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INTRODUCTION TO NUTRITION
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Nutrition is a vital component to overall wellness and health. Diet affects energy, well
being and many disease states. There is a connection between lifetime nutritional habits and
the risks of many chronic diseases such as cardio vascular diseases, diabetes, cancer. A well
balanced diet can prevent such conditions and improve energy levels and over all health and
wellness. The basis of nutrition is FOOD
Definition of terms:
1) Nutrition – is the study of food in relation to health.
2) Food – is any substance when ingested or eaten nourishes the body.
3) Nutrient – is a chemical component needed by the body to provide energy, to
build and repair tissues and to regulate life process.
4) Digestion – it is a mechanical and chemical breakdown of food into smaller components.
5) Absorption – it is a process where the nutrients from foods are absorb by the body
into the bloodstreams.
6) Metabolism – is a chemical process of transforming foods into other substance to
sustain life.
7) Enzymes – an organic catalyst that are protein in nature and are produced by living cells.
A catalyst speeds up or slows down chemical reactions without itself
undergoing change.
8) Nutritional Status – is the condition of the body resulting from the utilization of
essential nutrients.
9) Calorie – fuel potential in a food. One calorie represents the amount of heat required
to raise one liter of water one degree Celsius.
10) Malnutrition – It is the condition of the body resulting from a lack of one or more
essential nutrients or due to excessive nutrient supply.
CHAPTER 1
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The Digestive System
• Mouth: The digestive process begins in the mouth. Food is partly broken down by the
process of chewing and by the chemical action of salivary amylase (these enzymes are
produced by the salivary glands and break down starches into smaller molecules).
On the way to the stomach:
• Esophagus – After being chewed and swallowed, the food enters the esophagus. The
esophagus is a long tube that runs from the mouth to the stomach. It uses rhythmic,
wave-like muscle movements (called peristalsis) to force food from the throat into the
stomach. This muscle movement gives us the ability to eat or drink even when we’re
upside-down.
• Stomach – The stomach is a large, sack-like organ that churns the food and bathes it in a
very strong acid (gastric acid). Food in the stomach that is partly digested and mixed
with stomach acids is called chyme.
• Small intestine – absorption happens in the small intestine. Bile (produced in the liver
and stored in the gall bladder), pancreatic enzymes, and other digestive enzymes
produced by the inner wall of the small intestine help in the breakdown of food.
• Large intestine – Undigested food passes in the large intestine. In the large intestine,
some of the water and electrolytes (chemicals like sodium) are removed from the food.
• The end of the process – Solid waste is then stored in the rectum until it is excreted via
the anus.
ENZYMES – an organic catalyst that are protein in nature and are produced by living cells.
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1. Amylase – carbohydrate splitters
2. Lipase – fat splitters
3. Proteases – protein splitters
Esophagus
Dextrin and
Maltose Dextrin, lactose,
Pancreatic sucrose, maltose
Amylase
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polypeptide Single chain
amino acids amino acid
Intestinal juice Aminopeptidase
(succus entericus)
long chain fatty Fatty acids
acids, glycerides,
Intestinal lipase cholesterol
maltose
Glucose
Isomaltase lactose
Glucose,
galactose
Lactase sucrose
Glucose, fructose
Sucrase
Large Intestine
CHO – 90%
Protein – 92%
Fats – 95%
Classification of Nutrients
1) According to function:
- Function as energy giving, body building, body regulating.
2) According to chemical properties:
a) Organic – protein, lipids, carbohydrates and vitamins
b) Inorganic – water & minerals
3) According to concentration
a) Macro nutrients – Carbohydrates, Protein, Fats
b) Micro nutrients – Vitamins, Minerals & water
CHAPTER 2
BASIC TOOLS IN NUTRITION
Food Groups –group of foods that have similar nutritional properties and is part of the
hierarchy of the food pyramid, such as cereal group, milk group, meat and protein
group, fruit and vegetable group, fats and sweets group .
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Dietary Guidelines strategies to promote appropriate diets and related health practices
to achieve the goal of improving the nutritional condition.
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FOOD GUIDE PYRAMID
(USDA) United States Dept. of Agriculture
MyPyramid contains eight divisions. From left to right on the pyramid are six food groups:
• Grains, recommending that at least half of grains consumed be as whole grains
• Vegetables, emphasizing dark green vegetables, orange vegetables, and dry beans and peas
• Fruits, emphasizing variety and deemphasizing fruit juices
• Oils, recommending fish, nut, and vegetables sources
• Milk,, a category that includes fluid milk and many other milk-based products
• Meat and beans, emphasizing low-fat and lean meats such as fish as well as more beans, peas,
nuts, and seeds
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- The word exchange refers to the fact that each item on a particular list in the portion
listed may be interchanged with any other food item on the same list. An exchange can
be explained as a substitution, choice, or serving.
Nutritional Labeling
- Primary means of communication between the
producer or manufacturer and the consumer.
CHAPTER 3
MACRO NUTRIENTS
Macro nutrients - constitute the bulk of the food we eat, they provide energy and
chemical building-blocks for tissues.
3 Macro Nutrients:
1. Carbohydrates
2. Protein
3. Fats
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CARBOHYDRATES
Classification of Carbohydrates
Simple Carbohydrates
1) Monosaccharide – “simple sugar”, is the simplest form of sugar.
a) Glucose – “blood sugar”
b) Fructose – sweetest of simple sugar. Found in honey, fruits and vegetables.
c) Galactose – not found in free foods. Galactose is a result when the lactose breakdown.
** Simple sugar are water soluble, and quickly absorb in the bloodstream ***
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e) Glycogen – “animal starch”
f) Hemicellulose – also indigestible, found in agar, pectin, woody fibers, leaves, stems.
g) Inulin – Important medicine and nursing as it provides test of renal function.
Functions of Carbohydrates:
1) Main source of energy for the body.
2) Protein sparing action
3) Necessary for normal fat metabolism
4) Cellulose stimulate peristaltic movement of the gastrointestinal tract. Absorb water to give bulk
to the intestines.
5) Lactose encourage the growth of beneficial bacteria, resulting in a laxative action.
6) Glucose is the sole source of energy in the brain. Proper functioning of the tissues
Sources of Carbohydrates
1) Whole grains
2) Sweet potatoes & white potatoes. Bananas, dried fruits.
3) Milk (lactose)
4) Sugar , sweets, honey, maple sugar
“Empty Calories” - foods which do not contain any other nutrients except carbohydrates
Common Diseases:
1. Overweight
2. Diabetes
3. Tooth Decay
4. Depressed appetite
5. Fermentation causing gas formation
6. Cancer
Deficiency
1)Ketosis – disease caused by lack of carbohydrates, in which the acid level of the body is raised
2)Protein _ Energy Malnutrition
a) Kwashiorkor – Protein Def.
b) Marasmus – Calorie Def.
3) Low Blood Sugar Level
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FATS or Lipids
- Fats, oils, and waxes belong to the group of naturally
occurring organic materials called
- lipids.
- Lipids are those constituents of plants or animals
which are insoluble in water but soluble in other
organic solvents.
Classes:
1) Omega 3 - have a positive effect on reducing mortality from cardiovascular disease.
Reduced blood clotting tendency and reduced blood pressure.
2) Omega 6 – “Linoleic acid” polyunsaturated fatty acid.
lowers cholesterol levels in the blood and helps in the prevention of heart disease.
Sources of Polyunsaturated fats : unrefined safflower, corn, sesame, soybean, sunflower oil,
seeds, nuts, dark green vegetables.
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Fatty Acid Composition of Common Food Fats
Functions:
1) Important source of calories to provide a continuous supply if energy.
2) Protein sparing
3) Maintain the constant blood temperature
4) Cushions vital organs such as kidney against injury
5) Facilitates the absorption of fat soluble vitamins (ADEK)
6) Provides satiety and delays onset on hunger.
7) Contributes flavor and palatability to the diet.
Cholesterol
Cholesterol is a major component of all cell membranes. It is required for synthesis of sex hormones,
bile acids, and vitamin D. It is also a precursor of the steroid hormones.
Cholesterol is also made in the body and is taken also thru foods
But Cholesterol is a major factor in the development of heart diseases
Daily intake should not exceed 300 mg./day
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• Richest: egg yolk, fish roes, mayonnaise and shell fish.
• Moderate : Fat on meat, duck, goose, cold cuts, whole milks, cream, ice cream, cheese, butter
and most commercially made cakes, biscuits and pastries.
• Poor : All fish and fish canned in vegetable oil, very lean meats, poultry without skin, skimmed
milk , low fat yoghurt and cottage cheese.
• Cholesterol free : All vegetables, and vegetable oils, fruit (including avocados and olives), nuts,
rice, egg white and sugar.
Vocabularies:
Lipid – Any of a group of organic compounds, including the fats, oils, waxes, sterols, and triglycerides,
that are insoluble in water but soluble in nonpolar organic solvents, are oily to the touch.
Fat - Any of various soft, solid, or semisolid organic compounds constituting the esters of glycerol and
fatty acids and their associated organic groups.
Oil – is liquid at room temperature soluble in various organic solvents such as ether but not in water
Cholesterol – is a form of fat in animal origin that is a factor in the development of heart disease.
Transfats - fatty acids that are produced when polyunsaturated oil are hydrogenated to make them
more solid. Thus raise the level of blood cholesterol.
Hydrogenated fats – unsaturated oil undergone hydrogenation to make them more solid and less
resistant to heat.
Low Density Lipoprotein (LDL) - A complex of lipids and proteins, with greater amounts of lipid than
protein, that transports cholesterol in the blood. High levels are associated with an increased risk of
atherosclerosis and coronary heart disease.
High Density Lipoprotein (HDL) - A complex of lipids and proteins in approximately equal amounts that
functions as a transporter of cholesterol in the blood. High levels are associated with a decreased risk of
atherosclerosis and coronary heart disease.
Sources of Fat
1) Animal Fats – fat from meat, fish, poultry, milk, milk products and eggs.
2) Vegetable Fats – margarine, seed and vegetable oil, nuts
3) Visible Fats – butter, cream, margarine, lard, fish liver oils, pork fat
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4) Invisible Fats – cheeses, olives, cakes, nuts, pastries
Diseases:
1) Heart Disease
2) Cancer
3) Obesity
PROTEIN
AMINO ACIDS
Amino acids are known as the building blocks of protein.
They perform many important functions such as: building cells, protecting the body from viruses or
bacteria, repairing damaged tissue and carrying oxygen throughout the body
There are 20 different amino acids. Amino acids are linked together to form peptides, which are
small chains of amino acids. The peptides are then linked together to form larger proteins.
There are thousands of different proteins that carry out a large number of jobs in the human body. Even
though so many different proteins are at work in your body, you don't have to worry about consuming
each individual protein from the foods you eat. Your body will make those proteins. All you need to do is
to make sure your body has a healthy supply of all 20 of the different amino acid "building blocks."
Having enough of those amino acids is easy because your body can make 11 of them from other
compounds already in your body. That leaves eight amino acids that you must get from your diet.
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Types of Amino Acids
1) Essential Amino Acids –are those that are necessary for good health but cannot be produced by the
body and so must be supplied in the diet.
Ex. Leucine, Isoleucine
Lysine, Valine
Typtophan, Phenylalanine,
Methionine Serine
2) Non-Essential Amino Acids –are those that are produced by the body so not as necessary in the
diet
Ex. Aspartic Acid Tyrosine Glycine
Cysteine Arginine
Glutamic Acid Histidine
Glutamine Alanine
Asparagine Proline
Functions of Proteins
1) Used in repairing worn out body tissue
2) Source of heat and energy
3) Contribute to numerous essential body secretions (mucus, milk, sperm cells)
4) Keeping fluids and pH balanced in the body
5) Play a large role in the resistance of the body to diseases
6) Contributing to enzyme activity that promotes chemical reactions in the body
7) Signaling cells what to do and when to do it
8) Transporting substances around the body
9) Serving as building blocks for hormone production
10) Helping blood clot
11) Serving as structural components that give our body parts their shapes
Sources:
Complete Protein
1. Meat – beef, pork, lamb
2. Poultry – chicken, turkey, duck
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3. Fish
4. Dairy Products – milk, yogurt, cheese
Incomplete Protein
Grains – beans, corn, oats, pasta, whole grain breads
Legumes, seeds & nuts – sesame seed, sunflower seed, peas, rice, peanuts, cashew
Vegetables – Brocolli
Common Diseases
1) Heart Disease
2) Cancer (prostate, pancreas, kidney, breast and colon)
3) Osteoporosis
4) Weight control
5) Kidney Diseases
6) Ketosis
Protein – Energy Malnutrition
CHAPTER 4
MICRO NUTRIENTS
VITAMINS & MINERALS
VITAMINS
• Complex organic compound to regulate body
processes and maintain body tissue
• “Vitamin” comes from the Latin word “vita”
meaning life, “amine” means nitrogen
compound.
• Vitamins do not give the body energy.
• Therefore, we cannot increase our physical
capacity by taking extra vitamins
• Vitamins do not have calorie value.
Vitamins Terminologies
• Precursor or Provitamins – these are compounds that can be changed to the active
vitamins
Ex. Carotene are precursors to Vit. A
• Preformed Vitamins – naturally occurring vitamins that are inactive form and ready for
its biological use.
Ex. Animal sources
• Avitaminosis – severe lack of vitamins
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Ex. Avitaminosis A leads to night blindness
• Hypervitaminosis – “vitamin toxicity”
excessive accumulation of vitamins in the body
• Vitamin Malnutrition – “too much or too little”
NOMENCLATURE OF VITAMINS
VITAMIN NOMENCLATURE
Vitamin A Retinol
D Calciferol
E Tocopherol
K Phylloquinone
Vitamin B1 Thiamine
B2 Riboflavin
B3 Niacin
B4 Panthotenic Acid
B6 Pyridoxine
B8 Biotin
B12 Cyanocobalamin
Vit. C Ascorbic Acid
Vit. A (Retinol)
FUNCTIONS
1) Vision Cycle – necessary component of visual purple (rhodopsia), a pigment to make
adjustments to light and dark.
2) Necessary material for maintenance of epithelial tissues.
3) Growth & Bone Development –
4) Reproduction – necessary for normal reproduction and lactation.
5) Antioxidant
Food Sources
1) Animal Sources – liver, yolk, milk, butter, cheese, fish, clams, tahong
2) Plant sources – deep green and yellow vegetables and fruits
DAILY DOSAGE:
Male – 1000 microgram
Female – 800 microgram
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Deficiency & Toxicity
Vitamin A (Retinol)
Deficiency
• Night blindness
• Eye lesions
• Retarded growth
• Lower resistance to infections
• Faulty skeletal & dental development
Skin Lesions
Toxicity
• Liver damage
• Mild dermatitis
• Thickening of the skin and peeling off
• Course sparse hair
• Hyper carotenimia
(harmless orange appearance
VIT. D (Calciferol)
Functions
1) Absorption of Calcium & Phosphorus
2) Essential for normal growth development.
Food Sources
1) Synthesis with sunlight (10 mins/day)
2) cod liver fish, halibut [type of flatfish], salmon, sardine, egg yolk
3) Fortified Vit. A products
Deficiency
• Tetany ( abnormal muscle twitching and cramps
• Rickets (defective bones, retarded growth)
• Osteomalasia
• ( softening of the bones)
Toxicity
• Stone formation on kidney
• Demineralisation of the bone
• Polyuria
• Weight Loss
• Hypercalcemia
Vit. E (Tocopherol)
Functions
1. Maintenance of cellular membrane
2. Anti oxidant
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Food Sources
Whole grain nuts, seeds, green and leafy vegetables, polyunsaturated fats
• No toxicity , this nutrient cannot be stored to a large extend in the body
Vit. K ( Phylloquinone)
Functions
Aids in blood clotting and bone mineralization
Food Sources
Green leafy vegetables, soy beans
• Deficiency
Hemmorhagic diseases
Toxicity
• Vomitting
• Albuminuria
• Hemolysis
FYI
• Anti oxidant - Any substance that reduces oxidative damage (damage due to oxygen) such as
that caused by free radicals.
• Free Radicals - are highly reactive chemicals that attack molecules by capturing electrons and
thus modifying chemical structures
• PHYTOCHEMICAL - natural bioactive compound found in plant foods that works with nutrients
and dietary fiber to protect against disease
Toxicity
Diarrhea, bloating, cramps, formation of kidney stones
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FOOD SOURCES
Citrus fruits, Brocolli, strawberries, potatoes, mangoes, papaya, red and green bell pepper,
Dark green vegetables
Vitamin B1 (Thiamine)
Functions
1. Helps release energy from foods,
2. Promotes normal appetite
3. Important in function of nervous system
Deficiency
1. Mental confusion; muscle weakness
2. wasting; edema; impaired growth; beriberi.
Toxicity (none)
None
Food Sources
pork, liver, whole grains, lean meats
Vit. B2 (Riboflavin)
Functions
1. Helps release energy from foods;
2. Promotes good vision, healthy skin
Deficiency
1. Cracks at corners of mouth;
2. Dermatitis around nose and lips;
3. Eyes sensitive to light.
Toxicity (none)
Food Sources
1. Liver, milk, dark green vegetables, whole and
2. enriched grain products, eggs
Vit. B3 (Niacin)
Functions
1. Energy production from foods;
2. Aids digestion, promotes normal appetite;
3. Promotes healthy skin, nerves
Deficiency
1. Skin disorders; diarrhea; weakness
2. mental confusion; irritability.
3. Pellagra
Toxicity
1. Abnormal liver function;
2. Nausea; irritability
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Food Sources
1. Liver, fish, poultry, meat, peanuts,
2. whole and enriched grain products.
Deficiency
Uncommon due to availability in most foods;
fatigue; nausea, abdominal cramps; difficulty sleeping.
Toxicity (none)
Food Sources
Liver, kidney, meats, egg yolk, whole grains, legumes
Vit. B6 (Pyridoxine)
Functions
Aids in protein metabolism, absorption;
Aids in red blood cell formation;
Helps body use fats.
Deficiency
Skin disorders, dermatitis
Cracks at corners of mouth;
Irritability; anemia; kidney stones;
Nausea; smooth tongue.
B8 (Biotin)
Functions
Helps release energy from carbohydrates
Aids in fat synthesis.
Deficiency
Fatigue; loss of appetite, nausea, vomiting;
Depression; muscle pains; anemia.
Toxicity – none
Food Sources
Liver, kidney, egg yolk, milk,
Fresh vegetables
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Minerals
What is a mineral?
Minerals are elements that are not organic needed by the body in relatively small amounts to help
regulate body process and maintain tissue structure
• Minerals do not broken down during digestion nor destroyed by heat or light.
Primary Roles:
• Metabolic health
• Anti oxidant
• Blood health
• Bone health
• Electrolyte balance
Major Minerals:
1) Calcium
2) Phosphorus
3) Magnesium
4) Potassium
5) Sodium
6) Chloride
Trace Minerals:
1) Iron
2) Iodine
3) Zinc
4) Flouride
5) Selenium
6) Manganese
7) Chromium
Major Minerals
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convulsion, green leafy veg,
muscle spasm fish with bones
Trace Minerals
WATER
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• Most important nutritional constituent is
water
• The major component of the body is
water
• 60 – 70% water
• Water has no nutritional values and no
calories
• Water is necessary to transport nutrients
• regulate body temperature
• Remove waste materials
• Participate in chemical reaction & energy
production
CHAPTER 5
Basal Metabolism –the amount of energy required by an individual in the resting state, for such
functions as breathing and circulation of the blood.
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Basal Metabolic Rate – the minimum caloric requirement needed to sustain life in a resting
individual. It can be looked at as being the amount of energy (measured in calories) expended
by the body to remain in bed asleep all day.
1.Genetics. Some people are born with faster metabolisms; some with slower metabolisms.
2. Gender. Men have a greater muscle mass and a lower body fat percentage. This means they
have a higher basal metabolic rate.
3. Age. BMR reduces with age. After 20 years, it drops about 2 per cent, per decade.
4. Weight. The heavier your weight, the higher your BMR. Example: the metabolic rate of obese
women is 25 percent higher than the metabolic rate of thin women.
5. Body Surface Area. This is a reflection of your height and weight. The greater your Body
Surface Area factor, the higher your BMR. Tall, thin people have higher BMRs. If you compare a
tall person with a short person of equal weight, then if they both follow a diet calorie-controlled
to maintain the weight of the taller person, the shorter person may gain up to 15 pounds in a
year.
6. Body Fat Percentage. The lower your body fat percentage, the higher your BMR. The lower
body fat percentage in the male body is one reason why men generally have a 10-15% faster
BMR than women.
7. Diet. Starvation or serious abrupt calorie-reduction can dramatically reduce BMR by up to 30
percent.Restrictive low-calorie weight loss diets may cause your BMR to drop as much as 20%.
8. Sleep – BMR falls 10-15% below waking levels.
9. Endocrine Glands – male sex hormones increase the BMR 10-15%
10. Fever – increase 7% for each degree rise the body temperature above 98.6 F
COMPUTATION:
3. DBW
A . (TANHAUSSER’S METHOD) FOR ADULT
DBW = ( Ht. cm – 100 ) – 10%
Ex. 5‘3“ = (63 inches x 2.54) = (160.02 – 100) = (60.02- 6.002 [10%]) = 54 kg.
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B. Infants: (0-6 months)
a) DBW = birth weight (gms)+(age in mons.x 600)
Note: if the weight is not known, use 3000 gms.
Example: 4 month old infant
DBW = 3000 + (4 x 600)
= 3000 + 2400
= 5400 gms or 5.4 kg.
b) DBW = (age in months ÷ 2) + 3
Ex: DBW = (4÷2) + 3 = 2 + 3
= 5 kg.
CONVERSION:
HT. WT.
1 ft. = 12 inches 1 kg. = 2.2 lbs
1 inch = 2.54 cm
100 cm = 1 meter
ACTIVITY LEVEL :
Bed rest = 27.5 (hospital patients)
Sedentary = 30 (secretary, clerk, typist administrator, cashier, bank teller)
Light = 35 ( teacher, nurse, student, Lab.Tech, house wife with maid)
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Moderate = 40 ( housewife w/o a maid, vendor, mechanic, jeepney & car driver)
Heavy = 45 ( farmer, laborer, cargador, laborer, coal miner, fisherman, heavy eqpt.optr )
BMI LEVEL:
Obese = above 30
Overweight = 27-30
Normal = 18.5 – 27
Under weight = below 18
4. DIET PRESCRIPTION:
Percentage Distribution
CHO 50-70%
60% (average)
PRO 10% (infant/children)
10-15% (adolescent/adult)
FAT 20-25% (adult)
30-35% (children)
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V Meat
Low Fat Varies - 8 1 41
Medium Fat - 8 6 86
High Fat - 8 19 122
VI Fat 1 tsp. - - 5 45
VII Sugar 1 teaspoon 5 - - 20
FOOD DISTRIBUTION
341 84 62
2,190
MEAL DISTRIBUTION
FOOD BFAST LUNCH DINNER AM SNACK PM SNACK
Veg A 1 1 1
Veg B 1 1 1
FRUIT 1 1 1 1 1
MILK 1
RICE 2 2 2 2 2
MEAT 2 1 1 1 1
FAT 1 1 1
SUGAR 1 1 1 1
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CHAPTER 6
NUTRITIONAL ASSESSMENT
What is Nutritional Assessment?
is an in-depth evaluation of both objective and subjective data related to an individual's
food and nutrient intake, lifestyle, and medical history.
Methods of Assessment:
) Direct Assessment – based on physical sign
a) Diet History – This method evaluates the primary factor of nutritional inadequacy.
b) Physical Method or Anthropometric– Taking weight & height data
c) Medical History – record of the person’s
past illnesses
d) Clinical Examination – physical signs associated with malnutrition
e) Biochemical Tests – blood plasma, tissue biopsy, urinalysis
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5. Cultural and anthropological influences
6. Socio economic factors- population, family, education
7. Food production -
8. Health and educational services
1. 24 Hr. Recall – recall of all what he/she had eaten within 24 hrs.
2. Food Frequency Questionnaire
3. Diet History
- It is more complete than the two previous method. It contains the following:
Economic ( income, amount of money for food)
Physical Activity (occupation, exercise, sleep)
Ethnic & Cultural Background (religion, educ)
Home life & Meal Patterns (no.per household,
person who does the cooking, type of house)
Appetite (good, poor)
allergies, intolerances, food avoidance
Dental/Oral health
Gastrointestinal ( heartburn, diarrhea, constipation)
Chronic Diseases
Medication
4. Food Diary - The subject is asked to write down everything that he eats for
a certain time. It could be 3 days, two weeks
5. Observation of food intake – most accurate but most time consuming.
It requires knowing the amount and kind of food presented and the record
of the amount actually eaten.
CHAPTER 7
MALNUTRITION
Malnutrition – It is the condition of the body resulting from a lack of one or more
essential nutrients or due to excessive nutrient supply.
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2 Conditions of Nutritional Status
1) Optimum or Good Nutrition – body has adequate supply of essential nutrients for growth &
health
2) Malnutrition – A condition of the body resulting from a lack of one or more nutrients or it may be
due to an excessive nutrient supply creating toxic or harmful effects
Forms of Malnutrition
1. Under nutrition – resulting fro inadequate quantity of food, over an extended period of time
(kwashirkor, marasmus)
2. Specific Deficiency – resulting from a relative or absolute lack of an individual nutrient ( iron
deficiency)
3. Over nutrition – resulting from the consumption of an excessive quantity of food, calorie excess
(obesity)
4. Imbalance – resulting from a disproportion among essential nutrients, with or with out absolute
deficiency of any nutrient.
Types of Malnutrition
1. Acute Malnutrition- related to present state nutrition
ex. Loss of weight
2. Chronic Malnutrition – related to the past state of nutrition
3. Primary Malnutrition – caused by lack or unavailability of food (dietary malnutrition)
4. Secondary Malnutrition – caused by certain conditioning factors other than food alone
Nutritional Deficiencies
2. Secondary Factors:
a) Interfere with normal digestion
1. Gastrointestinal disorder
2. Lack of appetite
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3. Poor teeth
4. Lack of digestive enzymes
b) Factors that interfere with absorption
1. Diarrhea
2. Mal absorption Syndrome
3. Intestinal Surgery
4. Laxative
5. Parasitism
Effects of Malnutrition
Prevention:
1) Increase economic stability
2) Educate the people
3) Practice good sanitation and hygiene
4) Increase food production
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5) Eat balance diet
6) Exercise
7) Social Awareness ( thin is not “in”)
CHAPTER 8
FOOD & DRUG INTERACTION
Introduction
Medications, both prescription and over-the-counter, are used every day to treat acute and chronic illness. Research
and technology constantly improve the drugs we have available and introduce new ones. Medications can help
people live healthy lives for a prolonged period. Although medicines are prescribed often, it is important to realize that
they must still be used with caution.
Foods, and the nutrients they contain, can interact with medications we take. This can cause unwanted effects. A
food/drug interaction occurs when a food, or one of its components, interferes with the way a drug is used in the
body. A drug/nutrient interaction occurs when a drug affects the use of a nutrient in the body.
Risk Factors
Risk for food/drug and drug/nutrient interactions can be affected by many factors such as:
age
gender
medical history
body composition
nutritional status
number of medications used
Stage 3. The body responds to the drug and the drug performs a function.
Stage 4. The drug is excreted from the body either by the kidney or the liver, or both.
Not all medications are taken by mouth. Still, they are all transported to the site of action. Effects of drug/nutrient and
food/drug interactions vary according to:
type of medication
form of drug (pill, liquid, etc.)
dosage
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site of absorption (mouth, stomach, intestine)
route of administration (oral, intravenous, etc.).
Definitions
Absorption: the passage of substances from the GI tract into the blood.
Food/Drug Interactions
Foods can interfere with the stages of drug action in a number of ways. The most common effect is for foods to
interfere with drug absorption. This can make a drug less effective because less gets into the blood and to the site of
action. Second, nutrients or other chemicals in foods can affect how a drug is used in the body. Third, excretion of
drugs from the body may be affected by foods, nutrients, or other substances.
With some drugs, it's important to avoid taking food and medication together because the food can make the drug
less effective. For other drugs, it may be good to take the drug with food to prevent stomach irritation.
Alcohol can affect many medications. Always check with your pharmacist about possible effects of alcohol on your
medication.
It's best to not take medications with grapefruit juice. Drink it at least two hours away from when you take your
medication. If you often drink grapefruit juice, talk with your pharmacist or doctor before changing your routine.
Drug/Nutrient Interactions
It is also possible for drugs to interfere with a person's nutritional status. Some drugs interfere with the absorption of a
nutrient. Other drugs affect the body's use and/or excretion of nutrients, especially vitamins and minerals. If less of a
nutrient is available to the body because of these effects, this may lead to a nutrient deficiency.
Sometimes drugs affect nutritional status by increasing or decreasing appetite. This affects the amount of food (and
nutrients) consumed. Some specific examples of drug/nutrient interactions are given in Table 2.
The Different Groups of Medicines
Drugs are grouped into classes based on illnesses for which they are prescribed. They can also be grouped in other
ways, such as their chemical make-up or actions in the body. Different foods can interact with more than one class of
drugs.
Table 3 is a list of 14 drug classes and the uses for each. If you take medication in one of these classes, be aware of
potential food/drug and drug/ nutrient interactions. If you aren't sure which classes your medicines fall into, ask your
doctor or pharmacist.
Analgesic
Analgesics are drugs that relieve pain. Analgesics often cause stomach irritation. It's a good idea to take analgesics,
like aspirin, with food. A full stomach lowers the risk for stomach irritation.
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Antacid, Acid Blocker
Antacids neutralize stomach acid, and acid blockers reduce stomach acid production. Long term use of these drugs
may lead to certain nutrient deficiencies. This is because stomach acid is important in the digestion and/or absorption
of nutrients.
Older people produce less stomach acid, which leads to low absorption of vitamin B 12 . Regular use of antacids or
acid blockers lowers vitamin B 12 absorption even more. Vitamin B 12 supplements may be needed in this situation.
Antibiotic
Antibiotics are used to treat bacterial infections. There are many different types of antibiotics. Some antibiotics
decrease the synthesis of vitamin K by the bacteria normally found in our intestines. Vitamin K is important for normal
blood clotting.
Tetracycline antibiotics bind to calcium found in dairy products. This can decrease the absorption of the antibiotic.
Other drugs like penicillin and erythromycin are most effective when taken on an empty stomach. This is because
they may be partially destroyed by stomach acid when taken with food. However, food can reduce the chance of
stomach irritation from these drugs. Ask your pharmacist if you should take your antibiotic with or without food.
Anticoagulant
Anticoagulants slow the process of blood clotting. This can decrease risk of strokes in patients whose blood tends to
clot too easily. These drugs, like warfarin (Coumadin), work by interfering with the use of vitamin K in blood clotting.
People taking these anticoagulants should be consistent in the amount of vitamin K they get from foods. It's very
important to avoid eating large amounts of foods high in vitamin K. Rich sources of vitamin K include liver, and green
vegetables such as broccoli, spinach, and other leafy greens.
Anticonvulsant
Anticonvulsant drugs help control seizures. Phenytoin (Dilantin), phenobarbital, and primidone may cause diarrhea
and a decrease in appetite. This can decrease the availability of many nutrients.
These drugs also increase the use of vitamin D in the body. This means that less vitamin D is available for important
functions such as calcium absorption. Vitamin D supplements may be needed.
Some anticonvulsants also interact with the B vitamin folic acid. When drug therapy is started, folic acid levels in the
body decrease. Because folic acid supplements affect blood levels of the drug, folate supplementation must be
supervised by a doctor.
Antihistamine
Antihistamines are used to treat allergies. Many of these drugs often cause drowsiness. They may also increase the
appetite, which can lead to weight gain. Increased physical activity can help reduce weight gain. Alcohol can cause
an even greater increase in drowsiness caused by antihistamines like diphenhydramine (Benadryl),
chlorpheniramine (Chlor-Trimeton), and other over-the-counter drugs containing antihistamines.
Anti-inflammatory
Anti-inflammatory medication is prescribed to patients for a number of problems such as chronic joint pain,
headaches, and arthritis. Long-term use may lead to stomach irritation and eventually ulcers. These medications
should be taken with food.
Cancer Drugs
Antineoplastic agents are used to treat different forms of cancer. These drugs can irritate the cells lining the mouth,
stomach, and intestines. Many cause nausea, vomiting, and/or diarrhea. All of these can affect nutrient status.
Methotrexate reduces availability of the B vitamin folic acid. Supplementation of folate may be recommended for
people taking this drug, but ask your doctor before starting folic acid.
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Diuretic
Diuretics cause the body to excrete more urine and are often used to treat high blood pressure. Some diuretics
increase urine losses of minerals such as potassium, magnesium, and calcium. Others limit mineral loss (especially
potassium). It is important to talk with your doctor about whether you need to take or avoid mineral supplements.
Laxative
Laxatives speed up the movement of materials through the digestive tract. This reduces the time for nutrient
absorption. Excessive use of laxatives can deplete vitamins and minerals needed for normal body function. Laxatives
also increase fluid losses. This may lead to dehydration.
Always carry a list of all your medications and the dosing instructions.
When your doctor prescribes a new medication, tell him/her all the other drugs you already take. This includes
over-the-counter drugs and supplements that you use regularly. Also, remind your doctor about any drug
allergies you have.
Know how and when to take all of your medications. If you have any questions, ask your doctor or pharmacist.
If you have any side effects from a medication, contact your doctor or pharmacist immediately. Do not wait until
your next appointment. If you are not sure if symptoms are related to your medication, be sure to ask.
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It is usually best to take medication with a full glass of water. This may help to prevent stomach irritation and
improve absorption. Don't take medications with soft drinks or grapefruit juice.
Get your prescription refilled before you run out so that there are no missed doses.
Don't stir your medication into food or drink unless your doctor or pharmacist tells you to. Certain foods may
break down the drug, or limit its absorption.
Always read the directions and warning labels on your medication bottles and packages. If you don't understand
something, ask your doctor or pharmacist.
Table 1.
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Diuretic
Decreases GI
spironolactone Food Take with food
irritation
(Aldactone)
Psychotherapeutic
MAO inhibitors: Foods high in tyramine: aged
isocarboxazid (Marplan), cheeses, Chianti wine, Risk for Avoid foods high in
tranylcypromine pickled herring, Brewer's hypertensive crisis tyramine
(Parnate), yeast, fava beans
phenelzine (Nardil)
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Anticonvulsant Seizures, epilepsy
Antihistamine Allergies
Antihyperlipemic High blood cholesterol
Antihypertensive High blood pressure
Anti-inflammatory Fever, inflammation
Antineoplastic Cancer
Diuretic Water retention
Laxative Constipation
Psychotherapeutic Depression, anxiety
CHAPTER 8
NUTRITION IN THE LIFE CYCLE
PREGNANCY
• Nutrition in Pregnancy:
• During the total pregnancy period, the basal metabolic rate increase from 6-14%
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• Calorie intake is increased – 10-20% increase ( if the woman is overweight it is necessary for her
o reduce)
• Protein - Increase in nitrogen content of the fetus and its membranes and added protection of
the mother against complications
• Increase of 9.5 gms./ day
• Calcium / Phosphorus / Vit. D – Increase , to calcify the fetal bones & teeth (0.5 – 0.9 of the
RDA)
• Iron – Increase, 700-1000 mg. of Fe is absorbed during the pregnancy
• Iodine – to help the mother and the child prevent goiter in the future and for brain
development
• Folic Acid - women of childbearing age consume 400 micrograms (0.4 mg) of folic acid each day.
Folic acid, a nutrient found in some green, leafy vegetables, most berries, nuts, beans, citrus
fruits, fortified breakfast cereals, and some vitamin supplements can help reduce the risk of
birth defects of the brain and spinal cord (called neural tube defects).
LACTATION
• Calories – additional 1000 calories –
help to produce milk
• Protein – additional of 20 gms. , to
compensate the protein lost in milk
• Calcium & Phosphorous – Increase of
0.5 mg., to prevent severe depletion
of maternal calcium for milk
production
• Iron – additional intake is
recommended for blood lost
• Vit. A – additional 2000 IU, needed in
the ilk secretion
• Riboflavin, Vit. C – increase
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2. Nutritional State of Mother – Malnutrition and illnesses (cardiac and kidney diseases, anemia,
beri-beri, tuberculosis) can lessen the quanity and quality of milk
• Emotional & Physical State – relax, pleasant surroundings, lots of rest and good sleep
• Suckling - suckling right after delivery stimulate milk secretion
• Contraceptives & Drugs – depress milk flow
Milk Formula:
A) Whole Cows Milk Formula
1. Powdered whole cow’s milk – milk dried under controlled condition
(Nido, Birch Tree, Anchor Mik)
2. Full Cream evaporated Milk – whole milk from which 50-60% of water content has been
removed
3. Recombined milk – skim milk powder reconstituted to normal fat content of the whole milk
by adding butterfat
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4.Reconstituted milk – process milk to which water is added to restore its original water content
(Frisian Girl, Alpine)
Note: goat’s milk has also been found effective as hypo allergenic milk
• This is the most difficult stage in feeding a child since the appetite tapers off corresponding to
the lower rate of growth.
Foods to Give the Pre-School Child:
1) Mildly flavored foods
2) Plain foods is acceptable than mixed foods.
3) Fruits, puddings, custard, ice cream and gelatin may be given
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Sign of Good Nutrition in Pre-School Child
– Alert, vigorous and happy
– Endurance during activities
– sleeps well
– Normal height and weight for age
– Stands erect, arms and legs straight
– Clear, bright eyes, smooth healthy skin, lustrous hair
– Firm and well developed muscles
– Not irritable and restless
– Good attention
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• Long standing dietary habits
• Loss of teeth
• Loss of taste and smell
• Loss of neuromuscular coordination
• Physical discomfort
• Economic consideration
• Social Factors
• Psychological factors
Diet Recommendation
1. Eat good breakfast to start the day
2. Eat 4-5 light meals a day
3. Include essential foods (fish, vegetables, fruits)
4. Eat leisurely in pleasant surroundings
5. Eat the heaviest at noon
6. Avoid fatty foods
7. Avoid coffee
8. Drink hot milk before going to bed
CHAPTER 7
DIET THERAPY
Purpose of Diet Therapy:
1. To maintain or restore good nutritional status
2. To correct nutritional deficiencies which may occurred
3. To afford rest to a particular organ
4. To adjust the diet to the ability of the body to metabolize the nutrients
5. To bring about the changes in the body weight
Therapeutic Diet:
A. Modification in Consistency
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Liquid Diet
1. Clear Liquid Diet
Indication : surgery, inflammatory on GI Tract, necessary to minimize fecal material
Food Selection : clear, fat-free broths, strained juices, tea, black coffee, gelatin, hard
candies, give small amount every 1-2 hrs
2. Full Liquid Diet
Indication : Post operative, acute infection, impaired chewing and swallowing,
mouth
Surgery
Food Selection: strained cream soups, pureed fish and juices, plain gelatin, plain ice
cream, custard, milk & mild drinks, 6-8 frequent feeding.
Soft Diet
Patients who are unable to chew, swallow or digest foods
2. Bland Diet
Indications: Gastric, Doudenal ulcers, gastritis, ulcer, cardiac cases
Food Selections: mild in flavor, no coarse fiber and tough connective tissue
Avoided: Black pepper, chili powder, strong coffee, alcohol
3. Mechanical Soft
Indications : Poor dentures, lack of teeth, sores & lesions in the mouth
Spastic constipation, diverticulisis, other gastro-intestinal disturbances
Food Selections : full diet but reduced amount (grinding, chopping, mincing)
B. Modification in Composition
3. High Carbohydrates
Indications : renal & liver disturbances, toxemia of pregnancy, Addisons's disease
Food Selections -Emphasize on rice and other cereals, root crops, noodles, sugar, native cakes
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4. Low Carbohydrates
Indications : Hyperinsulinism, dumping syndrome, obesity, epilepsy, celiac disease
Food Selections : Foods high in protein, adequate to high fat foods, in certain conditions
5. High Protein
Indications : Growth, pregnancy, malnutrition, lactation, burns, surgery, fractures,
anemia, hepatitis, cirrhosis, hyperinsulinism
Food Selections : With emphasis on meat, milk, eggs, cheese, poultry
6. Low Protein
Indications : Acute glomerunephritis, uremia, hepatic coma
Food Selections : Avoided: protein foods in excess amounts, limit the intake of legumes, nuts
7. Zero Protein
GENERAL USAGE
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TPN is administered by:
Complications:
ENTERAL FEEDING:
Enteral Feeding – delivery of food and nutrients either orally or by tube feeding directly into
GIT.
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Types of Enteral Feeding
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• Nasogastric intubation is a medical process
involving the insertion of a plastic tube
through the nose, past the throat, and
down into the stomach.
• Use to treat anorexia nervousa
Complications:
1. Mechanical
a) Nasopharyngeal irritation
b) Luminal obstruction
c) Mucosal erosions
d) Tube displacement
e) Aspiration
2) Gastrointestinal
a) cramping/distention
b) vomiting/diarrhea
c) costipation
3) Metabolic
a) Hypertonic dehydration
b) Glucose intolerance
c) Cardiac failure
d) Renal failure
e) Hepatic ecephalopathy
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