ene ? Amines Chass 1) Dhrines axe He allyl Jaxyl doxiva Axe pom the x. Ute a oe 4 ee ee alarms of Qrmmonia verte Cle by - Oe argh groups Na, tS Rn One Oe wee canine ALiphatie arnine NH > AR-NH ne ae Qeomabe amine a. Avntned —? &) Onthe bas 4 oy Arycheogen cine Aaplaces! by abkyl avert gees m the clea mrdlecube > Grmines Qee clase into Hucee ieee aterm of Qurewnowa. ig Aeplaced ley one aueg!(®) 9 assy GL) group then itis CAMok a4 spoulrmaney o& 1° amine - NH ts RN Paerwrares abepharte amine NH) at Dank ses qeomabe amine 2>Seun ot D°amine—? +0 fon actems Gms Or One odem in Qmine is A-eplaced One (QR) ot dD ge hem a Ae amine |¢ os < a coy Ak RONH iR N S cal dec 4 arming ve kcte ROMER on pron detny are| @ Teet: O& Vamine— UShen one hr aa Aeoive it Aepliced by ene aU (R) of axyt (AL) @roup tren ed. tert ony St B’ammine ic ! +k Ron R” aI od =N-R RoNHER H i Sevondarcy aratne men amine oratmmine. @bshen atthe adtkuyt/ ups atta Cotth the nitreen atbern Quee re cect tae oe ae Called as tmple OL Aymmebeical Ldtule Umayrormebeical Ot mixed Awines Aroure Ltterent otal / Poups, @)Struchure Y Ayntnes—> ©) The ni Cmte OF Qrniwer Uke Qromeonia, Pe du volo Casecre< a Love pai elect ten. Oniivegen oebitals tin amines cee ther e Apt lapbseidteed And Hho Abope Qrnines ts + taal. Each | the three 4 icliveof oebitals 4 nidvegen overlap cotth he oreboital7 of Ayduogen Oe catcher clepondieg wepen the Composition the amined. @The ~fousth Ap? apie tdi secf oebrtal of Nitragen fn QU the oe ee a Lene “pau eledtens: &) Que tothe -precence of Aene—patr 4 elettiens. Jere par bene} spar lation OCCurs anal the amined Cs dol alape andthe berol ua lerathan 109-5. ip camie> Bad angle 108? tan ety arntine- Vo uO He fa He 0) Dun Tittmetiyl amine i)©) Nomenclachure —> abn corermnen aston, ALiphaHe Qmwined Qe mOMmed aL W amined WLUPAC Nomenclature O41 Privoiey aumine —>" alkamarmnines” D Cy-N —pMeshanamine BD chy cyeni4—7 Ethanamine Dyce dd, Ny, 9 frapan= harming 2) cty-en— nv, —9 Propana2- amine 3) Ch cfc chy —7 Bulan arrive ty 8) chy Ce chy, —p Backer “harming 4) oe cH-Nw —?. gerrmetiusl propam. leanne 8) op nn %) cco 42, aedmestyl propa bovine g-en-Larmme 16) cH = Cat Ch, -nK, —9 Prope 2en ONS 1) HNC NH, —p Bethan 1.2: cerning —> Hexam-!, 6- amine 12) H—(CH)e NH (© UAC Nomenclature of 4e condone. aunine —j Neabeybableamarsine v » Cy -NH- ch, —> Noernestuyl nmetnamavmne - @®9) Che CH NW-Uy —9_ Nemediysl eddanarmine 3) cy CH NH-cH cry 9 Neel ettranaaming Dabcl-cknincy—> nmethylprepan amine 3) ty iy em “prepa -2- ermine. NW-CH, eS) TPAC Nomenclacthwere of Tenney Arnlnes 7 @el When RR’ and RR” ane pice’ [R-N-R” N,N -cb OUcanemine K Le > Nn nadumetiyylrethomesnine, 3) _ N,nl-cimmestayft eAtramevenine 9 ob he | CHC, —? _nn-cbotigl propam.bemmine. CH, 43% oe Ni nrelrmettyl budamcbemine \ A) Cup He Hoe du, L -|-auin 8) cl digety thn Gis 7 pi Nediedygl bucdem-t ening bits Alaa D® bWyhen RDR! and RPR" and Rl +R” olicamarnine N-abicyl-N 5 CH hy Cn CH, ni-eth J -newredtugl propan- banning Le Aa Dl GO __s yuothyl n-mettyl retin: ZSee upg NC ®WTPAC Nomenclature Of Muornadtec Dene 5 (our — Amine ot, Berceneamine yey Ne amiline 2) co = mm CH, 9 (yt 7 natametiyfontne nH 4) ‘er Q- aniline Of _O-7™ aniline 5) coe 4-bremoanline 0 pebromoamniline 4 eet S pep 4 Nels 7 © Reduction Es Nite Compoundsa—> @)Niho com ounds are Aeduced| +o amines by pase ¢ { Cividad nickel, a0, bn the in Qadle wedi. @Nitvoolkanes Cam also beable Aeduced -bo the Covreapors AUcamarmniyes: Ona Nitrobenzene Aniline ND co Se HO) et eo Fe+htep Nityoeenzene Pmriline .® Reduction woily ren A “preferred becatree Fach te acief cles and hLOete Aciof ie ca pellicle ss the LeacHon. tem, ain ace te &) Tu, ony a Arenal Aegpired| 49 mittole the Aeacten. cry-erieno, Cienas ®t Swivel Ob Pe tHe aay y Nitoetnime Ethamamine (© Arrmonolysic aby) glides —9 @matkyl ot bers Adlude en seeaction voit am ethanolic Aguition of Ornmnenia umdugocs mucteoplulic Aubsbtiton Aeaction jin Uhvch the holoson actor is Acplacec! byam 6) Mus -prrocens cleavage cies C-x benef by armen nmdlecule i¢ Korn at duinmenodycis. ©) The Acacton ic casieied one tna Acaled tube at 343K. @ The pt armme Haus obtuned behavet at a mucleophile and cam “forthe Aeack with any halide to feom decondatey and tech gprs dena Qiernaniwn Aale” @ The oder 4 Reactivity habdes with amines ie ae followt —9 [BED Ber > Reed | i, fe RTH xe eubstichitiel ammaonivm salt “Glide she aumnan|lum 2 CaN be obtained fen base, Prmonta (xucteoprile) &)The “yee arn Cork by tacatiment with a « aft, S NaOH? Roping HE0 + NRO L Of prima Qurine - ©© Arno le Ags the cLisaduen a4 pretaa a mixture ~pacren , Kecondlaity anol tert Qknet and was 0. ye a mnnorden aie, @ © However aprbmoy amine te obtained ara oma for ~peoelucts by tale tage ex Cera of Qrmonia. REX + NH, ———> RSH, + HX ences Parnine (mapa product) er Re eX 4 NH, ee Q-NH, = Remark, exten * Barsine Zaring. HX [tax pa 0 6 RX RNR \ a C -n—R] % rer|® d ; aaraine areemarniuan cast — Gonna Ant Pietra alka ammonium dale @) Reduction ay nvtriles—> @Nitviles en Aeducton woth Uthiwm aluminium | kydserbe La Mind) o cotta te dhageraton —fucodus ce jy Qn ned: “4 OTe Leacton te waool tthe ascont YU amine Kees le: tthe Qn inek nef Cre carhen aon mote thanthe & of grmine. = WIN) OL Naha VG t60H ov MRT LO een A OD Rect nt, AuUCcane nitrle 420k fr ane _ HYni 0 NA(HG)/2450H ¢ CHy-C=N OL SAM 4 +H, 0. CHyCH, Net Ethanenttrile. tapering ~ ee ¢Q. Tdenk hy &© and Mim the xatloul ce. Aencton and Ove thelr ale tae aa el. crear No HY 3 ® Are CYC Br + CON 2 CHCHLON tb K Bor x ei erat —proparenitle | WIN CH CHS NI prepare ermine : @ Reduction y amades—> © The Qud Quwidur en Aecduction cotth Lithium ALiminiwan Auydberde (Li hla) pete Quinec( Lammes) Re-NK, DSP 0 yay oO 2) 1,0 CSN q Acid Qmide Lou fran ure 9 DAA tr : CH- EN, > Do CONN Cthamamide Bthamamine (2am ire). ©) Gateuel, pathaltwide Ayntneate—9 @QOp is word -foe the : ne saa prceparaction 4 ee alin hate © Pritrolmdren Treatment cot ethanolic tarde rydnoxtde spent Poteodurn colt % Phthalienide which on Areating worth aLKyl Aalrde se. hy alkaline Taolga “produces the Ceaieitae «| nppciomay oneC2) Atromadte armnines med Camnot “prepa reeol ometnod, oan Arabde ho ae ye plulle Aubatititton Lot the anion Cae oe b il oF A _P R05 = it C8 =o AOL 3e Cle PhHyolic Actof hthalle do. a intl -4o [Ke oO = eel &-&) to cote He ape a fotaeuium oe N-abieybehthalienide “phthalimide [ nao ep & ef tLoNa + RN, —Pno® ° i $° aLiphadic amine. Socwm sade phthale aud. @ a ined potica the , ae ChACH, Bar Ca aes? Product) + Product 2 Ib ° t_Pn Pra Crh NH, (@thamamire) , “© i oo ) CA, Pu? _NaOH 64) conn ps = ) AecoPrae + CLOLN Reedy) robe) DiAjmann Bremanide Sepia claton Acacttion —> Oot ic QO Mnestycol erras armnmes im UU an oe te Ureatid ie ies tea aguedks ot ethanblic Aolittion of Aadium seid Monte oe Aeg ction, on ete a Oo fe -Feuees iceeae areas Carb ee anit coll @ The @mine 19 Cortes one catebon ers Picea nate ~preaene In the amide. Re & Ni, +254+4NA0H —9 RONH, + NA, CDy+ 2Naby 4040 Acid amide PoumIine Q Che ni. $B, +ANOH — CHP + NOC +2-NABY 424,0 bthamamide Methanamine Cpeerera) dtl! oli hoche Quake) for Rn + Be, + 4 Nad —s CS? ENaC, + 2 Nar Reneanide L = on Aniline 01 Rereeneamne Petronas deormaHe arone) ©OPhysical Properetras—> DN The Lower al c am\nes ane ee catth 4% aS ae v a 2) Prcirroity Qininet LOA Three 04 mote Carben lems axe Liquid and AH) eres ate solid. 3 Aniline and other arm\nes Vee LD Coloutlers but get Colored on a19eage dusto adworphercte oxidation. # Lowe aliphale amines ore Aoluble in water recauuse thes can drdeogen bends vorth watir moleuLes. g) However, tbility deveeaass with inecezae In molarrmart amined due to veers In Aize Othe Hecate QUKyl port High amines Ote esdent insoluble pn wali: A) Amines Ate ALLLLE in Oger: Adlvente Uke alcohol, ether amd benzene. Q) Aligholt wee mre waetler Koluble than aninet. BReason > Dueto Apher. elecbeonesadvi ° than mV , aleguols ieee i ee Quo chrorget intermolecular hydeeagem bonds than Qunined- ®: exarmple > Rutan-[-ol is mote adluble hy water than budean—l-amine - oT and secon Qmines Qee engaged in intermolealac aaroci lon dug to bonding ‘between mitrage ene avo Agee mere S Thee intetmroke aeaociaton ie mete by —pedon Qnes Ham Inthe seton aenines AL there axe tax at ahoms Qnoslable {pe oe bend PoinDY Tectia Qinines clo nettawre intermoleadar @2r.ociotion due to tive Abtonae dbvosem ctém onailable Fike, ae v ape . 2 eretote Hre oder Laila pointe 8f icometa amines ber fpnar> [Firat 9 Seng 9 Tex --4 = & H oe ate Seem Ee eEEEeT an ) | aoe 2 aR Eager Untumole ar dydeoreinbondiing fn sprcionaseyy arnines ’ 13) Compareicom 4 Boilvg port Qrevtnet, a4 and QUeones Of Alrnilad moleetat mass, | gato [ Compound Mola, Man BP/ Ik 7 | PL meg | 73 350.8 2 (GHS\NH | 43 3293 | 5 Gs NCD 73 a5 | A Colts cH, | A. | sone | | 5 wCaugOH | 390-3 eo Z|pChonucol Properetres —p Ohyrence in cledriome roth bostuseen mi bl lay eee atoms amel the -preatnce % Umshwece! patr elscttens over the nrtrqgen dbom wakes amines LeacHve. ©) Me era gen atoms attached tonitro ater Oleo devides the Cowrte of AeacHon Saeed Queto tux Aenzen, Indey , Ae Ory oe ditfee yn pee pea ak ane 4,& Batic Novhere oY Amines — Drrmines, bees baiaie in nature. A7eackt corth acids+to AotdE: RAH, thx == Ry xO VaUphadie amine host : Breer ne + HY — 2 AnmiUne. Anilnivm cleride @®enine Lotta on cheeatimenk witha baae Ul: ex oth tre. parent amine. 5 6 r gentry +0 ——> RN +o + x© Rokk aveenk aumnine @®hrnine Acuts axe AOLuble vote bout Insoluble inthe ie Aolverntz Like ether - ® Aeaction tethe baate of the aapayacion 4 amines “yoo the mer baate organic Curmpotemala ingoluble in wood @QThe Acackon Y% amines orth minal Quola to Qyemaniumn Lott ALWou rat “Hear Que b@ale by nature. @Amrrnes have 0 Lowe -babe of elecreone en nitro: atem dun 6 USstuch Hrey bohave as Lewit baae. Oe sees ie Loaster +0 ave —prrotonsitad amine ; ; ° GH, +40 = RS -+ 0H & k= CeRealler) (ene) (0) “ Dyg] = Contant K(40) = Ce Sn ICR] Cen) ( e NaOH, ykb = [x Sy) [oR] (RN) KC] = b= Dissociation omutant o base © Baaie achrom gte Of amines ht exprerad ty tewme % Kb and pKb pice = leq Jeb Basic ater KH hb K re Ou the value Kb & Amatlet the value Re, crore tethe hue Yaed Vice verte. % p ®& pkbvalue % ammonia ig 495 wshile He peo volute aiphabe Qwwines Aanie sto #20. D ble dan Loot ALanring +2 electtan Lortebeausi Abwoooing ~L effet Gorey as rong & ae ® Reaider induotive there wee Other ay Uke Aowotion : fo Aindearac, eto, tri the bante Atrem, Qrnines- @Pasic mature ao aumine dopencls pon the eae oe the jon accentng & -poten the acd. * “4 ? q me @rterce the mote Ateble tre Catton te Aglatveto the Gmine, mate batie iethe Amine: @® Mkamanmnes alicholic amines ate ror’ baste thon ammonla—y @®Quo-tothe eledeen Aclaaimg mative altel a vale oe earth Korum Rely pushes election veogen mmraces the lere—paty of eleatters mdte anclable pee @®Ahoedng Udihh the. ~feolon of the acid. &) Moreover, Ihe Aub Sid ammonium fen doemecf rom “Who Amine jeu aAtoliused dus+o cls persal op Ihe ? wiHyve change. 4y the +L efyedl athe abet up: PyHenee , UU lamnines 0% ALbtamamines Mee ahrongee baees-tham airnmonia, 4 WW 1D Q ne + 4 O — Qn y Auiphalie Proton Pseotonctizd amine Qimine Cubsbtrded Qarvmenwiun jen. H \ none he =—— ny x paste i} Quremnawia armani fen. ® Pace Strom 4 1? Pond amines In 4anvous piace pace @ Bane trem gts ae canted nto daprnrols wpern “Hire +1 Cpeartive bncluctive ot) og He adie pup attrohas Ustth tha miteren ater tthe Corresponds anines. OE) Thus peater the mumbet Of OH inthe Quntnet ,rmrorce voll he the baste Atrengte athe Qunines. Hence, Hre Cedor Y baaich amined Inte, 4aoeous es Rs as -ollows— § Y 4 [ery ahaa’) Seay > Priva > Ammonia | 7.) ® Basic strength 1 Of, Vand 2 arnines in Aguecistthasa7 @ Baate Shremeh amines inthe aqueous “piace clepords upen the -Hwree ie Imolurctive ofpect: ¥ alkyl pope e\vosion (Hydeastiory effect And Artesia tivdbeana.. ®Munthe agqpeous phase, the auwoatibe ton coastons get Abplalised nob ee ae ef feats af the oLKyl Group Letteck) uct ale by “usiylon torth wate moleutes. The froder the Alize % the lon, Aerace coil) bo the Solvation anal the Jess Atabilced Lethe jen. @®The -peohoratticd “pe arnine eof inthe Agnecut phase is dg Q custo the on 4 Aree intevnnoleuda Hyclog bends uo Hh watz. Red FHS <== RN + 0 laine _pesterattae Loumine lamsice | Lournine Mie e=s=— a R- \e H a Ge cs H- --- --a ibed by Trtewmolenlar Hbordling ® Whe protonated Ae Quenine inthe Agpeoud phase 4 eee dae torte on tren x tux pvtermolecntar duydecgen pene vont nscttor Ht Protomedad Laumine Atos Wine +48 == RR, + oH aamine -protenctiad Dornlne x A qa tat ----- Ly Hie eos. > wt Go = Gay Protenatiad 2° armnine Lrobilicecl by Intermoleertas © ota tesxcttaky amine eof inthe we | ~ph9.ne tetern Ateble diretotre ation ene ©Wntewwoleatar Cn end uotth wot: RNR +O =H R LP +o? Baraine t nil Larne pad pect (Ly Aiesevaat cial A clag alba i salle beptoratzel Zamine q & 1! Len Sree pee aes o he yA fe y ie ya) BeNEH egy Ronny D Raney OSy ! arnned| Becxeaanng oreder Y extent Of Ayden genbor ding ba ode Grd oedah of tabily o iene i, tolvadion (Rycteoter) @® Crreakie ic “the arab of Hoe bb bated? Quanto cation. Atrerget aloud be the comresperchig Qumine Qs a beso. ® Thus the oe bosioty of abiphaitte arnine Aloud be oppeaite tothe brcuctive ty based oredr. @tlena.tte cedar op basicity 1s [pet Gumine -Seesn pamine 7 TeeHary amine ro ey ayorre| @ecerdly, when the ott te Avra, bike -Ch, “there ig WO atesse Ainde@nee. bo dovogen b ordi ' @rinjhe anne group te bigger tran — Cty 7 there call bo stewie £4) ce. +o bonding. @Hence, Comadwelng alte Ae amlne ig The mmoct basic Mthe us ALLEN. © jxOrheretste, the greclir of lanaic (ncaa gm Aweat Gud am ines ound ext Hdoh amines be agpeout KolLLHen ig QA foULo bs —> CHNH > CHNH > (CHIN > NH, @ G) @y Pammonia. @”) @") ae Quomonia BH AeyLamnines oe Aniline is Leas basic than ammonia> Dgnamivne O*%_OtheL ee qicup Is attached obrectty +0 the zene Lelng. St Acaults Incthe Wnalweac! elecbisn pase ennit aterm +0 be in Cont ation uottythe Gane cnd and Hus ammokiug tt less available meohenastion - Hocis cloae the AeLonanes Sheuctsres anilne, Hock awiUre tt a. Astenomet Mbit! athe pre : Oe onamnce Atyu . “ camanical O% get oe Ba. Nh Cit has cS oo cy AD Oo —— ‘s 7 Resonance camenical Abracteres f Aniline ®) On the other hand, arulinium ion Obtalnect by aecepeg cain oe oC ALLO th Abe ctheres er kekule aburctirres: My Ny . 7 Le Rererance Abercteres (kekulee Actruchsree) | aMWe Knovo hat Grealir the number. 6) Renee Atiuctivres, » Greater lethe Sbabibty, theresote, Bake bows we Can injer tha aniline ating: Love fey arc, btuictires je mrdee stable Han omilirtivin ion hava ently hwo Lessromnce Abuuclires d Hence , the -foolen acceplability vethe bawe nibire Saati ee othet weg netie Treinen wood be Sarz that Y Qarnmonia- In cae Y Aubab tle aniline, tte obtetvect Hooke the electron Aca ups Ake OCH, -CH, pnocease haaia atrength ushecear clecbten coithdeanoivg Groups oe -NO,, ,~SRH COOH x decvesaas the baste theang. Maange the pee’ WWthe deeceaking Hedy et ine » pauhcieng ®OGusN, ale Gisnt OL4s, sy ON tne Tre decveessing Geir Of the baste Aveeneln fea “pollen & HSH GHSNih 7 NH? Calis Ni “sede eaten een oder tt basic a °@°S.® -™ Ana The, mee as hee ye ig Q4 ean -ard Ts, @®@)Adkylasion —y OArmines umdega alkylition en Aeacton Wsith atieyl halides =) Acylation—7 Muproobe and ascomaltte and Leusn : Se acid cies ae and eators byibe mucleophilic AnbalaEn Leaction. @Tus Aeaction te lenown as aolodtion @Intws Aeaction, the Aeplacement % oe octem of NHL Be DNH group bay the a Pop amd the groups cblaned by acylation Aeaction axe Known as amides. © Whe Acaction is Caserted ouck inthe —preaenae QO kaae shan the amine Uke ~pyicive , Ulich Aemoves Hoy 20 ed And abipathe eqpulibrivm tothe segte Aomd Aide: : Hy Ethamarnine Shamoylenlocide, \ “ Oo Qtgnn-P-CHy HEY gta eats Cts Gs + CH-dht Cts bh +HCl x ZOox N- ethamamine a Gs picananide. ae 9 B Bane i d a BCH ee Onan eee (eg NH- CHa + OH, COOH bthanoie aunugeide N=phenybetramanide Berceneamine (Acetanilida,) cr Aniline @ Amines aloo Aeadt uth borneol Chisercde GetsCoet) and tus Reaction ie Known Qs benzo ton. &B CHyeNHL 1 oe = CH NH Fe Cels + He Medhamamine Bereoylblereide Nermetubbenzam ide Othe seacton 4 amines Lo tth Cereb lic acids yells Aalkts, at oor “lempecatinres- ® Gaxbylamine Aegchon 01 Teccyanidetect—> v @Auplabe Qud aromatic — pion Qmknes on heat with chlecotsem and ethandlic pores dtoxida per lege jena oe Carbylamines hich Gre purged er foul Amelling aubutrnce. B secondary dea Teorebarey aratres cho not aluova Hue AeacHon. “¢ OTe Leachon te kmoum as Cadalannime Aegon itocugwidectert and i urd ar a Teak yore aoe | Amines i. hea Ron, + CHL F SKOH ——> RNSC ¢3IeU+3BHO Parle auteyl ico amis heat. CHC NH, + CHCh + 3KOH ————S CH,CUNC + 3 IeC{ F3H,0 Ethanamine _ Efrupl ieocyaride, rey ab plore aumine) — . Aubstancd) NH NC leat > 4 Hel, + 3KoH ES - +3) +30 AniUne(Renzencarine Ph teoawyanide Greats Bsusmahc amine) Gee ccm | ous© Reaction with nitrous act NO} @© Atithe Hucee amines Aeaat oA worth mitroud aciol Coton Le prebareec} fnaitu a amineral aciol and Aodiirg Mitrite- we © Pern oluphatic amines Aeact corth miproud auio/ to olivhatic catomiurs 4alts vSlich being unsizble, beets nitro aca ard aliohol.. © Quantitative evolittton of wit fe eee nthe ettimadton Aaminvarids Anof Ind. QNH + HNO, maa reais, fe-nOu®) _ eo Rott PHY Lf abiphodic arming alighottc —-_Aleeholt. aesnium £ALE (umatable’ © Meomabe aed Qurnwed I onthe om\proud aval oc Low tempercatuves (ak 242-298 Ke) to Nae Macon dalta- OThas Aeaction te called a Darvotizaten deacon, ® hrocotz2aton LOK Gre Lard ie Axpretneale a the voserely of the Qeorncle Compouncl he @532-2981¢) Np ue 3 PONCE Ch eg oo +N4U +20 Amiling ao hazonivm (itetiguaiteonaln eirg) chloe @Se and Ae ares react orth the miProus Ato Ira ciftevents ramet. > p©) Reaction votth Cuegt Aulphmyl chloreide o Benzene Aulpheryl eblecide —> 2 @ Benzene Aulphenyl cdloride Ces Sac}, uch ig aloo Kno as Hinaleorge 1 on , Leads corth -piel and Aeosn amined to ms hen amides. md (A) The Aedeton benzene Autphonyl chloride vith the wemosey QA tiNe yreldu Neetyl benzene dulphen anda. The ay gen attnohed toniheagem In Aulpharoumde fe Abul quale duets the preaence 2 At eleaten voithdxauoing audpheryl Groupettence [eed in alkalt. \ CO-EET Bur ats D> fnrals tha oO i iO Unslesng Y Eeamonens. Hredlgt bencenss onan amune) é “Th in oueale Ointre Aeacken Lorth detsry amine , Ny ne elect bomzene aubphonansole tc eq. Since, NN- boneene Atlprenamide dees ror Contoun cbuogen aber oneal tonitrogen atem, iit wot adde and henee InrOluble in QLK oi ° 9 Vi a i O-PS hse > Or fprpats te 7 falls, Os Honaeigt — nretiybetemamine ni nroliettyllaancene aa (Lamine) Aulprengmde fr olka l®’) OTechog amumet clo wat Aeact vith benzene Aulphony chLertele. CMG 7 Cri 4 th-Gltg. ———2 No Reactton wht, Ms Warsong glamine (NN-deetayl-etranamine) ®(ws ~prropecty 4 damines Aeachrg vorth Loncene— Aulprenyt Abode Ina hy wmrammet le wood 40t Ihe cUetincton —pemg, And cperets amines Ond e240 He on oF Om xXhure 4 Ourn\ned, Glectrophile Subsblalan Rescston—>y @sn Queomale Ourines 0% amilthe, the —NH, group ANOUGL ouitve Meomnette cL Ok the Lone-pate electrons en Niteagen otbom Wee In Hae CO ec lemaae voith the bamzene ot © Asa Aca Hu, the eleatren olen hs duh at crete Ond pare poaitions Of the benzene rhe | aniline. OTs, NH, group tk veto and-haseg obtrecting and a powerful Sener Gop ® BrominoHon—7 @ Aniline ends voith bwomine wood ok s000m -bemporabture so Gre, a nsbute precipitate 4 2A, b-trtbrermwoonlre. HO Mo. Br OQ +20, 2 ST uae Aniline 24, 6-tribromoantline (Beate ppt) @The wrain problem obourved diwung electrophilic Aussbliten Acachons queomaltic dmines ie thack Y thelr very dn Acauite duo-to utuch eubalilibon +o occur at betho ahd -harcapoartiond. So, dhe p* venation mre uodadts take} ariline desevdstive , the achvasg ot GL NI, Group awe tobe Csoprolled. &Ws cam be dene peote the —N laHen Lolth aceHo on the deaired aubstitrban eee ee aulpdhtaltd atte 40 the Perea Oo ie the (5 vd, Ae, an Amnilbne ey) “Aceon ( ee onbypbede N- premteiteeneanide Ac Ueda | br, + CHLOOH Ni, © H° oe OH ae 4 fl 2 {= weabrend a0 acetamilide preg bsrerwo alone te ge re) (&) The Lene elections on maven ator of Gcétam de iraerllaats vorts oxygen dueto Acseramee pages ae avoslable donalnen eed doom pases ie epee ae meg by prop fe es ot Arninn Forp &)® Nitrabon Quang the claret nitvacion aniline, in-the acicle whedium ,anibre is rhenattsiel ho edd auniriwm ion Such Ie eo p those is shy, bewides the cH and ~pore derivatives, s'yniflcant aroun oe dae 1c alo i Me Coneni0g, 200k Ne —— > =~ (serene Owe Amilrne vk NO, naz (s) ce) ra >) — le (2%) &) However, poste img tre Na acetylation Aeaction oo, Ped dude tA nreachon Con be Controlled and the pomiteo dese vasive Cam be abiamed a4 the prepa tut wae ° NH COCH, =~ a dine ~ \ 4+ CtrNg = __£ __» ) Lf ee 2 Avaline ate aa Keetanilide Acebe ambyQoe HNO). HSO#, 28816 Gane, Cane Ni NHCOCHy < Ho Gt [ <= il J NO, Or. . peonitwo aundline _Pemitrn acctamilide ®@©sulphenastton—7 : ®Amivne Aeact with Concentrated Autphwele adel-to pen cuniUnium Aydsecogen £ulphale ostrich en beat worth Aulphusele a apmiet oLLLaed prominobenzeme cand, ceo mourn ag tolpramibe acta, at the nent pute : ri Balog ie ASR 478)¢ oO + 1,804 —> aaa Amine _Aroireiuan. OH Hydrogen pola. sulphani Leaded If iy Zuittec len. Oo ®Special Nate: — ny Amie chees mot eee Foeredal- Crate Aeathon QUalaben and a on) due to hae on voit, alusetniven ide Hre Lewie arid istuch Le used as a cakalyat dD) Due totes, weer 4 awilene acquires poative Ong hence a as cleachy ef Cor iis i sttionae Reaction.| Ch aaeaais Ads Atare the gure. 4 schcil RNPAP wheee Ro Atamdatoe aun ouuph qup a ion be UP, BO. Hs07, Bye ole, | ®They we moumed. lay duping Warconiur +0-+he | rane Of Het poveanst qe lon sPoarn Udbich +} bey | Oe ed, EL by dhenrowne P| awionw | Auch 2 Criserde, Au hoogen Aulphati, , Ae: “ © DThe nO group '¢ called as cUaroniurn Group: &) Gee _excournple. >) Cgtsn OP — Benzene Haconiv™ chide S GgN© HB, 7 Benzene diacomurnlysdraginsil idle ®© Posen alichotie avnmnes {ro unatable ow dtaran iw AoSt: Precien cuore, Grn ned curcene Laran|wn Ps pest cue Atabole °c ot eye In Aolition ok Lod Jerperetiliares (73-248 ©: The Arabs ty a Cae davonturn jon ts dis Fo ey : @_ fi: Pm A: powrge S i) =N\! Comontcol Ader ures Mrene iacaniwn SS : —n®M Ss0x0n1 <7 ecm ees Seal ie—prebaread by th, e Hoactien of aniline Witty nitrous acted at 24-24¢k. @Nitrous acted te 4rooduced inthe sanction mixture the Jeeacton of Lodwm nitrite i a aed. 4 ° @ The corveczion of “pam ctomnale auwines irto djowonium Kosta (% Known WL darcttadion. ® Bue to vee bruchblliy te duazonivm alt is not Gonenally Atel and te aed ierorvael ater atic " ‘ 245° 248K £0 CHEN, + NANO, rH —_—? GHENT UE Nach +2 HO ® Plays a ty BenzenecLincomum cnleeide 1s a. Coloweleas Ouse ald, gels read Adtuile' ty waite anct le-ctable in cole but Jeena Worth voodie Shen Watered. She decomposes easily in ee ly Bencemediaconium te wodlae Inacluble ang Arable at Avoorn temperate : Chem ital Reactions —7 Om a = OIC of duozoniwm Aotta Coun be baconclly divided into 30 collageetes > Reacton brvolvi als plocament nit > Regetiony jnvolviry Atherton OF daw group. Reactions invoking dt a ‘nn > | .&© Siavonium Groep being avery 9-ovo { toa , is sean ar otheke Ml 4 oe ue wy geo ard oh which ceplace Mihyagen iftore the axomatic | el h) Thre it Chay et S tegen Pe ne pes fytorn the “eeaction ¥) Replacement by halide or cyariole fon ® The co Bo ond —Smaleoti ek Cary eaaily ba introduced Inthe bunctene ef Incthe redlnte % CLD ion. Om: Arcachon te Caled fd Sander Aroachen. Accn 4+ Ny Rone nitsle Lrornne Carn Lao be dreading the onde cnaloyen Auemotively On.erine et riroducad, bs“the benzene 40) danontwm Lolt Adluaken ots conreaph acid pn the ~preamnce coppe oe Thx peoacHon Ie as my Aaacton. @ SOB SM CuJHO _y Arcet + Ng 4. COX aaa Cisrolemzent Remeene daar! CufH®r_, Av Br +N + Cux Aalide Bromdbentene ® Special Note:- The yreld tin the Samdmeyortt JapoeHton M “pound do ba kettee Hham the Crocttbernann's Soccer.Gi) Replocwmenct, Lod = Oaodre Te Or tw nee tho the henzene si a he A on {6 worthy potaoaturnn joldha, jiodobegsene ic eee Cc 4 kL ——? [oo + KAUN, ide jen} Repla WW é : te treatadl votty as yuu) owe tele edazaniun becate den ee on maces ditonnpoces to fy tsneide- Po? é + HBFy —? 7 2s yr (wv) Replacement eetoin i agen Angpopeapho- ern aco a tet id) Gt Oe ce oxidised +o phroaphoreous, ac “coe pecs Jey Hef, +40, Av ENG HP Os, He CHEOH 5 Asc H +N, + CHyCHO FHY Ww Lo came = & Se @ arioniumn Aa kolucton sayy ‘ oa the colt gett | Cee | Co + HO ——? Ny + Hef |Mi Replacement ey witnagacups 7 ‘ . When bencene mnt borate f¢ Auatich, worthy, aguveoud Aodlum nidstte AdluHon inthe -predence copper the Uanoniwm rp fe The aro -producz obtamect awe an extemclacl Con} wget Aystem Arawing both the orometic si ioined! Trough -Hhe —N=N- bone). t @ Trea com wnds area. OKfern colowd and cue uasslon dee ie © Bencenedazomivm chlovicle 2atd voith pheno) vm Ustricly “The phenol maolecute act, ts para—position fe coupled volta the cLiaunomiwm sade +o yo i ozokenzene- reamocion 16 CoLladl ak Coupling Axaction, © Ws © Sterns pernedion of aramiuen AOL tah aniline -tyrrstnOOFeO ReneS Mw an excorngle OF electrophilic -nbotiliion Jeoachon. 4 on® : RP Cor os Cpe yonnee +HO RBenceneclioronium Phenol eee chee} i de Gebnge dye) yyOne “ =P Se + Be Ne, ———9 € Sen 0 na, Remzenediazonum Amiline P-Ornirocuvoben rene Chhoetde Yellows die) 2 + HC @repe 60.0 cLanomiwrn Aost bn dyptheaie. (a unrds —> OE is Choe That the duaonivm aaltr are 2 ee trwhverneolatis cthe introdueton EP 6h Oy, aE en Oe Ne Gees [ota te oxormalic Auing: Ory Sh and iodides Canmot be -prepired Lect. Araloguroton athe gprnginnt ct othe muslesphive aubesiiniton Of o-leine Ie Ce loncome buk cyanobencene Com be cantly oblaned| vo | @® Thus, the paplacernent of caro quoup by othe. : In prepares crease AwesH- turaorale. Corpo) prepwred ley direst arbatitilien In benrene Ot