CASE Transmetatarsal Amputation

Fish-Skin Graft implanted to reinforce

soft tissues where weakness exists

Kerecis® Omega3

SurgiBind
TM

Intact fish-skin grafts

for tissue regeneration

Transmetatarsal amputation (TMA), is a surgical procedure where infected, necrotic, CASE BY:
ischemic tissues are resected while preserving as much of the forefoot. While this is a limb JONATHAN HOOK DPM
preservation procedure, it has a high complication rate. In a retrospective study of 101 CHICAGO, IL
TMAs by Pollard, et al, results showed that 87% had post-op complications and one
common complication is wound dehiscence at 51.5%1. SurgiBind is indicated for
reinforcement where soft tissue weakness exists. The implanted graft provides a scaffold
recruiting the body’s own cells to the implant and supports them to proliferate,
differentiate and synthesize new extracellular matrix.

Patient history
• 73 year old female
• History of DM, HTN, PVD and HLD

Wound history
• Presented with full thickness ulcer to the 4th interspace of the left foot due to blunt trauma (water bottle)
• Diagnosed with acute osteomyelitis 4th metatarsal and septic joint, wet gangrene, abscess

Treatment
• Initial treatment: Incision and drainage, antibiotics and partial resection of 3rd and 4th metatarsal
• Surgical pathology showed acute osteomyelitis at resection margins
• Transmetatarsal amputation was performed

Outcome
• Wound healed with no complications post surgery

FSG OVER SOFT TISSUES DAY 3 DAY 42

AND BONES APPLIED INTRA-OP POST OP, NPWT D/C WOUND CLOSED

Reference:
1. Pollard J, Hamilton GA, Rush SM,
Ford LA. Mortality and morbidity after
transmetatarsal amputation: retrospective
review of 101 cases. J Foot Ankle Surg.
2006; 45(2):91-97.
 Composition Fish skin from north Atlantic cod
Pore size Intact three-dimensional skin structure
Appearance Flat, dry sheet with scale-textured surface and smooth underside
Solid or pre fenestrated
Storage Shelf stable for three years at room temperature
Rehydration Hydrate at least 60 seconds in room temperature sterile saline
Intraoperative handling Can be trimmed to size wet or dry. Place with textured side facing up
or towards distal aspect.
Lay graft flat in surgical plane, avoiding buckling of tissue or tenting.
Secure with sutures.
Sterilization Via exposure to ethylene oxide gas. Sterility assurance level (SAL) 10-6 with undetectable
ethylene oxide residuals.
Regulatory FDA 510(k) approved medical device indicated for soft tissue reinforcement. Not subject to
FDA Guidance on human cells, tissues, and cellular and tissue-based products (HCT/Ps).

Catalog # Catalog # Size Size

Description
Box of 10 Single Unit Dimensions Area cm2
SOLID
50241S02D2D 50241S02D0D Kerecis Omega3 SurgiBind 3 x 7 cm 21 cm2
50241S10D2D 50241S10D0D Kerecis Omega3 SurgiBind 3 x 12 cm 36 cm2
50241S03D2D 50241S03D0D Kerecis Omega3 SurgiBind 7 x 10 cm 70 cm2
50241S21D2D 50241S21D0D Kerecis Omega3 SurgiBind 7 x 20 cm 140 cm2
50241S24D2D 50241S24D0D Kerecis Omega3 SurgiBind 250 cm2 250 cm2
FENESTRATED 1:1
50241G02D2D 50241G02D0D Kerecis Omega3 SurgiBind Fenestrated 1:1 3 x 7 cm 21 cm2
50241G10D2D 50241G10D0D Kerecis Omega3 SurgiBind Fenestrated 1:1 3 x 12 cm 36 cm2
50241G03D2D 50241G03D0D Kerecis Omega3 SurgiBind Fenestrated 1:1 7 x 10 cm 70 cm2
50241G21D2D 50241G21D0D Kerecis Omega3 SurgiBind Fenestrated 1:1 7 x 20 cm 140 cm2
50241G24D2D 50241G24D0D Kerecis Omega3 SurgiBind Fenestrated 1:1 250 cm2 250 cm2

OUR VISION FDA approved, U.S. and international KERECIS

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in tissue ­regeneration by pending.
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sustainably harnessing
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nature’s own remedies
Phone: (703) 287-8752
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Email: info@kerecis.com

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