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    era jane asperga
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    Primary reference materials are directly weighed or measured to produce solutions of exactly known concentration, have 99.98% purity, are non-hygroscopic, and come with a certificate of analysis for each lot. Secondary reference materials cannot be prepared by weighing and dissolving a known amount, and are usually determined by analyzing an aliquot using an acceptable reference method. Certified standard reference materials and certified reference materials from NIST and IRMM respectively are characterized for certain chemical or physical properties and issued with certificates for use in clinical and molecular laboratories.

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    Primary reference materials are directly weighed or measured to produce solutions of exactly known concentration, have 99.98% purity, are non-hygroscopic, and come with a certificate of analysis for each lot. Secondary reference materials cannot be prepared by weighing and dissolving a known amount, and are usually determined by analyzing an aliquot using an acceptable reference method. Certified standard reference materials and certified reference materials from NIST and IRMM respectively are characterized for certain chemical or physical properties and issued with certificates for use in clinical and molecular laboratories.

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    4 views1 page

    Reference Material

    Uploaded by

    era jane asperga
    Primary reference materials are directly weighed or measured to produce solutions of exactly known concentration, have 99.98% purity, are non-hygroscopic, and come with a certificate of analysis for each lot. Secondary reference materials cannot be prepared by weighing and dissolving a known amount, and are usually determined by analyzing an aliquot using an acceptable reference method. Certified standard reference materials and certified reference materials from NIST and IRMM respectively are characterized for certain chemical or physical properties and issued with certificates for use in clinical and molecular laboratories.

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    © All Rights Reserved
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    TOPIC: REFERENCE MATERIAL

    Type Preparation Characteristics


    Primary  Directly weighed or measured to produce  99.98% Purity
    a solution with exactly known  Non-hygroscopic
    concentration  Has a certificate of analysis for each
    lot.

    Secondary  Cannot be prepared by weighing a solute  Calibrated using a primary standard


    and dissolving a known amount into a
    volume of solutions

     Usually determined by analysis of aliquot


    of the solution by an acceptable reference
    method

    Certified
    Standard Reference  For clinical and molecular laboratories  Characterized for certain chemical or
    Materials (SRMs) physical properties
     Available from National Institute of
    Standards and Technology (NIST)  Issued with certificates
    Certified Reference  For clinical and molecular lab
    Material (CRMs)
     Available from the Institute for Reference
    Materials and Measurements (IRMM)

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