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1. When a person has to take 3 bottles of beer to fall asleep instead of the usual
one bottle, this individual is manifesting-
A. addiction
B.dependen
ce
C.tolerance
D.toxicity
2. Which drug increases dopamine by binding to G protein coupled receptors in
the GABA inhibitory interneurons in the VTA?
A. ecstasy
B. inhalant
C. morphine
D. diazepam
3. A street drug user is brought into the ER unconscious. The individual is
bradycardic and has a respiratory rate of 9-10/minute. The pupils are pinpoint
and there are multiple needle marks on both arms. What should be given to
immediately reverse the condition?
A. flumazenil
B. naloxone
C. methane
D.bupropion

4. A housewife is unhappy about her marriage and manifests with anxiety and
sleep disturbances. She is prescribed with an anxiolytic sedative hypnotic which
she takes for several weeks. When her supply rans out, she is unable to obtain
a new prescription and subsequently manifests with irritability, insomnia, phono-
and photophobia. The MOST likely drug she is using is-
A. alprazolam
B. GHB
C. morphine
D. methadone
5. A chronic alcoholic develops a headache and takes paracetamol. The pain is
not relieved. The most probable reason is-
A. paracetamol is rapidly metabolized by CYP450
B. absorption of the pain reliever is delayed by alcohol
C. excretion of paracetamol is hastened due to diuresis from alcohol
D. nociceptive receptors are downregulated by ethanol

This material is downloaded for Richmond A. Amurao (20200015401)

at FEU Dr. Nicanor Reyes Medical Foundation.
For personal use only. No other uses without permission. All rights reserved.
6. A diabetic engages on a drinking spree and goes into a hypoglycemic coma
and lactic acidosis. This is due to elevation of what substance?
A. aldehyde
B. glucagon
C. NADH
D. insulin
7. A 14 year old sniffs from a plastic bag filled with a substance he stole from a
nearby hardware. He subsequently develops nasal mucosal ulcers and nose
bleeds.The MOST likely agent is-
A. rugby inhalant C. nicotine
B. marijuana D. cocaine powder
8. A person uses a highly addictive amphetamine- based stimulant. Mental
status changes, autonomic hyperactivity, hyperthermia, and neuromuscular
abnormalities eventually develops as a consequence of high levels of
serotonin.This syndrome is most likely cause by addiction to-
A.MDMA
C.cocaine
B.alcohol
D.heroin
9. An MDMA user runs out of money to buy the drug and misses the daily dose.
Which symptom will MOST likely manifest?
A. phonophobia C. nausea and vomiting
B. sedation D. depression
10. A person suffers depression and develops a smoking habit. Which of the
following will the BEST agent to address his addiction?
A. disulfiram
B. bupropion
C. nicotine gum
D. acamprosate

This material is downloaded for Richmond A. Amurao (20200015401)

at FEU Dr. Nicanor Reyes Medical Foundation.
For personal use only. No other uses without permission. All rights reserved.