MCQS IN MINOR BLOOD GROUPS

NAME : SALMAN SHAH

1) Which of the following minor blood group cause sever HDN and transfusion reaction.
A) Kell blood group
B) Duffy blood group
C) Kid blood group
D) Rh blood group

2) Which minor blood group show resistance to malarial parasite.

A) Duffy blood group
B) Kid blood group
C) Kell blood group
D) ABO blood group

3) Molecular weight of Kell antigen are _________.

A) 93k
B) 45k
C) 65k
D) 33k

4) Kell gene are located on _______ chromosome.

A) 9
B) 8
C) 10
D) 7

5) All minor blood groups antibodies are belongs to which type of antibody .
A) IgG type 1
B) IgG type 2
C) IgM
D) IgA

6) How many time kell antigens folded cross cell membrane.

A) 10
B) 7
C) 4
D) 11

7) Duffy gene are located on ________ chromosomes.

A) 7
 B) 8
C) 18
D) 1

8) DARC ( Duffy gene) which consists of ______ exon and ____ intron.
A) 2,1
B) 3,1
C) 1,2
D) 4,3

9) Kid gene are located on ______ chromosome.

A) 1
B) 7
C) 18
D) 10

10) The glycoprotein of kid blood group are ________ transporter .

A) Iron
B) Urea
C) Co2
D) Oxygen

11) The kid blood group N and C terminus are present _________.
A) Intracellular
B) Extracellular
C) N terminus extracellular and C terminus intracellular .
D) Both are extracellular

1. What is the primary cause of Hemolytic Disease of the Newborn (HDN)?

A) Maternal infection
B) Maternal Rh incompatibility
C) Premature birth
D) Genetic mutation
Answer: B) Maternal Rh incompatibility

2. Which blood type is most commonly associated with HDN?

A) O+
B) AB-
C) A+
D) Rh-
Answer: D) Rh-

3. What is the main antibody responsible for causing HDN in Rh-incompatible pregnancies?
A) IgA
 B) IgM
C) IgD
D) IgG
Answer: D) IgG

4. Which of the following is NOT a common symptom of HDN in a newborn?

A) Jaundice
B) Anemia
C) High blood pressure
D) Enlarged spleen
Answer: C) High blood pressure

5. How can HDN be prevented in Rh-negative mothers carrying an Rh-positive fetus?

A) Blood transfusion for the newborn
B) Rh immunoglobulin (RhIg) injections during pregnancy
C) Early induction of labor
D) None of the above
Answer: B) Rh immunoglobulin (RhIg) injections during pregnancy

6. What diagnostic test is commonly used to assess the severity of HDN in a newborn?
A) Magnetic resonance imaging (MRI)
B) Complete blood count (CBC)
C) Amniocentesis
D) Bilirubin level measurement
Answer: D) Bilirubin level measurement

7. In severe cases of HDN, what treatment option may be required for the newborn?
A) Antibiotics
B) Blood transfusion
C) Oxygen therapy
D) IV fluids
Answer: B) Blood transfusion

8. Which of the following is a risk factor for developing HDN?

A) Maternal smoking
B) Maternal age over 40
C) First pregnancy
D) Maternal Rh sensitization
Answer: D) Maternal Rh sensitization

9. What is the main goal of treatment for a newborn with HDN?

A) Reduce maternal blood pressure
B) Promote early weaning from breast milk
C) Manage bilirubin levels and prevent complications
 D) Provide pain relief
Answer: C) Manage bilirubin levels and prevent complications

10. Which blood component is most affected in HDN?

A) White blood cells
B) Platelets
C) Red blood cells
D) Plasma
Answer: C) Red blood cells