Classification and Indication and Side Effect or Adverse

Name of Drug Special Precautions Nursing Responsibility

Mechanism of Action Contraindication Effect

Generic Name: Classification: Indication: Adverse reactions: Use cautiously in:  Observe 10
Pantoprazole Rights of giving
Proton Pump Inhibitor Erosive esophagitis CNS: dizziness, headache  Severe hepatic medications
Brand: Protonix caused by gastro disease  Assess for
Mechanism of Action: esophageal reflux CV: chest pain  Atrophic gastritis
Dosage: 40 mg symptomatic
disease (GERD) with long term improvement
Reduces gastric acid EENT: rhinitis
Route: Per Orem secretion and increases use  Monitor blood
Contraindication:
gastric mucus and GI: vomiting, diarrhea,  Increased risk of glucose level in
Frequency: 30 min before bicarbonate production, Hypersensitivity to drug abdominal pain, dyspnea osteoporosis- diabetic patient
breakfast creating protective or any substituted related hip, wrist,  Explain that
Metabolic: or spine fractures
coating on gastric benzimidazole antacids don’t
Timing: 5:30 AM hyperglycemia with long-term
mucosa. affect drug
Musculoskeletal: hip, use or multiple absorption.
wrist, spine fractures daily doses  As appropriate,
(with long term daily  Concurrent use of review all other
use) atazanavir, significant
nelfinavir, or adverse reactions
Skin: rash, pruritus methotrexate and interactions,
 Pregnant or especially those
breastfeeding related to the
patients drugs and tests
 Children mentioned above.
 Classification and Indication and Side Effect or Adverse
Name of Drug Special Precautions Nursing Responsibility
Mechanism of Action Contraindication Effect

Generic Name: Classification: Indication: Adverse reaction: Use cautiously in:  observe 10
Clindamycin Rights of giving
Lincosamide Severe infections caused GI: nausea, vomiting,  renal or hepatic medication
Brand: Clindal by sensitive organisms diarrhea, abdominal pain, impairment  Assess for signs
Mechanism of Action: (such as Bacteroides esophagitis, pseudo  known alcohol
Dosage: 300 mg and symptoms of
fragilis, Clostridium membranous colitis intolerance hypersensitivity
Inhibits protein synthesis
perfringens,  pregnant patients reactions,
Route: IV in susceptible bacteria at Hematologic:
Fusobacterium,  neonates including
level of 50S ribosome, neutropenia, leukopenia,
Frequency: Q6H pneumococci, staphylo anaphylaxis.
thereby inhibiting peptide agranulocytosis,
cocci, and streptococci)
Timing: 6-12-6-12
bond formation and thrombocytopenia  Assess for
causing cell death Contraindication: purpura diarrhea and
signs and
Hypersensitivity to drug Hepatic: jaundice, symptoms of
or lincomycin hepatic dysfunction colitis.
 Tell patient that
Skin: maculopapular I.V. use may
rash, generalized cause bitter taste.
morbilliform-like rash Reassure him
Other: bitter taste (with that this effect
I.V. use), phlebitis at I.V. will resolve on
site, induration and its own.
sterile abscess (with I.M.
use), anaphylaxis
 Classification and Indication and Side Effect or Adverse
Name of Drug Special Precautions Nursing Responsibility
Mechanism of Action Contraindication Effect

Generic Name: Classification: Indication: Adverse reaction: Use cautiously in:  Observe 10 Rights
Amlodipine of giving
Calcium Channel Essential hypertension, CNS: headache,  aortic stenosis, medication
Brand: Norvasc Blocker chronic stable angina dizziness, drowsiness, severe hepatic  Monitor patient for
pectoris, and vasospastic light-headedness, fatigue, impairment, heart worsening angina.
Dosage: 5 mg Mechanism of Action: angina ( Prinzmetal’s weakness, lethargy failure  Monitor heart rate
angina)  elderly patients and rhythm and
Route: per orem Inhibits influx of CV: peripheral edema, blood pressure,
extracellular calcium  pregnant or
Contraindication: angina, bradycardia, especially at start of
Frequency: OD ions, thereby decreasing breastfeeding
hypotension, palpitations therapy.
myocardial contractility, Hypersensitivity to drug patients  Assess for heart
Timing: 8  children.
relaxing coronary and GI: nausea, abdominal failure; report signs
vascular muscles, and discomfort and symptoms
decreasing peripheral (peripheral edema,
resistance Musculoskeletal: muscle dyspnea) to
cramps, muscle pain or prescriber
inflammation promptly.
 Give sublingual
Respiratory: shortness of nitroglycerin, as
breath, dyspnea, prescribed, if
wheezing patient has signs or
symptoms of acute
Skin: rash, pruritus, myocardial
urticaria, flushing infarction
(especially when
dosage is
increased).
 Classification and Indication and Side Effect or Adverse
Name of Drug Special Precautions Nursing Responsibility
Mechanism of Action Contraindication Effect

Generic Name: Classification: Indication: Adverse reactions Use cautiously in:  Observe 10
Telmisartan Rights of giving
Angiotensin II receptor  Hypertension CNS: dizziness,  heart failure, medication
Brand: Micardis antagonist  Cardiovascular risk headache, fatigue impaired renal  Monitor blood
reduction function pressure
Dosage: 40mg Mechanism of Action: CV: chest pain, secondary to
peripheral edema, frequently and
Contraindication: primary renal
Route: per orem Inhibits vasoconstricting hypertension, watch for signs
effects and blocks disease or renal and symptoms of
Hypersensitivity to drug or intermittent claudication
Frequency: aldosterone-producing stenosis, hypotension.
its components
effects of angiotensin II EENT: sinusitis, obstructive  Closely monitor
Timing: biliary disorders,
at various receptor sites, pharyngitis patient with
including vascular hepatic impaired hepatic
smooth muscle and GI: nausea, vomiting, impairment, or renal function.
adrenal glands diarrhea, dyspepsia, volume or Correct volume
abdominal pain sodium depletion deficits as
 patients receiving appropriate
GU: urinary tract high-dose
infection before therapy
diuretics starts. Monitor
Musculoskeletal:  concomitant use fluid intake and
myalgia, back and leg of ACE output and
pain inhibitors and creatinine level
angiotensin during therapy.
Respiratory: cough, receptor blockers
upper respiratory (avoid use)
infection  pregnant or
breastfeeding
Skin: ulcer patients
Other: pain, flu or flulike  children younger
symptoms, than age 18
hypersensitivity (safety not
 established).

Classification and Indication and Side Effect or Adverse

Name of Drug Special Precautions Nursing Responsibility
Mechanism of Action Contraindication Effect

Generic Name: Classification: Indication: Adverse reactions Use cautiously in:  Observe 10
Piperacillin Tazobactam Rights of giving
Penicillin (extended-  Community- CNS: headache,  heart failure, medication
Brand: Tazocin, Zosyn spectrum), beta- acquired insomnia, agitation, renal  Assess neurologic
lactamase inhibitor pneumonia; dizziness, anxiety, insufficiency (in status, especially
Dosage: 4.5 IV ruptured appendix; lethargy, hallucinations, children),
Mechanism of Action: for seizures.
peritonitis; pelvic depression, twitching, seizures, bleeding
Route: IV  Monitor vital
inflammatory coma, seizures disorders,uremia,
Piperacillin inhibits signs and fluid
Frequency: Q6H ANST bacterial cell wall disease; skin and hypokalemia, intake and output.
skin- structure CV: hypertension, chest cystic fibrosis
Timing: 8-2-8-2
synthesis, resulting in pain, tachycardia  Evaluate
cell death. Tazobactam infections  patients with electrolyte levels,
increases piperacillin  Nosocomia EENT: rhinitis, glossitis sodium CBC with white
efficacy. pneumonia restrictions cell differential,
GI: nausea, vomiting,  pregnant or and culture and
Contraindication: diarrhea, constipation, breastfeeding sensitivity tests.
dyspepsia, abdominal patient Watch for
 Hypersensitivity to
penicillins,
pain,  children younger evidence of
pseudomembranous than age 12 hypokalemia and
cephalosporins,
colitis (safety and blood dyscrasias.
imipenems, or beta-
lactamase inhibitors GU: proteinuria, efficacy not  In patients
established). receiving high
 Neonates hematuria, vaginal
candidiasis, vaginitis, doses or
oliguria, interstitial prolonged
nephritis, therapy, monitor
glomerulonephritis for signs and
symptoms of
Hematologic: anemia, bacterial or
increased bleeding, bone fungal
marrow depression superinfection
leukopenia, and
thrombocytopenia pseudomembranu
s colitis.
Metabolic: hypokalemia,  Monitor patient’s
hypernatremia dietary sodium
Respiratory: dyspnea intake (drug has
high sodium
Skin: rash, pruritus content).
 Immediately
Other: fever; pain, report rash, hives,
edema, inflammation, or severe diarrhea,
phlebitis at I.V. site; black tongue, sore
superinfection; throat, fever, or
hypersensitivity unusual bleeding
reactions including or bruising.
serum sickness and
anaphylaxis