Q)1. Most important cause of
After a mastectomy with
hyperaldosteronism is ?
a) Hyperglycemia
b) Hypertension
c) Cushing syndrome
d) addison disease
e) Adrenogenital syndrome T
Q) 2. A 35 year female is coming to the
clinical attention with moon face, buffalo
hump (deposition of fat back of neck and
back) due to cushing syndrome. It is due
to increase production of following
hormone ?
a) Growth hormone
b) Lactrotroph hormone
c) Gonodotroph hormone
d) Thyroid stimulating hormone
e) Adenocorticotrophic T
Q) 3. A 30-year-old school teacher is
know to beat a strict disciplinarian in the
class room. She has angina pectoris 6
months' duration. On physical
examination, her blood pressure is
135/85 mmHg. She is 168 cm (5 ft 5 inch)
tall and weight 82 kg. Coronary
angiography shows 75% narrowing of
anterior descending branch of the left
coronary artery. Angioplasty with stent
placement is performed. Which of the
following is the major risk factor
associated with these findings ?
a) obesity T
b) Type A personality
c) Diabetes mellitus
d) Sedentary life style
e) Age
Q) 4.
axillary node dissection for breast cancer
1 year ago, a 47-year-old woman has
developed persistent swelling and
puffiness in the left arm. Physical
examination shows firm skin over the left
arm and doughty underlying soft tissue.
The arm is not painful and discolored. She
developed cellulitis in the left arm 3
months ago. Which of the followings
terms best describes these findings ?
a) Thrombophlebitis
b) Subclavian arterial thrombosis
c) Tumor embolization
d) Lymphedema T
e) Vasculitis
Q) 5. Acute intratumoralhemorrhage a
sudden hemorrhage which occur in
pituitary edema is said to be ?
a) Posterior pituitary crisis
b) Somatotroph pituitary adenoma
c) Lactotroph pituitary adenoma
d) Pituitary apoplexy T
e) ACTH pituitary adenoma
Q) 6. A 25 years male has tall arms and
legs. He is suffering from increase level of
hormone from chilhood. What will be the
diagnosis ?
a) Acromegaly
b) Gigantism T
c) addison disease
d) Cushing's disease
e) Dwarfism
Q) 7. Insulin hormone causes peripheral Q) 11. Which of the following feature is
uptake of glucose and glycogen. Insulin true for paget's disease of breast ?
hormone is released from ?
a) Common manifestaion breast cancer
a) Alpha cells b) Palpable mass is present in all cases
b) Pancreatic polypeptide cells c) Paget cell cannot be detected from
c) beta cells T nipple secretion
d) D1 cells d) Clinicaly present as erythmatous
e) Enterochromaffin cells eruption of nipple skin T
e) Underlying carcinoma is usually well
Q) 8. Most common cause of differentiated
Hemorrhagic NIPPLE discharge is ?
Q) 12. In lactating mother most common
a) Galactocele cause of painfull BREAST lump is ?
b) Invasive duct cell carcinoma
c) Intraductal papilloma T a) Periductal mastitis
d) Breast Abscess b) Fibroadenoma
e) Granulomatous mastitis c) Acute mastitis T
d) Mammary duct ectasia
Q) 9. Which of the following genetic e) Fat necrosis
mutations are important in BREAST
cancer ? Q) 13. Sexually transmitted viral lesion of
cervix include ?
a) Pten
b) RB gene a) Endocervical polyp
c) BRCA1 T b) Squamous cell carcinoma T
d) BCL-2 c) Chronic cervicitis
e) P53 d) Leiomyoma
e) All of above
Q) 10. All of the following are histological
type of BREAST cancer ? Q) 14. Most common tumor arising from
ovarian surface epithelium ?
a) Scirrhous carcinoma T
b) Colloid carcinoma a) Serous T
c) Medullary carcinoma b) Mucinous
d) Metaplastic carcinoma c) Endometrial
e) Phyllodestumor d) Clear cell carcinoma
e) Brener
Q) 15. Which of following is most Q) 19. 60 years female complains of
common complication of heart failure ? postmenopausal bleeding, most common
cause is ?
a) Hydrothorax T
b) Pneumothorax a) Cervical carcinoma
c) Pyothorax b) Endometrial carcinoma T
d) Hemothorax c) Granulosa cell tumor ovary
e) Chylothorax d) An ovulatory cycles
e) Mild cystic hyperplasia endometrium
Q) 16. The Jones major criteria for
diagnosing rheumatic fever include all of
the following except ? Q) 20. 30 years female complains of sever
Colicky Abdominal pain and
a) Carditis Dysmenorrea, most common cause ?
b) Aortitis T
c) Polyarthritis a) Leiomyoma
d) Chorea b) Endometriosis T
e) Erythema marginatum c) Pelvic inflammatory disease
d) An ovulatory cycle
Q) 17. The most common cause of e) Endometrial hyperplasia
abdominal aortic aneurysm is ?
Q) 21. Most common malignant Surface
a) Trauma epithelial tumor of ovary is ?
b) Syphilis
c) Atherosclerosis T a) Brannertumor
d) Vasculitieds b) Serous cyst adenofibroma
e) Hypertension c) Serous cyst adenocarcinoma T
d) Clear cell Tumor
Q) 18. Most common benign germ cell e) Endometroid carcinoma
tumor of ovary is ?
Q) 22. In 4 years female child present
a) Mature cystic teratoma T with polypoid Mass projecting through
b) strumaovari VAGINA, Morphologically look as Bunch
c) Terato carcinoma of grapes ?
d) yolk sac tumor
e) Dysgerminoma a) Neuroblastoma
b) Embryonal Rhabdomyosarcoma T
c) Squamous cell carcinoma
d) Candylomaaccuminatum
e) Valvarinteraepithelial neoplasm
Q) 23. The risk of testicular tumor is Q) 28. The lymph nodes are 1st affected
higher in patients with ? by carcinoma of prostate is most likely ?

a) syphilitic orchitis a) Perivesical

b) Tuberculosis syndrome b) Iliac
c) Testicular ferminization T c) Inguinal
d) Non specific orchitis d) Obturator T
e) Testicular atrophy e) Sacral

Q) 24. Benign prostatic hyperplasia Q) 29. Which of the following special

originates in the ? types of Cystitis most likely related to
Diabetes mellitus ?
a) Transitional zone of prostate T
b) peripherals zone of prostate a) Ulcerative interstitial cystitis
c) Central zone of prostate b) Emphysematous cystitis T
d) Peri urethral zone of prostate c) Cystitis cystica
e) Capsule of the prostate d) Polypoid cystitis
e) Malkoplakia
Q) 25. Primary PeriCarditis is caused by ?
Q) 30. Most common site of formation of
a) Cossackie A virus T stone in urinary tract is ?
b) Influenza virus
c) Enterovirus a) Kidney T
d) Poliomyelitis b) Ureter
e) Mumps c) Urinary bladder
d) Urethra
Q) 26. The pathology of minimal change e) none of above
disease is ?
Q) 31. Renal cell carcinoma is called
a) Only inflammatory cell infiltration hypernephroma because ?
b) only lipid cell accumulation
c) Only loss of foot processes T a) It arises in upper pole of kidney T
d) Only messangialedema b) It arises in lower pole of kidney
e) Only membranous thickening c) It arises from adrenals
d) Tumor cells resemble clear cells of
Q) 27. Which of the following is most adrenal cortex
likely cardiac consequence of e) All of above
hyperthyroidism ?

a) Subendothelial necrosis
b) Coronary spasm
c) Arteroseptal infarct
d) Tachycardia T
e) Endocarditis
Q) 32. Paraneoplastic syndrome caused
by secretion of ACTH and VIP is seen in ?
a) Follicular adenoma
b) Medullary adenoma T
c) Papillary carcinoma
d) Follicular carcinoma
e) Anaplastic carcinoma
Q) 33. Granulomatous thyroiditis is
triggered by ?
a) Parasitic infection
b) Bacterial infection
c) Fungal infection
d) Viral infection T
e) Auto-immunity
Q) 34. Maternal graves disease leads to
neonatal ?
a) Hypothyroidism
b) Hyperthyroidism T
c) Depends on duration of pregnancy
d) Depends upon degree of
hyperthyrodism
e) Euthryroidism
Q) 35. The leading cause of mortality in
ischaemic heart disease is sudden death
which is due to ?
a) Atrial fibrillation
b) Ventricular fibrillation T
c) Myocardial ischaemia
d) Hypotension
e) Coagulation necrosis
Q) 36. During a routine pelvic
examination, a 25 year old female was
found to have enlarged uterus.
Ultrasound report showed a
multiloculated cystic structure in the
uterine cavity. The mass was removed by
a dilation &curretage (D & C) of the
uterus and it showed placental like
tissue. Which tumor marker is helpful in
diagnosis and prognosis?
a) CEA
b) PSA
c) S-100
d) Beta-HCG T
e) CA-125
Q) 37. Which of the following is the most
common form of vasculitis in adults ?
a) Temporal arteritis T
b) Kawasaki disease
c) Wegener granulomatosis
d) Churgstrauss syndrome
e) Takayasu arteritis
Q) 38. Restricted cardiomyopathy most
likely occurs in ?
a) Hemochromatosis
b) Amyloidosis T
c) Sarcoidosis
d) Tuberculosis
e) Chronic anaemia
Q) 39. Which of the following is not
principle component of atherosclerotic
plaque ?
a) Smooth muscle cells
b) Macrophages
c) Neovascularization
d) Calcium
e) Magnesium T
Q) 40. A 70 years old man presented with
left vetricular failure and a harsh systolic
murmur. Echocardiography revealed
stenosis of aortic valve as well as
hypertrophy and dilation of the left
ventricle. Which change would also be
expected ?
a) Dilation of ascending aorta
b) Dissection of ascending aorta
c) Calcification of aortic valve T
d) Rapture of aortic valve
e) Vegetation on the aortic valve
Q) 41. Frequent site of tuberculosis in
female genital system is ?
a) Cervix
b) Vagina
c) Endometrium
d) Fallopian tube T
e) Ovary
Q) 42. Removed enlarged ovary from
young woman showing cystic lesion with
presence of blood, hemosiderin laden
macrophages and broken endometrial
glands on that microscopic examination.
What would be probable diagnosis in
such as case ?
a) Follicular cyst
b) Luteal cyst
c) PCOD
d) Chocolate cyst T
e) Serous cyst adenoma
Q) 43. Rt: BREAST lumpectomy performed
on young female showed acini arranged
in intracanalicular pattern and loose
fibroblastic stroma. What would be
probable diagnosis in such case ?
a) Fibroadenoma
b) Infiltrating ductal carcinoma T
c) Medullary carcinoma
d) Lobular carcinoma
e) Paget disease
Q) 44. Endometrial biopsy for unrecorded
cause was performed on 60 year old lady
which showed atrophic Endometrium. A
decade later this lady developed bleeding
P/V and endometrial biopsy revealed
malignancy with P53 suppression on
genetic analysis. What would be
probable diagnosis in such case ?
a) Type l- adenocarcinoma
b) Type ll- adenocarcinoma T
c) carcino sarcoma
d) Adeno sacrcoma
e) Leiomyosarcoma
Q) 45. Young female with enlarged
thyroid and cervical lymphadenopathy,
when biopsied of thyroid showed
malignancy comprising of pleomorphic
cells with orphan annic eye nuclei . What
would be most likely diagnosis in such a
case ?
a) Papillary carcinoma T
b) Follicular carcinoma
c) Medullary carcinoma
d) Anaplastic carcinoma
e) Metastases
Q) 46. Very rare congenital cardiac Q) 50. Rapidly progressive
malformation is ? glomerulonephritis is histologicaly
characterized by ?
a) VSD
b) ASD a) Endothelial cell proliferation
c) Pulmonary stenosis b) Mesangial cell proliferation
d) Tricuspid atresia c) formation of crescents in the urinary
e) Aortic stenosis space T
d) Focal hyalinization of glomerular space
Q) 47. Which of the following is most e) wire loop formation
unlikely regarding major prognostic
criteria for breast cancer ? Q) 51. Electronic microscopy showing
prominent deposit between the
a) IN situ disease podocytes and the basement membrane
b) Distant metastasis T of the glomerular capillaries are most
c) Tumor grade likely related to infection with ?
d) Locally advanced disese
e) Tumor size a) Escherichia
b) Klebsielia
Q) 48. Most common site of formation of c) Neisseria
stone in urinary tract is ? d) Pseudomonas
e) Streptococcus T
a) Kidney T
b) ureter Q) 52. A 41 years old man complained of
c) urinary bladder swollen ankles. Physical examination
d) urethra revealed marked lower extremely edema
e) none of above and periorbital swelling. Urine dipstick
was 4+ positive for protein but negative
Q) 49. Most common malignant surface for blood and glucose. 24 hours urine
epithelial tumor of ovary is ? collection showed proteinuria of 5
mg/day. The diagnosis is ?
a) Brenner tumor
b) serous cyst adenofibroma a) Diabetic nephropathy
c) serous cyst adenocarcinoma T b) Membranoproliferative
d) clear cell tumor glomerulonephritis
e) Endometroid carcinoma c) Membranous glomerulonephritis T
d) Minimal change disease
e) Berger disease
Q) 53. Cushing disease is feature of ?
a) chromophobe adenoma of pituitary
gland
b) Acidophilic adenoma of pituitary gland
c) Basophilic adenoma of pituitary gland
d) Non-secreting adenoma of pituitary
gland
e) Corticotroph cell adenoma of pituitary
gland T
Q) 54. In early diagnosed case of
adenoma of adrenal gland with raised
steroid level having also associated
symptoms including nervousness,
palpitation and heat intolerance.
These symptoms are best explained by ?
a) psychological disturbance
b) Low thyroxine binding globulin T
c) Raised blood sugar
d) Electrolyte imbalance
e) Tumor mass
Q) 55. An eosinophil adenoma of the
anterior pituitary gland with elevated
GrH is most likely associated with all of
the following features, except ?
a) Premature closure of epiphysis
b) Enlargement of cell turcica
c) Hypertrophy and hyperplasia of soft
tissue throughout body
d) Impaired glucose tolerance
e) Excessive growth of acral parts T
Q) 56. Immune complex mediated
vasculitis all of the following , the most
unlikely would be ?
a) Hepatitis B & C induced vasculitis T
b) Henochschnolienpurpura
c) Drug induced vasculitis
d) Cryoglobulinemia
e) Churg Strauss syndrome
Q) 57. P-ANCA is typically found in ?
a) Wegner granulomatosis
b) Churg Strauss syndrome T
c) Good pasture syndrome
d) Cryoglobulinemia
e) Henochschonleinpurpura
Q) 58. Which of the following is direct
antibody mediated vasculitis ?
a) Kawasaki disease T
b) Churg Strauss syndrome
c) Sting induced vasculitis
d) Cryoglobulinemia
e) SLE arteritis
Q) 59. Plaque disruption is always absent
in ?
a) Stable angina T
b) Unstable angina
c) Subendocardial infarction
d) Sudden death
e) Transmural infarction
Q) 60. Aschoff's nodules shows the
presence of ?
a) Coagulation necrosis
b) Aggregates of lymphocytes
b) Multinucleated gaint cells T
c) Numerous plasma cells
d) Marked fibrosis
Q) 61. Heart failure cells are ? Q) 65. The most common cause of
Hypothyroidism ?
a) Swollen myocardial failure cell in heart
b) Degeneration cell in myocardial a) Colloid goiter
infarction b) Graves Disease
c) Haemosiderin laden macrophage in c) Hashimoto thyroditis T
chronic pulmonary congestion T d) Follicular carcinoma
d) Aschoff cell e) Medulary carcinoma
e) Degenerated macrophage
Q) 66. 40 % of Somatotroph (Growth
Q) 62. A 6 year old boy presents with hormone) pituitary adenoma bears ?
fever, and abdominal mass which has
growen rapidly over the last four months, a) P53-mutation
accompanied by weight loss. Ultrasound b) MEN1- mutation
confirmed a solid space occupying lesion c) P16- mutation
in the kidney. The diagnosis is ? d) GNAS-mutation T
e) Mutation of all above
a) Renal cell carcinoma
b) Transitional cell carcinoma of kidney Q) 67. Most common microbiological
c) Squamous cell carcinoma of renal agent in Pid is ?
pelvic
d) Wilmtumor T a) Staphylococcus
e) Hyronephrosis b) Gonococcus T
c) Tuberculosis
Q) 63. Acute nephritic syndrome is d) Trichomonasvesiculosus
dominated by acute onset of ? e) Candida albicans

a) proteinuria Q) 68. Acute left ventricular failure is

b) Hematuria T accompanied by ?
c) Oedema
d) Hypertension a) Decrease in pulmonary blood value
e) Hypoproteinemia b) Normal jugular venous pressure
c) Generalized vasodilation
Q) 64. Failure of the uterus to develop is d) Ankle oedema
directly related to the failure of which e) Pulmonary oedema T
one of the following Embroyonic
structures ?

a) Urogenital ridge
b) Mesonephric duct
c) para-mesonephric duct T
d) Metanephric duct
e) Epoophoron
Q) 69. Which of the following is not
feature of atherosclerosis ?
a) Lipid deposit in smooth muscles
b) Excessive collagen deposited intimae
c) Calcification occurs
d) Contraction of blood vessels occurs T
e) Disintegration of internal elastic
lamina
Q) 70. UTI due to B. proteus most likely
produced which of the following stones ?
a) Calcium Oxalate
b) Calcium phosphate
c) Magnesium aluminium phosphate T
d) Cystine
e) Carbonate
Q) 71. A 3 years old child suffering from
testicular mass. Histopathlogical
examination reveals medium sized
cuboidal cells arranged into lace like
pattern, papillary structures cord. The
schiller Duval bodies and hyaline like
globules are present. This child is
suffering from ?
a) Seminoma
b) Spermatocytic seminoma
c) Emnryonal carcinoma
d) Yolk sac tumor T
e) Immature teratoma
Q) 72. A 50 years old male reveal a 5 cm
nodular mass in the urinary bladder wall.
Histopathological examination reveals
neoplastic cells with large
hyperchromatic nuclei, eosinophilic
cytoplasm and typical and atypical
mitoses. There is loss of polarity and
dyscohesiveness. All features favour.
a) High grade urothelial carcinoma T
b) Carcinoma in Situ
c) Low grade urothelial carcinoma
d) Papillary urothelial neoplasm of low
malignant potential
e) Papiloma
Q) 73. 30 years female complain of
secondary infertility and presents with
colicky abdominal pain and Dysmenorhea
which one of the following is common
cause ?
a) Leiomyoma
b) PID
c) An ovulatory cycles
d) Endometrial hyperplasia
e) Endometriosis T
Q) 74. A 40 years old female consults a
doctor, complaining of tachycardia
palpitations and protrusion of eye ball (
exophthalmos). Laboratory
investigations reveals increased level of
free T3 and free T4. The most likely
diagnosis is ?
a) Toxic adenoma
b) Neonatal thyrotoxicosis associated
with maternal graves disease
c) Iodine induced hyperthyroidism
d) Toxic multinodulargoiter
e) Graves Disease T
Q) 75. A 10 years old child is diagnosed as
a case of hyperthyroidism. Laboratory
investigations helpful in the diagnosis
reveal ?
a) Increased TSH level and decreased T4
level
b) Decreased TSH level and Increased T4
level T
c) Increased T3 level and decreased T4
level
d) Increased T3 level and increased T4
level
e) Decreased T3 level and Decreased T4
level
Q) 76. A 55- year old woman has noted
the increasing prominence of dilated
superfiscial veins over both lower legs for
the past 5 years. Physical examination
shows temperature of 37°C, pulse of
70/min, respirations of 14/min, and
blood pressure of 125/185 mmhg. There
is no pain, Swelling, or tenderness in
either lower leg. Which of the following
complications is most likely to occur as a
Consequence of this condition ?
a) Stasis dermatitis T
b) Gangrenous necrosis of the lower legs
c) Pulmonary thromboembolism
d) Disseminated intravascular
coagulation
e) Atrophy of the lower leg muscles
Q) 77. A patient presents with fever,
flank pain, dysuria, Costovertebral angle
tenderness. Laboratory findings indicate
pyuria with pus cell casts. Suggestive
diagnosis is ?
a) Acute glomerulonephritis
b) Nephrotic syndrome
c) Acute pyelonephritis T
d) Nephritic syndrome
e) Chronic renal failure
Q) 78. Renal cell carcinoma spread early
by which of the following route ?
a) Renal artery
b) Local spread
c) Nervous
d) Lymphatics
e) Renal vein T
Q) 79. Rapidly progressive
glomerulonephritis is histopathlogically
characterized by ?
a) Endothelial cell proliferation
b) Mesangial cell proliferation
c) Formation of crescents in the urinary
space T
d) Focal hyalinization of glomerular loops
e) Wire loop formation
Q) 80. Which of the following congenital
renal diseases is inherited as an
autosomal dominant trait ?
a) Infantile polycystic kidney disease
b) Medullary sponge kidney
c) Medullary cystic kidney disease
complex
d) Cystic renal dysplasia
e) Adult polycystic kidney disease T
Q) 81. During a routine physical
exami8nation, an old is found to have a
small mass in his abdomen. Angiograph
reveals aneurysmal dilation ( about 5
cms) of aorta distal to renal arteries.
Which of the following is most likely
cause of this aneurysm ?
a) Hypertension
b) A previous syphilitic infection
c) Atherosclerosis T
d) A congenital defect
e) Trauma
Q) 82. In Lactating mother most common
cause of painful lump is ?
a) Periductal mastitis
b) Fibroadenoma
c) Acute mastitis T
d) Mammary duct ectasia
e) Fat necrosis
Q) 83. A 27 years old female requests a
mammogram her mother and sister died
of breast cancer which one of the
following is major risk factor for breast
cancer ?
a) Multiparty
b) High fiber diet
c) Oral Contraceptive use
d) BRCA-1 mutation T
e) Bilateral Fibroadenoma
Q) 84. A 55 years old male suffering from
prostate enlargement. Biopsy
examination reveals varaible sized glands
lined by double layer of epithelial cells
Showing Papillary infolding’s. The glands
are separated by fibromuscular stroma.
The most likely diagnosis is ?
a) Chronic bacterial prostatitis
b) Acute bacterial Prostatitis
c) Benign prostate hyperplasia T
d) Granulomatous Prostatitis
e) Adenocarcinoma of Prostate
Q) 85. Which one of the following tumor
marker is used for prognosis of surface
epithelial tumor of ovary ?
a) CA-115
b) Alpha fetoprotein
c) CA-125 T
d) CEA level
e) Beta HCG
Q) 86. Which one of the following is not
correct association of tumor marker with
corresponding tumor ?
a) Sertolileyding cell tumor-androgen
b) Choriocarcinoma-Alpha fetoprotein T
c) Serous cyst adenocarcinoma-CA-125
d) Granuloma Cell-tumor-oestrogen
e) Dysgerminoma-Beta HCG
Q) 87. If patient has TSH decreased, T4
and T3 normal. What is your diagnosis ?
a) Hyperthyroidism
b) Hypothyroidism
c) Subclinical Hyperthyroidism
d) Subclinical Hypothyroidism
e) Report is normal T
Q) 88. A 55 years old male is suffering
from difficulty in passing urine.
Ultrasound examination reveals
enlargement of Prostate. What is the
most common site of benign prostate
hyperplasia ?
a) Peripheral zone
b) Central zone
c) Periurethral zone
d) Transitional zone T
Q) 93. Which of the following HPV viruses
are known to cause cervical cancer ?
a) All types of HPV viruses
b) HPV type 16 and type 18 T
c) HPV type 8 and type 11
d) Low risk HPV viruses
e) None of above
Q) 94. Ovarian tumor most likely to have
Virilising effects ?

Q) 90. After myocardial infarction lab a) Sertolileydingtumor T

reports shows an elevation of CKM & LDH b) Brenner tumor
. What is the time interval passed since c) Cystadenoma
that attack ? d) Mucinous adenocarcinoma
e) Dysgerminoma
a) 3 hours
b) 6 hours Q) 95. Yolk sac tumor is most commonly
c) 12 hours T seen ?
d) 18 hours
e) 24 hours a) After 50 years of the age
b) Up to the 30 years of the age
Q) 91. Bilateral polycystic kidney is ? c) Up to the 3 years of the age T
d) Seen in all age groups
a) Autosomal dominant T e) No age limit
b) Autosomal recessive
c) X-linked Q) 96. Pure glucocorticoid or cortisol
d) Non Hereditary hormone is secreted from ?
e) Hereditary
a) Hypothalamus
Q) 92. All are epithelial Ovarian tumor b) Pituitary glands T
except ? c) Thyroid glands
d) Adrenal gland
a) Brenner tumor e) Pineal gland
b) Mucinous adenocarcinoma
c) Endometriodtumor Q) 97. Precise cause of Cryptorchoidism is
d) Teratoma T most likely ?
e) Serous cyst adenocarcinoma
a) Idiopathic
b) Short spermatic cord
c) Deficiency of LH
d) Deficiency of testosterone T
e) Trisomy 13

Q) 98. Lymph nodes are first affected by 102 - Organism is involved in

carcinoma of Prostate is most likely ? pathogenesis of Rheumatic fever :

a) Perivesical A. Streptococcus pyogenes T

b) Iliac B. Streptococcus viridians
c) Inguinal C. Streptococcus agalactiae
d) Obturator T D. Staphylococcus aureus
e) Sacral E. Pneumococcus

Q) 99. The most common type of 103 - The clinical complex of nephritic
prostatitis in these days is ? syndrome is usually characterized by all
of the following findings except :
a) Acute bacterial
b) Acute abacterial A. Protein Urea > 3.5 gm/day T
c) Chronic bacterial B. Hypertension
d) Chronic abacterial T C. Acute onset
e) Fungal D. Hematuria with red blood cell casts
E. Some degree of oliguria
Q) 100. When a solitary cyst develops in
breast, the usual anatomical site is ? 104 - Aschof bodies are the
characteristics morphological feature of :
a) Ductule T
b) Lobule A. Rheumatic fever T
c) Terminal duct B. Marfan syndrome
d) Lacteferous sinus C. Infective endocarditis
e) Segmental duct D. Mitral degeneration
E. SLE
101 - Renal Cell Carcinoma spread early
105 - Rapidly progressive
by which of the following route :
glomerulonephritis is histologicaly
characterized by :
A. Renal vein T
B. Renal artery
A. Formation of crescents in the urinary
C. Lymphatics
space T
D. Local spread
B. E. Coli proliferation
E. Nervous
C. Mesangial cell proliferation
D. Focal hyalinization glomerular space
E. Wire loop formation
106 - A 35 years old female develops
ocular disturbances cold with numbness
of fingers. Biopsy of aorta reveals
granulomatous inflammation of tunica
media with giant cell. The most probable
diagnosis :
A. Takayasu's arteritis T
B. Giant cell arteritis
C. Wegener's granulomatous
D. PAN
107 - Which of the following congenital
renal diseases is inherited as an
autosomal dominant trait :
A. Adult polycystic kidney disease T
B. Infantile polycystic kidney disease
C. Medullary cystic kidney disease
complex
D. Cystic renal dysplasia
E. Medullary sponge kidney
108 - A 60 years old women dies of tumor
that had involved the renal vein and
entired the inferior vena cava. Which one
of the following is characteristic
association of the neoplasm :
A. Hematuria T
B. Hypocalcemia
C. Tumor cells in urine
D. Typical bilateral involvement
E. Adrenal origin
109 - Which of the following is most likely
cause of clinical combination of
generalized oedema, hypoalbuminemia,
hypercholestrolemia in an adult whose
urine analysis shows marked proteinuria
with fatty casts :
A. Nephrotic syndrome T
B. Nephritic syndrome
C. Acute renal failure
D. Renal tubular defect
E. Urinary tract infection
110 - A patient presents with fever, flank
pain, dysuria, costovertebral angle
tenderness. Laboratory findings indicate
pyuria with pus cells casts. Suggestive
diagnosis is :
A. Acute pyelonephritis T
B. Acute glomerulonephritis
C. Nephrotic syndrome
D. Nephritic syndrome
E. Chronic renal failure
111 - A boy brought to emergency ward,
after a road traffic accident, present with
hypovolumic shock, low urine output.
Laboratory findings are normal platelets,
elevated serum creatinine and BUN
levels. Findings favor diagnosis of :
A. PrerenalAzotemia T
B. Renal Azotemia
C. PostrenalAzotemia
D. Hemolytic uremic syndrome
E. Thrombotic thrombocytopenic purpura
112 - After myocardial infarction lab 116 - Thromboangitis obliterans (
reports shows an elevation of CKM & Buerger disease ) is strongly related with
LDH. What is time interval passed since which of the following :
that attack :
A. Cigarette smoking T
A. 12 hours T B. Hypertension
B. 18 hours C. Hyperlipidemia
C. 24 hours D. Decrease intake of fruits
D. 03 hours E. Decrease vitamin and zinc intake
E. 06 hours
117 - Bilateral polycystic kidney is :
113 - Acute left ventricular failure is
accompained by : A. Autosomal dominant T
B. Autosomal recessive
A. Pulmonary oedema T C. X - linked
B. Ankle oedema D. Non hereditary
C. Generalized vasodilation E. Hereditary
D. Normal jugular venous pressure
E. Decrease in pulmonary blood value 118 - A 02 years old boy with visible
abdominal distension is found to have
114 - UTI due to B. Proteus most likely enormous left side flank mass arising
produces which of the following stones : from it but dwarfism left kidney. The
most likely diagnosis is :
A. Magnesium aluminium phosphate T
B. Calcium phosphate A. Wilmstumor T
C. Calcium oxalate B. Polycystic kidney
D. Cystine C. Angiomyolipoma
E. Carbonate D. Renal cell carcinoma
E. Transitional cell carcinoma
115 - Regarding renal calculi, the cause of
cystine stone is : 119 - Which of the following is most likely
cause of clinical combination of
A. Genetic defect in reabsorption of generalized oedema, hypoalbuminemia,
amino acids T hypercholestrolemia, in an adult whose
B. Sarcoidosis urine analysis shows marked protein urea
C. Hyperparathyroidism with fatty casts :
D. Infection by urea splitting organism
E. Acidic urine pH < 5.5 A. Nephrotic syndrome T
B. Nephritic syndrome
C. Acute renal failure
D. Renal tubular defect
E. Urinary tract infection
120 - The most commonly feared D. Proteinuria
consequence of long standing chronic pid E. Convulsions
is :
125 - Schiller - Duval bodies are
A. Infertility T pathognomonic of :
B. Intestinal obstruction
C. Bacteremia A. Endometrial sinus tumor T
D. Vulvovaginalis B. Wilm'stumor
E. Paritonitis C. Choriocarcinoma
D. Clear cell adenocarcinoma of cervix
121 - Condition associated with E. Dysgerminoma
endometrial hyperplasia except :
126 - Which of the following epithelia is
A. Amenorrhea T most resistant to gonorrhea :
B. Menopause
C. Polycystic ovarian disease A. Vagina of sexually mature women T
D. Prolonged administration of estrogen B. Vagina in pre pubertal girls
E. Functioning granulose of cell tumor of C. Endocervix
ovary D. Endometrium
E. Fallopian tube
122 - Higher frequency of carcinoma of
endometrium is seen with all except : 127 - The most common cause of death in
advanced cervical carcinoma is :
A. Tb T
B. Hypertension A. Renal failure T
C. Obesity B. Brain metastases
D. Disease C. Lung metastases
E. Infertility D. Adrenal cortical failure
E. Vertebral fractures
123 - Which type of ovarian tumor has
the highest frequency of occurring : 128 - When a solitary cyst develops in
breast, the usual anatomical site is :
A. Surface epithelial cell tumors T
B. Germ cell tumor A. Ductule T
C. Sex - cord stromal tumors B. Lobule
D. Metastatic non ovarian cancer C. Terminal duct
E. Malignant tumor D. Lacteferous sinus
E. Segmental duct
124 - All are clincal presentation of
eclampsia except :

A. Anemia T
B. Hypertension
C. Edema
129 - The survival rate for which of the E. Haploid
breast carcinoma is most likely highest :
134 - Chronic bacterial prostatis is most
A. Intraductal carcinoma T likely caused by all except :
B. Medullary carcinoma
C. Colloid carcinoma A. Chlamydia T
D. Papillary carcinoma B. E.Coli
E. Infiltrating lobular carcinoma C. Pseudomonas
D. Staph aureus
130 - Longer disease free survival and E. Enterobacter
overall survival are expected in women
whose breast cancers show a high degree 135 - A patient come to physician with
or level of : the complains of weakness and easy
fatigability. The diagnosis of disease is
A. Estrogen receptors T Addison's disease how it occurs :
B. Nuclear atypia
C. Histologic grade A. Due to hyperpituitarism
D. EGF receptors B. Due to primary chronic adrenocortical
insufficiency T
131 - The most common type of C. Due to hypothyroidism
prostatitis in these days is : D. Due to hyperthyroidism
E. Due to hypercortisolism
A. Chronic abacterial T
B. Chronic bacterial 136 - Function of parathyroid hormone is
C. Acute abacterial to regulate the following :
D. Acute bacterial
E. Fungal A. Secretion from pituitary gland
B. Secretion from adrenal gland
132 - The lymph nodes are first affected C. secretion from thyroid gland
by carcinoma of prostate is most likely : D. Secretion from hypothelium
E. Regulate the serum calcium level T
A. Obturator T
B. Inguinal 137 - Pure glucocorticoid hormone or
C. Iliac cortisol secrated from :
D. Sacral
E. Perivesical A. Hypothalamus
B. Pituitary glands
133 - Prognosis is most likely better in C. Thyroid glands
prostatic cancer, when tumor cells are : D. Adrenal gland T
E. Pineal gland
A. Aneuploid T
B. Diploid
C. Tetraploid
D. Pentaploid
138 - Which one of the testicular tumors 143 - Which of thw following HPV viruses
is highly malignant : are known to cause cervical cancer :

A. Yolk sac tumor A. All types of HPV viruses

B. Seminoma B. HPV type 16 and type 18 T
C. Embryonal cell carcinoma C. HPV type 6 ans type 11
D. Choriocarcinoma T D. Low risk HPV viruses
E. Sertoli cell tumor E. None of above

139 - About 60% of testicular tumors are 144 - In patients with breast cancer, poor
composed of : prognostic factor include all of following
except :
A. Leyding cells
B. Sertoli cells A. Inflammation and swelling of breast
C. Yolk sac skin
D. Embryonal cells B. Tumor invading the skeletal muscle
E. Mixed germ cells T C. Metastases to > 3 axillary lymph nodes
D. Over expression of Her2/NEU
140 - The most histological type of E. Presence of estrogen receptors in
cervical cancer is : tumor T

A. Adenocarcinoma 145 - A 30 years old female complain of

B. Squamous cell carcinoma T colicky abdominal pain and
C. Endocervical polyp dysmenohrrea. On ultrasound
D. Endometriosis examination both ovaries are enlarged,
E. Cervical intraepithelial tumor cystic and chocolate brown in colour.
Which one of the following is possible
141 - All are epithelial ovarian tumor diagnosis :
except :
A. Endometriosis T
A. Brenner tumor B. Pelvic inflammatory disease
B. Mucinous adenocarcinoma C. Leiomyoma
C. Endometriodtumor D. Endometrial hyperplasia
D. Teratoma T E. Salpingo - oophritis
E. Serous cystadenocarcinoma

142 - Ovarian tumor most likely to have

virilizing effects :

A. Sertolileyding cell tumor T

B. Brenner tumor
C. Cystadenoma
D. Dysgerminona
E. Mucinous adenocarcinoma
146 - A patient with age of 30 years
shows lobulated bulky mass ten times the
size of normal testis. Its histopathological
examination shows large round to
polyhedral cells with distinct cell outlines,
watery appearing cytoplasm large
central nuclei with one or two prominent
nucleoli. What will be the diagnosis :
A. Embryonal cell carcinoma
B. Yolk sac tumor
C. Leyding cell tumor
D. Seminoma T
E. Sertoli cell tumor
147 - A 42 years old woman had a
hysterectomy because of uterine
enlargement. Histological examination
showed an exaggerated down growth of
endometrium into myometrium. The
most likely diagnosis is :
A. Adenosis
B. Adenomyosis T
C. Endometriosis
D. Endometritis
E. Cervicitis
148 - Bleeding from the nipple in a 45
years old woman, without a palpable
breast. Mass most likely would suggest :
A. Fibroadenoma
B. Sclerosing of adenosis
C. Fat necrosis
D. Intraductal papilloma T
E. Chronic cystic mastitis
149 - A lesion from the breast of a 60
year old woman contains a firm area 3
cm in diameter with irregular, ill - defined
margins. The lesion is densely fibrous and
gritty. The sectioned surface id gray,
slightly depressed and opaque. Cords of
fibrotic tissue extend irregularly into
surrounding adipose tissue. The most
likely diagnosis is :
A. Fat necrosis
B. Fibrocystic disease
C. Invasive ductal carcinoma T
D. Medullary carcinoma
E. Colloid carcinoma
150 - A 35 year breat feeding mother
complains of painful left breast lump. She
also give history of trauma by child head
during feeding. Which one of the
following is most likely diagnosis :
A. Acute mastitis T
B. Fibrocystic disease
C. Fibroadenoma
D. Carcinoma
E. Intraductal papilloma
151 - A 30 year female clinicaly presents
with hard irregular right breast lump.
Which one of the following is not
associated with increased risk of breast
cancer :
A. BRCA - 2 gene carrier
B. Family history of breast cancer
C. Biopsy results that show atypical
lobular hyperplasia
D. Breast feeding T
E. Biopsy result that show clinical ductal
carcinoma in situ
152 - A 50 year old female is suffering
from severe abdominal pain with
complains of nusea and vomiting.
Clinicaly the case is diagnosed as acute
pancreatitis. Which following laboratory
investigation will help in the diagnosis :
A. Increased level of serum amylase T
B. Decreased level of serum amylase
C. Decreased level of serum lipase
D. Increased serum insulin level
E. Increased level of glucokinase
153 - Yolk sac tumor is most commonly
seen :
A. After 50 years of the age
B. Upto 30 years of the age
C. Upto the 3 years of the age T
D. Seen in all age groups
E. No age limit
154 - A patient with moon like face,
buffalo hump (deposition of fat on back
and neck), with clincal manifestation of
hypertension and weight gain. What will
be most common diagnosis :
A. Addison's disease
B. Cushing disease T
C. Hypothyroidism
D. Hyperthyroidism
E. Hypopitutarism
155 - A 30 year old lady suffering from
enlarged thyroid histopathological report
reveals a well cirumscribed lesion of
thyroid with well formed intact capsule.
The most likely diagnosis :
A. Papillary carcinoma of thyroid
B. Follicular carcinoma of thyroid
C. Medullary carcinoma of thyroid
D. Multinodulargoiterot thyroid
E. Adenoma of thyroid T
156 - A 10 years old child is diagnosed as
case of hypothyroidism. Laboratory
investigations helpful in the diagnosis
reveal :
A. Increased TSH level and decreased T4
level T
B. Decreased TSH level and and increased
T4 level
C. Increased T3 level and decreased T4
level
D. Increased T3 level and increased T4
level
E. Decreased T3 level and decreased T4
level
157 - A 40 years old female consults a
doctor, complaning of tachycardia
palpitation and protrusion of eye - ball (
exophalmos). Laboratory investigations
reveals increased level of free T3 and free
T4. The most likely diagnosis is :
A. Toxic adenoma
B. Neonatal thyrotoxicosis associated
with maternal graves disease
C. Iodine induced hyperthyroidism
D. Toxic multinodulargoiter
E. Graves disease T
158 - A 17 years young lady come to 161 - Most common benign germ cell
doctor with a complaint of swelling in the tumor is :
cervical region of neck. Swelling was
excised, histopathological report reveals A. Mature cystic teratoma T
lymph node showing papillary process B. Serous cyst adenoma
with fibrovascular course lined by C. Yolk sac tumor
cuboidal epithelium. The cell contain D. Dysgerminona
orphan - Annie eye nuclei. The features E. Struma ovari
are in favour of :
162 - Which one of the following tests
A. Papillary carcinoma of thyroid assessing the best regarding thyroid
metastatic T functional status :
B. Medullary carcinoma of thyroid
metastatic A. TSH level T
C. Follicular carcinoma of thyroid B. Total T3 level
metastatic C. Total T4 level
D. Anaplastic carcinoma of thyroid D. Radioiodine scan
metastatic E. Fine needle aspiration
E. Follicular adenoma of thyroid
163 - Most common cause of
159 - The most commonly featured
haemorrhagic nipple discharge is :
complication of long standing chronic pid
is :
A. Intraductal papilloma T
B. Breast abscess
A. Infertility T
C. Galactocele
B. Peritonitis
D. Phyllodestumor
C. Bacteremia
E. Duct cell carcinoma
D. Intestinal obustruction
E. Vulvo vaginitis
164 - A 30 year female had pap smear
test which shows high grade
160 - Which of the following is not a risk
intraepithelial lesion. which one of the
factor endometrial carcinoma :
following is causative organism :
A. T.B T
A. HPV 16 & 18 T
B. Obesity
B. HIV
C. Diabetes
C. EBV
D. Hypertension
D. Herpes simplex virus
E. Infertility
E. Chlamydia
165 - 60 years female complains of
bilateral partly solid and cystic ovarian
tumor and present with ascites. Which
one of following is most common type :
A. Serous cyst adenocarcinoma T
B. Mucinous cyst adenocarcinoma
C. Teratocarcinoma
D. Clear cell carcinoma
E. Brenner tumor
166 - which type of ovarian tumor has the
highest frequency of occurring :
A. Surface epithelial cell tumor T
B. Germ cell tumor
C. Malignant tumor
D. Sex cord stromal tumor
E. Metastatic non ovarian cancer
167 - Which one of the following is
estrogen producing tumor of ovary :
A. Granulose cell tumor T
B. Mucinous cyst adenoma
C. Teratoma
D. Brenner tumor
E. Endometrial carcinoma
168 - A 06 year old boy have a 2 cm
spongy, dull red, circumscribed lesion on
face since birth. The lesion is excised, and
its microscopic appearance shows
dilated, endothelium - lined spaces filled
with RBCs. Most likely diagnosis is :
A. Lymphangioma T
B. Kaposi sarcoma
C. Angio sarcoma
D. Hemangioma
E. Telangiectasia
169 - A 70 year old woman has been
bedridden for last one month. Physical
examination shows swelling and
tenderness of the right leg. Which
worsens when she raises or moves the
leg. Which of the following terms best
describes the condition involving the
patients right leg :
A. Thrombophlebitis T
B. Lymphedema
C. Disseminated intravascular
coagulopathy
D. Thromboangitis obliterans
E. Varcoseveina
170 - A 30 year old woman had painful
thrombosis of superficial veins of the
lower legs, her fingers become blue and
cold. One toe becomes gangrenous and is
amputated, diagnoses as a case of
Thromboangitis obliterans. Which of the
following is associated with this disease :
A. Cigarette smoking T
B. Hypertension
C. Hyperlipidemia
D. Decrease intake of fruits
E. Decrease vitamin and zinc intake
171 - Which of the following thyroid
tumor produces amyloid :
A. Medullary carcinoma T
B. Follicular adenoma
C. Follicular carcinoma
D. Papillary carcinoma
E. Anaplastic carcinoma
172 - During a routine physical 175 - Which of the following disease is
examination, an old man is found to have not caused by mutations in CTLA4 and
a small mass in his abdomen. Angiograph PTPN22 gene :
reveals aneurysmal dilation of ( about 5
cms) of aorta distal to renal arteries. A. Granulomatous (De
Which of the following is most likely Quervainthyroiditid) T
cause of this aneurysm : B. Graves disease
C. Addison disease
A. Atherosclerosis T D. Hashimoto thyroidits
B. Hypertension E. Type 1 - diabetes mellitus
C. A congenital defect
D. Trauma
176 - Myocardial infarction is most likely
E. A previous syphilitic infection
complication of :
173 - A 60 years old male comes to
clinician with complaint of retention of
☆ Kawasaki disease
urine. Ultrasound examination reveals
177 - The leading cause of mortality in
enlarged prostate. Name the most
ischemic heart disease is sudden death
common zone/region from which benign
which is due to :
prostate hyperplasia arises :

A. Transitional zone T ☆ Ventricular fibrillation

B. Peripheral zone
C. Central zone 178 - Most common tumor arising from
D. Periurethral zone ovarian surface epithelium is :

174 - A 70 years old male suffering from ☆ serous tumor

adenocarcinoma of prostate reveals
following microscopic features. Which of 179 - Dyspnea, orthoponea and
the following is not a feature of prostate paraxyomaldypnea are the characteristic
adenocarcinoma : clinial features of :

A. Glands are lined by double layer ☆ left sided heart failure

epithelium T
B. Glands are smaller and crowded 180 - In rheumatic fever most common
C. Nuclei are large with one or more involved valve is :
prominent nuclei
D. Perineuralinvasional is present ☆ Mitral valve
E. On immunohistochemistry neoplastic
cells are positive for alpha methyl acyl co
enzyme A recemase
181 - Aschoff bodies are characteristic thickening of basement membrane of
morphological features of : glomerulus is due to :

☆ Rheumatic fever ☆ Sub Epithelial Deposits

182 - Most benign hyperplasia arises 190 - A male suffering from arthritis of
from : long duration. Now he develops
symptoms of cushing syndrome. What is
☆ Transition zone most likely cause :

183 - Most common site of prostate ☆ Corticosteroid therapy

cancer is from :
191 - Acute post streptococcal
☆ Peripheral zone glomerulonephritis presents with :

184 - The most common cause of urinary ☆ Acute Nephritic Syndrome

tract infection is :
192 - Paucci immune crescentic
☆E.Coli glomerulonephritis is characterized by :

185 - The most common malignant tumor ☆Anticytoplasmic neutrophilic antibodies

of the kidney is : ANCA

☆ Renal cell carcinoma 193 - The main Androgen in prostate is :

186 - Hyman's is inolved in immune ☆Dihydrotestosterone

complex formation is :
194 - Most hyperplasia arises in which
☆ membranous glomerulonephropathy zone of prostate :

187 - Activation of alternative ☆ Transitional Zone

complement pathway occurs in :
195 - Most carcinoma arises in which
☆membranouz proliferative zone of prostate :
glomerulonephropathy
☆ Peripheral zone
188 - Spitting of the basement membrane
due to mesangial interposition is seen in : 196 - The most common cause of
bacterial prostatitis is :
☆Membrano - proliferative
glomerulonephritis ☆ E. Coli

189 - The most common type of

197 - The presence of alpha fetoprotein in 206 - Which of the following is estrogen
tumor cells is highly characteristic of : producing tumor of ovary :

☆ Yolk Sac Testicular Tumor ☆ Granulosa cell tumor

207 - Most common benign germ cell
198 - Seminomas are : tumor is :
☆ Radiosensitive testicular tumor ☆ Mature Cystic Teratoma

199 - NoNSeminomatous are : 208 - Increase Secretion of ACTH

hormone causes :
☆ Radio Resistant Testicular Tumor
☆ Cushing syndrome
200 - Teratoma of tetes arises from :
209 - The most common type of renal cell
☆ More than one germ cell layers carcinoma is :

201 - P - ANCA is typically found in : ☆ Clear cell carcinoma

☆Churg Strauss syndrome 210 - The most important risk factor for
renal cell carcinoma is :
202 - Aschoff nodules show the presence
of : ☆ Tobacco

☆ Aggregates of lymphocytes 211 - Hyperpituitarism is due to :

203 - The most common cause of ☆ Adenoma of Pituitary Gland

abdominal aortic aneurysm is :
212 - Ankle edema and pretibial edema is
☆ Atherosclerosis hallmark of :

204 - The most common cause ☆ Right sides heart failure

hemorrhagic nipple discharge is :
213 - The most Serious complication of
☆ Ductal cell carcinoma deep venous thrombosis is :

205 - Which of the following genetic ☆ Pulmonary Embolism

mutations are commonly seen in breast
cancer : 214 - Lymphangitis is most commonly
caused by :
☆ BRCA - 1
☆ Group A beta hemolytic streptococci
215 - In varicose veins typically involved
vessels are :
☆ Superficial veins upper and lower legs
216 - The most common cause of aortic
dissection and thoracic aortic aneurysm is
: D. Marfan syndrome
☆ Hypertension
217 - Thrombophlebitis obliterans (burger
disease) is clincal condition of vascular
insufficiency, almost exclusively
associated with :
☆ Heavy Smoking
218 - Calcium stones are :
☆ Radiopaque
219 - Uric acide stones are :
☆ Radiolucent
220 - There are four types of renal stone
and most common type of stone is :
☆ Calcium calculi
221 - Following are causes of sudden
cardiac death Except :
A. Aortic valve prolapsed
B. Mitral valve prolapsed
C. Myocarditis
D. Pulmonary hypertension
E. Pulmonary valve prolapsed T
222 - Ring abscess, systemic emboli and
septic infarcts all are the complication of
which of the following disease :
A. Rheumatic heart disease
B. Libman sacks endocarditis
C. Non bacterial thrombotic endocarditis
E. Infective endocarditis T
223 - Which of the following type of
angina also reffered to as pre infarction
angina :
A. Stable angina
B. Prinzmetal angina
C. Unstable angina T
D. Simple angina
E. Compound angina
224 - Acute coronary syndrome inclue all
of the following Except :
A. Acute MI
B. Unstable angina
C. Sudden cardiac death
D. Stable angina T
E. All of the above
225 - Which of the following group of
drugs are thought to stabilize plaques to
coronary arteries by their lipid lowering
effect as well as by reducing plaques :
A. NSAIDS
B. Skeletal muscle relaxant
C. Statins T
D. Antibiotics
E. Steroids
226 - More than 90% cases of MI are due 230 - Which of the following kidney
to : tumor is present in patient with tuberous
sclerosis and has a risk of spontaneous
A. DIC hemorrhage :
B. Hemolytic uremic syndrome
C. Infected endocarditis A. Oncocytoma
D. Athresclerotic coronary arterial B. Papillary adenoma
obstruction T C. Angiomyolipoma T
E. Vasculitis D. Wilmtumor
E. Clear cell carcinoma
227 - Which of the following is most
frequent congenital cardiac 231 - Kidney stones associated with
malformation : gount are :

A. VSD T A. Calcium
B. ASD B. Uric acid T
C. Tetralogy of Fallot C. Oxalate
D. Coarctation of aorta D. Cystine
E. PDA E. Magnesium, Amonium phosphate

228 - Which of bladder tumor that is
common in infancy and childhood :
A. Carcinoma in situ
B. Papilloma
C. Low grade urothelial carcinoma
D. High grade urothelial carcinoma
E. Sarcoma botryoides T
229 - Oninon skinning and fibrinoid
necrosis of renal arterioles are features of
: 233 - A 60 years old lady with lethargy,
A. Diabetic nephropathy
B. Lupus nephropathy
C. Renal artery stenosis
D. Benign nephrosclerosis
E. Malignant nephrosclerosis T
232 - A male suffering from arthritis of
long duration. Now he develops
symptoms of cushing syndrome. What is
most likely cause :
A. Adrenal carcinoma
B. Ectopic ACTH production
C. Adrenal adenoma
D. Pituitary adenoma
E. Corticosteroid therapy T
nusea and weakness. Her plasms
corticotropin is above normal and cortisol
is below normal. What is your diagnosis :
A. Cushing's disease
B. Ectopic corticotropin - producing tumor
C. Secondary renal insufficiency
D. Congenital adrenal hyperplasia
E. Addison's disease
234 - Renal cell carcinoma spread early 238 - Circumferential subendocadial
by which of the following route : infarcts are typically a consequence of :
A. Coronary spasm
A. Renal artery
B. Inadequate anastomotic circulation
B. Local spread
C. Hypoperfusion of the heart in shock
C. Nervous
D. Cardiac tamponade
D. Lymphatics
E. Mitral stenosis
E. Renal vien T
239 - Urine analysis of a patient reveal
235 - Aschoff bodies are characteristic
red cells, casts, epithelial cells and
morphological features of which of the
albumin. The underlying cause is :
following condition :
A. Urinary tract infection
A. Morfan syndrome
B. Renal calculus
B. Infective endocarditis
C. Interstitial nephritis T
C. Rheumatic fever T
D. Nephrotic syndrome
D. SLE
E. Glomerulonephritis
236 - Dyspnea, orthoponea and
240 - A 3 years girl presents with
paraxyomaldypnea are the characteristic
generalized edema, shortly after
clinial features of :
recovering from upper respiratory tract
infection lab study reveal marked
A. Left sided heart failure T
albumin urea,hypoalbuminemia and
B. Right sided heart failure
hyperlipidemia. The most likely diagnosis
C. Hypoxic encephalopathy
is :
D. Pre renal azotemia
E. Ascitis
A. Minimal change disease T
B. Membranous glomerulonephritis
237 - The jones major criteria for
C. Post streptococcal glomerulonephritiS
diagnosing rheumatic fever inclue all of
D. Focal segmented glomerulosclerosis
the following except :
E. Rapidly progressive glomerulonephritis
A. Carditis
241 - A 2 years old boy with visible
B. Aortitis T
abdominal distension is found to have
C. Polyarthritis
enormous left side flank mass arising
D. Chorea
from left kidney. The most likely
E. Erythema marginatum
diagnosis is :

A. Angiomyolipoma
B. Polycystic kidney
C. Renal cell carcinoma
D. Transitional cell carcinoma
E. Wilmstumor T
242 - Which of the following is most likely
cause of clinical combination of
generalized oedema, hypoalbuminemia,
hypercholesterolemia in adult whose
urine analysis shows marked proteinurea
with fatty casts :
A. Nephritic syndrome
B. Nephrotic syndrome T
C. Acute renal failure
D. Renal tubular defect
E. Urinary tract infection
243 - A 7 year old child presents with
hypoalbuminemia, edema,
hyperlipidemia and proteinurea. The
patient is given steroid therapy and the
disease goes away. What is key
morphological feature of patient's
disease :
A. Fusion of foot processes T
B. Destruction of the basement
membrane
C. Destruction of glomerulus
D. Infiltration of area with lymphocytes
E. Tramtrak appearance of basement
membrane
244 - A 50 years female presents with
proteinuria, and edema. Biopsy shows
sclerosis in some loops of some glomeruli.
What is your diagnosis :
A. Diabetic nephropathy
B. IgA nephropathy
C. Membranous nephropathy
D. Focal segmental glomerulosclerosis T
E. Membrano - proliferative glomerulo -
nephritis
245 - A boy brought to emergency ward,
after a road traffic accident, presents
with hypovolumic shock, low urince
output. Laboratory findings are normal
platelets, elevated serum creatinine and
BUN levels. Findings favor diagnosis of :
A. Renal azotemia
B. Pre - Renal azotemia T
C. Post - Renal azotemia
D. Hemolytic uremic syndrome
E. Thrombotic thrombocytopenic purpura
246 - A patient presents with hematuria,
proteinurea, and edema. C3 levels are
low. Basement membrane reveals
thickening and tram - tracking. He is
diagnosed with type 1 of MPGN. Electron
dense deposition is most commonly seen
in :
A. Mesangium
B. The loops of henle
C. The subepithelial area
D. The subendothelial area T
E. The subendothelial area
247 - A 60 years old man who is a known
hypertensive and diabetic, develops
sudden severe constricting chest pain
with profuse sweating and is brought to
hospital emergency. Which lab
investigation will be helpful for diagnosis
of his condition :
A. LDH
B. SGOT
C. CKMB
D. Troponin I & T (T)
E. C - reactive protein
248 - If the antimitochondrial antibody (
AMA) is negative, transaminases are not
elevated and cholangiography is
unremarkable. The most likely etiology
for juandice in a 55 year old female is :
A. Chronic active hepatitis
B. Primary biliary cirrhosis
C. Chronic persistent hepatitis
D. Cystic fibrosis of the pancreas
E. Carcinoma of the head of pancreas
249 - A patient presents with fever, flank
pain, dysuria, costovertebral angle
tenderness. Laboratory findings indicate
pyuria with pus cell casts. Suggestive
diagnosis is :
A. Acute pyelonephritis T
B. Nephrotic syndrome
C. Nephritic syndrome
D. Chronic renal failure
E. Acute glomerulonephritis
250 - Characteristic histological findings
of rapidly progressive
glomerulonephritis:
A. Crescent formation
B. Sub - epithelial electron dense hump
C. Linear pattern of immunoflorescence
D. Basement membrane spikes on silver
staining
E. Tram - tract splitting of glomerular
basement membrane
251 - The most common type of
prostatitis in these days :
A. Acute bacterial
B. Acute abacterial
C. Chronic bacterial
D. Chronic abacterial T
E. Fungal
252 - Prognosis is most likely better in
prostatic cancer, when tumour cells are :
A. Diploid
B. Haploid
C. Aneuploid T
D. Tetraploid
E. Pentaploid
253 - A 25 years male with complains of
testicular mass. Histopathological
examination shows polygonal cells with
distinct outlines, clear cytoplasm and
vesicular nuclei. The most likely diagnosis
is :
A. Teratoma
B. Seminoma T
C. Yolk sax tumor
D. Immature teratoma
E. Embryonal carcinoma
254 - A 30 years female complain of
swelling in neck. On examination it was a
thyroid swelling. Histopathological
examination reveals follicular adenoma.
Which is characteristic features of
follicular adenoma which differentiate it
from follicular carcinoma :
A. Areas of fibrosis
B. Areas of calcification
C. Invasion of capsular vessels and vessels
beyond the capsule
D. Invasion of capsule and extra thyroidal
tissue by neoplastic cells
E. Presence of intact well formed capsule
completely encircling the tumor T
255 - A 30 years old lady is suffering from 258 - Large ovarian cystic mass was
Graves disease. Which laboratory test removed on naked eye examination it
favors Graves disease : shows cheesy material, hair, teeth and
bone. Which is histological diagnosis :
A. Decreased level of free T3 and freeT4
B. Increased level of TSH free T3 , freeT4 A. Struma ovari
C.Increased level T4 of TSH and decreased B. Partial mole
D. Decreased level of T3 and T4 and C. Hydatidiform mole
increased level of TSH T D. Teratocarcinoma
E. Increased level of free T3 and T4 and E. Benign cystic teratoma T
decreased level of TSH
259 - Which of the following genetic
256 - A 25 years female comes to the mutations are commonly seen in breast
clinician with complains of swelling in the cancer is :
cervical region. Histopathological
examination reveals lymph node A. RB gene
metastasized by papillary carcinoma of B. BRCA - 1 T
thyroid. Which of the following is not a C. P53
feature of papillary carcinoma of thyroid. D. BCL - 2
E. PTEN
A. Pseudo inclusion
B. Psamomma bodies 260 - A patient presents with
C. Orphan annie eye nuclei hypertension, hematuria, flank pain and
D. Papillary processes with fibrovascular nephrolithiasis. Examination of kidney
core reveals many cysts. A common -
E. Papillary processes with fibrovascular complication his disease is :
core ( pseudopapillae ) T
A. Berry aneurysms T
257 - A 60 years old male complains of B. Pneumonia
retension of urine. On ultrasound C. Haemorrhages
examination shows enlargement of D. Hypertension
prostate. Serum PSA level is 5 ng/ml. E. None of the above
What is the most common clinical
condition in this patient :

A. Urethritis
B. Acute prostatitis
C. Chronic prostatitis
D. Adenocarcinoma prostate
E. Benign nodular hyperplasia T
261 - 50 years female had fever and flank E. Truncus arteriosus
pain for past 2 days urine analysis shows
no protein, glucose on ketones. 265 - Which ONE of the following is
Microscopic examination of urine shows characteristically found in acute diffuse
numerous polymorphs and occasional proliferative glomerulonephritis :
WBC cast. which of the following
organism is most likely to be found in A. Endothelial and mesangial cell
urine culture : hyperplasia.
B. Fibrinoid necrosis of glomerular
A. E. Coli T capillaries
B. Mycobacterium tuberculosis C. Focal sclerosis of glomerular tufts
C. Group A streptococci D. Hyalinization of arcuate arteries
E. Severe basement membrane
thickening
262 - All are clinical presentation of
266 - Rapidly progressive
eclampsia except :
glomerulonephritis is best characterized
morphologically by which ONE of the
A. Hypertension
following :
B. Proteinurea
C. Edema
A. Basement membrane thickening
D. Anemia T
B. Crescent formation T
E. Convulsions
C. Fibrinoid necrosis of the afferent
arteriole
263 - Which ONE of the following is least
D. Interstitial fibrosis
likely to be found in a child dying of acute
E. Mesangial cell proliferation
rheumatic fever :
267 - Which one of the following is least
A. Aschoff bodies.
likely to lead to metastases by the blood
B. 'Bread and butter' pericarditis T
stream :
C. History of recent sore throat
D. Large crumbling vegetations on the
A. Follicular carcinoma of thyroid
mitral valve
B. Giant cell carcinoma of thyroid
E. Raised anti-streptolysin O titre (ASO)
C. Medullary carcinoma of thyroid
titre
D. Papillary carcinoma of thyroid
E. Small cell anaplastic carcinoma of
264 - Which ONE of the following is an
thyroid
example of acyanotic congenital heart
disease :

A. Anomalous venous drainage

B. Coarctation of the aorta T
C. Fallot's tetralogy
D. Tricuspid atresia
268 - Which ONE of the following is not
true of prostatic carcinoma :
A. Acid phosphatase level raised in serum
B. Alkaline phosphatase detected in
tumour cells
C. Metastases are osteoplastic
D. Microacinar adenocarcinoma T
E. Usually arises at periphery of the gland
269 - In a patient with mixed germ cell
tumor of the testis, which serum
marker/markers are best used to monitor
response to chemotherapy :
A. AFP and HCG
B. LDH and CEA
C. CEA and AFP T
D. Ca-125
E. CA-19-9
270 - A 25-year-old male presents with a
rapidly enlarging painless testicular
mass. Serum HCG is markedly raised. A
diagnosis of mixed germ cell tumor is
made on Histopathology of the
orchidectomy specimen. Which
component of the mixed tumor is most
responsible for the rise in HCG :
A. Embryonal carcinoma
B. Yolk sac tumor
C. Teratoma
D. Choriocarcinoma T
E. Seminoma
271 - A 28-year-old male presents with a
rapidly enlarging painless testicular
mass. Serum alpha feto protein is
markedly raised. A diagnosis of mixed
germ cell tumor is made on
Histopathology of the orchidectomy
specimen. Which component of the
mixed tumor is most responsible for the
rise in alpha feto protein :
A. Embryonal carcinoma T
B. Yolk sac tumor
C. Teratoma
D. Choriocarcinoma
E. Seminoma
272 - A 55-year-old male presents with
low back pain, dysuria and suprapubic
discomfort. Expressed prostatic
secretions contain 15 leukocytes/HPF.
Bacterial cultures are negative. What is
the diagnosis :
A. Granulomatous prostatitis
B. Acute prostatitis
C. Chronic bacterial prostatitis
D. Chronic abacterial prostatitis
E. Nodular hyperplasia T
273 - For predicting prognosis of prostatic
adenocarcinoma, what is the most
important factor besides tumor stage :
A. Perineural invasion
B. Comorbid conditions
C. Tumor grade
D. Immune status
E. Serum PSA levels T
274 - A 45-year-old female having history
of multiple sexual partners is diagnosed
as Squamous cell carcinoma of cervix.
Genetic material of which virus is most
likely to be detected in the tumor :
A. HPV 16 T
B. HPV 6
C. EBV
D. HSV type I
E. HSV type II
275 - A cystic mass removed from the
right ovary of a 28-year-old female
consists of a cyst wall lined by mature
stratified Squamous epithelium with skin
appendages. Mature gut and bronchial
epithelium, cartilage and thyroid tissue
are also present. What malignant
transformation is this tumor most likely
to undergo :
A. Immature teratoma T
B. Squamous cell carcinoma
C. Thyroid follicular carcinoma
D Adenocarcinoma
E. Chondrosarcoma
276 - A 28-year-old female presents with
dysmenorrhea, pelvic pain and irregular
vaginal bleeding. Ultrasound
examination reveals a partly cystic right
adnexal mass. Cystectomy specimen is
filled with thick chocolate colored fluid
and histologic sections reveal a cyst wall
lined showing marked hemorrhage, with
endometrial glands and stroma along
with hemosiderin-laden macrophages.
What is the diagnosis :
A. Mucinous cystadenoma
B. Serous cyst adenoma
C. Endometriotic cyst T
D. Hemangioma
E. Endometrial carcinoma
277 - A 22-year-old female is diagnosed
with a malignant germ cell tumor of the
ovary that is metastatic to liver, lungs
and bone at the time of diagnosis. What
is this tumor most likely to be :
A. Yolk sac tumor
B. Dysgerminoma T
C. Choriocarcinoma
D. Embryonal carcinoma
E. Teratoma
278 - A cystic mass removed from the
right ovary of a 28-year-old female
consists of a cyst wall lined by mature
stratified Squamous epithelium with skin
appendages. Mature gut and bronchial
epithelium and cartilage are also present.
What is the expected karyotype of this
tumor :
A. 46XX T
B. 46XY
C. 45Y
D. 47XXY
E. 45X
279 - A 58-year-old nulliparous woman
with history of functional menstrual
abnormalities is most likely to develop:
A. Endometroid endometrial carcinoma T
B. Cervical Squamous cell carcinoma
C. Cervical adenocarcinoma
D. Ovarian cystadenocarcinoma
E. Endometrial stromal tumor
280 - Struma ovarii is a
monodermalteratoma composed of :
A. Bone
B. Cartilage
C. Thyroid tissue T
D. Skin and appendages
E. Skeletal muscle
281 - A 45-year-old female presents with
massive abdominal distension causing
respiratory distress. An emergency
laparotomy reveals massive Mucinous
ascites and adhesions with a large left
ovarian tumor, which is later, reported as
a borderline Mucinous neoplasm. What is
this condition known as :
A. Meigs syndrome T
B. Pseudomyxomaperitonei
C. Krukenbergtumor
D. Carcinomatosis
E. Mullerian Mucinous cystadenoma
282 - A 32-year-old female presents with
a painless, irregular firm to hard mass in
her right breast. She has history of
trauma to the breast. Excised mass
consists of foci of necrotic fat cells
surrounded by macrophages and intense
inflammatory reaction. What is the
diagnosis :
A. Acute mastitis
B. Invasive carcinoma
C. Fat necrosis
D. Fibroadenoma
E. Lipoma T
283 - Which breast lesion carries the
greatest risk of developing into an
invasive carcinoma :
A. Fibroadenoma
B. Papilloma
C. Atypical ductal hyperplasia
D. Low grade DCIS
E. High grade DCIS T
284 - What is the commonest causative
organism for acute mastitis :
A. Streptococcus aureus
B. Staphylococcus aureus T
C. E coli
D. Pseudomonas
E. Candida albicans
285 - A 30-year-old female smoker
presents with a painful subareolar mass
in her left breast. On examination the
nipple is found to be inverted. Histology
of excised lesion shows squamous
metaplasia of lactiferous duct with
abundant keratin trapped in the lumen.
Adjacent tissue shows chronic
inflammation. What is the diagnosis :
A. Paget’s disease
B. Acute mastitis
C. Fat necrosis
D. Periductal mastitis
E. Mammary duct ectasia
286 - Buerger disease is associated with :
☆ Cigarette smoking
287 - After a mastectomy with axillary
clearance for breast cancer 1 year ago, a
47 year old woman has developed
persistent swelling and puffiness in the
left arm. The arm is not painful or
discolored. She developed cellulitis in left
arm 3 weeks ago. Best term describe
these finding is :
A. Thrombophlebitis
B. Tumor embolization
C. Lymphedema T
288 - The Renal cell carcinoma :
A. Most common in children
B. Majority of cases are familial
C. Chromphobe carcinoma has an
excellent prognosis
289 - Which one of are the key processes
in the development of atherosclerosis :
☆Intimal thickening & lipid accumulation
290 - A 40 years old female consults a
doctor, complaining of tachycardia
palpitation and protrusion of eye ball.
Laboratory investigations reveals
increased level of free T3 and free T4. The
most likely diagnosis is :
☆ Graves Disease
291 - A 30 year female clinicaly presents
with hard irregular right breast lump.
Which one of the following is not
associated with increased risk of breast
cancer :
A. Breast feeding T
B. BRCA - 2 gene carrier
C. Family history of breast cancer
D. Biopsy results that show ductal
carcinoma in situ
E. Biopsy results that show atypical
lobular hyperplasia
292 - Ovarian tumor most likely have
virilizing effects :
☆Sertolileyding cell tumor
293 - A 60 year old developed hematuria
since one week. A cystoscopy is
performed and a 5 cm exophytic mass is
seen in bladder. A biopsy of this mass is
performed and microscopic examination
papillary carcinoma with invasion in
muscularispropria. CT scan reveals
metastasis in external and common iliac
lymph nodes and no distant metastasis.
Tumor stage according to AJCC is :
A. T2 N3 M0 T
B. T2 N2 M0
C. T1 N3 M0
D. T1 N2 M0
E. T1 N1 M0
294 - Fructose present in semen, secreted
by which of the following organs of male
reproductive system :
☆ seminal vesicles
295 - Precise cause of cryptorchoidism is
most likely :
☆ Idiopathic
296 - Surgical repositioning of testes in
case of cryptorchoidism is preferably
indicated by age of :
☆ 5 - 12 months
297 - A 65 years old man presents with a
5 months history of a scrotal mass. Which
of the following is the most likely
diagnosis :
☆Spermatocytic Seminoma
298 - Which of the following tumor
marker for germ cell tumors of testicle is
to assess tumor burden and provide an
independent prognostic marker :
☆ LDH
299 - The risk of testicular tumor is higher
in patient with :
☆Moris syndrome
300 - The commonest causative
organisms of epidedymitis in children is
most likely :
☆ Gram negative bacilli
301 - The most important diagnostic
microscopic features in carcinoma of
prostate is :
☆ Invasion of perineural lymphatics
302 - Chromosomal study of which of the
following cancer shows hypermethylation
of GSTP1 in > 90% tumor cells :
☆ Carcinoma of prostate
303 - Chronic bacterial prostatis most
likely caused by :
☆ E. Coli, pseudomonas, staph aureus,
enterobacter
304 - A 20 years old woman presents for
question regarding fertility. Laboratory
studies previously identified a 21 -
hydroxylase deficiency and adrenogenital
syndrome. Physical examination reveals
virilization of vulva and enlarged clitoris.
What is the most likely karyotype of this
patient :
A. 46 XX T
B. 46 XY
C. 45 XO
D. 47 XXX
E. 47 XXY
305 - Longer disease free survival and
overall survival are expected in women
whose breast cancer show a high degree
or level of :
☆Estrogen receptors
306 - A 30 years old man presents with
acute and chronic inflammation of his
glans penis. Which of the following is the
most likely complication of chronic
balanitis in this patient :
☆Phimosis
307 - Biopsy of endocervicalpolypoid
mass in a 33 year old woman on oral
contraceptive who presented with
abnormal bleeding is most likely to show
:
☆Microglandular hyperplasia
308 - Which of the following epithelia is
most resistant to gonorrhea :
☆ Vagina of sexually mature women
309 - Which of the following risk factor 310 - Acute left ventricular failure is
correlates best with development of accompanied by :
cervical intraepithelial neoplasia :
☆ Pulmonary oedema
☆ Coitus at early age and multiple sexual
partners 311 - MichaelisGutmann concretions are
present with in macrophages in urinary
bladder in :
☆ Malakoplakia
312 - At what blood pressure, you regard a patient is hypertensive :

A. Sustained diastolic > 89 mm of Hg or sustained systolic > 139 mm T

B. Sustained diastolic > 95 mm of Hg or sustained systolic > 145 mm
C. Sustained diastolic > 85 mm of Hg or sustained systolic > 135 mm
D. Sustained diastolic > 100 mm of Hg or > sustained systolic > 150 mm
E. Sustained diastolic > 105 mm of Hg or sustained systolic 155 mm