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Institutional Biosafety Committee (IBC) | EHS https://www.ehs.washington.edu/biological/institutional-biosafety-comm...
All work involving biohazards, including recombinant or synthetic DNA/RNA, is reviewed by the Institutional
Biosafety Committee (IBC) and EH&S. The National Institutes of Health (NIH) require us to have an IBC. The
committee approves procedures for procurement, use, storage, transportation and disposal of biohazardous
material.
IBC Policies
Viral Vectors
Viral Vectors for Gene Transfer (/biological/viral-vectors-gene-transfer) lists the most commonly used viral
vectors and options for replication competent virus (RCV) testing. Some vectors can be used at a lower
biosafety level if tested negative for RCV. Contact EH&S �rst to con�rm that RCV testing is an option for your
proposed work.
The IBC has established a working de�nition of third generation lentiviral vectors. If vectors meet the
de�nition of third generation, biocontainment may be lowered for use with oncogenic inserts. Refer to Third
Generation Lentiviral Vectors (http://www.ehs.washington.edu/system/�les/resources/third-gen-lenti.pdf) for
more information.
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Institutional Biosafety Committee (IBC) | EHS https://www.ehs.washington.edu/biological/institutional-biosafety-comm...
The IBC reviews applications for Biological Use Authorizations (BUAs) during meetings. You must submit a
complete and accurate BUA application (http://www.ehs.washington.edu/system/�les/resources/bua-
application.docx) or a Request for Change to BUA application (http://www.ehs.washington.edu/system/�les
/resources/bua-change.docx) by 5:00 p.m. four weeks prior to the meeting at which you’d like your project to
be reviewed. Clinical trial BUA applications (http://www.ehs.washington.edu/resource/clinical-trial-biological-
use-authorization-bua-application-604) may require up to six weeks for review. Refer to the BUA submission
deadlines (https://www.ehs.washington.edu/system/�les/resources/BUA-submission-dates.pdf).
The IBC will review BUA applications and clinical trial BUA applications according to a pre-determined process
(http://www.ehs.washington.edu/system/�les/resources/IBC-project-review.pdf).
Meeting Minutes
2023 IBC Meeting Minutes
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Institutional Biosafety Committee (IBC) | EHS https://www.ehs.washington.edu/biological/institutional-biosafety-comm...
Prior to 2014
More information
Trainings
CONTACT
REFERENCE FILES
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Institutional Biosafety Committee (IBC) | EHS https://www.ehs.washington.edu/biological/institutional-biosafety-comm...
367.81KB (.docx)
REFERENCE LINKS
(http://www.washington.edu/boundless/)
© 20 UW Environmental Health & Safety Department | 201 Hall Health Center, Box 354400, Seattle, WA | Tel: 206.543.7262 | Fax:
206.543.3351 | ehsdept@uw.edu (mailto:ehsdept@uw.edu)
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