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BenchTop Pro with Omnitronics

The VirTis BenchTop Pro freeze dryers have
been designed to meet the needs of the most
demanding research laboratories. Each
system can be configured to accommodate
present and future requirements. Condenser
refrigeration packages of -55°C, -75°C,
-85°C and -105°C can meet the demands
of both aqueous or aqueous-solvent based
formulations.

You can configure your system

to run just a few samples or
to process a relatively heavy
load with condenser size
choices of 3 liter, 8 liter or
9 liter. Selecting a size and
temperature configuration
allows you to maximize the use
of the freeze dryer in your lab
while not paying needlessly
for unnecessary capacity or
refrigeration.

Each system can be

configured to meet
the needs of the most
demanding research
laboratories.

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Manifolds
Manifolds are available in a variety
of styles and are designed to be
interchangeable. There are a number of
considerations when selecting a manifold.
In a multi-user lab it is often best to utilize
a robust stainless steel manifold. In
applications where inorganic solvents are
being utilized or you are rack drying and
want to ensure visibility an acrylic manifold
would be preferred. In applications
with organic solvents the stainless steel
manifolds will provide long lasting use.

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Omnitronics Controller
The Omnitronics Controller simplifies freeze drying
and makes the system easy to operate. One touch
start up and shut down ensure that your product
and freeze dryer are protected from inappropriate
procedures. The graphic display provides at-a-
glance understanding of the status of the freeze
dryer and whether or not appropriate freeze drying
conditions exist. Audible alarms help notify the
user of potential problems with the system and
hence, with the product. All Omnitronics controllers
come complete with a trending screen that allows
you to watch critical parameters on an on-going
basis if required. Utilizing the optional Ethernet
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control, you can connect the freeze dryer to your
company’s or institution’s network, and monitor
and/or control your freeze dryer from any other
location on the network. The Ethernet option
also allows print out in a batch record, alpha-
numeric, type report.
One touch start up and shut
down ensure that your product
and freeze dryer are protected
from inappropriate procedures.
Don’t waste time with
slow & messy defrosting

The hot gas defrost in the BenchTop Pro

allows for fast turnaround time and helps
minimize clean up efforts when having
to pour warm water into a condenser. In
addition, corrosive solvents which are more
active at ambient and higher temperatures
will spend a minimum amount of dwell time
in the condenser with fast hot gas defrost—
no need to wait overnight to drain the
system.

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 VirTis/SP Scientific supports your freeze drying endeavors with a team of technically
qualified associates who can help you choose the right system and provide you with
helpful application tips. In addition, SP Scientific provides the globally recognized
LyoLearn Webinar series. These are free webinars, provided by industry experts on topics
of interest to the freeze drying community. Our technical papers and application notes
can be downloaded from our website at your convenience and are designed to help you
get the most out of your freeze dryer.

Standard Omnitronics Omnitronics with

Ethernet Option
• High performance PLC controller
• Easy to use interface provided by full color • Control and/or monitor your system from
touch screen navigation. anywhere on your network
• Ensure a longer lifetime for your freeze dryer • Enable the freeze dryer to email you if
by avoiding utility degradation conditions there is a process alert/alarm
such as high ambient and low voltage with • Full reporting capabilities with batch
alert notifications reports that can be exported to Windows
• Real time graphical screen data logging to Excel®
review system parameters during a run • Optional remote service support by
• Help protect your product from unfavorable allowing our qualified technicians to
conditions with “out of range” and “in access your system
range” for freeze drying indicators
• Save time with one button start-up and one
button shut-down
• Stores years of data on micro memory card
• Set point control with automatic PID tuning
• Precise alpha-numeric display of setting and
read-out temperatures
• Currently available in English, Spanish,
German & French. Other languages may be
available on request.
• User selectable pressure in millibars, millitor
or pascals. Temperature in °C or °F

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 Features of the BenchTop Pro
• Condensers of 3, 8 and 9 liters in a bench top
footprint
• Refrigeration packages for maximum low
temperature of -55°, -75°, -85° or -105°C
• One touch start-up and shut-down
• Pressure control to avoid back-streaming or for
faster freeze drying
• A variety of manifolds to accommodate most
processing configurations
• Rugged and reliable Pirani vacuum sensor
• Hot gas defrost in approximately 10 minutes or
less
• Optional vacuum pump isolation valve

Selection Guide
There are two main criteria for selecting the benchtop freeze dryer that is right for
you. The first is determining what condenser capacity you need in between defrost
cycles. The second is to determine what solvents you may be using in your process.
When utilizing water as the only solvent the highest condenser temperature offered is
appropriate. In cases where organic or inorganic solvents are being utilized as part
of the solvent matrix the lowest temperature condenser is always preferred.
Load Capacity Vacuum Pump
Manifold Material Choice
Solvents 3 Liter 8 Liter 9 Liter Considerations
Standard oil sealed, rotary vane direct
Water ES (-55°C) XL (-75°C) ES (-55°C) Acrylic or stainless steel. Multiple user labs may drive pump. When working in low
have better experience with stainless steel. pressure conditions consider a dry scroll
pump if oil backstreaming is a concern.

Water and inorganic solvents XL (-75°C) ZL (-105°C) EL (-85°C) Maximize use of acrylic and minimize use of Standard pump with corrosion resistant
stainless steel. oil or combination standard pump with
diaphragm pump.

Water & organic solvents XL (-75°C) ZL (-105°C) EL (-85°C) Maximize use of stainless steel and minimize Standard pump with corrosion resistant
use of acrylic if possible. oil or combination standard pump with
diaphragm pump.

Water & both organic and inor- XL (-75°C) ZL (-105°C) EL (-85°C) Maximize use of acrylic if higher in organic Combination standard pump with
solvents. Maximize use of stainless steel if diagphragm pump.
ganic solvents higher in organic solvents.

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BenchTop Pro with
Omnitronics
3L Freeze Dryer
The BenchTop Pro with Omnitronics
3 Liter system is designed as
a personal freeze dryer or for
small laboratories processing less
product at any one time. This unit
is available with all of the manifold
choices that can be used on the BenchTop Pro with Omnitronics 3 Liter Freeze Dryer
larger benchtop system giving it the Condenser blank off (no load) ES -55°C (-52°C for 50Hz) / XL -75°C
temperature (-72°C for 50Hz)
same flexibility and performance.
Condenser capacity in 24 hours Approximately 2 Liters
(water, heaviest load)
• Condenser temperature option of
-55°C (-52°C for 50Hz) or -75°C Overall condenser capacity 3 Liters

(-72°C for 50Hz) Omnitronics control

• CFC free refrigerants * Vacuum indication in millitor, Atmospheric to 1 mT

microbar or pascals (user selectable)
• Overall condenser capacity of 3
* Temperature indication in °C or °F "T" type thermocouples
liters (user selectable)
• Approximate 24 hour rating of 2 * Voltage and ambient temperature Alarms if out of acceptable range for
liters/24 hour (extreme pressure indicators system
and temperature, water only)* * Communication ports Ethernet connection
• Omnitronics Control for monitoring Defrost Method Hot gas
critical freeze drying parameters System refrigerant CFC free
and for vacuum control Condenser type Smooth wall interior with bottom external
• Remote control, batch reporting coil
and emailed alarms with Ethernet Compressor(s) ES is 1/3 HP, XL is 3/8 HP
interface Average time for pull down to 100 mT 15 minutes
• Fast turnaround time with hot gas Ultimate system vacuum with manifold 20 mT
defrost and smooth condenser walls Base cabinet dimensions W x D x H 15.5in x 28.5in x 17in (39.4cm x
72.4cm x 43.2cm)
• Alarms for out-of-range conditions
Weight 60 lbs (27.3 kg)
*The 24 hour rating is not reproducible (unpackaged and without manifold)
in the lab with product. This rating is to Standard Voltages 100-120V 50/60Hz, 200-240V
illustrate the efficiency of the refrigeration 50Hz/208-230V 60Hz
design from one system to another. It is
based on loading as much water onto the Manifold and Vacuum Pumps Sold Separately
freeze dryer in 24 hours as possible with
equipment not typically used in freeze - See Accessories
drying applications
Current as of May 2013; Specifications are subject to change
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BenchTop Pro with
Omnitronics
8L Freeze Dryer
The BenchTop Pro with Omnitronics
8 liter is designed for heavier loads
and for use with solvents other than
water. It is available with a -75°C
or -105°C condenser. The -105°C
option is preferred for applications
involving low freezing point solvents
such as TFA, acetronitrile and
alcohols. Even if the freezing point BenchTop Pro with Omnitronics 8 Liter Freeze Dryer
of your solvent is below -105°C this Condenser blank off (no load) XL -75°C (-72°C for 50Hz) /ZL
temperature condenser is more likely temperature -105°C (-102°C for 50Hz)
to liquefy the solvent and thus prevent Condenser capacity in 24 hours Approximately 3 Liters
it from migrating easily to the vacuum (water, heaviest load)
pump. Overall condenser capacity 8 Liters
Omnitronics control
* Vacuum indication in millitor, microbar Atmospheric to 1 mT
• Offered in low and ultra-low condenser
or pascals (user selectable)
configuration -75°C (-72°C for 50Hz)
* Temperature indication in °C or °F "T" type thermocouples
or -105°C (-102°C for 50Hz) (user selectable)
• CFC free refrigerants * Voltage and ambient temperature Alarms if out of acceptable range for
• Condenser capacity total of 8 liters indicators system
• Approximate 24 hour rating of 3 * Communication ports Ethernet connection
liters/24 hours (extreme pressure and Defrost Method Hot gas
temperature, water only)* System refrigerant CFC free
• Omnitronics Control for monitoring Condenser type Smooth wall interior with bottom
critical freeze drying parameters and external coil

for vacuum control Compressor(s) XL is 3/8 HP, ZL is 1/3 HP and 3/8

HP
• Remote control, batch reporting and
Average time for pull down to 100 mT 18 minutes
emailed alarms with Ethernet interface
Ultimate system vacuum with manifold 20 mT
• Fast turn around with hot gas defrost.
Base cabinet dimensions W x D x H 15.5in x 28.5in x 17in (39.4cm x
• Alarms for out-of range-conditions 72.4cm x 43.2cm)
Weight 131 lbs (59.4 kg)
*The 24 hour rating is not reproducible in the
(unpackaged and without manifold)
lab with product. This rating is to illustrate
the efficiency of the refrigeration design Standard Voltages 100-120V 50/60Hz, 200-240V
from one system to another. It is based on 50Hz/208-230V 60Hz
loading as much water onto the freeze dryer Manifold and Vacuum Pumps Sold Separately
in 24 hours as possible with equipment not - See Accessories
typically used in freeze drying applications

Current as of May 2013; Specifications are subject to change

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BenchTop Pro with
Omnitronics
9 Liter
The BenchTop Pro with Omnitronics
9 liter is the high capacity
workhorse of the bench top freeze
dryer product family. Built for labs
that require greater throughput and
freeze drying availability, for some
BenchTop Pro with Omnitronics 9 Liter Freeze Dryer
labs it will handle their weekly
requirements without shut down Condenser blank off (no load) ES -55°C (-52°C for 50Hz) /EL -85°C
temperature (-82°C for 50Hz)
and defrost. It is available with a
-55°C or -85°C condenser Condenser capacity in 24 hours (water, Approximately 5 Liters
heaviest load)

• Offered in low and ultra-low Overall condenser capacity 9 Liters

condenser configuration -55°C Omnitronics control

(-52°C for 50Hz) or -85°C (-85°C * Vacuum indication in millitor, microbar Atmospheric to 1 mT
or pascals (user selectable)
for 50Hz)
* Temperature indication in °C or °F "T" type thermocouples
• CFC free refrigerants (user selectable)
• Condenser capacity total of 9 liters * Voltage and ambient temperature Alarms if out of acceptable range for
• Approximate 24 hour rating of 5 indicators system
liters/24 hours (extreme pressure * Communication ports Ethernet connection
and temperature, water only)* Defrost Method Hot gas
• Omnitronics Control for monitoring System refrigerant CFC free
critical freeze drying parameters Condenser type Internal Coil
and for vacuum control Compressor(s) ES is 1/3 HP, EL is 1/3 HP and 3/8
• Remote control, batch reporting HP
and emailed alarms with Ethernet Average time for pull down to 100 mT 18 minutes
interface Ultimate system vacuum with manifold 20 mT
• Fast turn around with hot gas Base cabinet dimensions W x D x H 15.5in x 28.5in x 17in (39.4cm x
72.4cm x 43.2cm)
defrost.
Weight (lb/kg) 131 lbs (59.4 kg)
• Alarms for out-of range-conditions
(unpackaged and without manifold)

*The 24 hour rating is not reproducible Standard Voltages 100-120V 50/60Hz, 200-240V
in the lab with product. This rating is to 50Hz/208-230V 60Hz
illustrate the efficiency of the refrigeration
design from one system to another. It is
based on loading as much water onto the Manifold and Vacuum Pumps Sold Separately
freeze dryer in 24 hours as possible with - See Accessories
equipment not typically used in freeze
drying applications
Current as of May 2013; Specifications are subject to change

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Accessories for the BenchTop Pro
Tree or “T” type Manifolds
Available in 8 or 12 port configuration. 316 Stainless steel complete with Quick
Seal Valves and built in adaptor plate.

Part Number Description Dimensions

BTP-MST-08 Stainless steel manifold, 8 HEIGHT 19.25” (48.9 CM),
LENGTH 15” (38.1 CM), WIDTH
ports 15.25” (38.74 CM)

BTP-MST-12 Stainless steel manifold, 12 HEIGHT 19.25” (48.9 CM),

LENGTH 15” (38.1 CM), WIDTH
ports 23” (58.42 CM)

Condensate Drip Pan Kit for Tree of “T” Type Manifolds

This condensate drip pan kit will provide support for flasks on the Tree manifold
and also collect condensate as it drips off the outside of the product containers
during freeze drying.

Part Number Description

CPK Stainless steel flask support with plastic trays

Condensate Drip Pan Kit for Tree of “T” Type Manifolds

This condensate drip pan kit will provide support for flasks on the Tree
manifold and also collect condensate as it drips off the outside of the product
containers during freeze drying.

Part Number Description

CPK Stainless steel flask support
with plastic trays

Vertical Manifold
Available in 12 port configuration. 316 stainless steel complete with Quick Seal
Valves and built in adaptor plate.

Part Number Description Dimensions

BTP-MSV-12 Stainless steel manifold, 12 HEIGHT 16.25” (41.28 CM),
ports LENGTH 15” (38.1 CM), WIDTH
15” (38.1 CM)

Part Number Description

CPK Stainless steel flask support with plastic trays

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 Drum Manifolds

Classic drum type manifolds are available in both stainless steel and acrylic
configuration. Comes complete with condenser adaptor plate of same material.
Accessory racks can be coupled with these manifolds for rack drying—either heated or
unheated.

Part Number Description Dimensions

BTP-DA-08-0 8 port acrylic drum manifold DRUM - HEIGHT 12.25” (31.12 CM) ID 14.25”
(36.2 CM) OD, WIDTH Ø9” (22.86 CM) ID,
Ø9.5” (24.13 CM) OD
ADAPTER PLATE – HEIGHT 1” (2.54 CM),
WIDTH Ø15” (38.1 CM)
OVERALL ASSEMBLY – HEIGHT 15” (38.1 CM),
WIDTH Ø18” (45.72 CM) WITH QUICK SEAL
VALVES INSTALLED

BTP-DA-12-0 12 port acrylic drum manifold DRUM – HEIGHT 16.25” (41.28 CM) ID, 18”
(45.72 CM) OD, WIDTH Ø11.5” (29.21 CM)
ID, Ø 12” (30.48 CM) OD
ADAPTER PLATE – HEIGHT 1” (2.54 CM),
WIDTH Ø15” (38.1 CM),
OVERALL ASSEMBLY – HEIGHT 18.75”, WIDTH
Ø20.5” (52.07 CM) WITH QUICK SEAL VALVES
INSTALLED

BTP-DA-12-H 12 port acrylic drum manifold
for use with heated racks
DRUM - HEIGHT 16.25” (41.28 CM) ID, 18”
(45.72 CM) OD, WIDTH Ø11.5” (29.21 CM)
ID, Ø12” (30.48 CM) OD
ADAPTER PLATE - HEIGHT 1.5” (3.81 CM),
WIDTH Ø15” (38.1 CM)
OVERALL ASSEMBLY – HEIGHT 19.25”, WIDTH
Ø20.5” (52.07) WITH QUICK SEAL VALVES
INSTALLED

BTP-DS-18-0 18 port stainless steel drum DRUM - HEIGHT 13” (33.02 CM) ID, 13.25”
manifold (33.66 CM) OD, WIDTH Ø12” (30.48 CM) ID,
Ø13” (33.02 CM) OD
SST ADAPTER PLATE – HEIGHT 0.25” (0.64
CM), WIDTH Ø15” (38.1 CM)
ACRYLIC COVER – HEIGHT 0.75” (1.91 CM),
WIDTH Ø13.5” (34.29)
OVERALL ASSEMBLY – HEIGHT 14.25” (36.2
CM), WIDTH Ø21” (Ø53.34 CM) WITH QUICK
SEAL VALVES INSTALLED

Drum Manifold Racks
Racks are constructed of 304 stainless steel and adjustable.

Part Number Description Dimensions

BR-3U-08 3 tiered rack for BTP-DA-08 HEIGHT 10.5” (26.67 CM), WIDTH Ø8.5
(21.59 CM), SPACING 3.50” (8.89 CM)

BR-3U-12 3 tiered rack for BTP-DA-12 HEIGHT 14.5” (36.83 CM), WIDTH Ø10.5
(26.67 CM), SPACING 4.75” (12.07 CM)

BR-3U-18 3 tiered rack for BTP-DA-18 HEIGHT 12” (30.48 CM), WIDTH Ø10.5
(26.67 CM), SPACING 3.75” (9.53 CM)

BR-3H-13 3 tiered rack for BTP-DA-12 with HEIGHT 12” (30.48 CM), WIDTH Ø8.5 (21.59
on off heater CM), SPACING 4.75” (12.07 CM)

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 Wide Mouth Filter Seal Flasks
These borosilicate flasks are specially designed for manifold freeze drying. The flat
bottom makes it easy to stabilize the flask in its upright position for “plug” or static
freezing. The wide mouth of the flask makes it easier to place product in the flask and
perhaps even more importantly, remove product from the flask. The snap on silicone top
ensures a good vacuum seal and comes complete with a filter to eliminate the possibility
of cross contamination when several flasks are on the same dryer. All components can
be autoclaved. The flask itself is available in regular and in safety coated configurations.
Must be used with manifold adaptors.

Regular Flask Safety Coated Maximum Maximum

Part Number Part Number Capacity Fill
235390 312892 40 ml 20 ml
235382 312900 75 ml 35 ml
118174 312918 150 ml 75 ml
118208 312918 300 ml 150 ml
118232 312934 600 ml 300 ml
118273 312942 1200 ml 600 ml

118307 312959 2000 ml 1000 ml

Manifold Adaptors

Part Number Material Shape Port Size Compatible

Flasks
367424 Plastic Straight Barb ¾” 150 – 2000 ml
179655 Glass Straight ¾” 150 – 2000 ml
177923 Stainless steel Straight ¾” 150 – 2000 ml
177899 Glass 45 degree ¾” 150 – 2000 ml
177931 Stainless steel 45 degree ¾” 150 – 2000 ml
179622 Glass Straight ¾” 40 & 75 ml
177873 Glass 45 degree ¾” 40 & 75 ml

Don’t see the adaptor you need? Please inquire.

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 Ampule Adaptor
Designed to hold 19 ampule type containers on a single valve

Part Number Description

413534 19 port ampule adaptor

We also carry a full line of sealing torches and ampules. Please inquire.

Container System

Two container systems are offered. One for bulk and one for stoppering
applications. Containers are made of 304 SS and are attached to your
manifold with vacuum tubing for processing in bulk or in vials.

Part Number Description Dimensions

438032 Bulk ss container
SC-1 Small stoppering container 7 – 5 ml vials, 5 – 10 ml vials,
4 – 30 ml vials, 1 – 100 ml vial

Vacuum Pumps

VirTis/SP Scientific is pleased to offer a full line of vacuum pumps to solve

any application need. Included in our offering are the standard two stage,
oil sealed rotary direct drive vacuum pumps as well as dry scroll type
pumps and combination pumps that are joining of the standard pump with
a diaphragm pump for service in highly corrosive environments.

Vacuum
Foreline Traps Part Number Description
FTA Filter trap housing, insert
purchased separately
These traps are designed to
help prevent the migration of FTA-SS Soda sorb insert for acid applications
contaminants to the vacuum FTA-AC Activated charcoal insert for organic solvent appli-
cations
pump or to minimize vacuum
pump oil back-streaming. FTA-MS Molecular sieve insert for water vapor and to help
minimize oil backstreaming
They are placed in the
vacuum line between the
freeze dryer and the vacuum
pump.

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SP Scientific Supports You in Ways Unrivaled in the Industry:

LyoLearn Webinars:
Free online seminar series featuring topics of interest to lyophilization scientists and
presented by industry experts. Live sessions allow participants to interact with renowned
freeze-drying specialists, such as Dr. John Carpenter, Dr. Steve Nail, Dr. Michael Pikal,
and other who’s who of the freeze drying community. Each online LyoLearn Session is
recorded and archived for future viewing.

Hands-On Training:
SP Scientific’s hands-on training courses offer attendees the chance to optimize their
learning experiences by using tangible applications in a controlled setting. Led by “go-to”
leaders in the lyophilization industry, these courses are a must for anyone getting started
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ideas and theories.

Technical Briefs:
SP Scientific’s technical briefs are relevant papers covering in-demand topics. Available
in a variety of languages, titles include: The Relevance of Product Resistance in Primary
Drying, The Importance of Controlling Nucleation Temperature During the Freeze Step,
Case Studies in Diagnosing and Correcting Problematic Lyophilization Cycles and/or
Formulations, Basic Principles of Freeze Drying, and Basic Lyophilizer Maintenance Helps
to Assure Good Results.

All of this is available on our website

www.SPScientific.com.
Logon to learn more!

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