NAME: MIKAELLA ROSARIO

SECTION: BSN1 – B

DRUG STUDY
Diphenhydramine IV
MEDICATIO DOSAGE/ROUTE/ MECHANISM INDICATION CONTRAINDICA SIDE NURSING
N FREQUENCY OF ACTION TION EFFECTS CONSIDERAT
ION
Generic DOSAGE & Contrary to Relieving Usage in General: Prior to
Name: FREQUENCY: cromolyn and histamine- Neonates or Urticaria, drug administration,
diphenhydra nedocromil, induced Premature rash, consider the
mine Moderate Symptoms which also allergy Infants: anaphylactic medication's
hydrochloride ADULT inhibit symptoms, Neonates or shock, aim.
Every four to six hours, as histamine such as preterm photosensitivit
Brand needed, 25 to 50 mg by release, anaphylaxis, newborns should y, excessive Examine
Name: mouth, IM, or IV diphenhydrami seasonal and not use this perspiration, allergies,
Benadryl, 300 mg daily maximum ne instead perennial medication. chills, dryness sleeping
Benadryl orally; 100 mg doses up to competes free allergic of mouth, habits,
Allergy Dye- 400 mg daily IM/IV histamine for rhinitis, and Usage in nose, and coughing, and
Free binding at H1- allergic Breastfeeding throat. lung sounds.
LiquiGels, PEDIATRIC receptor sites. dermatitis. Mothers:
Children's 2 to 5 years: 6.25 mg The actions of Parkinson's Antihistamine Cardiovascul Regularly
Benadryl orally, intramuscularly, or histamine on disease and therapy is not ar System: check
Allergy, intravenously (IM/IV), as H1-receptors drug-induced recommended in Hypotension, the blood
Children's needed; maximum 37.5 in the GI tract, dystonic breastfeeding headache, pressure and
Triaminic mg per day. uterus, major responses. women due to palpitations, compare it to
Thin Strips 6 to 11 years: 12.5 to 25 blood arteries, little sedation the higher risk tachycardia, typical ranges.
Allergy, Alka- mg orally, intravenously, and bronchial at night. to that these extrasystoles. Indicate any
Seltzer Plus or as needed every 4 to 6 muscle are avoid motion medications persistent or
Allergy, hours; maximum 150 mg competitively sickness. provide for Hematologic symptomatic
Nytol, per day. countered by Antitussive newborns in System: blood
PediaCare Use adult dosage if you're diphenhydrami (syrup alone) general and Hemolytic pressure
Children's over 12 years old. ne. Blocking (syrup only). neonates and anemia, drops
Allergy, H1-receptors premature infants thrombocytop (hypotension)
Simply also prevents Together with in particular. enia, or other heart
Sleep, More Severe Symptoms edema, flare- epinephrine agranulocytosi problems
Sominex, ADULT ups, and and other Usage as a s. (palpitations).
QlearQuil Every two to four hours, pruritus from medications, Local
Nighttime as needed, 25-50 mg by developing as diphenhydram Anesthetic: This Nervous Keep an eye
Allergy mouth, IM, or IV a result of ine injection is medication System: on breathing
Relief, 300 mg daily maximum histaminic an shouldn't be used Sedation, both at rest
Tranquil orally; 100 mg doses up to action. antihistamine as a local sleepiness, and while
Nighttime 400 mg daily IM/IV used to treat anesthetic due to dizziness, you're
Sleep Aid, life- the possibility of disturbed exercising.
Unisom PEDIATRIC H1- threatening local necrosis. coordination, Inform the
SleepGels, 2 to 11 years: 1-2 mg/kg antagonists allergic fatigue, doctor if the
Unisom by mouth, IM, or IV every have various responses Antihistamines confusion, patient has
SleepMelts, 2 to 4 hours as necessary; degrees of (anaphylaxis). should not be restlessness, any
ZzzQuil maximum: 300 mg daily anticholinergic When oral used in the excitation, bothersome
by mouth; 100 mg/dose qualities; medication following nervousness, wheezing,
Classificatio up to 400 mg daily IM/IV. ethanolamine cannot be circumstances: tremor, chest or throat
n: Antiemetic Use adult dosage if you derivatives administered, Hypersensitivity irritability, tightness, or
Agents; are 12 or older. have more it is also used to antihistamines insomnia, unusual
Antihistamine anticholinergic to treat the with identical euphoria, bronchial
s, 1st Extrapyramidal activity than symptoms of chemical paresthesia, secretions.
Generation Symptoms other home structures, such blurred vision,
Every six to eight hours as antihistamines allergens, hay as diplopia,
necessary, 25 to 50 mg by , which likely fever, and the diphenhydramine vertigo, Keep track of
mouth, IM, or IV explains common cold. hydrochloride. tinnitus, acute the signs of
100 mg/dose up to 400 diphenhydrami labyrinthitis, seasonal
mg/day IM/IV; maximum ne's Diphenhydra neuritis, allergies
300 mg/day orally antidyskinetic mine, a first- convulsions. (sneezing,
effects. generation rhinitis, itchy
PEDIATRIC Although the antihistamine Gastrointesti eyes, cough)
2 to 11 years: 1 to 2 precise that is nal tract (GI) or allergic skin
mg/kg orally, mechanism is marketed System: reactions
intravenously, or uncertain, the over-the- Epigastric (rash, hives,
parenterally every 6 to 6 antimuscarinic counter, is distress, itching) to
hours as necessary; effect that employed to anorexia, monitor how
maximum: 50 mg/dose up appears to be treat and nausea, well this
to 300 mg/day IM/IV the cause of prevent vomiting, medication
Use adult dosage if you're this dystonias, diarrhea, treats these
over 12 years old. anticholinergic sleeplessness constipation. conditions.
action may , pruritis,
Insomnia (Short also be the urticaria, Genitourinar Examine the
Medication) cause of its vertigo, and y System: frequency and
Depending on necessity, antiemetic motion Urinary kind of
take 25 to 50 mg by properties. sickness frequency, coughing, the
mouth 30 minutes before Diphenhydram among other difficult sound of the
bed. ine directly ailments. For urination, lungs, the
Children aged 12 years suppresses patients who urinary quantity and
and older: Take 25 to 50 the cough have allergies retention, type of sputum
mg by mouth at bedtime center and to other, more early menses. produced, and
as necessary; begin 30 induces widely used lung sounds if
minutes before bedtime. sedation by local Respiratory a cough
depressing the anesthetics, it System: suppressor
Motion Sickness central also has local Thickening of has been
Prevention nervous anesthetic bronchial used. Identify
Every four to six hours, as system. qualities; secretions, whether this
needed, 25 to 50 mg by Topical nevertheless, tightness of medication
mouth, IM, or IV. diphenhydrami this is an off- chest or throat suppresses
Start 30 minutes before ne gives label usage of and wheezing, coughs well.
the event; take 300 mg temporary the drug. Oral nasal
maximum daily by mouth; relief from mucositis stuffiness. Assess the
100 mg maximum daily by insect bites, therapy is patient's motor
IM/IV mild burns, another non- function if a
sunburn, or approved medicine is
CHILDREN'S DOSAGE: minor usage. being used to
2 to 5 years: 6.25 mg abrasions. treat
orally, intramuscularly, or This effect Parkinson's
intravenously every 4 to 6 may be disease,
hours as necessary; begin caused by a especially
30 minutes before the diminished when
event; maximum 37.5 mg anesthetic commencing
per day. effect brought drug therapy,
6 to 11 years: 12.5 to 25 on by the changing the
mg orally, intramuscularly, nerve cell dosage, or
or IV every 4 to 6 hours as membranes' adding other
necessary; begin 30 decreased anti-Parkinson
minutes before the event; permeability to drugs. Motor
maximum 150 mg per sodium ions function
day. (preventing should be
Use adult dosage if you're the evaluated
over 12 years old. transmission throughout the
of nerve day at various
Pruritis/Urticaria impulses). times,
Every four to six hours, as Tolerance to including
needed, 25 to 50 mg by diphenhydrami when
mouth, IM, or IV. 100 ne may medicines are
mg/dose up to 400 develop after at their peak
mg/day IM/IV; maximum repeated use, therapeutic
300 mg/day orally. but the levels (i.e., 2-4
diminished hours after
PEDIATRIC sedative oral dose) and
2 to 5 years: 6.25 mg effects may when their
orally, intramuscularly, or make this effects are the
intravenously (IM/IV), as advantageous. least
needed; maximum 37.5 noticeable
mg per day. Although it has (just before
6 to 11 years: 12.5 to 25 additional the next
mg orally, intravenously, modes of dose).
or as needed every 4 to 6 action,
hours; maximum 150 mg diphenhydrami Assess for
per day. ne primarily evidence of
Use adult dosage if you're inhibits the H1 successful
over 12 years old. (histamine 1) treatment
receptor. while treating
Sedation Diphenhydram anaphylaxis,
Every four to six hours, as ine reverses such as
needed, 25 to 50 mg by the effects of diminished
mouth, IM, or IV. 100 histamine on skin reactions
mg/dose up to 400 capillaries by (rash,
mg/day IM/IV; maximum acting as an urticaria),
300 mg/day orally inverse enhanced
Pruritis/Urticaria agonist at the airway
(Topical Medication) H1 receptor, patency, and
(Topical Treatment) which lessens improved
Administer up to four allergic ventilation
times per day, as needed. reaction (decreased
symptoms. dyspnea,
Regarding local Muscarinic wheezing,
anesthesia receptors and shortness of
 Make a the H1 breath).
diphenhydramine receptor share
1% solution (10 similarities. Examine any
mg/mL). Diphenhydram drowsiness
 Take up all of the ine is used as and dizziness
50 mg/mL an that may
diphenhydramine antiparkinson impair
in a vial's contents drug since it balance,
into a 10 mL also functions walking, and
syringe. This as an other
needs to have a 1 antimuscarinic functional
mL volume. because it is a activities.
 To get a final competitive Inform the
volume of 5 mL, antagonist of doctor of any
dilute the syringe's the muscarinic balance
contents with four acetylcholine issues and
mL of 0.9% receptor. functional
sodium chloride. Finally, limits, and
Now it contains 10 diphenhydrami advise the
mg/mL of ne exhibits patient's
diphenhydramine local caregivers and
1%.[3][4] anesthetic family
 This use is not characteristics members to
authorized. through be cautious.
 Track down any blocking
tissue necrosis. intracellular
 sodium
channels.
ROUTE:
Diphenhydramine may be
administered topically,
intramuscularly,
intravenously, or as a pill,
capsule, or solution for
oral administration.

References:
Benadryl, Nytol (diphenhydramine) dosing, indications, interactions, adverse effects, and more. (n.d.).
https://reference.medscape.com/drug/benadryl-nytol-diphenhydramine-343392#:~:text=Benadryl%2C%20Nytol
%20(diphenhydramine)%20dosing,interactions%2C%20adverse%20effects%2C%20and%20more

Diphenhydramine (Benadryl) Nursing Considerations | NRSNG Nursing Course. (n.d.). NURSING.com.

https://nursing.com/lesson/drug-diphenhydramine-benadryl

Diphenhydramine | Davis’s Drug Guide for Rehabilitation Professionals | F.A. Davis PT Collection | McGraw Hill Medical. (n.d.).
https://fadavispt.mhmedical.com/content.aspx?bookid=1873§ionid=139008625#:~:text=Report%20a%20sustained%20or
%20symptomatic,chest%2C%20or%20abnormal%20bro nchial%20secretions.

Sicari, V. (2022, July 11). Diphenhydramine. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK526010/