Professional Documents
Culture Documents
• Laboratory investigations:
• Imaging: CXR, CT, Ultrasonography, MRI, PET-CT, V/Q
• PFT
• Bronchoscopy
• Thoracoscopy
• mediastinoscopy
Laboratory medicine
Laboratory medicine involves the study of patient tissue and fluid
specimens and consists of five disciplines.
• Platelets
• Prothrombin
time
• prothrombin
concentration
• INR
• D. Dimer
Infection Monitoring
• Procalcitonin (PCT): In healthy individuals PCT levels are
less than 0.1 ng/ml. A diagnosis of sepsis is confirmed
when PCT levels are greater than 0.5 ng/ml and excluded
when PCT levels are 0.2 ng/ml or less.8
• Microbiology tests
• Sputum Gram Stain
• Sputum Culture
• Acid-Fast Testing
• Gram stain and culture from any specimens
If the Gram stain shows few (<25 per low-power
field) or no pus cells and numerous epithelial cells,
and the sample must be discarded = SALIVA.
A sample with numerous pus cells and few epithelial
cells is most likely a true lung sample and likely
reflects the infection source.
Sweat chloride test
• Patients with cystic fibrosis have increased levels of Cl− in their sweat
because of an inability to reabsorb it.
• These patients typically have sweat Cl− levels greater than 60 mmol/L,
whereas values of 40 to 60 mmol/L are considered borderline for cystic
fibrosis.
• Sweat Cl− levels less than 40 mmol/L are considered unlikely to confirm
the diagnosis.