Figure 7.

Androgen-mediated hair follicle [27]

References

24. Trüeb, R.M.J.S.a.d., Further clinical evidence for the effect of IGF-1 on
hair growth and alopecia. 2018. 4(2): p. 90-95.

25. Tazdanian, N., S. Mozafarpoor, and A.J.D.T. Goodarzi, Phosphodiesterase

inhibitors and prostaglandin analogues in dermatology: A comprehensive
review. 2021. 34(1): p. e14669.

26. Miranda, B.H., et al., Androgens trigger different growth responses in

genetically identical human hair follicles in organ culture that reflect their
epigenetic diversity in life. Faseb j, 2018. 32(2): p. 795-806.

27. Yip, L. and R. Sinclair, Antiandrogen therapy for androgenetic alopecia.

Expert Review of Dermatology, 2006. 1: p. 261-269.

(10): 01:15:46 Topical Caffeine & Slowing Hair Loss

Another significant chemical that has the potential to promote hair growth is
caffeine, a stimulant that is commonly consumed. In addition to its effects on
the nervous system, caffeine has been found to have various other properties.
This substance exhibits considerable potency as a phosphodiesterase (PDE)
inhibitor. Its PDE inhibitory properties indirectly promote the stimulation of
insulin-like growth factor 1 (IGF-1), as PDE has been shown to suppress
IGF-1. The consumption of caffeine or the application of topical caffeine
ointment has been observed to effectively inhibit PDE, thereby leading to an