DRUG STUDY

Name: Ruby R. Santillan BSN

Drugs Dose Method of Indications Effect on Effect on

Administration Labor Mother &
Progress Effect on
Fetus
Morphine 0.2 to 2.3 Subcutaneous, Relief of May reduce Morphine
Sulfate mg/kg/dose Intramuscular moderate to the strength, may affect
PO every 12 or Intravenous severe acute and duration and baby’s
hours route. chronic pain frequency of development
where use of an uterine in the first
opioid analgesic contractions trimester
is appropriate resulting in taking
prolonged morphine at
labor the end of
pregnancy
has a risk that
the baby will
get
withdrawal
symptoms
when they’re
born
Bupivacaine 2 mg/kg By injection Local or regional It produces Can cause
(without anesthesia good sensory maternal
epinephrine) analgesia surgical blockade with hypotension
2.5 mg/kg obstetric or minimal or no as well as
(with diagnostic motor fetal
epinephrine) procedures blockade bradycardia
Or 150 mg
Lidocaine 5mL Subcutaneous, Local or regional Does not Almost no
(100mg/5ml ) Intramuscular, anesthetics. prolong the negative
As needed Intravenous Mnagement of active – first effect on the
Injection, acute ventricular and second the mother
Transdermal arrhythmias stages of and the fetus
during cardiac labor
manipulation
control of status
epilepticus
refractory to
other treatments
Thiopental IV 25 to 75 Intravenous As the sole Induces Thiopental
Soduim mg; observe route only anesthetic agent tachycardia, should be
for 60 se. for brief ( 15 min) and incidence used during
 procedures of ventricular pregnancy
fibrillation is only if the
increased possible
benefit
outweighs the
possible risk
to the unborn
baby
Naloxone 0.4- 2 mg IV, Intravenous Reversal narcotic Significantly Can cause
Hydrochloride I/O, Nasal. Infusion induced increased the withdrawal
May repeat 2 depression coma incidence of symptoms in
times at 2-3 or neurological pruitos fetus as well
minutes unresponsivenes as mother
intervals. s of unknown
Pediatric: 0.1 origin
mg/kg to
maximum of
2mg