Professional Documents
Culture Documents
1. It refers to the responsible provision of drug therapy to 2. Any noxious, unintended, and undesired effect of
achieve definite outcomes that are intended to improve a a drug that occurs at doses used in humans for
patient’s quality of life: prophylaxis, diagnosis or therapy:
a) Drug therapy assessment a) Allergy
b) Therapeutic drug monitoring b) Adverse drug reaction
c) Pharmaceutical care c) Adverse drug event
d) Professional-patient relationship d) Hypersensitivity
e) Idiosyncrasy
CORRECT ANSWER:D
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CORRECT ANSWER:C
d) NOTA 2. Education
3. Research
4. Public Health
CORRECT ANSWER:D
6. The most serious drug-induced blood disorder: 7. A way of summarizing the health benefits and
resources used by competing health care programs so
a) Aplastic anemia
that policy makers can choose among them:
b) Leukemia
a) Cost-of-Illness Evaluation
c) Agranulocytosis
b) Cost-Minimization Analysis
d) Thrombocytopenia
c) Cost-Utility Analysis
d) Cost-Effectiveness Analysis
e) Cost-Benefit Analysis
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CORRECT ANSWER:C
b) Establish program for safe and efficient drug usage • Chair: Medical Director
c) Develop a formulary of drug • Secretary: Chief Pharmacist
d) AOTA
• FUNCTIONS OF PTC
e) NOTA 1. Develop Formulary and operate formulary
2. Policy development and governance of
medication use process
3. Perform drug medication use evaluation
4. Monitor ADRs and Medication Error
CORRECT ANSWER:E
10.Potential adverse effects of Aspirin include: 11.Which of the chemotherapeutic agents is most likely
I. GI ulceration associated with pulmonary toxicity?
II. Hypersensitivity asthma a) Vincristine
III. Cardiac arrhythmias b) Doxurubicin
a) I only
c) Paclitaxel
b) II only
c) I and II d) Bleomycin
d) II and III
e) I, II, and III
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13.Early sign of epinephrine decomposition is: 14.A private or public organization that provides
comprehensive healthcare services to individuals
a) Pink discoloration
enrolled to the organization:
b) Red precipitate
a) Hospital
c) Turbid discoloration
b) Health Management Organization
d) Black precipitate
c) Health Maintenance Organization
15.A type of drug distribution system that makes Drug Distribution Systems
medication available at nursing units of hospitals and for
which a charge is made to the patient. • Used most often in governmental & other
Floor-Stock hospitals in which charges are not made to the
a) Charged Floor Stock System patient or when all inclusive rate is used for
charging
b) Free Floor Stock
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16. A patient who overdosed on neostigmine is expected 17.MAO Inhibitors + Tyramine Rich Food
to manifest with the following signs or symptoms except:
a) Headache and Vomiting
a) Diarrhea
b) Increase in BP
b) Bronchoconstriction
c) Cancer
c) Mydriasis
d) Increase risk in hypoglycaemia
d) Bradycardia
e) Lacrimation
18.A drug induced hypersensitivity reaction caused by 19.Type F ADR can occur as a result of the following
sulphonamides except:
a) Parkinson Disease a) AMR
20.Vital signs
I. Pulse Rate
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21. Silver and sodium chloride, when mixed, can lead to 22. Acacia and Fe salts, when mixed, can lead to this
this incompatibility: incompatibility:
a) Eutexia c) Precipitation a) Evolution of gas c) Cementation
23 When barbiturates is taken together with another 24. Interaction of aminoglycosides and loop diuretics
drug, this will likely result to: may result to:
a) Increased effect of the other drug a) Ototoxicity
25. Alcohol and antihistamines, when taken together, 26. Nonselective Beta-blockers are recommended for
may result to: asthmatic patients with hypertension. Cromolyn sodium
is an example of a mast cell stabilizer.
a) Increased metabolism
a) First statement is TRUE, second statement is FALSE.
b) Decresed metabolism
b) Second statement is TRUE, first statement is FALSE
c) Increased sedation
c) BOTH statements are TRUE
d) Decreased antihistamine effect
d) BOTH statements are FALSE.
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CORRECT ANSWER:C
• 28. It reversibly inhibits various enzymes present in the Drugs for Diabetes
brush-border of the mucosa of small intestines which are
responsible for the breakdown of complex carbohydrates
into monosaccharides: Classes Example
Meglitinides Nateglinide, Repaglinide
a) Insulin
Biguanide Metformin
b) Acarbose Alpha glucosidase Acarbose, Voglibose and Miglitol
inhibitor
c) Chlorpropamide
Thiazolidinediones Pioglitazone, Rosiglitazone
d) Glipizide Amylin Analogue Pramlinitide
GLP- 1 Agonist Exenatide, Liraglutide
DPP IV Inhibitor Sitagliptin, Liragliptin
CORRECT ANSWER:B
29. The medication requires ondansetron which is main 30. It is a rapid-acting insulin preparation that has a 4-5
indicated for the treatment of: hours duration of action.
a) Depression a) Insulin glargine
b) Schizophrenia b) NPH
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Drugs for Diabetes 31. The classical sign of diabetes mellitus includes the ff:
polydipsia, polyuria, ketonuria, rapid weight loss, and a
Classes Example random plasma glucose levels of:
Insulin Short Acting: Lispro, Aspart, Glulisine
a) 100 mg/dL
Regular Insulin- ROA: IV b) 200 mg/dL and up
Intermediate Acting: NPH Insulin, Protamine c) 150 mg/dL
Lispro, Protamine Aspart
d) 160 mg/dL
Long Acting: Glargine, Detemir, Insulin Zinc
Suspension
CORRECT ANSWER:B
32. It is the hypermetabolic syndrome that occurs from 33. Adverse effects of metoclopramide limit its
excessive production of thyroid hormone with classic usefulness. These adverse effects include:
symptoms of weight loss, nervousness, palpitation, heat
intolerance and insomnia:
I. Insomnia
a) Hypothyroidism
II. Depression
b) Hyperthyroidism
III. Extrapyramidal effects
c) Both A and B
a) II and III b) I and II c) I and III d) I, II, III
d) None of the above
CORRECT ANSWER:A
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CORRECT ANSWER:D
d) Glycerin
38. A paracetamol tablet contains 1 1/5 grains. How 39. In psychosis, there is primarily:
many grams of paracetamol are needed to make 1000
tablets? a)Increased dopaminergic activity
b) 78 g c)Both A and B
d) 70 g
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40.How many mg of isofluorophate are contained in 20 g 41. The following are manifestations of chemical
of a 1: 10,000 ophthalmic solution of isofluorophate in instabilities, except:
peanut oil?
a) Evolution of gas
a) 4.2 g
b) Immiscibility
b) 1.9 g
c) Color change
c) 2.0 g
d) Gel formation
d) 3.0 g
42. Which of the following is not an outcome included in 43. These are propanolol’s indications, except:
the definition of pharmaceutical care:
a) Migraine
a) Cure of the disease
b) Stage fright
b) Elimination or reduction of symptoms
c) Hypertension
c) Slowing of disease processes
d) None of the above
d) Reducing healthcare costs
CORRECT ANSWER:B
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Synergism Potentiation
Drugs Effects
Drugs Effects
Amoxicillin Clavulanic Acid Increased amoxicillin’s antibiotic effect
Trimethoprim Sulfamethoxazole Bactericidal
Ampicillin Sulbactam Increased ampicillin’s antibiotic effect
Chemical
• Protamine sulfate + Heparin b) 500 mg tablet
• Sodium sulfate + Barium chloride
c) As needed
• Acetylcholine (dec HR) + Epinephrine (inc
Functional HR)
d) M. ft. sol
• Papaverine (vasodilation) +
Non-competitive Norepinephrine (vasoconstriction)
CORRECT ANSWER:D
CORRECT ANSWER:C
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47. The following statements about lactulose are true: 48. A condition characterized by a poorly functioning
I. It is an osmotic laxative colon and resembles ulcerative colitis due to chronic use
II. It can cause flatulence and cramps of stimulant laxatives:
III. It is used as a sweetening agent
IV. It is taken with juice or milk to increase palatability a) Melanosis coli
49. Which of the following products is an iron 50. One advice the pharmacist may explain upon
preparation: dispensing ferrous sulfate supplement is that it may
I. Iberet II. Circulan III. Feldene discolor the stool _______.
a) I a) Orange
b) II b) Brown
c) I, II c) Black
d) I, II, III d) Green
51. Iron supplement given to pregnant women 52. Side effect of selective beta blockers
a) Ferrous sulfate a) Hypotension
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53. Main site of biotransformation 54. Beta blocker also used for migraine and stage fright
a) Lungs a) Propranolol
b) Liver b) Labetalol
d) Kidneys d) Betaxolol
55. Relief of pain without altering consciousness 56. Which of the following is not advertised?
a) Analgesia a) Mefenamic acid 500mg
57. The only insulin that can be administered by IV bolus, 58. Common names of Cannabis, except
IV infusion, or IM injection:
a) MJ
a) Regular insulin
b) Weed
b) Humalog
c) Hashish
c) Apidra
d) Green amore
d) Lantus
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59. Blocks the action of the Parasympathetic Nervous 60. Diphenoxylate atropine was the old generic name of
System
a) Lomotil
a) Sympathomimetics
b) Diphenoxylate Atropine
b) Symphatetic NS
c) Loperamide Atropine
c) Parasympatholytics
d) Diphenoxylate
d) Parasympathetic NS
CORRECT ANSWER:C
CORRECT ANSWER:A
61. Functions of the PTC: 62. Disadvantage/s of the individual prescription order
I. Develop Formulary and operate formulary system of drug distribution:
II. Policy development and governance of medication use I. increased potential for medication errors
process II. increased drug inventory
III. Perform drug medication use evaluation III. delay in drug administration
IV. Monitor ADRs and Medication Error a) I and II c) III only e)II and III
a) I and II b)I, II, III c)II, III, IV b) I only d) I and III
d)I, II, III, IV
c) Bronchodilation c) Nitrates
d) Hemorrhage d) None
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65. Dose order: Drug A 15mEq po everyday Available: 66. If Drug A is a potent inhibitor of cytochrome oxidase.
Drug A 10mEq/5mL What would likely happen to Drug B if it is metabolized
How many mL of Drug A will you give? by the same enzyme?
a) 0.133mL a) Increase metabolism
b) 3.33mL b) Increase clearance
c) 7.5mL c) Increase potency
d) 10.5mL d) Increase effect
67. Which of the following is the proper mixing of 68. The most common side effect of erythromycin
dextrose, fatty acids, and amino acids? therapy is:
a) fatty acids + dextrose then amino acids a) Hysterical laughing
69. Which of the following drugs is administered solely 70. Physiological antidotes for narcotics:
by inhalation?
a) Atropine
a) Beclomethasone dipropionate
b) Ephedrine
b) Epinephrine HCl
c) Naloxone
c) Dexamethasone
d) Codeine
d) None of the above
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71. How many milliliters of resorcinol monoacetate 72. How many milliequivalent are there in 15000 (should
should be used to prepare 1 pint of 15% (v/v) lotion? be 150mL) ml of a 50% W/V MgSO4 solution?
a) 65ml a) 62.5 mEq
73. What is the molarity of a solution that is prepared by 74. The anticoagulant action of heparin is quantified by
dissolving 10g of KCl (MW=74.50) in enough water to using the
make 500ml of solution?
a) complete blood count
a) 0.168M
b) activated partial thromboplastin time (APTT)
b) 0.258M
c) prothrombin time (PT)
c) 0.268M
d) International Normalization Ratio (INR)
d) 0.3000M
75. A 20-year-old asthmatic patient has been treated with 76. A 250-mL infusion bottle contains 5.86 g of
zileuton (Zyflo) 600 mg QID. While the patient seems to
tolerate the drug well, she has brief episodes of potassium chloride (KCl). How many milliequivalents
bronchospasm several times a week. Which of the following (mEq) of KCl are present?
drugs would NOT be appropriate to recommend for the
treatment of acute bronchospasm in this patient? a) 12.7mEq
I. zafirlukast (Accolate)
II. triamcinolone acetonide (Azmacort) b) 20 mEq
III. salmeterol (Serevent)
a)II and III only c) III only c) 78.5 mEq
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77. How many mg of sodium chloride are needed to adjust 30 78. The USP states that 1 g of a chemical is soluble in 10 mL
mL of a 4% cocaine HCl solution to isotonicity. The freezing of alcohol. What is the percentage strength of a saturated
point depression of a 1% solution of cocaine Hel is.09 solution of this chemical if alcohol has a sp. gr. of 0.80?
degrees.
a) 10.0% W/V
a) 62
b) 83 b) 10.0% W/W
c) 108 c) 11.1%W/V
d) 120 d) 11.1%W/W
79. Dopamine (Intropin) 200 mg in 500 mL of normal 80. Insulin therapy is indicated in all of the following except:
saline at 5 ug/kg/min is ordered for a 155-lb patient.
a) Newly diagnosed type 1 DM
What is the final concentration of solution in ug/mL?
b) Gestational diabetes mellitus (GDM) not controlled by
a) 0.4 g/Ml
diet
b) 2.5 ug/mL
c) Newly diagnosed type 2 DM
c) 40 ug/mL d) Hyperglycemic hyperosmolar nonketotic syndrome
d) 400 ug/mL (HHNS)
81. Caffeine + aspirin 82. A visual display technique that can be used as a
scheduling tool of the entire planning process
a) caffeine increases the bioavailability of aspirin
a) Curve fitting
b) caffeine increases the rate of absorption of aspirin b) Gant chart
e) Distribution
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83. How do you classify a drug interaction that is very 84. Which of the following NSAIDs appears to interact
likely but might not be proven clinically? least significantly with Captopril, an ACE inhibitor?
a) established a) indomethacin
b) probable b) ibuprofen
c) suspected c) aspirin
d) possible d) sulindac
85. Two drugs are said to be ____ if the drugs do not 86. How many mL of water is needed to make 2 g of
cause responses of the same quality. Atropine Sulfate isotonic? Atropine Sulfate has an E-
value of 0.12.
a) homergic
a) 4 mL
b) homodynamic
b) 13.33 mL
c) heterergic
c) 24 mL
d) summative
d) 26.67 mL
87. What is the amount of NaCl (in grams) needed to 88. How many millimoles are there in 2.40 grams of
make the CaCl2?
following solution isotonic? 1% Ephedrine HCl and 1%
NaCl has freezing point depressions of 0.169 and 0.58, a) 21.62 mmol
respectively.
Ephedrine HCl 0.35 g b) 31.79 mmol
Sodium Chloride q.s.
c) 43.24 mmol
Purified Water q.s. ad 70 mL
a)0.42 g b)0.64 g c)0.53 g d) 266.4 mmol
d)0.35 g
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89. How many mEq of KCl are there in 50 ml of a 3% KCl 90. How much water (in mL) must be added to three
solution? tablespoons of 1:250 w/v peppermint spirit if it is to be
diluted to 0.05% w/v?
a) 40.27 mEq
a) 360 mL
b) 20.13 mEq
b) 5.63 mL
c) 111750 mEq
c) 5.23 mL
d) 223.5 mEq
d) 315 mL
91. A pharmacist combines the contents of a 30-g tube of a 92. Express Absolute Zero temperature in Fahrenheit.
0.5% ointment and a 90-g tube of a 1.5% ointment of the
same active ingredient. What is the concentration of the a) – 0 °F
mixture?
a) 1% b) – 459.67 °F
b) 0.75% c) – 273.15 °F
c) 1.25% d) – 373.15 °F
d) 0.9%
93. In what proportion should 5% and 1% hydrocortisone 94. How much tax must one pay if one is purchasing 15
ointments be mixed to prepare a 2.5% ointment? wine gallons of 35% alcohol? Tax levied is Php
a) 1.5 parts of 5% and 2.5 of parts 1% hydrocortisone 20.00/proof gallon.
ointment a) Php 210.00
b) 3 parts of 5% and 5 parts of 1% hydrocortisone
ointment b) Php 300.00
c) Both A and B c) Php 105.00
d) Neither A nor B
d) Php 420.00
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95. What is the VAT imposed on an NSS bag with a final 96. How much is the total cost of 20 Fluimucil® effervescent
selling price of Php 105.00? tablets? The base price per tablet is Php 15.00. The
pharmacist also adds a 35% mark-up to increase revenue.
a) Php 12.60
a) Php 105.00
b) Php 18.22
b) Php 405.00
c) Php 14.52
c) Php 300.00
d) Php 11.25 d) Php 335.00
97. How much is the final price of a 250-mL bottle of 98. A medication order calls for 1000 mL of dextrose
rubbing alcohol originally priced Php 50.00 after a intravenous infusion to be administered over an 8-hour
customer availed a 15% Christmas discount, a 10% early period. Using an intravenous administration set that delivers
bird discount, and a 5% hidden discount all on the same 10 drops/mL, how many drops per minute should be
product? delivered to the patient?
99. Ten mL of 10% calcium gluconate injection and 10 mL of 100. Treatment A costs Php 17,500.00 and extends the
multivitamin infusion are mixed with 500 mL of a 5%
dextrose injection. The infusion is to be administered over 5 patient’s life by 3 years with a Utility Value of 0.4 while
hours. If the dropper in the venoclysis set calibrates 15 Treatment B costs Php 19,000.00 and extends the
drops/mL, at what ratem in drops per minute, should the patient’s life by 2 years with a Utility Value of 0.8. Which
flow be adjusted to administer the infusion over the desired
time interval? is the better option?
a) 26 drops per minute a) Treatment A
b) 17 drops per minute b) Treatment B
c) 14 drops per minute
c) Both are equally beneficial
d) 25 drops per minute
d) Not enough information is given
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