Mindanao State University – Iligan Institute of Technology Student: ___Dannah S.

Bullianday______________________
COLLEGE OF NURSING Section:_____B______

DRUG STUDY

Brand Name: Biogesic___________________ Generic Name: Paracetamol Drug Classification: Therapeutic: antipyretics, nonopioid analgesics

Dosage, Route & Frequency Adverse

Drug-Drug & Drug- Side Effects
Prescri Drug Action Indications Contraindications Reactions (By
Recommended Food Interactions (By System)
bed System)
PO (Adults and Children > 12 yr): 650 mg Inhibits the synthesis of Drugs that alter gastric Previous GI: Hepatotoxicity (increased Hepatotoxicity
325–650 mg A q 4–6 hr or 1 g 3–4 tablet PO prostaglandins that may serve emptying can hypersensitivity; doses), increased liver Rash
times daily or 1300 mg q 8 hr (not TID as mediators of pain and alter paracetamol pharma Treatment of mild Products containing enzymes, Urticaria (Hives)
pain, fever. Constipation
to exceed 4 g or 2.5 g/24 hr in fever, primarily in the CNS. cokinetics, but this does alcohol, aspartame, GU: renal failure (high
patients with hepatic/renal Has no significant anti- not result in toxicity in saccharin, sugar, or doses/chronic use).
impairment). inflammatory properties or GI therapeutic use. tartrazine (FDC yellow Hemat: neutropenia,
toxicity. Therapeutic Effects: dye #5) should be pancytopenia.
Analgesia. Antipyresis. avoided in patients who Derm: rash, urticaria.
have hypersensitivity or
Absorption: Well absorbed intolerance to these
following oral administration. compounds; Severe
Distribution: Widely hepatic
distributed. Crosses the impairment/active liver
placenta; enters breast milk in disease.
low concentrations.
Metabolism and Excretion:
85–95% metabolized by the
liver (CYP2E1 enzyme
system). Metabolites may be
toxic in overdose situation.
Metabolites excreted by the
kidneys.
Half-life: 1–3 hr.
TIME/ACTION PROFILE
(analgesia and antipyresis)
ROUTE: PO
ONSET: 0.5–1 hr
PEAK: 1–3 hr
DURATION: 3–8 hr

Responsibilities in the Nursing Process (ADPIE) Responsibilities in the Nursing Process (ADPIE)
Assessment: Potential Nursing Diagnoses:
● Acute pain
o Assess overall health status and alcohol usage before administering acetaminophen. Patients who
are malnourished or chronically abuse alcohol are at higher risk of developing hepatotoxicity with Implementation
chronic use of usual doses of this drug.
o Assess amount, frequency, and type of drugs taken in patients self-medicating, especially with o Implement appropriate manual therapy techniques, physical agents, and therapeutic exercises to
OTC drugs. Prolonged use of acetaminophen increases the risk of adverse renal effects. For reduce pain and decrease the need for acetaminophen and other analgesics.
short-term use, combined doses of acetaminophen and salicylates should not exceed the o Help patient explore other nonpharmacologic methods to reduce chronic pain, such as relaxation
recommended dose of either drug given alone. techniques, exercise, counseling, and so forth.
o Pain: Assess type, location, and intensity prior to and 30–60 min following administration.
o Fever: Assess fever; note presence of associated signs (diaphoresis, tachycardia, and malaise).
o Toxicity and Overdose: If overdose occurs, acetylcysteine (Acetadote) is the antidote.