OUR LADY OF FATIMA UNIVERSITY

College of Nursing – Pampanga

Bachelor of NELL JOSHUA B. PANTIG

PROGRAM Science in STUDENT NAME
Nursing
YEAR AND SECTION BSN 2 Y1-16
COURSE NCMA 217 INSTRUCTOR Kenneth Manalang
DATE 6/13/23

NAME OF THE MECHANISM OF ACTION DOSAGE INDICATIONS CONTRAINDICATIONS ADVERSE EFFECT NURSING ALERT
DRUG
Misoprostol, the active ● Prevention of ● Known GI: ● Patient Education: Provide
Generic Name: ingredient in Cytotec, is a NSAID-induced gastric hypersensitivity to Nausea,diarrhea, abdominal comprehensive patient education
misoprostol synthetic prostaglandin E1 ulcers: Cytotec is misoprostol or pain, flatulence, regarding the medication, including
analog. It acts by binding to indicated for the prostaglandins. vomiting,dyspepsia,constipation the purpose, dosage regimen,
Brand Name: specific prostaglandin receptors prevention of gastric potential side effects, and signs of
Cytotec in the gastrointestinal tract and ulcers caused by ● Pregnancy beyond GU: complications. Ensure that the
uterus, resulting in various non-steroidal the first trimester Miscarriage, excessive bleeding,
patient understands the importance
Classifications effects: anti-inflammatory in the case of spotting,cramping,
of adhering to the prescribed dosage
drugs (NSAIDs) in medical abortion. hypermenorrhea,menstrual
Therapeutic Class: Gastrointestinal protection: patients at high risk, disorders,dysmenorrhea and reporting any concerns to the
Gastrointestinal mucosal Misoprostol increases the including those with a ● In women with a healthcare provider.
protective agent production of protective mucus, history of ulcers or history of uterine ● Other: ● Administration: Instruct the patient
inhibits gastric acid secretion, gastrointestinal surgery or Headache on the proper administration of the
Pharmacologic Class: and promotes bicarbonate and complications cesarean delivery oral tablets and emphasize the need
Prostaglandin E1 analog blood flow to the gastric associated with NSAID in the case of to follow the prescribed schedule.
mucosa, reducing the risk of use.
cervical ripening or ● Pregnancy Testing: Confirm the
NSAID-induced ulcers. ● Medical abortion: absence of pregnancy before
induction of labor.
Cytotec is used in initiating therapy with Cytotec for
Uterine contractions: combination with indications such as prevention of
Misoprostol induces uterine mifepristone or
NSAID-induced ulcers or off-label
contractions by stimulating methotrexate for
use.
myometrial activity, which is medical abortion
● Contraception: Advise women of
utilized in medical abortion and (termination of
cervical ripening/induction of pregnancy) within the childbearing potential to use reliable
labor. first trimester. contraception during and after
 ● Cervical ripening and therapy with Cytotec, as it can cause
induction of labor: fetal harm and should not be used
Cytotec can be used during pregnancy.
off-label for cervical ● Monitoring and Reporting: Monitor
ripening (softening the patient for adverse effects and
and dilation of the promptly report any concerns to the
cervix) and induction
healthcare provider.
of labor in specific
● Follow-up and Evaluation: Schedule
clinical situations.
appropriate follow-up visits or
assessments to evaluate the patient's
response to therapy and monitor for
any complications or the need for
further interventions.

Comerford, K. C., & Durkin, M. T. (2021). Nursing 2021 drug handbook. 41st edition. Philadelphia, Wolters Kluwer.