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Pet Stuff Vet. Hospital Bucharest Report No.: 2304-Q-25892

PET STUFF UNIVERS Date of arrival: 05.04.2023
Str. Dezrobirii, Nr. 15 Date of report: 12.04.2023
060987 Bucuresti, Sector 6 Testing started: 05.04.2023
Rumänien Testing completed: 12.04.2023
Status of the report: Final report

Species: Dog
Breed: Mixed
Gender: Male
Name: 23858
Date of birth / Age: 01.06.2011
Type of sample: Tissue
Date sample was taken: 03.04.2023
Owner / Animal-ID: 11403001116
IT No. / Report-ID: 23858

Histological examination

Macroscopical findings:
Six samples ranging from 0.2 x 0.2 x 0.2 cm and 0.8 x 0.6 x 0.5 cm were received and processed.
All samples were examined histologically as is. Location provided in submission form: Footpad

Microscopic examination:
The following staining was performed according to standard operation procedures: H&E.
Skin. The epidermis is diffusely & irregularly thickened/ hyperplastic with numerous, rete ridges infiltrating into
the underlying dermis. Overlying the intact epidermis there is a thick layer of orthokeratotic hypereosinophilic,
compact and basket-weave hyperkeratosis.
Within the superficial dermis, within the interstitium, surrounding the vessels and infiltrating into the deeper
layers of the dermis, there are coalescing foci of inflammation characterized by mainly neutrophils as well as
fewer histiocytes, lymphocytes and plasma cells. The interstitium is moderately distended by increased amount
of collagen (fibrosis).
Within the dermis, there is a locally extensive area of granulation tissue. This is characterized by a proliferation
of fusiform, plump cells (fibroblasts) within an edematous stroma with collagen deposition and numerous,
variably sized, congested vessels perpendicularly oriented and lined by a plump, reactive endothelium. The
vessels are diffusely congested lined by a reactive endothelium. The lymphatics are diffusely and moderately
ectatic.

Diagnosis:
Skin. Dermatitis, suppurative, lymphohistiocytic, interstitial and perivascular, with fibrosis and granulation
tissue

Steubenstraße 4 · 97688 Bad Kissingen · Tel.: 09 71/ 7 20 20 · Fax: 09 71/ 6 85 46 · Geschäftsführender Gesellschafter: LABOKLIN Verwaltungs-GmbH · RG. Schweinfurt HRA 3631
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 Sample ID: 2304-Q-25892

Critical report:
A pododermatitis is a very heterogenetic disease, that can be induced by a multiplicity of causes. Besides
foreign bodies and trauma, a multitude of chemical and mechanical irritations as well as allergies are possible.
Parasitic, fungal and bacterial infections can occur. Psychogenic dermatitis due to licking is possible as well. In
many cases, the primary cause can not be detected and chronic, difficult to treat, bacterial infections develop.
The presence of neutrophils within the sections examined may suggest an infectious, most likely bacterial,
component. This could be either primary or secondary, thus complicating the clinical picture. The amount of
granulation tissue and fibrosis suggest a chronic-ongoing process.
In this case, performing further ancillary testing, such as bacterial culture may be beneficial to potentially isolate
a causative agent.

These results are based on the sample material submitted to our laboratory.

This was suitable if not stated otherwise. The submitter is responsible for the accuracy of the information regarding the sample. This report can only
be transmitted in toto and unchanged. Doing otherwise requires written permission from Laboklin GmbH & Co. KG.

LABOKLIN is an accredited laboratory according to DIN EN ISO/IEC 17025:2018, DAkkS No. D-PL-13186-01-01 and D-PL-13186-1-02.
The accreditation applies to all test procedures listed in the accreditation certificate.

TÄ Fr. Cerezo Echevarria

DVM DipACVP

*** END of report ***

Laboklin App
*** News from the laboratory ***
From now on, most clinical chemistry profiles will measure the degree of haemolysis and lipaemia of the
submitted sample and indicate, whether this affects any of the parameters and if so, which ones.

Steubenstraße 4 · 97688 Bad Kissingen · Tel.: 09 71/ 7 20 20 · Fax: 09 71/ 6 85 46 · Geschäftsführender Gesellschafter: LABOKLIN Verwaltungs-GmbH · RG. Schweinfurt HRA 3631
Bankverbindung: Sparkasse Bad Kissingen (BLZ 793 510 10) Kto.-Nr. 311 596 19, IBAN: DE09 793 510 1000 311 596 19, SWIFT/BIC: BYLADEM1KIS
BCEE Luxembourg Kto.-Nr.1507/3600-5,IBAN: LU95 0019 1507 3600 5000, SWIFT/BIC: BCEELULL
e-Mail: info@laboklin.com · USt.ID DE206897824
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