Neuroscience We're pushing boundaries of scientific understanding to achieve clinical advancements and solve some of the greatest challenges in neuroscience today— to preserve what makes us who we are. Challenge Impacting millions There are hundreds of nervous system disorders impacting millions of people around the world, Almost everyone knows a personFocus affected by a neurological condition, which can have a profound impact on day-to-day life. Our innovative medicines and diagnostic tests continue to push the boundaries of scientific understanding and help patients worldwide. A highly complex field Nervous system disorders can create barriers that impact our ability to engage, to move, to remember and over time, can change or take away the unique qualities that make us who we are. Or in the case of disorders affecting children, who we may become. Over time, the physical, mental and emotional burden can be overwhelming. However, people with nervous system disorders face their challenges with bravery and determination Following the science We are driven by the idea that the rigorous pursuit of ground- breaking science can transform the lives of people facing serious and life-threatening diseases. We are collaborating with academia, scientists, industry partners and clinical trial participants, and are following the science to improve the lives of patients. With their support, we are collectively responsible for major therapeutic advances for some of the world’s most difficult treat diseases in fields Bridging the gap Neurological conditions have been the most complex to understand and treat, and the impact of these conditions is creating new challenges for health systems, economies, patients, and families across the globe.Data generation is essential to provide a clear and measurable understanding of the global and local burden of disease. Read more about how we are working with our partners to leverage the power of data to drive active change and tackle societal burden head on Hope for the future Neuroscience is a cornerstone of our future, but we cannot do it alone. Together, ith our partners, we will continue to push the boundaries of scientific understanding to achieve clinical advancements and solve some of the greatest challenges in neuroscience today. Our hope is to create a tomorrow where neurological disorders no longer limit human potential-to preserve what makes us who we are. With their support, we are collectively responsible for major therapeutic advances for some of the world’s most difficult-t. treat diseases in fieldsRoche in Neuroscience and Rare Disease At Roche, our hope is to create a tomorrow where nervous system disorders no longer limit human potential - to preserve what makes us who we are. Diagnostics for central nervous system diseases We are investing heavily into finding innovative strategies to help protect and preserve people's mental health, quality of life, and own identity. Learn more Cases in detailMultiple Sclerosis > We're committed to advancing the clinical understanding of underlying disease activity and progression for the millions of people living with multiple sclerosis (MS) worldwide: \« i : ’ Duchenne muscular > dystrophy Together with Sarepta Therapeutics, Roche is partnering with the Duchenne muscular dystrophy (DMD) community to change the way Duchenne is treated. Spinal Muscular Atrophy > (SMA) We have been working in partnership with the SMA community to transform outcomes for a broad range of people living with the rare, neurological condition. PeFeTe* Neuromyelitis optica > spectrum disorder (NMOSD) Through medical innovation and partnerships, we are providing new options to people living with neuromyelitis optica spectrum disorder (NMOSD) to help them retain as much independence as possibleAlzheimer's disease > Rising to the global challenge of Alzheimer's disease through innovation and collaboration. Stories of Neuroscience mi The past 5 years of B-cell therapy in multiple sclerosis April 24, 2023 Rare disease > Working together to build a better world for people with rare diseases. See more stories > al Understanding the societal and economic impact of neurological conditions globally October 28, 2022Portraying multiple sclerosis community stories October 24, 2022More focus areas View all focus areas > M..~ el Cardiometabolic diseases > Diabetes > 1/3 > Discover more Innovation Partnering > At Roche Partnering, we are passionate about science: yours and ours. Through partnerships, we hope that together we can build a better future with medicines that make a real difference to patients. Innovation Clinical trials > Clinical trials are essential to determine whether new drugs or diagnostics are safe and effective when used to diagnose or treat people.