DISORDER MEDICATIONS

ESOPHAGUS

1. Achalasia Botulinum toxin (botox)

Pneumatic dilation

Heller’s Myatomy
- minimal surgery (incision)
PPI (Proton Pumps Inhibitor)
- zole meds
Calcium channel blockers
 Nitroglycerin
 Amlodipine
 Nicardipine
 Felodipine
 Verapamil HCI
 Diltiazem

2. Hiatal Hernia PPI

H2 (histamine) Receptor blocker

 Cimetidine
 Nizatidine
Antacids
A1 (Oh)3 -aluminum hydroxide
Mg (Oh)2 -Magnesium hydroxide
Ca (Oh)3 -calcium carbonate
A1 (Oh)3 + Mg(Oh)2
Phosphodiesterase

Calcium Channel Blockers

3. Gastroesophageal Reflux Antacids – before meals

Disease (GERD)
H2 receptor antagonist – w/o
regards to meal
PPI – before meals

Mucosal protective meds

 Sucralfate
 Misoprostol
 Mifepristone
Prokinetics
 Metaclopramide
4. Esophageal Cancer Antimetabolites (Adjuvants)
  5-Fluoruoral (5FU)
 Prednisone
 Prednisole

Platinum agent
 Cisplatin
 Carboplatin
 Oxaliplatin

Cytarabine (alkylating syndrome)

-severe vomit
metabolic alkalosis
-MDS(myelodysplastic syndrome)
Proliferation of immature WBC

STOMACH

1. Gastritis Antibiotics
1. Cephalosporins
1st Cefalexin (Keflex)
2nd Cefoxitin
3rd Ceftriaxone (Rocephin)
4th Ceftazidine
5th Cefazoline
2. Antacids
3. H2 receptor blockers
4. PPI
5. Mucosal protective meds
6. Anti-spasmodic / prokinetics

2. Peptic Ulcer Disease (PUD) PPI

H2 receptor blocker
Antacids
Mucosal protective meds
Prokinetics
Cholinergic
Prostaglandins (protection)
Iron supplements
To relieve pain:
Morphine, meperidine, fentanyl

3. Gastric Cancer Chemotherapy

a. Anti-tumor antibiotic
1. Doxorubicin (andriamycin)
2. Mitomycin
b. Antimetabolites
 1. carmustine (BCNN)
2. cisplatin (platinol)

c. Immune therapy
1. rituximab – hypertensive
crisis

INTESTINE

1. Inflammatory Bowel Disease :Delay the progress of disease

(IBD)
1. DMARD’s
(Disease-modifying Anti-
Rheumatic Disease)

Extremely toxic meds:

Immunosuppressants
 Azathioprine
 Cyclosporine
 Cyclophosphamide
 Methotrexate
 Gold salts (nephrotoxic)
 Prednisone (cortico
steroid)
 Methylprednisolone
(spinal chord injury)
2. Antibiotics
 Sulfasalazine
 Trimethoprim
3. Probiotics

4. ADEK supplements

5. Vaccines (TDAP, flu)

(tetanus, diphtheria, pertisus)

2. Irritable Bowel Syndrome :need to treat the symptoms

(IBS)
1. Antispasmodics
 Hyoscine (buscopan)
 TCA’s (antidepressants)
Tricyclic antidepressant
Clomipramine (Tofranil)
Imipramine (Anafranil)
2. Probiotics
- erceflora
 - yakult
3. Sulfasalazine – to relieve
irritability of intestines

3. Appendicitis Management:
Surgery – Appendectomy

4. Peritonitis 1. Antibiotics
 Cephalosporins
1. Cefoxitin
2. ceftazidime
 Aminoglycosides
1. Amikacin
 Vancomycin
 Linezolid

5. Constipation Laxatives
-Irritants
 Bisacodyl
 Caster Oil
-Bulk-formers
 Methylcellulose
-Softeners
 Docusate Na(sodium)
(colace)

6. Colorectal Chemotherapy
 5-fluoruoracil (5FU)
 Capecitabine
 Irinotecan
 Oxaliplatin
side effects: bone marrow
suppression

1. Hepatitis Hep. A
AVOID:
- Aspirin
- Aminoglycosides (-myicin’s med
- Carbonic anhydrase inhibitor
- (acetazolamide)

Hep. B & C
-Universal precautions (means
 gloves daan)

1. Medications:
NO CURE, just to slow down the
progress
 Ritonavir
 Rituximab (to boost
immune system)

2. Liver Cirrhosis 1. Beta-blockers

 propanol
 metoprolol
(Esophageal varies)

2. Antibiotics
 cefoxitin
 neomycin (prevent
reabsorption of urea

3. Diuretics
4. Phospholipids
5. Iron Supplements
6. Coagulating fators
7. Lactulose (precent build up of
anomia in the body
8. Antacids
9. AVOID steroids

3. Hepatocellular Carcinoma Chemotherapy

Arterial-embolization –
medications that are directly
admins to portal vein

 Nitrosoureas (carmustine)
 Platinol (cisplatin)
 Mustard agent
(mechlorethamine)
 Vinblastine
 Cyclophosphamide

PANCREAS

1. Pancreatitis 1. Pain management:

 Opioids (morphine SO4)
 - all except Meperidine
- spasm @ the sphincter
of Oddi

2. Antibiotic Therapy
 Cefoxitin
 Vancomycin

3. Oxygen .via face mask

4. Steroids – to reduce
inflammation

5. H2 receptor blockers

6. Antacids

7. PPI -decrease amount of acid

8. NGT/TPN