Unit XI The Nervous System: C.

Motor and Integrative Neurophysiology

94. A 67-year-old man has a stroke. One week later, he 100. Bilateral lesions involving the ventromedial hypothala-
experiences sudden and uncontrolled flailing, ballistic mus will lead to which of the following deficits?
movements of his limbs. Which part of the man’s brain A) Decreased eating and drinking
is most likely to have been damaged by the stroke? B) Loss of sexual drive

UNIT XI
A) Globus pallidus C) Excessive eating, rage and aggression, hyperactivity
B) Lateral hypothalamus D) Uterine contractility, mammary gland enlargement
C) Red nucleus E) Obsessive compulsive disorder
D) Subthalamic nucleus
E) Ventrobasal complex of thalamus 101. Under awake, resting conditions, brain metabolism ac-
counts for about 15 percent of the total metabolism of
95. A physiology experiment is conducted in which a test the body; this rate is among the highest metabolic rates
dose of norepinephrine is administered intravenously to of all tissues in the body. Which cellular population of
the front limbs of rats, causing a 25 percent reduction in the nervous system contributes most substantially to
blood flow to the front limbs compared with basal val- this high rate of metabolism?
ues. Next, the stellate ganglion is removed. Three days A) Astrocytes
later the same dose of norepinephrine is administered B) Neurons
intravenously. Which option best describes the most C) Ependymal cells
likely change in front limb blood flow (compared with D) Choroid plexus cells
basal values) within 30 minutes after norepinephrine is E) Brain endothelial cells
administered to the ganglionectomized rats?
A) 25 percent increase 102. Which structure(s) in the cerebellum has/have a topo-
B) 25 percent reduction graphical representation of the body?
C) 5 percent increase A) Dentate nucleus
D) 5 percent reduction B) Lateral hemispheres
E) 75 percent increase C) Flocculonodular lobe
F) 75 percent reduction D) Vermis and intermediate hemisphere
E) Cerebellar peduncle
96. In an otherwise normal person, dysfunction of which
brain area will lead to behavior that is not appropriate 103. Which structure is an important pathway for commu-
for the given social occasion? nication between the limbic system and the brain stem?
A) Ventromedial nuclei of hypothalamus A) Mamillothalamic tract
B) Amygdala B) Fornix
C) Corpus callosum C) Anterior commissure
D) Fornix D) Indusium griseum
E) Uncus E) Medial forebrain bundle

97. The function of which organ or system is dominated by 104. A 75-year-old woman is taken to the physician be-
the sympathetic nervous system? cause of worsening forgetfulness. She has trouble
A) Systemic blood vessels playing cards with her friends because she cannot re-
B) Heart member what game is being played. She recently got
C) Gastrointestinal gland secretion lost during a walk in the neighborhood she has lived
D) Salivary glands in for 35 years. Which substance is most likely to be
E) Gastrointestinal motility increased in the brain of this woman?
A) alpha-1 antitrypsin
98 Schizophrenia is thought to be caused in part by excessive B) alpha-amylase
production and release of which neurotransmitter agent? C) beta-amyloid peptide
A) Norepinephrine D) beta-endorphin
B) Serotonin E) gamma-glutamyl hydrolase
C) Acetylcholine F) gamma-glutamyl transferase
D) Substance P
E) Dopamine 105. Which of the following best describes the cerebellar
deficit in which there is a failure to perform rapid al-
99. Stimulation of which subcortical area can lead to con- ternating movements indicating a failure of “progres-
traction of a single muscle or small groups of muscles? sion” from one part of the movement to the next?
A) Dentate nucleus of the cerebellum A) Past-pointing
B) Ventrobasal complex of the thalamus B) Intention tremor
C) Red nucleus C) Dysarthria
D) Subthalamic nucleus D) Cerebellar nystagmus
E) Nucleus accumbens E) Dysdiadochokinesia
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