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2019

2019

IMPACT ON THE COST OF PRODUCTION AND ZOOTECHNICAL


PERFORMANCE OF BROILERS SUBMITTED TO TWO DIFFERENT VACCINATION PROGRAMS
A.J.Lima Neto¹, J.R Vogt¹, E.C Muniz¹, G.B.C Salles¹, R. J. P. Felício²
1
Zoetis Industry of Veterinary Products Ltd – São Paulo/Brazil | 2 Universidade Estadual do Ceará – Fortaleza

INTRODUCTION
Newcastle disease is among the main officially controlled diseases. Since
1997, there have been no reported outbreaks of the disease in commercial
establishments and vaccination is a fundamental tool for its prevention. By
removing part of the NDV F protein gene and inserting it into a genetically
modified HVT, the researchers created vectorized vaccines with protection
against Newcastle and Marek diseases. The aim of this study was to compare
production parameters, in addition to cost per ton live weight of two different
vaccination programs in an integration of broilers, located in the Northeast
of Brazil.

MATERIALS AND METHODS


Figure 2 – Box plot of performance data evaluated between the two treatments.
The program used in T01 consisted of the application of an antigen-antibody
complex vaccine (strain V877) against the infectious bursal disease, plus However, it is noted that T01 was numerically better in all parameters when
a vectorized vaccine for Newcastle and Marek’s diseases from the same compared to T02. As a result, statistically significant differences in the cost
laboratory. On the other hand, the birds in T02 received a triple vectorized were detected with p value of < 0.0001 between T01 and T02.
vaccine, with protection against the three diseases mentioned above, in
addition to a live attenuated vaccine against NDV, strain C2, applied via spray
also in the hatchery. The work took place from April to August 2022 and
included a total of 5,645,667 birds (T01- 2,580,720 birds; T02- 3,064,947 birds).

RESULTS AND DISCUSSION


The summary of the results by treatment is shown below:
The equivalence between T01 and T02 in results of age, ADG, FCR and IEP could be
achieved with margin of 10%. No equivalence between T01 and T02 in body
weight and final mortality could be concluded due to greater variability in
the data.
Figure 3 – Results of equivalence margin comparing T01 vs. T02.

CONCLUSION
Therefore, this difference gives us an indication of the best options to
compose future vaccine protocols in this integration, to achieve better
zootechnical indicators, such as those that were demonstrated, and,
consequently, return on investment.
REFERENCES
1. Dimitrov K, et al. Newcastle disease vaccines - A solved problem or a continuing challenge? Vet Microbiol 2017;206:126-136. 11
2. Luo Y, et al. Construction and e_ cacy of a recombinant HVT-ND vaccine against NDV and MDV challenges in SPF and NDV challenge in broiler birds. Am Associat Avian Pathol. 2019
3. Bosserd M, et al. Onset of immunity of a recombinant HVT-ND against a velogenic NDV challenge in SPF birds. Am Associat Avian Pathol. 2019.
4. SDA-MAPA. Plano Nacional de Prevenção da Influenza Aviária e de Controle e Prevenção da Doença de Newcastle, ANIMAL, S.D.A, 2006.
5. Jeurissen SHM, Janse EM, Lehrbach PR, Haddad EE, Avakian AP, Whitfill CE. The working mechanism of an immune complex vaccine that protects chickens against
infectious bursal disease. Immunology 1998; 95:494-500
6. Muniz EC, Verdi R, DiFabio J, Bordin EL. Estudo histopatológico e sorológico com vacina de imunocomplexo contra a doença de gumboro com cepa v877 em aves SPF. XV
Congresso da APA – Produção e Comercialização de Ovos Ribeirão Preto, SP 21 a 23 de março de 2017
Figure 1 -Least squares means (lsmeans) difference of two treatments with lower limits (LL) and upper limits (UL)
of 95% confidence interval (CI). Copyright Zoetis Indústria de Produtos Veterinários Ltda. Todos os direitos reservados. Material produzido junho/2023.

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