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Set the stage for

ventilator Are you puzzled by ventilator modes? We help you differentiate


between invasive and noninvasive ventilation and understand the
2.0 common settings for each.
ANCC
CONTACT HOURS
By Nichole Miller, BSN
Direct Care Nurse, ICU • Dwight D Eisenhower Army Medical Center • Fort Gordon, Ga.

Your patient in the ICU today is Mrs. J, Invasive ventilation


who was intubated for hypercapnic Invasive positive pressure ventilation
respiratory failure yesterday after she requires that the patient be intubated
failed a trial on bilevel positive airway by placing an endotracheal (ET) tube to
pressure (BIPAP). Her ventilator settings provide direct ventilation to the lungs.
are assist control (AC), 12; tidal volume It’s indicated for patients who aren’t
(TV), 600; positive end-expiratory pres- breathing (apneic) or breathing ineffec-
sure (PEEP), 5; and Fio2, 40%. You sud- tively, causing ventilation problems.
denly feel like you’re on another planet Intubation is necessary for any patient
and people are speaking a different with impending or current respiratory
language. In this article, we’ll show you failure. There are no specific contraindi-
how to identify the difference between cations to mechanical ventilation when a
invasive and noninvasive ventilation, patient isn’t breathing, but facial, neck,
understand the basic mechanisms of dif- or tracheal trauma can make oral intu-
ferent ventilator modes, and interpret the bation undesirable (see Indications for
ventilator settings. mechanical ventilation).
Almost all ventilators have the capability
of being set to four basic modes: AC, syn-
chronized intermittent mandatory ventilation
Indications for mechanical ventilation (SIMV), airway pressure release ventilation
• Partial pressure of oxygen in arterial blood (PaO2) < 50 mm Hg with FiO2 > 0.60
(APRV), and pressure support (PS). Most
• PaO2 > 50 mm Hg with pH < 7.25
• Vital capacity < two times TV
newer ventilators can also be set to specialty
• Negative inspiratory force < 25 cm H2O modes, such as high frequency oscillatory
• Respiratory rate > 35/minute ventilation (HFOV).
Let’s take a closer look at these standard
Source: Smeltzer SC, Bare BG, Hinkle JL, Cheever KH. Brunner and Suddarth’s Textbook of
Medical-Surgical Nursing. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.
ventilator modes (see Picturing modes of
mechanical ventilation).

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settings

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Assist control for a small person and up to 800 mL for a


AC is one of the most common modes used larger person.
for ventilation in the ICU. It’s often used for Measured as a percentage, FiO2 is the
patients who require the most support from amount of oxygen the patient requires to
the ventilator. When looking at the ventila- maintain appropriate blood oxygen levels.
tor, you’ll see that there are several basic PEEP is the pressure that’s applied at the
settings within AC mode. These include the end of the expiratory phase that helps keep
respiratory rate, TV, Fio2, and PEEP (see the alveoli from snapping shut when the
Initial ventilator settings). Let’s look at each patient exhales. This can minimize the risk of
one of these terms. developing atelectasis and prevent shearing
The respiratory rate is the minimum force trauma to the alveoli. Shearing is
amount of breaths that the patient will caused when the alveoli are opening and
be allowed to take. This rate is pro- shutting too quickly. PEEP can also be used
grammed into the ventilator, often set to help open areas of collapsed alveoli, also
between 12 and 18. known as atelectasis. PEEP is measured in
TV is the amount of air that will go into centimeters of water and is often seen at
the patient’s lungs with each breath. This is levels between 5 and 10 cm H2O.
based on the ideal body weight of the In AC mode, the patient will have a set
patient, most often calculated at 10 mL/kg. respiratory rate, meaning that it’s a time-
Some patients may require a smaller TV triggered mode. If for some reason the
due to poor lung compliance (the amount patient doesn’t initiate a breath on his or her
of stretch the lungs can handle without own after so many seconds, the ventilator
damage). TV is usually set between 400 mL will sense that the patient hasn’t attempted a
breath and will deliver the TV. The time
between breaths is based on the set respira-
Initial ventilator settings tory rate. For example, if the respiratory rate
The following guide is an example of the steps involved in operating a is set to 12 and there’s no breath initiated
mechanical ventilator. The nurse, in collaboration with the respiratory within 5 seconds, the ventilator will give the
therapist, always reviews the manufacturer’s instructions, which vary patient a controlled, or ventilator-dependent,
according to the equipment, before beginning mechanical ventilation. breath. The ventilator will give this set num-
1. Set the machine to deliver the TV required (10 to 15 mL/kg). ber of breaths every minute as long as the
2. Adjust the machine to deliver the lowest concentration of oxygen to patient isn’t attempting to breathe. The venti-
maintain normal PaO2 (80 to 100 mm Hg). This setting may be high
lator won’t allow the patient to breathe less
initially but will gradually be reduced based on ABG results.
than the set amount.
3. Record peak inspiratory pressure.
4. Set mode (AC or SIMV) and rate according to the healthcare provider’s
If the patient is capable of taking breaths
order. Set PEEP and PS if ordered. on his or her own, the ventilator will sense
5. Adjust sensitivity so that the patient can trigger the ventilator with a that the patient is taking a breath by the neg-
minimal effort (usually 2 mm Hg negative inspiratory force). ative flow of air and will help facilitate the
6. Record minute volume and obtain ABGs to measure partial pressure of breath by delivering the set TV. The patient
carbon dioxide, pH, and PaO2 after 20 minutes of continuous mechanical can breathe as many times a minute as he or
ventilation. she wants but will get the same TV with
7. Adjust setting (FiO2 and rate) according to results of ABG analysis to pro- each breath.
vide normal values or those set by the healthcare provider. The benefit of AC mode is that it can be
8. If the patient suddenly becomes confused or agitated or begins bucking
used in both patients who are spontaneously
the ventilator for some unexplained reason, assess for hypoxia and
breathing and those who aren’t. It will pro-
manually ventilate on 100% oxygen with a resuscitation bag.
vide the set number of breaths every minute,
Source: Smeltzer SC, Bare BG, Hinkle JL, Cheever KH. Brunner and Suddarth’s Textbook of
Medical-Surgical Nursing. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007. but also allow patients who want a higher
rate to initiate breaths on their own. This can

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Picturing modes of mechanical


ventilation
decrease anxiety by allowing the patient to
set his or her own respiratory rate while still 
being supported by the full TV. 9ROXPH
For weak or critically ill patients, the FF

ventilator does most of the work, meaning
that the patient doesn’t have to do much of &RQWUROOHGYHQWLODWLRQ
the work of breathing. The downside of
using this mode is that every breath is the 

same size. If the TV is set at 600 mL, then 9ROXPH


FF
every breath (both spontaneous and assisted) 
will be approximately 600 mL. After the
volume has been delivered, a valve closes $&
in the circuit and the patient is forced to 
exhale. However, a person’s normal breath- 9ROXPH
ing pattern doesn’t include identical FF
breaths. If a patient wants larger breaths 
than the set TV, it can cause anxiety and
6,09
interrupt the patient’s breathing pattern,
which may lead to resistance in ventilation. 
This can lead to tachypnea and hyperventi- 9ROXPH
lation, which, in turn, may result in respira- FF
%DVHOLQHIXQFWLRQDOUHVLGXDOFDSDFLW\HOHYDWHG
tory alkalosis. 
Another common issue seen with the use 3((3 6HUYR
of AC mode is often caused by the low work YHQWLODWLRQ 69
 ZLWK
of breathing. When patients have been in
9ROXPH &3$3
this mode for a period of time, it can cause
FF
weakened respiratory muscles and increase 
in ventilator times. Sedation, appropriate
volumes, and weaning trials can often help &3$3 69
ZLWK
decrease these complications.  36
9ROXPH
Synchronized intermittent FF
mandatory ventilation 
SIMV is also a common mode of ventila- 36
tion used in the ICU. It works on the same
basic principles of AC mode—a set num- 
ber of breaths will be delivered each 9ROXPH
minute, but the patient can breathe as P/

many times a minute as he or she feels
the need to. These breaths can be patient- $359
or ventilator-initiated, but the difference ,QVSLUDWLRQDLUIORZ
is how TV is delivered. All ventilator- ([KDODWLRQ
initiated breaths will have the full TV 3DWLHQWWULJJHUHGEUHDWK
delivered, but for patient-initiated breaths, 6SRQWDQHRXVLQVSLUDWLRQRQORZSUHVVXUHOHYHO

the set respiratory rate will be an indepen- 6SRQWDQHRXVLQVSLUDWLRQRQKLJKSUHVVXUHOHYHO
dent breath and the TV won’t be deliv-
Source: Smeltzer SC, Bare BG, Hinkle JL, Cheever KH. Brunner and Suddarth’s Textbook of Medical-
ered. The patient will need to inhale the Surgical Nursing. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.
TV independently.

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The rationale behind using SIMV instead helps determine at what point the patient is
of AC is to help work the patient’s respiratory ready for extubation.
muscles by providing periods of decreased The downside of SIMV is often
support. Remember, if the respiratory rate seen when it’s used with weakened or
is set high or the patient isn’t breathing critically ill patients. The increased work
spontaneously, then this mode functions of breathing can actually cause a patient
identically to AC mode. to tire out and lead to longer intubation
The benefit of using SIMV is seen most times or failed weaning attempts. Other
often in surgical patients who require venti- issues include hypoventilation from the
lator support for a short period of time post- inability to take adequate TV with inde-
operatively. As the patient wakes up, he or pendent breaths and anxiety from not
she is able to take an increasing number of knowing what breaths will be assisted
unassisted breaths. By using this mode, it or unassisted.

Troubleshooting problems with mechanical ventilation


Problem Cause Considerations
Ventilator problems
Increase in peak airway Coughing or plugged airway tube Suction airway for secretions; empty
pressure condensation fluid from circuit.
Patient “bucking” ventilator Adjust sensitivity.
Decreasing lung compliance Manually ventilate patient.
Assess for hypoxia or bronchospasm.
Check ABG values.
Sedate only if necessary.
Tubing kinked Check tubing; reposition patient; insert oral
airway if necessary.
Pneumothorax Manually ventilate patient; notify healthcare
provider.
Atelectasis or bronchospasm Clear secretions.
Decrease in pressure or loss Increase in compliance None
of volume Leak in ventilator or tubing; cuff on tube/ Check entire ventilator circuit for patency.
humidifier not tight Correct leak.

Patient problems
Cardiovascular compromise Decrease in venous return due to application of Assess for adequate volume status by
positive pressure to lungs measuring heart rate, BP, central venous
pressure, pulmonary capillary wedge pressure,
and urine output. Notify healthcare provider if
values are abnormal.
Barotrauma/pneumothorax Application of positive pressure to lungs; high Notify healthcare provider.
mean airway pressures lead to Prepare patient for chest tube insertion.
alveolar rupture Avoid high pressure settings for patients with
chronic obstructive pulmonary diease, ARDS,
or history of pneumothorax.
Pulmonary infection Bypass of normal defense mechanisms; Use meticulous aseptic technique.
frequent breaks in ventilator circuit; Provide frequent mouth care.
decreased mobility; impaired cough reflex Optimize nutritional status.

Source: Smeltzer SC, Bare BG, Hinkle JL, Cheever KH. Brunner and Suddarth’s Textbook of Medical-Surgical Nursing. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2007.

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Airway pressure release ventilation a traditional ventilator. This mode, along


APRV is considered a rescue method of with APRV, is considered a rescue mode of Invasive
ventilation and is often used for patients ventilation and is most commonly used in ventilation
who are having problems with lung com- adult patients with ARDS or for neonates usually requires
pliance or difficulty with oxygenation. This with neonate respiratory distress syndrome weaning.
is a fairly advanced and complicated mode or meconium aspiration. The benefit of
of ventilation, most commonly used in pa- using this type of ventilation is that it has
tients who have acute respiratory distress been shown to significantly improve oxy-
syndrome (ARDS). APRV uses an inverse genation when conventional methods have
ratio to achieve higher levels of pressure, been unsuccessful by sustaining very high
meaning that the expiratory phase is levels of PEEP almost continuously. This
longer than the inspiratory phase. This high level of PEEP helps provide enough
allows higher levels of pressure to be held pressure to reopen areas of collapsed
throughout the respiratory cycle, although alveoli (atelectasis), often referred to
this isn’t how we normally breathe. How- as recruitment.
ever, compared with older modes that used The downside of HFOV is the potential
an inverse ratio, APRV is much more com- for the development of pneumothorax or
fortable for patients and allows for sponta- other barotrauma. There’s also a potential for
neous breathing. The patient can take a complications from the use of paralytics,
breath at any point in the ventilator cycle, sedation, and pain medication. All three are
making the high pressures more tolerable. required for patients to tolerate HFOV. This
These high pressures combined with can lead to difficulty in assessing neurologic
PEEP help improve and prevent areas function or when transitioning the patient to
of atelectasis. This is one way that APRV a conventional mode. These patients are
helps improve oxygenation when other often critically ill and require frequent close
modes can’t. monitoring of arterial blood gases (ABGs)
Improved oxygenation is the biggest bene- and one-to-one nursing care.
fit to using this mode. It has often been
shown to significantly improve oxygenation Pressure support
in patients who are very difficult to oxygenate PS is considered a weaning mode used to
otherwise. This is commonly seen in patients assess the patient’s readiness for extubation.
with ARDS because of the decrease in lung It doesn’t use a set respiratory rate and is a
compliance and dense areas of atelectasis. pressure-driven mode rather than a time-
Another benefit seen over the use of other triggered one. PS requires the patient to
inverse ratio modes is that paralysis and initiate each breath and then that breath is
heavy sedation aren’t required because assisted through the ET tube with a set
patients can breathe anywhere in the pressure amount of pressure. This support helps
cycle. overcome the resistance of the ET tube.
There are more risks with the use of When this mode is used, the pressure is
APRV than with the other modes, including often started at a high rate, such as 20 cm
a higher incidence of pneumothorax and H2O, and titrated to usually 8 cm H2O
other ventilator trauma injuries because of before extubation. The lower the pressure,
the higher levels of pressure combined with the more work the patient needs to do to
the decrease in patient lung compliance. pull adequate TV through the ET tube. After
the patient has been weaned to the lowest
High frequency oscillatory ventilation amount of PS and is able to achieve ade-
Used when all other modes fail to improve quate TV while maintaining oxygenation, it
oxygenation, HFOV isn’t usually found on suggests that he or she will be able to be

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successfully extubated. PS can also be used and unable to pull enough TV to maintain
in conjunction with SIMV as additional adequate ventilation. Poor ventilation can
assistance for independent breaths. lead to hypercapnia and respiratory acidosis.
When assessing a patient in this mode, it’s Alarm limits should be set to detect patterns
important to ensure that he or she is getting of low volumes to help decrease this risk.
adequate TV. Remember that the patient Tachycardia and tachypnea can also be signs
should be achieving volumes between 400 that a patient may need a higher level of
and 800 mL based on body weight. The pressure or require rest in AC mode. Often,
amount of time that a patient remains in PS patients who’ve been on mechanical ventila-
mode will depend on how ready he or she is tion for an extended period of time have a
for extubation. Weaning often starts with weak diaphragm due to the decreased work-
short periods of high pressures; as the load of breathing while on the ventilator.
patient tolerates the trial, the periods can be These patients may require higher levels of
extended and the pressure decreased. Strong support and many days of weaning trials
patients may do a PS trial for less than an before extubation.
hour and then be extubated. Patients who
are weak, who suffer from chronic lung Noninvasive ventilation
disease, or who’ve been intubated for Sometime patients don’t need to be intu-
long periods of time may take several days bated but need breathing support. When
or even weeks with daily trials to be ready respiratory failure is pending, the health-
for extubation. care team will often take the least aggres-
The biggest benefit of using the PS mode sive method of providing appropriate
is that it acts as a stepping stone between a ventilation. Noninvasive ventilation can
dependent ventilator mode and extubation. be an effective alternative to intubation.
This helps decrease the risk of reintubation There are two different methods of non-
by allowing adequate assessment of the invasive ventilation that can be used in
patient’s ability to breathe independently. this situation: BIPAP and continuous
It also helps work the respiratory muscles to positive airway pressure (CPAP). Both
get them ready for independent breathing. use a mask that’s placed over the nose
The downside of PS is that the increased or face delivering positive airway pres-
work of breathing can leave the patient tired sure and oxygen to help assist breathing.
These methods are to be used only for a
patient who’s breathing spontaneously.
did you know? Let’s take a closer look.
The use of ventilators has been recorded since the early 1800s, but
modern ventilation was first used in the 1940s. The early mechanism was Bilevel positive airway pressure
based on keeping the chest in a negative-pressure environment that was BIPAP provides positive airway pressure
contained in a closed system such as the “iron lung.” As technology
during both inspiration and exhalation.
advanced, so did the benefits. Healthcare providers were able to perform
This helps assist patients who are spontane-
surgeries that weren’t possible without mechanical ventilation, and many
patients who previously wouldn’t have survived recovered from infections
ously breathing with ventilation and gas
such as pneumonia. However, there were also drawbacks. The equipment exchange.
was large and difficult to use, most ICUs weren’t able to handle more than BIPAP is useful in assisting patients with
four or five ventilated patients, and there was difficulty maintaining achieving full TV, leading to improved ven-
adequate ventilation. Today’s advanced ventilators are portable and use tilation in patients with impending respira-
positive pressure—the forcing of gases into the chest—instead of tory failure. It can also provide supplemental
negative pressure. Patients are no longer placed inside the ventilator; an oxygen along with inspiratory pressure.
ET tube is all that’s required. BIPAP is often used with patients who are
hypercapnic or who have elevated levels of

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carbon dioxide (CO2). It helps improve ven- to the cuff or finding the leak in the circuit
tilation and decrease high CO2 levels, but will resolve this type of alarm (see Trouble- If you need help
can only be used in patients who are able to shooting problems with mechanical ventilation). breathing,
breathe independently. BIPAP isn’t appro- Caring for an intubated patient also noninvasive
priate for a patient who’s apneic or who has requires a basic care routine and assessment ventilation may
a low respiratory rate. skills. Each ET tube is marked in centimeters,
be used.
and the position should be checked every
Continuous positive airway pressure 4 hours. When checking the tube’s position,
CPAP is a noninvasive form of PEEP. It can it’s also a good time to assess for skin integ-
be provided through a ventilator as a sepa- rity, the stability of the securement device,
rate mode, but can also be delivered via and lung sounds. Mouth care
an independent machine. CPAP is most should also be provided
commonly delivered through a small mask every 4 hours, and the
that’s worn over the nose, but can also be patient’s teeth should be
provided through a full-face mask. brushed twice a day to
CPAP provides a constant end-expiratory decrease the incidence
pressure that helps keep the airway open; of ventilator-acquired
some machines also provide supplemental pneumonia.
oxygen if required by the patient. Because this You also need to be
type of noninvasive ventilation provides con- aware of the complications of mechanical
stant airway pressure, it’s most often used for ventilation. Two of the most dangerous are
patients with obstructive sleep apnea (OSA). volutrauma and barotrauma. Volutrauma is
The biggest benefit of CPAP is decreasing often caused by a TV that’s too high, causing
or even eliminating the adverse reactions of overdistension of the alveoli and leading to
OSA. The positive pressure helps prevent edema at the level of the alveoli where oxy-
obstruction while the patient is sleeping and genation takes place. Barotrauma is caused
allows for effective ventilation and oxygen- by elevated pressure in the lungs from high
ation. Patients most often complain about levels of PEEP. Most often seen in patients
wearing the mask but, for most, the improved who have decreased lung compliance, such
quality of sleep outweighs the discomfort. as in ARDS or pulmonary fibrosis, the first
signs of barotrauma are low oxygen levels,
Nursing considerations tachypnea, agitation, and high airway pres-
As the nurse caring for an intubated patient, sures.
it’s important to be aware of the different For patients receiving BIPAP or CPAP,
alarms you may encounter. One of the most you must assess the quality and rate of respi-
common alarms is a high pressure alarm, rations. If respirations change or decrease, it
which may mean that there are secretions may be a sign of worsening respiratory fail-
present and the patient requires suctioning ure. Lung sounds should also be assessed at
or that the patient is biting on the ET tube regular intervals to evaluate adequate air
and may require more sedation. Most movement.
intubated patients will require some seda- Like invasive ventilation, there are also
tion and analgesia to make tolerating the alarms associated with noninvasive ventila-
ET tube more comfortable. The other com- tion. The most common cause of alarms is
mon alarm is a low pressure alarm, which low volume due to a leak in the seal between
may indicate that there’s an air leak in the the mask and the patient’s face. Readjustment
ventilator circuit or the cuff on the end of the of the mask to a tighter seal will usually
ET tube and air is leaking past the cuff and resolve this problem. Other alarms may be
out of the patient’s mouth. Adding some air for low or high respiratory rates or low TV,

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meaning that the patient isn’t breathing deep allow you to assess what the next step for
enough. These alarms may indicate that the your patient will be. ■
patient isn’t tolerating the therapy and may
require intubation. ABG monitoring may be Learn more about it
needed to determine if a patient is tolerating Adams AB. Too many ventilator modes! Respir Care.
2012;57(4):653-654.
noninvasive ventilation.
Daoud EG, Farag HL, Chatburn RL. Airway pressure
release ventilation: what do we know? Respir Care.
Ready, set, go! 2012;57(2):282-292.

Invasive and noninvasive ventilator modes Kacmarek RM. The mechanical ventilator: past, present,
and future. Respir Care. 2011;56(8):1170-1180.
aren’t as daunting as you may think. Venti- Siau C, Stewart TE. Current role of high frequency
lators have come a long way over the years oscillatory ventilation and APRV in acute lung injury
and acute respiratory distress syndrome. Clin Chest Med.
and are often seen in the ICU, ED, and OR 200;29(2):265-275.
settings. When working in these areas, or Singer BD, Corbridge TC. Basic invasive mechanical
Want more
in other areas that commonly use ventila- ventilation. South Med J. 2009;102(12):1238-1245.
CE? You tors, it’s important to know how to inter-
got it! pret the settings. Knowing the ventilator The author and planners have disclosed that they have no financial
relationships related to this article.
mode that your patient is on will help you
identify what settings will be present and DOI-10.1097/01.NME.0000428429.60123.f7

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