Professional Documents
Culture Documents
By
Altaf Hussain
Roll No. 56712
DEPARTMENT OF ZOOLOGY
HAZARA UNIVERSITY MANSEHRA
2023
PREVALENCE OF DIARRHEA IN SUMMER SEASON
2022 IN DISTRICT KOHISTAN
DEPARTMENT OF ZOOLOGY
HAZARA UNIVERSITY MANSEHRA
2023
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DECLARATION
______________
Altaf Hussain
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DEPARTMENT OF ZOOLOGY
Hazara University Mansehra
Ph. # 0997-414167
CERTIFICATE
This to certify that the thesis entitled “Prevalence of Diarrhea in Summer Season
2022 In District Kohistan” submitted by Altaf Hussain Roll No. 56712 to the Hazara
University Mansehra, Pakistan in partial fulfillment for the award of the degree of
Bachelor of science in Zoology is a bonfire record of research work carried out by
him under my supervision.
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Dedication
I dedicate
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ACKNOWLEDGEMENTS
helped me to Come into this universe. I show special gratitude to the staff of
patients who participated In this study. I would also like to thank nurses in
charge of wards and all nurses for their help during data collection. I would
like to express my deepest appreciation to the following persons for their kind
Altaf Hussain
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TABLE OF CONTENTS
ABSTRACT ............................................................................................................................. x
CHAPTER-1 ............................................................................................................................ 1
INTRODUCTION.................................................................................................................. 1
CHAPTER-2 ............................................................................................................................ 7
CHAPTER-3 .......................................................................................................................... 15
METHODOLOGY ............................................................................................................... 15
CHAPTER 4 ........................................................................................................................... 16
RESULTS ............................................................................................................................... 16
CHAPTER -5 ......................................................................................................................... 21
REFERENCES ....................................................................................................................... 25
vii
LIST OF FIGURES
viii
LIST OF TABLES
ix
ABSTRACT
countries and its prevalence is very high in rural areas like in the valley of
were calculated.
Tables, bar charts and plotted charts were used to present the data.
Results: Total 2057 cases of diarrhea were identified in the six months
duration of the study. The total number of males with the diarrhea disease
were 1226 (59.6 %), whereas, total females with diarrhea were 831(40.3%). In
addition, the total numbers of diarrheal cases less than 5 years were 767, and
Kohistan was much high as compared to other big cities of the country.
x
CHAPTER-1
INTRODUCTION
1.1. Background
Globally diarrhea kills 2,195 children every day—more than AIDS, malaria,
and measles combined. That is like losing nearly 32 school buses full of
children each day! 1 in 9 child deaths are due to diarrhea, making 801, 000
child deaths from diarrhea every year. This makes diarrhea the second
leading cause of death among the under-fives. For children with HIV,
diarrhea is even more deadly; the death rate for these children is 11 times
higher than the rate for children without HIV (CDC, 2012).
insufficient hygiene.
According to the CDC, rotavirus is the leading cause of acute diarrhea and
diarrheal germs are spread from the stool of one person to the mouth of
water, food, or objects which become contaminated with stool in many ways
including people and animals defecate in or near water sources that people
1
wash their hands before cooking, people with contaminated hands touch
objects, such as doorknobs, tools, or cooking utensils etc. Strides made over
the last 20 years have shown that, in addition to rotavirus vaccination and
hygiene and sanitation is not only possible, but cost eff ective: every $1
and then least in high-income countries (HICs). Even though the variation is
not that substantial, the case fatality ratios are. The top killers among the
In the year 2010, there were about 1.73 billion cases of diarrheal disease and
7.6 million deaths in the underfives in 2010, 64% (4.879 million) could be
attributed to infections and 10.5% were due to by diarrhea (Liu et al., 2012).
where half of the deaths are from diarrhea. Among all children under-fives,
2
The average child in developing countries experiences three or more episodes
Diarrhea is a disease in which the patient has three or more than three loose
countries.
worldwide and 99% cases occur in developing countries, 69% victims are
would mostly occur in hot areas. However, a lot of patients were observed
popular spot for tourists. In addition, as per the local residents the food and
water here are considered pure and free from any of contamination. Diarrhea
income countries and is very fatal in the young age and may cause death if
3
Although, how fatal disease diarrhea is, but unfortunately, there is no data
season. This study was planned to find out the prevalence of diarrhea in
Diarrhea is the fifth cause of death among the under-fives causing more death
50% of these childhood deaths occur in sub-Saharan Africa and despite the
Nations, 2015). In Kiryandongo, many deaths among under the age of five
years are caused by diarrhea and its complications (Bbaale, 2011). For this
4
Kohistan.
Pattan Kohistan.
been a shift in the diarrheal causes among the under-fives attending DHQ
3. What are the various factors that predispose to diarrhea disease in patients
5
4. What is the case-fatality rate of diarrhea in patients attending DHQ
The aim of the study was to ―estimate the prevalence of diarrhea cases in the
valley of Kohistan in summer season 2022.
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CHAPTER-2
LITERATURE REVIEW
2.0. Introduction
diarrheal disease among the patients, the factors that predispose these
for 1 in 9 child deaths worldwide, making diarrhea the second leading cause
of death among children under the age of 5. For children with HIV, diarrhea
is even more common and deadlier; the death rate for these children is 11
times higher than the rate for children without HIV. About 2195 children die
daily of diarrhea each day. It is estimated that about 801,000 children die from
Each year, an estimated 2.5 billion cases of diarrhea occur among children
under five years of age, and estimates suggest that overall incidence has
remained relatively stable over the past two decades. More than half of these
cases are in Africa and South Asia, where bouts of diarrhea are more likely to
result in death or other severe outcomes. Mortality from diarrhea has declined
over the past two decades from an estimated 5 million deaths among children
7
declines, diarrhea remains the second most common cause of death among
children under five globally, following closely behind pneumonia, the leading
estimated 40 per cent of all child deaths around the world each year. Nearly
one in five child deaths is due to diarrhea, a loss of about 1.5 million lives
each year. The toll is greater than that caused by AIDS, malaria and measles
account for 29% of all deaths of children less than 5 years of age and result in
the loss of 2 million young lives each year (UNICEF, 2013). Proportions
of health morbidities in 2015 it was shown that acute diarrheal infections were
number four with a prevalence of 18.33%. this was next to protein energy
among children under five years of age was 22.5% (95% CI: 20.3 - 24.6)
the prevalence of diarrhea in children below the age of five years as reported
by heads of households was 6.1% and most affected were children in age
8
0.001) (Mashoto, Malebo, Msisiri, & Peter, 2014). In Kanyanda, Luweero
Fives
So many risk factors are associated with diarrheal disease among the under-
fives. The causative organisms can gain access through so many pathways.
Among factors that have been cited the major ones include environmental
attributable fractions are in sub-Saharan Africa, south Asia, and Andean Latin
children with vitamin A deficiency, the risk of dying from diarrhea, measles,
9
In a study carried out in Kabul, Afghanistan it was found that the highest risk
of diarrheal illnesses was during the summer months (incidence 5.71 episodes
per child-year (95%CI 5.48– 5.96) and lowest during winter months (2.12
episodes per child year (95%CI 2.02–2.21). The seasonal trends in hazards are
illustrated in Fig. 2. The risk of diarrhea was 63% lower in winter as compared
to summer (HR = 0.37, 95%CI 0.35–0.39, p<0.001). Among children less than
six months of age the incidence of diarrheal episodes was 2.35 per child-year
(95%CI 2.15–2.57). For children aged six months to less than one year, the
In univariate analysis, the risk of diarrheal illness was 60% greater among
children aged six months to one year in comparison to those less than six
months of age. For children greater than one year of age, the incidence of
diarrheal illness was 3.48 episodes per child-year (95%CI 3.36–3.60) with a
48% greater risk of recurrent episodes. Malnourished children and those from
who were born to mothers with greater than primary education had a lower
education or less.
Among children from homes using wells the risk of diarrheal illnesses was
significant difference was found when treatment with boiling was reported.
Food storage with refrigeration, having an in-home well, use of a toilet with
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septic/canalization and maternal hand washing with soap post- toilet use
diarrheal illnesses at 15% and 20% respectively (aHR = 1.15, 95%CI 1.03–1.29,
education, maternal hand washing with soap post-toilet, and use of a toilet
illnesses. Maternal education post primary school was associated with 21%
lower risk (aHR = 0.79, 95%CI 0.69–0.91, p = 0.001), and hand washing with
had a 24% lower risk of diarrheal illnesses (aHR = 0.76, 95%CI 0.63–0.93, p =
0.006). A trend of reduced risk was found among households using an open
well versus a piped water source (aHR = 0.87, 95%CI 0.76–1.00, p = 0.053). No
sleeping with other children and number of rooms in the home were not
it was noted that the occurrence of diarrheal disease was associated with the
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diarrhea was 4.3 times more likely to be higher among households with two
children compared with households with only one child [AOR = 4.3, 95% 9 CI
= (2.9, 6.3)]. Similarly, the likelihood of diarrhea occurrence was also 22.4
households who had one child [AOR = 22.4, 95% CI = (7.8, 64.5)]. Children
aged between 6.0 and 11.0 months had 4.8 times more chance to have diarrhea
than children aged under 6 months [AOR = 4.8, 95% CI = (2.1, 10.8)].
between 12.0–23.0 and 24.0–35.0 months was 6.0 and 2.5 times more likely to
be higher compared with children aged under 6 months [AOR = 6.0, 95% CI =
of diarrhea occurrence was 2.5 times higher among children whose mothers
had no formal education compared with their counterparts [AOR = 2.5, 95%
whose families had medium income [AOR = 1.6, 95% CI = (1.0, 2.2)] (Woldu,
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2.3. Case-Fatality Rate Of Diartrhoea among Under-Fives
Diarrhea kills 2,195 children every day—more than AIDS, malaria, and
children under the age of 5. For children with HIV, diarrhea is even more
deadly; the death rate for these children is 11 times higher than the rate for
diarrhea causes more than 450,000 deaths annually in children below five
India, 22% of all rotavirus deaths that occurred globally. Four countries
approximately half (49%) of all estimated rotavirus deaths in 2013 (Tate et al.,
2016).
health benefits that could result in countries that adopt rotavirus vaccination
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reports came from Botswana where following introduction of RV1 into the
(Enane et al., 2016). In Uganda, a majority of the under-five deaths are due to
14
CHAPTER-3
METHODOLOGY
hospital of Pattan Kohistan. The data was collected using the hospital records
of patients from 1st March 2022 to 31th August 2022. The duration of six
months was taken because the weather in these months is a little warmer and
season because the residents as well as many tourists visit the valley. The
Microsoft excel 2013 was used to analyze the data. The two variables taken
diarrhea. The age wise distribution was taken as having diarrhea for less than
five years and more than five years. The statistics of frequency of distribution
of diarrhea in age wise as well gender wise were obtained. Moreover, the
tables, bar charts and plotted charts are used to represent the data.
15
CHAPTER 4
RESULTS
The total admissions in the six months duration from March 01 to July 31,
2022 were 21,523. These admissions included the daily OPD patients and
emergency patients. The diarrheal cases among these admissions were 2,057
as shown in the Table 1. The month wise prevalence of diarrheal cases was 67
in March, 153 in April, 316 in May, 562 in June, 564 in July and 395 in August
respectively. The bar graph in figure-2 shows the month wise prevalence of
diarrhea was 1,226 male patients and 831 female patients. In addition, the age
wise prevalence of diarrheal cases was 767 less than 5 years patients and
1,290 more than five years patients. The peak incident of diarrhea was in the
months of June and July, which were 562 and 564 respectively, as illustrated
Figure 2. The month wise total cases of diarrhea less than five years were 26,
63, 119, 246, and 204, 109 respectively. Whereas, the month wise cases of
diarrhea more than five years were 41, 90, 197, 316, 360 and 286 respectively
in the months of March, April, May, June, July and August were 35, 97, 177,
341, 326, and 250 respectively. Among the female patients, the prevalence in
these months was 32, 56, 139, 221, 238 and 145 respectively as shown in Figure
16
3. By looking to the percentage of diarrhea in different months of summer, it
becomes clear from Table 2 that it was increased in the months of June and
Grand
21523 2057 1226 831 767 1290 19466
Total
17
Figure 1: The peak incident of dirrhea
% of males % of females
Diarrhoea with >5 years cases %
Month with <5 years %
% % Other
Diarrhoea Diarrhoea
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Figure 2: The Age Wise Prevalence of diarrhea in Separated Months is Delineated
19
Figure 4: The Ratio of diarrhea was Increased in Hot Weathers
20
CHAPTER -5
different regions of Pakistan. Beside this, it is more common in urban and sub
118,000 lives each year, most of which are children <5 years living in rural
The findings of this study also showed that the proportion of diarrhea was
high enough in the region. There were total of 2,057 cases of diarrhea among
21,523 admitted patients. The percentage of diarrhea was round about 10%
large as other big cities of Pakistan. The findings of a study across Pakistan
showed that in a duration of two years, the total numbers of patients with
acute watery diarrhea from April 2019 to May 2021 were: 23,212 in LCH
study, the results of our study are alarmingly high, because this data was
The total males with the diarrhea disease were 1226 (59.6 %), and the total
females with the diarrhea disease were 831(40.3%) as shown in Table 1. This
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significant difference may be due to the consumption of street food by males
in hotels and bazars. This particular is in line with the findings of a study in
diarrhea males (10.4%) were more prone to diarrhea than that of females
(8.1%) .
The same finding is also confirmed by another study, that rotavirus is the
single most common cause of acute watery diarrhea worldwide and studies
have shown that rotavirus affect male gender more than female. In addition,
the weather has also great impact on the health of the population. It was also
found out that the ratio of diarrhea was increased in hot weathers (Figure 4).
The weather in August and after words becomes colder in the valley, so the
hot weather is due to a number of reasons. In hot and humid weather, the
growth of pathogenic organisms in the food and other material get increased,
also summer is the breeding season for flies that act as mechanical vectors
also adds to the outbreak of the infectious diseases. The drinking water
corrosion and long track, agricultural activities, lack of personal and food
hygiene, the lack of regular and continuous chlorination and lack of water
22
treatment facilities . Our study’s findings are in corroboration with the above
mentioned study as Kohistan valley is also a rural area where most of the
drinking water resources such as water tanks and springs are contaminated
by above mentioned impurities when there is heavy rain fall. Through rain
water these contaminants get mixed with the drinking water, which
water and the situation is far worse in rural areas 90% of the population is
deprived of safe drinking water [10]. This clearly indicates that drinking ater
The main limitation of the study is that data was collected from one hospital
only. Although, this civil hospital is the biggest in the region, still majority of
the people visits other centers as well. So, if the data was collected from all
5.2 Conclusion
diseases like diarrhea is not confined to hot and populated regions only. The
study results clearly showed that the prevalence of diarrhea is much high in
the region as compared to the other big cities of the country. There were total
2,057 cases of diarrhea cases identified in only one hospital of the region
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5.3 Recommendations
drinking water has to be made sure for people of the region. For this purpose,
be carried out on larger scales to identify the burden of different w ater borne
diseases
24
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