd Cycle 20 mg/kg STAT 10 mg/kg OD 10 mg/kg OD
E (Interval between 1st and 2nd cycle: 1 week)
L Patent Ductus Arteriosus (PDA) Closure:
IV
L 15 mg/kg QID x 5 days
A Paracetamol Patent Ductus Arteriosus (PDA) Closure:
100 mg/10mL vial Inj; 15 mg/kg QID x 5 days
N 250 mg/5 mL Susp; PO
E 250 mg/Supp; Antipyretic and Analgesic:
125 mg/Supp 10 mg/kg PRN [Max QID)
O
Antipyretic and Analgesic:
U PR
30 mg/kg PRN [Minimum: 62.5 mg]
S Rocuronium 0.6 to 1.2 mg/kg STAT
IV
10 mg/mL vial Then bolus: 0.1 to 0.2 mg/kg OR infusion: 5 to 15 mcg/kg/min
Ursodeoxycholic Acid
PO 5 to 10 mg/kg BD
250 mg Cap
Persistent Pulmonary Hypertension in the Neonate (PPHN):
1st dose: 0.5 mg/kg then 6 hours later
Sildenafil Citrate 2nd dose: 1.0 mg/kg then 6 hours later
2.5 mg/mL Susp PO 3rd dose: 1.5 mg/kg then 6 hours later
4th dose: 2.0 mg/kg then
MD: 2.0 mg/kg QID
Tapering down by 2.0 mg/kg TDS to BD then OD
Vitamin K
1 mg/mL Inj; IV 0.3 mg/kg OD [Max: 1 mg/dose]
10 mg/mL Inj
REFERENCES
Paediatric Protocol 4th Edition
Drug Doses by Frank Shann 2017 edition
British National Formulary for Children 2019-2020
National Antibiotic Guideline 2019
**p/s: please refer to Frank Shann/ BNF for medication that are not listed here

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

 PAEDIATRIC
COMMON
MEDICATION
D O S I N G IN H S N Z

JABATAN FARMASI
HOSPITAL SULTANAH NUR ZAHIRAH
 Patron
Dr Mohd Salleh bin Mat Jusoh
Hospital Director, HSNZ

Advisors
Puan Zuhaini binti Mukrim
Head of Pharmacy Department, HSNZ

Puan Fatimah Suliana binti Samah

Head of Section, Pharmacotherapy Service, HSNZ

Main Editorial Committees External Reviewer

Puan Teoh Soo Fen,
Dr Noor Ain binti Noor Affendi
Paediatric Pharmacist, HSNZ
Paediatric Respiratory Specialist, HSNZ
Cik Noor Shukriah binti Hassan,
Dr Muhaireen binti Arshad
Paediatric Pharmacist, HSNZ
Paediatrician, HSNZ
Encik Toh Yi Siang,
Puan Muhafizah binti Jusoh
Paediatric Pharmacist, HSNZ
Senior Pharmacist, HSNZ
Puan Nur Liyana binti Mohd Fozi,
Puan Maznuraini binti Zainuddin
Paediatric Pharmacist, HSNZ
Senior Pharmacist, HSNZ
Cik Saidatul Aqilah binti Hashim@ Abdullah,
Cik Siti Nuraidah binti Mamat,
Paediatric Pharmacist, HSNZ
ICU Pharmacist, HSNZ
Puan Nur Azyyati binti Ali,
Paediatric Pharmacist, HSNZ

Cik Tok Swee Tee,

Paediatric Pharmacist, HSNZ

Illustrator
Cik Aimi Husna binti Ali
Provisionally Registered Pharmacist, HSNZ

Cik Wajihah binti Mahmood

Provisionally Registered Pharmacist, HSNZ
HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Amikacin 10 to 15 mg/kg OD, up to 18 mg/kg [Max: 500 mg/dose]
IV
250 mg/mL Inj Dose adjustment based on TDM recommendation
Amoxicillin/Amoxycillin
25 mg/kg TDS, if required may up to 40 mg/kg TDS [Max: 500 mg/dose
250 mg Cap; PO
TDS; Lyme disease: up to 1 g/dose TDS]
125 mg/5 mL Susp.
Amoxicillin + Clavulanic Acid IV 25 to 30 mg/kg Amoxicillin TDS [Max: 1 gm Amoxicillin base/dose]
1000 mg + 200 mg/vial Inj;
500 mg + 125 mg Tab; Tab: 25 mg/kg Amoxicillin TDS
200 mg + 28 mg/5 mL Susp PO
Susp: 25 mg/kg Amoxicillin BD [Max: 500 mg Amoxicillin base/dose]
25 to 50 mg/kg QID
Ampicillin
IV [Max: uncomplicated CAP/UTI: 1 gm/dose; Enterococcal endocarditis/
500 mg/vial Inj
Listeria meningitis: 2 gm/dose]
Ampicillin + Sulbactam IV 25 to 50 mg/kg Ampicillin QID [Max: 2 gm Ampicillin/dose]
1000 mg + 500 mg/vial Inj;
375 mg Sultamicillin Caplet;
PO 25 mg/kg Sultamicillin BD [Max: 750 mg Sultamicillin/dose]
250 mg Sultamicillin/5 mL Susp
15 mg/kg OD (D1), then 7.5 mg/kg OD (D2 to D5);
Azithromycin OR 15 mg/kg OD for 3 days
A PO
250 mg Tab Immunomodulator: 5 mg/kg 3x/week
N [Max: 500 mg/dose]
T Prophylaxis Rheumatic fever (Every 3 to 4 weeks):
Benzathine Penicillin
I IM < 30 kg: 0.6 MIU
2.4 MIU (1.8 gm)/vial Inj
≥ 30 kg: 1.2 MIU
B
Benzyl Penicillin Pharyngitis; Tonsillitis: 25,000 IU/kg QID
I 5 MIU (3 gm)/vial Inj; IV Pneumonia; Rheumatic fever: 50,000 IU/kg QID
O 1 MIU (600 mg)/vial Inj Meningitis: 100,000 IU/kg QID [Max: 4 MIU/dose]
T Cefepime
IV 25 to 50 mg/kg BD to TDS [Max: 2 gm/dose]
1 gm/vial Inj
I Meningitis: 50 mg/kg QID
C Cefotaxime
IV Other infections: 25 to 50 mg/kg TDS, if severe up to 4 to 6 hourly
1 gm/vial Inj
[Max: 2 gm/dose; up to 12 gm/day]
Ceftazidime
1 gm/vial Inj; IV 25 to 50 mg/kg TDS to QID [Max: 2 gm/dose]
2 gm/vial Inj
Meningitis: 50 mg/kg BD
Ceftriaxone Salmonellosis: 50 to 75 mg/kg OD
IV/IM
1 gm/vial Inj Leptospirosis: 100 mg/kg OD
Other infections: 50 mg/kg OD [Max: 2 gm/dose, 4 gm/day]
Cefuroxime
IV 25 to 50 mg/kg TDS [Max: 1.5 gm/dose]
1500 mg/vial Inj;
125 mg Tab;
PO 15 mg/kg BD [Max: 250 mg/dose]
125 mg/5 mL Susp
Cephalexin 12.5 to 25 mg/kg BD to QID [Max: 500 mg/dose]
PO
250 mg Tab UTI prophylaxis: 12.5 mg/kg ON [Max: 125 mg/dose]
Other infection: 10 mg/kg BD
Ciprofloxacin IV
Cystic Fibrosis/Severe infection: 10 mg/kg TDS [Max 400 mg/dose]
100 mg/50 mL vial Inj;
Other infection: 10 to 15 mg/kg BD
250 mg Tab PO
Cystic Fibrosis/Severe infection: 20 mg/kg BD [Max: 750 mg/dose]

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Clindamycin IV 15 to 20 mg/kg TDS to QID [Max: 900 mg/dose]
300 mg/vial Inj;
300 mg Cap PO 6 mg/kg QID
Cloxacillin
500 mg/vial Inj; IV 25 to 50 mg/kg QID, up to 4 hourly [Max: 2 gm/dose]
250 mg Cap;
500 mg Cap; PO 15 to 25 mg/kg QID [Max: 1 gm/dose]
125 mg/5 mL Susp
Complicated Skin and Soft Tissue Infections (cSSTI), Community Acquired
Pneumonia (CAP):
< 2 months: 6 mg/kg TDS
≥ 2 months to < 2 years: 8 mg/kg TDS
≥ 2 years to < 12 years; ≥ 12 years to 18 years;< 33kg: 12 mg/kg TDS [Max:
Ceftaroline Fosamil 400 mg/dose]
IV
600 mg/vial Inj ≥ 12 years to 18 years; ≥ 33kg: 600 mg BD
High Dose
cSSTI confirmed OR suspected to be caused by S. aureus with MIC = 2
mg/L OR 4 mg/L to Ceftaroline:
≥ 2 months to < 2 years: 10 mg/kg TDS
A ≥ 2 years to < 18 years: 12 mg/kg TDS [Max: 600 mg/dose]
N Doxycycline 2 mg/kg BD (D1), then 2 mg/kg OD
PO
100 mg Cap Severe: 2 mg/kg BD [Max: 200 mg/day]
T
IV Prokinetic ONLY: 2 mg/kg TDS; infusion at least 1 hour
I Erythromycin
Atypical pneumonia/infection: 12.5 mg/kg QID
B Salt Ethylsuccinate - 400 mg
Pertussis: 20 mg/kg QID [Max: 400 mg/dose]
Tab;
I 200 mg/5 mL Susp PO Prophylaxis Rheumatic Fever (if allergic to Penicillin): 15 to 20 mg/kg BD
O Salt Lactobionate – 500mg Inj [Max: 800 mg BD]
Prokinetic: 2 mg/kg TDS
T
Ethambutol
I 400 mg Tab; PO Tuberculosis (intensive): 15 to 25 mg/kg OD [Max: 1000 mg/dose]
C 100 mg/mL Susp
Infective Endocarditis: 1 mg/kg TDS
Gentamicin
IV Other infections: 5 mg/kg OD [Max: 360 mg/dose]
80 mg/vial Inj
Dose adjustment based on TDM recommendation
Imipenem + Cilastatin
IV 25 mg/kg Imipenem TDS to QID [Max: 1 gm/dose]
500 mg + 500 mg/vial Inj
Isoniazid
100 mg Tab; PO Tuberculosis (intensive): 10 to 15 mg/kg OD [Max: 300 mg/dose]
10 mg/mL Susp
Linezolid
600 mg Tab; PO 10 mg/kg TDS [Max: 600mg/dose]
20 mg/mL Susp
Meropenem
1 gm/vial Inj; IV 20 to 40 mg/kg TDS [Max: 2 gm/dose]
500 mg/vial Inj
LD: 15 mg/kg STAT;
Metronidazole IV
MD: 7.5 mg/kg TDS [Max: 500 mg/dose]
500 mg/vial Inj;
LD: 15 mg/kg STAT;
200 mg Tab;
200 mg/5 mL Susp PO MD: 7.5 mg/kg TDS [Max: 400 mg/dose]
Clostridium difficile: 10 mg/kg TDS

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
PEADS PROTOCOL 4TH EDITION
Nephrotic Syndrome:
Age
Dose Treatment Prophylaxis
(y.o)
1 to 5 125
6 to 12 250 QID BD
> 12 500

Post Streptococcal Acute Glomerulonephritis (AGN):

Age
Dose Treatment
(y.o)
Phenoxymethyl Penicillin 1 to 5 125
PO QID
125 mg Tab 6 to 12 250
duration: 10 days
> 12 500

Rheumatic Fever:
Weight
Dose Treatment Prophylaxis
A (kg)
< 30 250
N ≥ 30 500
QID 250 mg BD
T FRANK SHANN 2017 EDITION
I Treatment: 10 to 15 mg/kg QID
B Prophylaxis: 10 to 15 mg/kg BD
– round up to nearest strength [Max: 500 mg/dose]
I
O Piperacillin + Tazobactam
≤ 6 months: 100 mg/kg Piperacillin TDS
T IV > 6 months: 100 mg/kg Piperacillin TDS to QID
4 gm + 500 mg/vial Inj
[Max: 4.5 gm/dose]
I Pyrazinamide
C 500 mg Tab; PO Tuberculosis (intensive): 30 to 40 mg/kg OD [Max: 2 gm/dose]
100 mg/mL Susp
Rifampicin
300 mg Cap; Tuberculosis (intensive): 10 to 20 mg/kg OD [Max: 600 mg/dose]
PO
150 mg Cap; Adjunct therapy to Staphylococcal infection: 10 mg/kg BD
25 mg/mL Susp

Sulphamethoxazole + Pneumocystis Pneumonia (PCP): 5 mg/kg Trimethoprim BD to TDS

IV
Trimethoprim Infection due to susceptible organism: 4 mg/kg Trimethoprim BD
400 mg + 80 mg/vial Inj;
Pneumocystis Pneumonia (PCP) prophylaxis:
400 mg + 80 mg Tab
5 mg/kg Trimethoprim 3x/week (Drug Doses by Frank Shann);
400 mg + 80 mg Susp
OR 5 to 10 mg/kg OD OR 3x/week (AIDS info)
PO
Trimethoprim
50 mg/5 mL Susp Urinary Tract Infection: 4 mg/kg Trimethoprim BD [Max: 300 mg/day]
Urinary Tract Infection (prophylaxis): 2 mg/kg Trimethoprim ON
15 to 20 mg/kg BD to QID [Max: 60 mg/kg/day]
IV
Vancomycin Dose adjustment based on TDM recommendation
500 mg/vial Inj Clostridium difficile infection:
PO
10 mg/kg QID [Max: 125 mg/dose QID]

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
2
Cutaneous Herpes: 250 mg/m TDS
IV
Other indication: 500 mg/m2 TDS
Dose Duration
Infections Age Frequency
(mg) (Days)
Aciclovir/Acyclovir
250 mg/vial Inj; 1 to 23 m.o. 100*
A Herpes Simplex
2 to 17 y.o. 200*
5x ≥5
800 mg Tab;
N 200 mg Tab; PO 1 to 23 m.o. 200
T 200 mg/5 mL Syrup Varicella Zoster, 2 to 5 y.o. 400 QID 5
I Herpes Zoster 6 to 11 y.o. 800
- 12 to 17 y.o. 800 5x 7
V *Immunocompromised patient may require higher dose (double dose)

I Dose Duration
Infections Age/Weight Frequency
(mg) (Days)
R < 3 m.o. 12
A < 1 year
3 to 5 m.o. 20
Oseltamivir old
L 75 mg Cap; PO 6 to 11 m.o. 25
60 mg/5 mL Susp H1N1 ≤ 15 kg 30 BD 5
≥ 12 16 to 23 kg 45
months 24 to 40 kg 60
> 40 kg 75
0.5 mg/kg OD with test dose (D1), 0.75 mg/kg OD (D2), 1.0 mg/kg OD (D3)
[Max: 1.5 mg/kg OD]
Amphotericin
IV
50 mg/vial Inj
Test dose:
0.1 mg/kg STAT [Max: 1 mg/dose]
LD: 70 mg/m2 STAT;
Caspofungin
IV MD: 50 mg/m2 OD
70 mg/vial Inj
A [Max: 70 mg/dose]
N Fluconazole
LD: 6 mg/kg STAT; MD: 3 mg/kg OD
100 mg/vial Inj; IV
T 100 mg Cap
Severe infection: 12 mg/kg OD [Max: 800 mg/dose]
I Treatment oropharyngeal candidiasis: 3 to 5 mg/kg OD
- Treatment systemic candidiasis where other antifungal drugs
Itraconazole inappropriate OR ineffective: 5 mg/kg OD
F 10 mg/mL Susp Prophylaxis of deep fungal infection in hematological malignancy patient:
U PO
3 mg/kg OD
N [Max: 200 mg/dose]
G ≤ 12 months > 12 months
Nystatin PO
A 500,000 IU/5 mL Susp
Prophylaxis 50,000 IU TDS 250,000 IU TDS
L Treatment 100,000 IU QID 500,000 IU QID
< 40 kg: 9 mg/kg BD (D1), MD 8 mg/kg BD (D2 onwards)
Voriconazole IV > 40 kg: 6 mg/kg BD (D1), MD 3 to 4 mg/kg BD (D2 onwards)
200 mg/vial Inj [Max: 400 mg/dose]
50 mg Tab
200 mg Tab < 40 kg: 9 mg/kg BD
PO > 40 kg: 400 mg BD (D1), then 200 to 300 mg BD (D2 onwards)
[Max: 400 mg/dose]
HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM
HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
1 to 5 years: 5 to 10 mg OD
PO
Bisacodyl > 5 years: 10 to 20 mg OD
5 mg Tab; < 12 months: 2.5 mg
10 mg Supp PR 1 to 5 years: 5 mg
> 5 years: 10 mg
Glycerin Enema (RAVIN®)
PR 0.5 mL/kg up to TDS [Max: 50 mg/dose]
20 mL/tube
Lactulose 0.5 to 1.0 mL/kg up to TDS
PO
G 50 mg/vial Inj Hyperammonia: 1.0 to 2.0 mL/kg every 4 to 6 hours
Metoclopramide
I 10 mg/vial Inj;
IV/PO 0.1 to 0.3 mg/kg TDS [Max: 10 mg/dose]
T 10 mg Tab;
1 mg/mL Syrup
Omeprazole
IV 1 mg/kg BD [Max: 20 mg BD; OR 40 mg OD]
40 mg/vial Inj;
20 mg Cap;
PO 0.4 to 0.8 mg/kg BD [Max: 20 mg BD; OR 40 mg OD]
2 mg/mL Susp
Pantoprazole
IV 1 mg/kg OD to BD
40 mg/vial Inj
Ranitidine
IV 1 mg/kg TDS [Max: 50 mg/dose]
50 mg/vial Inj
Calcium Carbonate 50 mg BD, up to 500 mg QID
PO
500 mg Tab Dose increment based on Ca2+ level
Ferric Ammonium Citrate
Mixture Treatment: 6 mg/kg elemental iron OD
PO
400 mg/5 mL Prophylaxis: 2 mg/kg elemental iron OD
(80 mg elemental iron/mL) Mist
Folate/Folic Acid Suspension ≤ 4 years > 4 years
PO
1 mg/mL Susp 0.1 to 0.25 mg OD 0.5 to 1 mg OD
S
Multivitamin
U Multivitamin Elixir
PO 1 mL OD, up to 10 mL OD
P Infant/Children with disease that associated with Vitamin D deficiency
P (eg: Rickets, Osteogenesis Imperfecta, Cystic Fibrosis, Chronic Liver
Multivitamin Infant Drop
PO Disease and etc.)
L Appeton® 400 IU Vitamin D
1 mL OD
E Post-KASAI: may up to 3 mL OD
M Seizure: 30 mg/kg/day [Max: 1 g/day]
E Isoniazid induced Neuropathy: 5 to 10 mg OD (Prophylaxis)
Pyridoxine
PO 10 to 20 mg BD to TDS (Treatment)
N 10 mg Tab
Behavioural effect due to Levetiracetam: 100 to 200 mg/day
T [Max 6 mg/kg/day]
S Sodium Acid Phosphate
16 mmol/20 mL Tab PO Initially 1 mmol/kg BD, up to 3 mmol/kg daily in BD to QID
(0.8mmol/mL)
< 6 months 6 to 12 months ≥ 12 months
Vitamin A
PO 50,000 IU OD 100,000 IU OD 200,000 IU OD
50,000 IU/0.15 gm sachet
Duration: 2 days
Zinc Gluconate 1 to 2 mg/kg OD for 10 to 14 days
PO
50 mg Tab [Max: 10 mg (≤ 6 months); 20 mg (> 6 months)]
HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM
HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
SC/IM Central Diabetes Insipidus:
Desmopressin /IV 0.025 mcg/kg 1 to 2 doses/day [Max: 4 mcg/dose]
4 mcg/mL Inj < 2 years: 10 mcg BD to TDS
0.1 mg/tab PO 2 to 12 years: 50 mcg BD to TDS
> 12 years: 50 to 100 mcg BD to TDS
Dexamethasone
8 mg/vial Inj; LD: 0.6 mg/kg STAT; CROUP: 0.3 to 0.6 mg/kg STAT
IV/PO
4 mg Tab; MD: 0.25 mg/kg TDS to QID [Max: 20 mg/day]
0.5 mg/mL Susp
Fludrocortisone
PO Initially, 50 to 100 mcg OD OR 150 mcg/m2 OD [Max: 300 mcg/dose]
0.1 mg Tab
Hydrocortisone IV 2 to 4 mg/kg TDS to QID [Max: 100 mg/dose]
100 mg/vial Inj;
E 10 mg Tab; Congenital Adrenal Hyperplasia (CAH):
N PO
2 mg/mL Susp 11 to 25 mg/m2/day in 3 divided doses
D Age
Dose
O (mcg/kg/dose, daily)
0 to 3 months 10 to 15
C 3 to 6 months 8 to 10
R Levothyroxine 6 to 12 months 6 to 8
I 100 mcg Tab; PO 1 to 5 years 5 to 6
50 mcg Tab 6 to 12 years 4 to 5
N
> 12 years 2 to 3
E
Can be given at different doses on alternate days
(e.g.: 50 mcg on even days AND 75 mcg on odd days to give average dose
of 62.5 mcg/day) [Max: 200 mcg/day]
Methylprednisolone
1 gm/vial Inj; IV 10 to 30 mg/kg/day in 1 to 3 divided doses
500 mg/vial Inj
Indications Dose
Allergy; Asthma 1 to 2 mg/kg OD [Max: 60 mg/dose]
Prednisolone 60 mg/m2/day [Max: 80 mg/day] for 4 weeks;
PO Nephrotic
5 mg Tab then 40 mg/m2 EOD [Max 60 mg/day] for 4 weeks;
Syndrome
then reduce dose by 25% monthly over 4 months
Other indications 0.5 to 2 mg/kg/day in 1 to 2 divided doses
R Beclomethasone MDI: 100 to 200 mcg BD
MDI 100 mcg/puff; INHAL.
E EasyHaler: 200 to 400 mcg BD
EasyHaler 200 mcg/puff
S Budesonide
INHAL. MDI: 200 to 400 mcg BD
MDI 200 mcg/puff
P
Fluticasone Propionate
I INHAL. MDI: 125 to 250 mcg BD
MDI 125 mcg/puff
R Fluticasone Furoate
NASAL 1 to 2 sprays in each nostril OD
A Nasal Spray 27.5 mcg/spray
Fluticasone + Salmeterol
T MDI 125 mcg + 25 mcg/puff
INHAL. MDI: 1 to 2 puff BD
O Montelukast
R 10 mg Tab; 6 months to 5 years 6 to 14 years
PO
5 mg Tab; 4 mg ON 5 mg ON
Y 4 mg Granules
HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM
HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Inhaler ≤ 6 years > 6 years
400 to 600 mcg QID 800 to 1200 mcg QID
[Max: 600 mcg 4 hourly; [Max: 1200 mcg 4
Salbutamol MDI WITH Spacer
can up to hourly if hourly; can up to hourly
MDI 100 mcg/puff; INHAL.
required] if required]
EasyHaler 200 mcg/puff; MDI WITHOUT
2 mg/5 mL Syrup 200 mcg TDS to QID
Spacer
[Max: up to 4 Hourly]
EasyHaler
PO 0.1 to 0.15 mg/kg TDS [Max: 4 mg/dose]
Kawasaki: 30 to 50 mg/kg/day in 3 divided doses
Acetylsalicylic Acid (Aspirin)
PO Rheumatic Heart Disease: 80 to 100 mg/kg/day in 4 divided doses
300 mg Tab
MD: 3 to 5 mg/kg/day
Captopril
25 mg Tab; PO 0.1 mg/kg TDS [Max: 6 mg/kg/day in 3 to 4 divided doses]
1 mg/mL Solution
Clopidogrel
75 mg Tab; PO 0.2 mg/kg OD
5 mg/mL Susp
Digoxin 15 mcg/kg STAT.
250 mcg/mL Inj;
IV/PO After 6 hours, 5 mcg/kg then start MD 3 to 5 mcg/kg BD
C 62.5 mcg Tab
[Max: IV 200 mcg BD, Oral 250 mcg BD]
0.25 mg Tab
A Enalapril
R 5 mg Tab; PO 0.1 to 0.5 mg/kg OD to BD [Max: 40 mg/day]
D 20 mg Tab
Frusemide/Furosemide
I 20 mg/vial Inj;
IV/PO 0.5 to 2 mg/kg BD to QID [Max: 6 mg/kg/day; 80 mg/dose]
O 40 mg Tab;
V 10 mg/mL Syrup
Hydrochlorothiazide < 6 months: 2 to 3 mg/kg/day OR in 2 divided doses
A 25 mg Tab,
PO ≥ 6 months: 0.5 to 1 mg/kg BD [Max: 200 mg/day]
S 50 mg Tab,
5 mg/mL Susp
Heart Failure: 0.5 to 2 mg/kg BD
C
Metoprolol
U 100 mg Tab; PO 1 to 2 mg/kg BD to QID [Max: 6 mg/kg/day; 200 mg/day]
L 10 mg/mL Susp
A Nifedipine
10 mg Tab; PO 0.5 to 1 mg/kg BD to TDS [Max: 90 mg/day]
R 4 mg/mL Susp
Indications Dose
Anti-failure 0.2 to 1.5 mg/kg TDS to QID [Max: 80 mg/dose]
Propranolol DAY 1: 0.5 mg/kg/day in 3 divided doses for 1 day;
40 mg Tab; PO
Haemangioma DAY 2: 1.0 mg/kg/day in 3 divided doses for 1 day;
1 mg/mL Syrup
Dermatology DAY 3: 1.5 mg/kg/day in 3 divided doses for 1 day;
MD: 2.0 mg/kg/day in 3 divided doses

Spironolactone 0 to 10 kg 11 to 20 kg 21 to 40 kg > 40 kg
25 mg Tab; PO 1 mg/kg to
2.5 mg/mL Syrup
12.5 mg BD 25 mg BD 25 mg TDS
6.25mg BD

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Baclofen 0.2 mg/kg TDS
PO
10 mg/mL May increase every 3 days up to 1 mg/kg TDS if required
Carbamazepine (CBZ) 5 mg/kg/day in 1 to 2 divided doses; then increase every 2 weeks, to 10 to
400 mg CR Tab; 30 mg/kg/day in 2 to 3 divided doses
PO
200 mg Tab; CR tablet: 2 times/day
100 mg/5 mL Syrup Dose adjustment based on TDM recommendation
Clobazam
PO 0.1 mg/kg OD to BD, [Max: 0.4 mg/kg BD; 30 mg BD]
10 mg Tab
Clonazepam
2 mg Tab;
PO 0.01 mg/kg BD, increase to 0.1 mg/kg BD to QID [Max: 5 mg/day]
0.5 mg Tab;
0.1 mg/mL Susp
Diazepam IV 0.1 to 0.4 mg/kg [Max: 10 mg/course]
5 mg/mL Inj;
5 mg/PR PR 0.3 to 0.5 mg/kg [Max: 20 mg/course]
Lamotrigine 0.15 mg/kg OD
PO
100 mg Tab; 50 mg Tab If taking VPA/CBZ, double dose every 2 weeks [Max: 2 to 5 mg/kg/day]
Levetiracetam LD: 40 mg/kg over 10 mins
IV MD: 20 mg/kg BD [Max: 60 mg/kg/day in 2 to 3 divided doses; 1.5
N 250 mg/vial Inj;
500 mg Tab; gm/dose BD]
E 250 mg Tab; 10 mg/kg BD
U 100 mg/mL Solution PO
[Max: 60 mg/kg/day in 2 to 3 divided doses; 1.5 gm/dose BD]
R Midazolam
O 15 mg/vial Inj; IV 0.1 to 0.2 mg/kg [Max: 10 mg/dose]
5 mg/vial Inj
L
LD: 20 mg/kg [Max: 40 mg/kg/day; 1.5 gm/dose] over 30 mins
O Phenytoin IV MD: 4 to 8 mg/kg/day in 2 to 3 divided doses [Max: 600 mg/day]
G 100 mg/vial Inj; Dose adjustment based on TDM recommendation
Y 100 mg Cap;
30 mg Cap 4 to 8 mg/kg/day in 2 to 3 divided doses [Max: 600 mg/day]
PO
Dose adjustment based on TDM recommendation

LD: 20 mg/kg [Max: 40 mg/kg/day; 1.0 gm/dose] over 30 mins

Phenobarbitone IV MD: 2.5 mg/kg BD [Max: 4 mg/kg/dose]
200 mg/vial Inj; Dose adjustment based on TDM recommendation
30 mg Tab;
10 mg/mL Susp MD: 2.5 mg/kg BD [Max: 4 mg/kg/dose]
PO
Dose adjustment based on TDM recommendation

LD: 0.5 to 1.0 mg/kg/day, then increase every 2 weeks by 1 mg/kg/day in 2

Topiramate
PO divided doses
50 mg Tab
MD: 5 to 9 mg/kg/day
LD: 20 to 40 mg/kg [Max: 1.25 gm/dose] over 5 to 10 minutes at 20 to 40
Valproic Acid (VPA)
mg/min
400 mg/vial Inj;
IV/PO MD: 5 mg/kg BD OR infusion at 1 to 5 mg/kg/hour [Max: 20 mg/kg BD to
200 mg Tab;
200 mg/5 mL Syrup TDS]
Dose adjustment based on TDM recommendation

Vigabatrin
PO 25 mg/kg BD [Max: 150 mg/kg/day]
500 mg Tab

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

HOSPITAL SULTANAH NUR ZAHIRAH (HSNZ) PAEDIATRIC COMMON MEDICATION DOSING 2021 – 1st edition 2021

PAEDIATRIC COMMON MEDICATION DOSING IN HSNZ

MEDICATION RoA DOSE
Allopurinol Prophylaxis of hyperuricemia associated with cancer chemotherapy:
300 mg tab PO
10 mg/kg/day OD OR in divided doses [Max: 300 mg/dose]
20 mg/mL Susp
Chloral Hydrate
PO Initially 10mg/kg TDS to QID, can be up to 50mg/kg QID [Max: 2 g/dose]
200 mg/5mL Mixt.
Age Dose
Chlorpheniramine 1 to 5 months 0.25 mg/kg TDS to QID [Max: 2.5 mg/dose]
10 mg/vial Inj; IV 6 months to 5 years 2.5 mg TDS to QID
4 mg Tab; 6 to 11 years 5 mg TDS to QID
2 mg/5 mL Syrup > 12 years 10 mg TDS to QID
PO 0.1 mg/kg TDS to QID [Max: 4 mg/dose]
Hepatitis Immunoglobulin
Prophylaxis of Hepatitis B after Hepatitis B Virus Exposure
100 unit/0.5 mL Inj; IM
M 32 to 48 unit/kg, preferred within 48 hours of exposure OR within 7 days
200 unit/1 mL Inj
I Human Albumin 20%: 2 to 5 mL/kg
20% vial Inj; IV
S 5% vial Inj 5%: 10 to 20 mL/kg/course
C Kawasaki; Rheumatic fever: 2 gm/kg over 12 to 16 hours
E Human Normal
Immune Thrombocytopenic Purpura (ITP)/Guillain-Barré syndrome (GBS):
L 1 gm/kg over 12 to 16 hours
Immunoglobulin (IG)
IV
L 3.0 gm/vial Inj;
Test dose:
2.5 gm/vial Inj
A 5 mL/hour for 15 mins; then 10 mL/hour for 15 mins; then 15 mL/hour for
N 15 mins; then 20 mL/hour for 15 mins
Ibuprofen
E 200 mg Tab
PO 5 to 10 mg/kg TDS [Max: 2.4 gm/day]
O Loratadine < 12 kg 12 to 30 kg > 30 kg
U 10 mg Tab; PO
2.5 mg OD 5 mg OD 10 mg OD
1 mg/mL Syrup
S Plan A: 10 mL/kg [Max: 250 mL/dose] per purge up to 3 Hourly

Oral Rehydration Salt Plan B: Weight (kg) x 75 to be given in first 4 hours

PO
Dilute 1 sachet in 250 mL water
< 6 kg 6 to 10 kg 10 to 12 kg 12 to 19 kg
200 to 400 mL 400 to 700 mL 700 to 900 mL 900 to 1400 mL
Paracetamol
1000 mg/vial Inj;
IV/PO 10 to 15 mg/kg QID [Max: 60 mg/kg/day; 500 mg/dose; 4 gm/day]
500 mg Tab;
250 mg/5 mL Susp;
LD: 40 mg/kg STAT
250 mg/Supp; PR MD: 30 mg/kg 6 Hourly [Max: 5 gm/day]
125 mg/Supp Round up to the nearest suppository strength
Vitamin K
1 mg/mL Inj; IV 0.3 mg/kg OD [Max: 10 mg/dose]
10 mg/mL Inj
REFERENCES
th
Paediatric Protocol 4 Edition
Drug Doses by Frank Shann 2017 edition
British National Formulary for Children 2019-2020
National Antibiotic Guideline 2019
**p/s : please refer to Frank Shann/ BNF for medication that are not listed here

HOSPITAL SULTANAH NUR ZAHIRAH PAEDIATRIC PHARMACY TEAM

Aciclovir REFERENCES
Adrenaline (HCl) I 1 Handbook of Injectables Drugs, 16th Edition, by Lawrence A., Trissel. FASHP, copyright 2010, American
Alprostadil C Society of Health-System Pharmacist.

Amikacin (Sulphate) C C 2 Intravenous Medications Compatibility Chart, Department of South Australia, last revised Oct 2017.
Aminophylline C I C 3 Drug Dose. 17th Edition. Frank Shann.
Amiodarone HCl I C C I 4 Micromedex Neofax Essentials 2014.
Amphotericin B (desoxycholate) I I C C Editors:
Ampicillin C C/I I Saidatul Aqilah Hashim @ Abdullah
Ampicillin-Sulbactam I I C/I I NA Noor Shukriah Hassan
Benzylpenicillin (Sodium) C C C C I C I NA NA
Calcium Gluconate C C C C C I C C
Cefotaxime C C C C C I C C
Ceftazidime C C C C I C C NA C Compatible; when administered via Y-site (when both medications using same dilution solution)
Clindamycin C C C C I C C C C C C C* Compatible; when using specific concentration (refer Micromedex)
Cloxacillin C I C C C C C C C C I Incompatible; do NOT administer via Y-site.
Dexamethasone sodium C C C* C C C I I C C C/I Some references shows Compatible; when administered via Y-site &
Digoxin C C C C I I C C* C C C C C C C some shows Incompatible; do NOT asminister via Y-site.
Dobutamine I C C C I C I I I C C I C I I C/I
Dopamine I C C C C C I C C C C C C C C C No data available.
Esmolol C C C I C C C C C C C I C C C NA NOT applicable (polypharmacy)
Fentanyl C C C C* C C C C C* C C C C C C C C C/I C C
Fluconazole C C C C C I I C C C C C C* C C C/I C C C C All blood product are not recommended to administer together with any medication.
Flumazenil C C C
Frusemide C C C C ICI C* C C C C
C C C C I C/I I C I
Gentamicin (Sulphate) I C C NA C I C* C* C C C C
C C* I C C C C C C I
Glyceryl Trinitrate (GTN) C* C* C C* C* C* C C* C* C* C* C* C*
C I C* C* C* C C* C* C* I C*
Hydralazine I I I I I
C* C* C* C* C C* C C* C I C*
Hydrocortisone Sodium C C C C C* I C I C C
C C C C I C I C C C I C* C
Heparin C C C I C I C C C C C C C
C C C C I C C C C C C I C* C C/I
Insulin (regular) I I C C C C C/I I I C C C C C C* C C C
Imipenem-Cilastatin C I I C C NA NA C C C C* C C C I C I C* C C C
Ketamine I C C C I C C C C C C C C C I C C I I
Labetalol I C* C* C* C* I C* C* I C* I C* C* I I C* C* C* C* C* C* I C* C C* I C* I C
Levetiracetam
Magnesium Sulphate C C I I C/I C C C C C C C C I C C C C C C C C I C C C C C*
C* C*
Meropenem I C I I NA NA C C C C C C C C C C C C C I C C
Methylprednisolone C C C C C* I I C I I C C C C C C C C/I C C C C C* I C C C C C* C* I
Metoclopramide C C C I C I I C C C C C C C C C C C I C C* C* C C C C C C* C C C
Metronidazole C C C C C C C C C C C C C C C C C C C C C/I C C C C C C C C C* C C/I C C
Midazolam I C C C C/I C I I I C C C I C* I I C I C C C C I C C* C* C C/I C C C C* C C C C
Milrinone C C C C C C C C C C C C C C C C I C C I C C* C C C C I C C* C C C C C C
Morphine Sulphate C C C C C C I C C C C C C C I C C C C C C C C/I C C* C C C C C C* C C C C C C C
Noradrenaline tartrate C C I C I I C C C C C C C C C C C C C C/I C C* I C C I C C* C C C C C C C C
Octreotide C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C
Pantoprazole C I I I I C C C I I C* I I I I I I I I I I I I C I I C I I I I I I I I I I
Paracetamol I C C* C C* C C* C C C* C* C* C* C
Phenobarbitone sodium C I C C C C I C I C C C C I C I C C C C C* I C C I C* C* C C C C C I C C I C I
Phenytoin sodium I I I I I I I I I I I I I C I C I I I I C I I I I I I I I I I I I I I I I
Piperacillin-Tazobactam I C I C I I C I C C C C I C C C C C I C I C C I NA C I C C C C I C C C C I C I
Potassium Chloride C C C C C C I C C* C C C C C C C C C C C C C C C C C C C C C C C* C C C/I C C C/I C C C C C C* C I C
Potassium Dihydrogen Phosphate I I C I C C C C I I C
Ranitidine C C C C I C C C C C C C C C C C C C C C C C C C* C* C C I C C C* C C C C C C C C C C I C/I C C
Salbutamol I C C C I
Sodium Bicarbonate C I C C I C/I C/I C/I C I I C C C C C I I C/I C C C C C* C* C C C I I C C/I I C I C I C C I C I C I C C C
SMX+TMP (Bactrim) C* I I I I I I I I I I I I I I I I I C* I I I I I I I C* I I I C* C* I I C I C* C* I C* C* I I C* I I I
Vancomycin C C C C C C C C C I I C NA C/I C C C C C C I C C* C* C/I I C C* C C* C C I C C C C C C C I C/I I C/I C C C I
Zidovudine C C C I C C C C C C C C C C I C C C C C C C C C C* C
TPN C/I I I C C C C C I C C C C I C C C C C I C C C I C C
Lipid I C I I C C C C C C I C C C C C I C C I I C I I C C C C

MEDICATIONS

Aciclovir
Adrenaline (HCl)
Alprostadil
Amikacin (Sulphate)
Aminophylline
Amiodarone HCl
Amphotericin B (desoxycholate)
Ampicillin
Ampicillin-Sulbactam
Benzylpenicillin (Sodium)
Calcium Gluconate
Cefotaxime
Ceftazidime
Clindamycin
Cloxacillin
Dexamethasone sodium
Digoxin
Dobutamine
Dopamine
Esmolol
Fentanyl
Fluconazole
Flumazenil
Frusemide
Gentamicin (Sulphate)
Glyceryl Trinitrate (GTN)
Hydralazine
Hydrocortisone Sodium
Heparin
Insulin (regular)
Imipenem-Cilastatin
Ketamine
Labetalol
Levetiracetam
Magnesium Sulphate
Meropenem
Methylprednisolone
Metoclopramide
Metronidazole
Midazolam
Milrinone
Morphine Sulphate
Noradrenaline tartrate
Octreotide
Pantoprazole
Paracetamol
Phenobarbitone sodium
Phenytoin sodium
Piperacillin-Tazobactam
Potassium Chloride
Potassium Dihydrogen Phosphate
Ranitidine
Salbutamol
Sodium Bicarbonate
SMX+TMP (Bactrim)
Vancomycin
Zidovudine
TPN
Lipid

HSNZ Neonatal/Pediatric Intravenous Compatibility Chart 2021

Pharmacy Department
Hospital Sultanah Nur Zahirah, Terengganu