Professional Documents
Culture Documents
Patrick B. Wright, M.D., Jeffrey E. Budoff, M.D., Ming Long Yeh, Ph.D., Zachary S. Kelm,
and Zong-Ping Luo, Ph.D.
Purpose: The purpose of this study was to determine the mechanical properties of undamaged and
damaged sutures in metal and bioabsorbable suture anchors. Methods: Undamaged and damaged
FiberWire (Arthrex, Naples, FL), Tevdek (Deknatel, Mansfield, MA), and PDS (Ethicon, Somerville,
NJ) sutures were tested by a single pull to failure while being pulled parallel to the axis of either a
metal or bioabsorbable suture anchor. Sutures were damaged by use of a razor blade incorporated into
a custom-designed jig. The friction of the sutures through the anchor eyelets was also tested. Results:
For both anchor types, FiberWire was the strongest suture studied. Undamaged PDS had a signifi-
cantly greater load to failure than Tevdek. Although all sutures lost significant strength when
damaged, PDS lost the most, with damaged PDS becoming significantly weaker than damaged
Tevdek. Damaged FiberWire was significantly stronger in metal anchors compared with bioabsorb-
able anchors, with failure of the bioabsorbable suture eyelet preventing testing of undamaged
FiberWire. Neither undamaged nor damaged PDS or Tevdek had a significant difference in strength
between metal and bioabsorbable anchors. However, in metal anchors the mechanical properties of
undamaged Tevdek were inferior to those of the other undamaged sutures tested. For undamaged or
damaged sutures through either anchor type, PDS suture had the highest coefficient of friction,
significantly higher than FiberWire and Tevdek. All sutures, undamaged or damaged, had signifi-
cantly less friction in bioabsorbable anchors compared with metal anchors. Conclusions: The
FiberWire-anchor construct is significantly weaker when bioabsorbable anchors are used instead of
metal anchors. For Tevdek and PDS sutures, the anchor type does not affect the strength of the
construct, as the suture is the limiting factor. When used with suture anchors, PDS has the most
friction of the sutures tested, potentially leading to suture damage, which disproportionately weakens
PDS compared with the other sutures tested. For both undamaged and damaged sutures, bioabsorb-
able anchors lead to less friction than do metal anchors, which may lessen suture damage in vivo.
Clinical Relevance: The mechanical properties of damaged suture are important to all surgeons who
use suture arthroscopically. Key Words: Suture—Damage—Biomechanics—Suture anchor.
Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 23, No 6 (June), 2007: pp 655-661 655
656 P. B. WRIGHT ET AL.
METHODS
Three types of suture were tested: Tevdek (Deknatel,
Mansfield, MA), FiberWire (Arthrex, Naples, FL),
and PDS (Ethicon, Somerville, NJ). The anchors used
were the metal Arthrex 5.0-mm Corkscrew and the
bioabsorbable Arthrex 5.0-mm Bio-Corkscrew. Simi-
lar to other studies,2,3 preliminary testing did not show
differences in failure behavior between dry and wet
suture material. Therefore, to be consistent with pre-
vious studies,1-5 testing of all sutures was performed
dry at room temperature. The manufacturers have FIGURE 1. Diagram of suture anchor U test. (Reprinted with
indicated that the difference between room and body permission.3)
temperature would be too small to make a significant
difference in the biomechanical properties of the su-
tures. it, toward the center of the eyelet. All tests were
Twenty-four sutures of each type were used for the performed at a displacement rate of 60 mm/min on an
load-to-failure/failure stress test; 12 were used with MTS 858 Bionix machine (MTS, Eden Prairie, MN).
metal anchors and 12 with bioabsorbable anchors. The anchor was rotated 180° after each test to reduce
Each of these groups was subdivided into 6 sutures to any error resulting from manufacturing variance. Any
be tested undamaged and 6 to be tested damaged. To damaged anchors were discarded. Any test that re-
simulate potential damage incurred at the anchor site sulted in anchor failure was discarded so that only data
during surgical procedures, sutures were then dam- where suture strength was the limiting factor were
aged by cutting approximately 33% of their width analyzed. The load to failure (LTF) was recorded as
with a razor blade placed in a custom jig. This per- the maximal load.
centage of suture damage was chosen after a pilot Technically, the term ultimate tensile stress is only
study so that the newer polyethylene suture used for tests that solely measure material properties,
(FiberWire) could be tested in bioabsorbable anchors such as the straight-line pull test, and this term is
without routinely destroying the anchor’s eyelet. The technically incorrect for a test involving an interaction
goal was to minimize anchor breakage as a confound- with another object (i.e., a suture anchor). Therefore,
ing factor. The total width of the suture and the cut for the tensile failure test, we use the term failure
depth were measured by use of a light microscope stress (FS) to denote the material property of the
attached to an electric micrometer to determine total suture, as well as its interaction with the suture eyelet.
remaining cross-sectional area. FS was calculated as LTF divided by cross-sectional
For all tests, the suture anchors were clamped be- area, which had the decreased area corrected for in
tween the flanges of a vise. The suture was passed damaged sutures. Because the purpose of this study is
through the suture anchor eyelet. The free ends of the to evaluate the biomechanical properties of suture and
suture were wound around a metallic hook to avoid not the anchor, only trials that failed because of suture
weakening the suture with knot tying. For single-pull, breakage were included in the analysis.
load-to-failure testing, the load was applied to both The friction of damaged and undamaged sutures
free ends of the suture parallel to the axis of the anchor was measured while being pulled through a suture
insertion, as in the U test2,3 (Fig 1). For tests involving anchor eyelet at a 45° angle, a different angle than was
damaged suture, the damaged area was placed against used for the LTF suture anchor test. An additional 24
the superior rim of the anchor loop, facing away from sutures of each type were used for the friction test; 12
SUTURES AND METAL AND BIOABSORBABLE ANCHORS 657
RESULTS
Suture Characteristics
Despite the fact that all sutures tested were No. 2
sutures, their cross-sectional areas varied. The cross-
FIGURE 2. Photograph of suture anchor U test. The body of the sectional area of uncut Tevdek was 0.26 ⫾ 0.03 mm2,
suture anchor is securely clamped between the flanges of a vise that of uncut PDS was 0.29 ⫾ 0.02 mm2, and that of
in such a way as to avoid damaging the anchor or altering the uncut FiberWire was 0.39 ⫾ 0.12 mm2, significantly
eyelet.
greater than both Tevdek and PDS (P ⬍ .05). The
percentage of suture cut for each test was very repro-
ducible within 3.1%, ranging from 33.50% to 36.60%.
were used with metal anchors and 12 with bioabsorb-
able anchors. Each of these groups was subdivided
into 6 sutures to be tested undamaged and 6 to be
tested damaged. The bodies of the suture anchors were
securely clamped between the flanges of a vise in such
a way as to avoid damaging the anchor or altering the
eyelet (Fig 2). The technique has been previously
described.2,3 The sutures were attached to an MTS
machine’s cross-head by use of Capstan grips, with a
passive load cell (range, 0 to 1,000 N). All tests were
performed at a displacement rate of 60 mm/min. One
suture branch was passed through the anchor eyelet
and pulled straight in line with the suture anchor axis
by an MTS machine, and the force at failure (Fa) was
recorded. The resulting force on the second suture
branch with an angle of 45° to the suture anchor axis
(Fp) was measured simultaneously by use of a second
electronic load cell (Fig 3).
For damaged sutures, the cut area was placed on the
suture branch held at 45° from the suture anchor axis,
1 cm from the anchor eyelet, facing toward the supe-
rior rim of the anchor loop, to ensure that the damaged
area would pass against the anchor loop. Loads were
FIGURE 3. Diagram of friction test. The testing machine pulls one
electronically transformed to an analog voltage de- branch (Fa, active) while the tensile load on the second branch (Fp,
vice, processed by an analog/digital converter, and passive) is recorded simultaneously. (Reprinted with permission.3)
658 P. B. WRIGHT ET AL.
TABLE 1. LTF and FS of Cut and Uncut Tevdek, PDS, and FiberWire in Metal and Bioabsorbable Anchors
Tevdek PDS FiberWire Significance
LTF (N)
Undamaged suture
Metal anchor 202.80 ⫾ 7.70 248.37 ⫾ 16.00 365.88 ⫾ 15.57 FW ⬎ PDS ⬎ Tevdek
Bioabsorbable anchor 200.68 ⫾ 17.39 240.72 ⫾ 21.24 NA PDS ⬎ Tevdek
Damaged suture
Metal anchor 135.02 ⫾ 10.67 55.08 ⫾ 2.77 262.88 ⫾ 30.35 FW ⬎ Tevdek ⬎ PDS
Bioabsorbable anchor 138.41 ⫾ 22.54 53.45 ⫾ 5.16 218.63 ⫾ 8.93 FW ⬎ Tevdek ⬎ PDS
FS (MPa)
Undamaged suture
Metal anchor 833.94 ⫾ 21.65 1,110.50 ⫾ 193.26 1,033.08 ⫾ 109.83 FW ⫽ PDS ⬎ Tevdek
Bioabsorbable anchor 916.57 ⫾ 150.25 1,028.36 ⫾ 223.21 NA PDS ⫽ Tevdek
Damaged suture
Metal anchor 837.46 ⫾ 57.45 376.04 ⫾ 100.13 1,208.87 ⫾ 164.87 FW ⬎ Tevdek ⬎ PDS
Bioabsorbable anchor 1,011.94 ⫾ 262.43 359.44 ⫾ 100.37 839.27 ⫾ 118.08 FW ⫽ Tevdek ⬎ PDS
NOTE. A “greater than” sign indicates significantly greater, whereas an “equals” sign indicates that there is no significant difference
between the two sutures’ values.
Abbreviation: NA, not applicable.
SUTURES AND METAL AND BIOABSORBABLE ANCHORS 659
same relationship holds true, because the bioabsorb- icant change in friction when damaged (P ⫽ .17).
able anchor’s eyelet was strong enough to allow Tevdek had a significant decrease in friction when
testing of 6 of 8 damaged FiberWire sutures but no damaged (P ⫽ .014). When being pulled through a
undamaged FiberWire sutures. bioabsorbable anchor, no suture had a significant
For metal anchors, there was no significant differ- change in friction when damaged (P ⫽ .52).
ence in FS for FiberWire and Tevdek between undam-
aged and damaged sutures (P ⬎ .05). For bioabsorb-
able anchors, Tevdek had no significant change in FS DISCUSSION
when damaged (P ⬎ .05). Damaged PDS had a sig- In this study we tested the strength (LTF and FS)
nificantly lower FS compared with undamaged PDS and friction of undamaged and damaged sutures in
for both metal (P ⫽ .0001) and bioabsorbable anchors metal and bioabsorbable anchors. For metal anchors,
(P ⫽ .002). failure occurred exclusively by suture breakage. Dam-
Friction Testing aged FiberWire was found to be stronger (higher LTF
and FS) in metal anchors than in bioabsorbable an-
The results of friction through the anchor are sum- chors because in bioabsorbable anchors, FiberWire’s
marized in Table 2. For undamaged sutures through high LTF shifts the failure mechanism from suture
either a metal or bioabsorbable anchor, PDS suture failure to eyelet failure. This is similar to the findings
had the highest coefficient of friction, significantly of Bardana et al.,1 who reported that constructs using
higher than the other sutures (P ⫽ .0003). There was bioabsorbable anchors had a mixture of suture and
no significant difference in friction between undam- anchor eyelet failures. The metal Corkscrew anchor
aged Tevdek and FiberWire through either type of and its eyelet are cast from the same piece of metal,
anchor (P ⫽ .44). leading to significant anchor eyelet strength. The bio-
For damaged sutures through either anchor, PDS absorbable anchor’s eyelet is made of No. 3 Tevdek
suture again had the highest coefficient of friction, suture, which is molded into the anchor’s polymer. It
significantly greater than the other sutures (P ⫽ .0001 is therefore significantly weaker than the metal an-
for metal anchors and P ⫽ .0003 for bioabsorbable chor’s eyelet.
anchors). Damaged FiberWire had significantly Although all tests that resulted in anchor damage
greater friction than damaged Tevdek with metal an- were not used for the purposes of the results, the fact
chors (P ⫽ .004), but there was no significant differ- that 2 of 8 bioabsorbable anchor eyelets were de-
ence between these 2 sutures with bioabsorbable an- stroyed by damaged FiberWire lowers the mean
chors. strength of the construct by invalidating those trials
All sutures, damaged and undamaged, had signifi- in which the strength of the damaged FiberWire
cantly less friction in bioabsorbable anchors compared was above that of the bioabsorbable anchor’s eye-
with metal anchors (P ⫽ .028 for undamaged suture, lets. Given that the tensile strength of undamaged
P ⫽ .0016 for damaged FiberWire and PDS, and P ⫽ FiberWire was higher than that of the bioabsorbable
.05 for damaged Tevdek). When being pulled through anchor’s eyelet, the bioabsorbable anchors themselves
a metal anchor, FiberWire had a significant increase in limited the strength of the FiberWire-anchor con-
friction when damaged (P ⫽ .03). PDS had no signif- struct, and it was not possible to test the mechanical
TABLE 2. Friction of Uncut and Cut Tevdek, PDS, and FiberWire in Metal and Bioabsorbable Anchors
Fa/Fp
Uncut suture
Metal anchor 0.32 ⫾ 0.01 0.37 ⫾ 0.02 0.31 ⫾ 0.02 PDS ⬎ FW ⫽ Tevdek
Bioabsorbable anchor 0.29 ⫾ 0.01 0.33 ⫾ 0.01 0.29 ⫾ 0.01 PDS ⬎ FW ⫽ Tevdek
Cut suture
Metal anchor 0.29 ⫾ 0.01 0.39 ⫾ 0.01 0.33 ⫾ 0.02 PDS ⬎ FW ⬎ Tevdek
Bioabsorbable anchor 0.29 ⫾ 0.01 0.34 ⫾ 0.01 0.29 ⫾ 0.02 PDS ⬎ FW ⫽ Tevdek
NOTE. A “greater than” sign indicates significantly greater, whereas an “equals” sign indicates that there is no significant difference
between the 2 sutures’ values.
660 P. B. WRIGHT ET AL.
properties of uncut FiberWire in this setting. For decreased so greatly when damaged. Damaging a
Tevdek and PDS, the sutures themselves were the braided suture does not increase the stress concentra-
limiting factor of the suture– bioabsorbable anchor tion as much because there is no leading edge, given
construct. that there are still intact bundles on the edge of the cut.
Undamaged FiberWire had a significantly higher PDS was one of the first sutures used for arthro-
LTF than PDS with both metal and bioabsorbable scopic shoulder reconstructions.6-8 PDS is an absorb-
anchors, and both FiberWire and PDS had a signifi- able monofilament suture composed of the polyester
cantly higher LTF than Tevdek. With metal anchors, poly(p-dioxanone). Surgeons then began using nonab-
there was no significant difference between the FS for sorbable sutures, such as Tevdek. Tevdek is a braided
FiberWire and PDS, implying that with its greater polyester suture impregnated with polytetrafluoroeth-
cross-sectional area adjusted for, the undamaged com- ylene. Newer hybrid sutures have been developed and
posite FiberWire material had no increased strength are now popular for shoulder reconstructions.9,10
compared with undamaged PDS. For metal anchors, FiberWire has an ultrahigh–molecular weight polyeth-
both undamaged FiberWire and PDS had a signifi- ylene core with a braided polyethylene terephthalate
cantly higher FS than undamaged Tevdek. For bioab- polyester ultrahigh–molecular weight polyethylene
sorbable anchors, there was no significant difference jacket.
in FS between undamaged PDS and Tevdek. This sug- Under cyclic loading, sutures may abrade on their
gests that when interacting with a metal eyelet, Tevdek anchor’s eyelet. The friction created depends on the
has inferior mechanical (structural and material) proper- design of the anchor eyelet, the roughness of the
ties compared with both PDS and FiberWire sutures. matching surfaces, and the arc of contact between
Undamaged PDS may have a significantly greater the suture material and the anchor eyelet. In the study
FS than Tevdek through metal anchors, but not of Bardana et al.,1 sutures performed significantly
through bioabsorbable anchors, because Tevdek may better when cycled at an angle of pull in line with the
be more sensitive to the sharper edges of the metal anchors. To compare metal and bioabsorbable an-
eyelet. As noted in a previous study,2 PDS lost sig- chors, we chose to use these optimum conditions. We
nificantly more strength (LTF and FS) when damaged noted that, for all undamaged and damaged sutures,
than did the other sutures. For both anchor types, friction was less in bioabsorbable anchors compared
damaged PDS had a significantly lower strength (LTF with metal anchors. In addition, when being pulled
and FS) than did Tevdek and FiberWire. For metal through a bioabsorbable anchor, no suture had a sig-
anchors, damaged FiberWire had a greater strength nificant change in friction when damaged. This agrees
(LTF and FS) than did Tevdek. For bioabsorbable with the findings of previous authors who noted that
anchors, although damaged FiberWire had a higher metallic anchors tend to have rough eyelet surfaces
LTF than damaged Tevdek, there was no significant with sharp edges, which may damage sutures, leading
difference between their FS. This implies that, with its to failure,1,5 whereas the eyelets of bioabsorbable im-
greater cross-sectional area accounted for, the dam- plants have smoother edges, decreasing suture abra-
aged composite FiberWire material did not have sion under cyclic loading.11
greater strength than cut Tevdek. It is possible that PDS (undamaged or damaged, in either metal or
Tevdek may be relatively stronger in bioabsorbable bioabsorbable anchors) had significantly more friction
anchors because of the lack of sharp edges on their than the other sutures tested, which may predispose it
eyelets. to damage, which then weakens it significantly. In
All sutures lost significant LTF when damaged. metal anchors FiberWire’s friction increased signifi-
Neither FiberWire nor Tevdek had a significant loss of cantly when damaged and was significantly greater
FS when damaged, implying that for these sutures, FS than cut Tevdek. This may be due to the fact that
is, in fact, truly a material property. However, PDS did FiberWire is stiffer than Tevdek,2 allowing its cut
have a significant loss of FS when damaged. This may edge to catch the metal eyelet with greater force.
be because of the fact that PDS is a monofilament and As is the case for all in vitro studies, ours has
not a braided suture (made up of bundles of individual several limitations. The amount of damage studied
fibers), such as FiberWire and Tevdek. When mono- here (33% of suture diameter) may over- or under-
filament suture is damaged, there is an increase of represent the damage present in common clinical sit-
stress concentration at the leading edge of the cut, uations, and a razor blade may not exactly simulate
which greatly decreases the force required to cause damage that occurs in vivo. However, it is difficult to
failure. This may be why both the LTF and FS of PDS classify the damage that occurs to a suture in the
SUTURES AND METAL AND BIOABSORBABLE ANCHORS 661