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Omeprazole

DRUG CLASSIFICAT DOSE, MECHANISM INDICATION CONTRAINDI SIDE EFFECTS NURSING


NAME ION ROUTE, OF ACTION CATION AND ADVERSE RESPONSIBILITIES
AND REACTION
FREQUENC
Y
Generic Antiulcer, Dose: Suppresses Gastroesophageal Hypersensitivity Side effects: Assess:
Name: proton pump gastric secretion refux disease to this product or
40 mg ● Headache ● GI system: bowel sounds,
Omeprazo inhibitor, by inhibiting (GERD), severe benzimidazoles.
● Dizziness abdomen for pain,
le Benzimidazole hydrogen/potassi erosive
● Asthenia swelling, anorexia, blood
um ATPase esophagitis,
Route: ● Diarrhea in stools, diarrhea, emesis
enzyme system poorly responsive Precautions:
● Abdominal pain ● Clostridium difficile
Brand in gastric parietal systemic GERD, Pregnancy;
IV Infusion ● Vomiting –associated diarrhea
Name: cells; pathologic breastfeeding;
● Nausea (CDAD): assess for fever,
characterized as hypersecretory children; hepatic
Omebloc ● Constipation abdominal pain, bloody
gastric acid pump conditions disease.
Frequency: ● Flatulence stool; may occur up to
inhibitor because (Zollinger-Elliso
● Acid several week after
Q12hrs for 2 it blocks the fnal n syndrome,
regurgitation conclusion of therapy;
days step of acid systemic
● Rash report to the prescriber
production. mastocytosis,
● Back pain immediately
multiple
● Upper ● Electrolyte imbalances:
endocrine
respiratory hyponatremia
adenomas);
infections ● Hepatic enzymes: AST,
treatment of
● Cough ALT, alk phos during
active duodenal
treatment; blood studies:
ulcers
CBC, differential during
with/without
Adverse reaction: treatment, blood dyscrasias
antiinfectives for may occur; vit B12 in
● Hepatic failure
Helicobacter long-term treatment
● Clostridium
pylori ● Fractures: use over 1 yr has
difficile-associat
been associated with
ed diarrhea
fractures
(CDAD)
● Beers: avoid scheduled use
● Pneumonia
>8 wk in patients with
hypersecretory condition,
esophagitis, risk of
Clostridium difficile, and
fractures
● Pregnancy/breastfeeding:
use only if benefits
outweigh fetal risk;
cautious use in
breastfeeding, excreted in
breast milk

Evaluate:
Therapeutic response: absence
of epigastric pain, swelling,
fullness, bleeding; decreased
GERD, esophagitis symptoms

Health teaching:

● To report severe diarrhea;


black, tarry stools;
abdominal cramps/pain; or
continuing headache;
product may have to be
discontinued
● That, if diabetic,
hypoglycemia may occur
● To avoid hazardous
activities because dizziness
may occur
● To avoid alcohol,
salicylates, NSAIDs; may
cause GI irritation
● To take as directed, even if
feeling better; to take
missed dose as soon as
remembered; not to double
● Not to use OTC,
prescription, or herbal
products without
prescriber’s consent
● To take as directed at
lowest dose possible for
shortest time needed
● To report if pregnancy is
planned or suspected or if
breastfeeding

Paracetamol

DRUG CLASSIFIC DOSE, MECHANISM INDICATION CONTRAINDI SIDE EFFECTS NURSING


NAME ATION ROUTE, OF ACTION CATION AND ADVERSE RESPONSIBILITIES
AND REACTION
FREQUENC
Y
Generic Nonopioid Dose: May block pain Mild to Hypersensitivity Side effects: Assess:
Name: analgesic, impulses moderate pain or to this product,
1000 mg ● Anxiety ● For fever and pain: Type
Paracetamol antipyretic, peripherally that fever, arthralgia, phenacetin
● Dyspnea of pain, location, intensity,
nonsalicylate, occur in response dental pain, aspartame,
● Hypertension duration,
paraaminophe to inhibition of dysmenorrhea, saccharin,
Route: ● Hypotension aggravating/alleviating
nol derivative prostaglandin headache, tartrazine.
● Nausea factors; assess for
synthesis; does myalgia,
IV infusion ● Vomiting diaphoresis, fever,
not possess osteoarthritis.
● Abdominal pain baseline and periodically
antiinflammatory Precautions:
● Rash ● Hepatic studies: AST,
properties; Pregnancy,
Frequency: ● Urticaria ALT, bilirubin, creatinine
antipyretic action breastfeeding,
● Injection site before therapy if
Q6hrs X 4 results from geriatric patients,
pain long-term therapy is
doses inhibition of anemia,
anticipated; may cause
prostaglandins in renal/hepatic
hepatic toxicity at doses
the CNS disease, chronic
>4 g/day with chronic use
(hypothalamic alcoholism.
● Renal studies: BUN, urine
heat-regulating
Adverse reaction: creatinine, occult blood,
center).
albumin, if patient is on
● Hepatotoxicity
long-term therapy;
● Hepatic seizures
presence of blood or
(overdose)
albumin indicates
● GI bleeding
● Renal failure nephritis, I and O ratio;
(high, prolonged decreasing output may
doses) indicate renal failure
● Leukopenia (long-term therapy)
● Neutropenia ● Blood studies: CBC, PT if
● Hemolytic patient is on long-term
anemia therapy
(long-term use) ● Chronic poisoning: rapid,
● Thrombocytopen weak pulse; dyspnea; cold,
ia clammy extremities;
● Pancytopenia report immediately to
● Stevens-Johnson prescriber
syndrome ● Potentially fatal
● Toxic epidermal hypersensitivity, allergic
necrolysis reactions: rash, urticaria; if
● Cyanosis these occur, product may
● Anemia have to be discontinued
● Neutropenia ● Stevens-Johnson
● Jaundice syndrome, toxic epidermal
● CNS stimulation necrolysis may occur
during beginning
● Delirium treatment or any other
followed by dose
vascular collapse ● Pregnancy/breastfeeding:
● Seizures cautious use in pregnancy,
● Coma breastfeeding (PO), use
● Death only if clearly needed (IV)

Evaluate:

Therapeutic response:
absence of pain using pain
scoring; absence of fever
Health teaching:

● Not to use with alcohol,


herbals, OTC products
without approval of
prescriber
● To recognize signs of
chronic overdose:
bleeding, bruising,
malaise, fever, sore throat
● That those with diabetes
may notice blood glucose
monitoring changes
● To notify prescriber of
pain or fever lasting more
than 3 days
● Not to be used in patients
<2 yr unless approved by
prescriber
● Hypersensitivity: to stop
product, call prescriber if
rash occurs
● Pregnancy/breastfeeding:
may be used when
breastfeeding, short-term

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