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DEPARTMENT OF HORMONES
Notes:
*Reference values as per textbook is based on age-related physiologic changes in normal people without evident thyroid diseases.Treatment for
hypo/hyperthyroidism is purely based on supportive TSH levels, clinical findings or fT3 or fT4 levels.Manufacturer's reference interval is considered as
the target TSH levels for most (not all) of the individuals on thyroid disease treatment.So clinical interpretation by a professional is always advocated.
Based on the thyroid hormones and TSH levels it can be classified as subclinical,primary or central.Apart from this,certain other conditions can also
leads to diagnostic confusions in the interpretation of a Thyroid function test (Especially if TSH alone is considered), they are Pregnancy, Levo-thyroxine
therapy (Eg recent/non-adherence to therapy etc), certain other drug therapy,assay interference,iodine deficiency, alterations in thyroid hormone binding
protein's concentration and its binding capacity,Non-thyroidal illness, Genetic conditions,Assay interference,Central hypothyroidism, TSH-secreting
pituitary adenoma, Resistance to Thyroid hormone,and Disorders of thyroid hormone transport or metabolism etc. TSH secretion exhibits a diurinal
pattern , so its advisable to check it during morning.TSH receptor present in Thyroid gland can be stimulated or inhibited by auto-antibodies produced in
autoimmune thyroid disorders, which can lead to functional abnormalities of thyroid gland.The samples of TSH will be preserved in the lab only for 2
days after performing the test.Hence for any queries regarding the reports,kindly inform within this time period.
Cholecalciferol (Vit D3) and Ergocalciferol (Vit D2) are the two types of Vitamin D which our body can use for its needs. Sources of Vit D:- Diet (Vit D3 &
Vit D2).Sun-light stimulated skin cholesterol mediated synthesis (Vit D3).Taking dietary factor into consideration its preferable to take Vit D samples in a
fasting status.
Other diseases/disorders associated with Vit D levels :- Rickets, Osteomalacia, Allergy,Asthma, Psoriasis etc.
Total 25-hydroxy Vit D values can also be affected by certain factors like Diet, Latitude, Sun-exposure, Season, Age, Skin pigmentation and Sun-screen
use, Malabsorption ,Breast feeding, Gastric/small bowel resection, Drugs (Including Vit D),Liver diseses and Kidney diseases.
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DDRC SRL DIAGNOSTICS PRIVATE LIMITED
Araninnavila Building, Opp. IDBI Bank,
Kottappuram, Paravoor P.O., Kollam - 691301.
Mail: paravoor@ddrcsrl.com Phone : 9496005207
CIN:U85190MH2006PTC161480
DEPARTMENT OF HORMONES
SHINI S
LAB TECHNICIAN
Dept of Hormones
KOLLAM Tel:-7356607964
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