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MULTIPLE CHOICE
4. Of the five epidermal cell layers, the only one that can undergo mitosis is the stratum:
a. basale.
b. lucidum.
c. corneum.
d. granulosum.
ANS: A DIF: Memorization REF: p. 183
TOP: Cell Layers
6. The hypodermis:
a. connects the dermis to underlying tissues.
b. is the layer of skin in which hair is produced.
c. connects the dermis and the epidermis.
d. is the layer of skin in which the nails are produced.
ANS: A DIF: Memorization REF: p. 188
TOP: Hypodermis
7. In what area of the body would you expect to find an especially thick stratum corneum?
a. Back of the hand
b. Thigh
c. Abdomen
d. Sole of the foot
ANS: D DIF: Synthesis REF: p. 181 TOP: Thin and Thick Skin
9. Smooth muscles that produce goose pimples when they contract are the _____ muscles.
a. papillary
b. cuticle
c. medullary
d. arrector pili
ANS: D DIF: Memorization REF: p. 187
TOP: Reticular Layer
14. Fingernail growth is the result of the mitosis of the cells in the stratum:
a. germinativum.
b. granulosum.
c. corneum.
d. lucidum.
ANS: A DIF: Memorization REF: p. 197
TOP: Nails
15. Apocrine sweat glands can be found in all of the following areas except the:
a. soles of the feet.
b. armpits.
c. areolae of the breasts.
d. pigmented skin areas around the anus.
ANS: A DIF: Application REF: p. 199 TOP: Apocrine Glands
18. Hair:
a. alternates between periods of growth and rest.
b. consists of keratinized cells.
c. is formed from cells of the germinal matrix.
d. is all of the above.
ANS: D DIF: Synthesis REF: p. 195 TOP: Hair
20. The most numerous, important, and widespread sweat glands in the body are:
a. apocrine.
b. eccrine.
c. ceruminous.
d. sebaceous.
ANS: B DIF: Memorization REF: p. 198
TOP: Sweat Glands
21. Sebum:
a. lubricates hair and skin.
b. is produced by sweat glands.
c. consists of dead cells from hair follicles.
d. is responsible for body odor.
ANS: A DIF: Synthesis REF: p. 199 TOP: Sebaceous Glands
23. The surface film found on the skin has a variety of functions, including:
a. lubrication.
b. buffering of caustic irritants.
c. antibacterial and antifungal activity.
d. all of the above.
ANS: D DIF: Application REF: p. 192 TOP: Surface Film
24. Although body temperature normally changes very little during the course of a day, it is
generally the lowest during:
a. the early morning.
b. mid-afternoon.
c. late afternoon.
d. the evening.
ANS: A DIF: Application REF: p. 193
TOP: Homeostasis of Body Temperature
25. The conversion of water from a liquid state into a gaseous state happens with which form
of body heat loss?
a. Convection
b. Evaporation
c. Radiation
d. Conduction
ANS: B DIF: Synthesis REF: pp. 193-194 TOP: Evaporation
26. Which type of body heat loss is characterized by heat transfer from the surface of one
object to the surface of another object without actual contact?
a. Convection
b. Evaporation
c. Radiation
d. Conduction
ANS: C DIF: Memorization REF: p. 194
TOP: Radiation
27. The body compensates for the increase in the core body temperature caused by exercise
by:
a. decreasing the blood flow to the skin.
b. increasing the blood flow to the core.
c. increasing the blood flow to the skin.
d. vasoconstriction of the blood vessels in the skin.
ANS: C DIF: Memorization REF: p. 193
TOP: Heat Loss
28. The same degree of environmental temperature seems hotter in humid climates than it
does in dry ones because:
a. evaporation increases in humid climates.
b. evaporation is retarded in humid climates.
c. radiation is increased in humid climates.
d. humid climates alter the temperature receptors in the hypothalamus by
mechanisms unknown.
ANS: B DIF: Application REF: p. 194 TOP: Evaporation
29. A person leaning against a cold cement block wall would lose heat by the process of:
a. convection.
b. evaporation.
c. radiation.
d. conduction.
ANS: D DIF: Synthesis REF: p. 194 TOP: Conduction
32. A major distinction between second- and third-degree burns is that third-degree burns:
a. involve injury to only the deep epidermal layers.
b. involve damage to only hair follicles.
c. involve damage to only the sweat glands.
d. are characterized by insensitivity to pain immediately after injury.
ANS: D DIF: Synthesis REF: p. 202
TOP: Estimating Body Surface Area (Mechanisms of Disease)
35. Which cells originate in the bone marrow and are important in the immune function?
a. Dendritic cells
b. Melanocytes
c. Keratinocytes
d. Fibroblasts
ANS: A DIF: Memorization REF: p. 183
TOP: Cell Types
37. Which skin layer has cells that look prickly because of the desmosomes that join the cells
together?
a. Stratum basale
b. Stratum spinosum
c. Stratum granulosum
d. Stratum corneum
ANS: B DIF: Memorization REF: p. 183
TOP: Cell Layer
38. Which skin layer contains closely packed, clear cells that contain a gel-like substance
called eleidin?
a. Stratum lucidum
b. Stratum basale
c. Stratum granulosum
d. Stratum corneum
ANS: A DIF: Memorization REF: p. 184
TOP: Cell Layers
40. Normally, which percentage of the cells in the stratum basale enter mitosis each day?
a. 20% to 25%
b. 10% to 12%
c. 18% to 20%
d. 35% to 40%
ANS: B DIF: Memorization REF: p. 184
TOP: Epidermal Growth and Repair
44. The area of the skin in an average-size adult is about _____ square feet.
a. 12
b. 18
c. 24
d. 31
ANS: B DIF: Memorization REF: p. 181
TOP: Introduction
45. The term used to describe the skin and its appendages is:
a. epidermis.
b. dermis.
c. integumentary system.
d. integument.
ANS: C DIF: Memorization REF: p. 181
TOP: Introduction
46. Which cells of the skin are filled with a tough, fibrous protein and account for most of the
epidermal cells of the skin?
a. Dermatocytes
b. Langerhans cells
c. Keratinocytes
d. Melanocytes
ANS: C DIF: Memorization REF: p. 183
TOP: Cell Types
47. Which cells of the skin act as a type of antigen-presenting cell in the skin?
a. Dermatocytes
b. Dendritic cells
c. Keratinocytes
d. Melanocytes
ANS: B DIF: Memorization REF: p. 183
TOP: Cell Types
48. The cell layers of skin from the most superficial to the deepest appear in what order?
a. Stratum corneum, lucidum, granulosum, spinosum, and basale
b. Stratum basale, spinosum, granulosum, lucidum, and corneum
c. Stratum basale, granulosum, lucidum, spinosum, and corneum
d. Stratum corneum, granulosum, lucidum, spinosum, and basale
ANS: A DIF: Application REF: pp. 183-184 TOP: Cell Layers
49. The time required for the completion of mitosis, differentiation, and the movement of new
cells from the stratum basale to the surface of the skin is about:
a. 35 hours.
b. 17 days.
c. 22 days.
d. 35 days.
ANS: D DIF: Memorization REF: p. 184
TOP: Epidermal Growth and Repair
50. To increase the efficiency of protein synthesis, cells in which epidermal layer are rich in
RNA?
a. Stratum corneum
b. Stratum lucidum
c. Stratum spinosum
d. Stratum granulosum
ANS: C DIF: Memorization REF: p. 183
TOP: Cell Layers
51. Cells in which layer are filled with a protein called eleidin?
a. Stratum corneum
b. Stratum lucidum
c. Stratum spinosum
d. Stratum granulosum
ANS: B DIF: Memorization REF: p. 184
TOP: Cell Layers
52. Cells in which layer have a high level of lysosomal enzymes in their cytoplasm?
a. Stratum corneum
b. Stratum lucidum
c. Stratum spinosum
d. Stratum granulosum
ANS: D DIF: Memorization REF: p. 184
TOP: Cell Layers
55. When the skin looks cyanotic, it is because _____ can be seen through the skin.
a. oxygen-poor blood
b. oxygen-rich blood
c. hemosiderin
d. bile pigments
ANS: A DIF: Application REF: p. 190 TOP: Other Pigments
57. What increase in body temperature can be caused by anesthetics or muscle relaxants?
a. Heat exhaustion
b. Heat stroke
c. Fever
d. Malignant hyperthermia
ANS: D DIF: Memorization REF: p. 202
TOP: Abnormal Body Temperature (Mechanisms of Disease)
59. Many liquid medicines, such as insulin, are administered using a subcutaneous injection.
Why is the subcutaneous layer an ideal site for the administration of such medication?
a. The subcutaneous layer is rich in blood supply and nerve networks.
b. The subcutaneous layer has a rich blood supply and loose spongy texture.
c. The subcutaneous layer has a rich blood supply and firm texture.
d. The subcutaneous layer has a rich supply of nerves and loose spongy texture.
ANS: B DIF: Application REF: p. 188
TOP: Subcutaneous and Intradermal Injections (Box 10-3)
61. After several hours of landscaping the yard, Jennifer experienced a body temperature of
105° F; a rapid heart rate; headache; and hot, dry skin. She was taken to a medical facility
and treated for what condition?
a. Heat exhaustion
b. Heat stroke
c. Hypothermia
d. Malignant hyperthermia
ANS: B DIF: Application REF: p. 202
TOP: Abnormal Body Temperature (Mechanisms of Disease)
62. Matt is admitted to the hospital with burns to the deep epidermal layers and injury to the
upper layers of the dermis. The physician treats Matt’s condition as a _____ burn.
a. first-degree
b. hypothermia
c. minor
d. second-degree
ANS: D DIF: Application REF: p. 203
TOP: Estimating Body Surface Area (Mechanisms of Disease)
63. The special network of nerves deep in the dermis that is capable of detecting pressure on
the skin surface is called:
a. free nerve endings.
b. Krause end bulbs.
c. tactile corpuscle.
d. somatic sensory receptors.
ANS: D DIF: Application REF: p. 186 TOP: Dermis
64. Which statement best explains the importance of the dendritic cells?
a. They contribute color to the skin and serve to decrease the amount of ultraviolet
light that can penetrate into the deeper layers of the skin.
b. They become filled with a tough, fibrous protein called keratin.
c. They find markers on bacteria and other invaders and present them to other
immune system cells for recognition and destruction.
d. They form the attachment of the hair follicle with the arrector pili muscles.
ANS: C DIF: Application REF: p. 183 TOP: Cell Types
65. How can the regeneration time required for completion of mitosis, differentiation, and
movement of new keratinocytes from the stratum basale to the surface of the epidermis be
accelerated?
a. By abrasion of the skin surface
b. By the presence of eleidin
c. By the epidermal proliferating unit
d. By the presence of dermal-epidermal junctions
ANS: C DIF: Application REF: p. 184 TOP: Cell Types
66. The fibers in which layer make it possible for skin to stretch and be elastic?
a. Connective tissue
b. Epidermal
c. Muscle
d. Reticular
ANS: D DIF: Application REF: p. 187 TOP: Reticular Layer
67. After several months of extensive weight training, Nick has noticed pinkish, depressed
furrows with jagged edges in his axillary region. These markings are a result of:
a. a decrease in dermal papillae.
b. healing due to tiny tears in the dermis.
c. malfunction of the microvilli.
d. overproduction of the arrector pili muscles.
ANS: B DIF: Application REF: p. 187 TOP: Dermal Growth and
Repair
68. If you were looking under the microscope at a slide that contains skin glands, what three
kinds of microscopic glands would be present?
a. Sebaceous, eccrine, and ceruminous glands
b. Sweat, eccrine, and ceruminous glands
c. Sweat, eccrine, and sebaceous glands
d. Sweat, sebaceous, and ceruminous glands
ANS: D DIF: Application REF: pp. 198-199 TOP: Sweat Glands
69. Yellowish discoloration of the skin and other tissues is a condition known as jaundice.
This results from the:
a. gallbladder not being able to eliminate bile from the blood efficiently.
b. liver not being able to eliminate bile from the blood efficiently.
c. liver not being able to eliminate hemoglobin from the blood efficiently.
d. red blood cells not being able to eliminate hemoglobin.
ANS: B DIF: Application REF: p. 190 TOP: Jaundice (Box 10-4)
71. The skin of an infant is more easily damaged by penetration or abrasion than that of an
adult. Which layer is probably thinner in an infant than in an adult?
a. Stratum basale
b. Stratum corneum
c. Stratum lucidum
d. Stratum spinosum
ANS: B DIF: Application REF: p. 184 TOP: Cell Layers
72. A geneticist informs parents that their newborn infant does not have the enzyme
tyrosinase. The lack of this enzyme will result in:
a. albinism.
b. malignant hyperthermia.
c. scleroderma.
d. vitiligo.
ANS: A DIF: Application REF: p. 189 TOP: Skin Color
73. Which of the following is not true about thick or thin skin?
a. Thin skin is hairless.
b. Most of the body is covered in thin skin.
c. Epidermal ridges are found in thick skin.
d. All of the above are true.
ANS: A DIF: Memorization REF: p. 181
TOP: Thin and Thick Skin
74. Which of the following is not true of dermal growth and repair?
a. Just as the epidermis, the dermis is in a constant state of regeneration.
b. In the healing of an injury, fibroblasts reproduce and begin to form new connective
tissue.
c. Surgical incisions made parallel to cleavage lines are less likely to leave a scar.
d. All of the above statements are true.
ANS: A DIF: Memorization REF: p. 184
TOP: Dermal Growth and Repair
76. The excretory function of the skin includes all of the following except:
a. influencing the fluid volume of the body.
b. playing an important excretory role for the body.
c. removing uric acid and urea from the body.
d. The excretory function includes all of the above.
ANS: B DIF: Memorization REF: p. 192
TOP: Excretion
77. Which of the following is not true of the body’s ability to regulate heat loss?
a. It is part of a negative-feedback mechanism.
b. Sweat glands increase the production of sweat.
c. The homeostatic regulation of body temperature is regulated by the thyroid gland.
d. All of the above are true.
ANS: C DIF: Memorization REF: p. 193
TOP: Homeostatic Regulation of Heat Loss
TRUE/FALSE
3. The hypodermis is a subcutaneous layer rich in adipose and loose fibrous connective
tissue.
9. A primary function of the dermal-epidermal junction is to “glue” together the dermis and
the epidermis.
11. Normally about 10% to 12% of all cells in the stratum basale enter mitosis each day.
12. Both the epidermis and the dermis continually undergo shedding and regeneration.
14. Goose pimples, elevation of the testes, and erection of the nipples result from the
contraction of muscles in the dermis.
15. The dermis contains both voluntary and involuntary muscle fibers.
16. Malignant melanoma has been steadily increasing in the United States for the past 20
years.
18. Vitiligo is an acquired condition that results in loss of pigment in certain areas of the skin.
19. An increase in the enzyme tyrosinase will lead to the destruction of pigment and result in
albinism.
20. Darkening of the skin may be caused by a decrease in the secretion of adrenocorticotropic
hormone.
21. Lanugo is the technical term used for adult body hair.
22. Terminal hair is the coarse pubic and axillary hair that develops at puberty.
24. One of the factors associated with the common type of baldness is the presence of
testosterone.
26. The gland that produces the waxy secretion in the external ear canal is a sebaceous gland.
28. Apocrine sweat glands are the most numerous and widespread sweat glands in the body.
29. There is a more than fivefold increase in the rate of sebum secretion between 10 and 19
years of age.
30. A person with a body temperature of 38 C would need to be treated for hypothermia.
31. When heat must be conserved to maintain a constant body temperature, the dermal blood
vessels increase their diameter.
32. Shivering is a good example of the body’s attempt to produce more heat.
33. A person who is shivering would normally have dilated surface blood vessels in the skin.
37. Besides changing the rates of metabolism, the primary means of controlling body
temperature is through changes in the size of blood vessels in the skin.
40. Blisters, severe pain, generalized swelling, and edema are characteristic of third-degree
burns.
41. The rule of palms and the rule of tens are two methods used in estimating the extent of
body surface area burned.
42. Third-degree burns are less severe than first-degree burns and therefore are not as painful.
43. The thickest part of the skin is slightly more than 3 cm thick.
47. Thick skin and thin skin refer to the dermis and the epidermis.
49. In thin skin, some of the strata of the skin may be absent.
52. The stratum lucidum and stratum basale are sometimes referred to as the stratum
germinativum.
53. Blisters can be the result of damage to the desmosomes in a layer of skin.
54. The average turnover time for skin cells to go from the stratum basale to the surface of the
epidermis is about 35 days.
55. Continual abrasion to the skin surface tends to lengthen the turnover time of the skin.
56. A group of active basal cells, together with its vertical column of migrating keratinocytes,
is called a dermal proliferating unit, or DPU.
57. The papillary layer of the dermis lies just below the dermal-epidermal junction.
58. The reticular layer of the dermis serves as an attachment point for both smooth and
skeletal muscles.
59. Surgical incisions that are made perpendicular to cleavage lines tend to heal with less of a
scar.
60. Light-skinned people have fewer melanocytes in their skin than do dark-skinned people.
61. The ability of melanocytes to darken the skin is dependent on the functioning of the
enzyme tyrosinase.
62. Convection is responsible for most of the heat loss of the body.
63. The protective function of the skin is limited to the protection of the underlying tissue
from abrasion and mechanical injury.
64. The shedding of epithelial elements from the skin surface is called desquamation.
65. The surface film that aids in the protective function of the skin is remarkably consistent
from one part of the skin to another.
66. Because sweat can contain ammonia, urea, and other waste products, it plays a major role
in the excretion of body wastes.
68. Because vitamin D is a compound that influences several important chemical reactions, it
can also be classified as an enzyme.
69. Radiation can account for both heat loss and heat gain.
70. Heat production occurs in two ways: metabolism of food and absorption of heat from the
environment.
71. Sweat that drips off you does very little to cool your body.
72. In a cool environment, conduction accounts for most of the heat loss of the body.
73. In using the rule of nines to determine the area of the body involved, the body is divided
into nine areas of 11% each.
75. The cells of the germinal matrix are responsible for forming hair.
76. The hair itself is composed of three layers: the shaft, the cortex, and the cuticle.
78. Apocrine and eccrine glands are the two types of sebaceous glands.
79. Eccrine glands are the more numerous of the sweat glands.
80. Although the ducts of the eccrine sweat glands come through the epidermis, the actual
secretory portion is located in the dermis.
82. Because sebaceous glands produce a substance rich in triglycerides and fatty acids, it
provides a good growth medium for fungi.
83. Malignant hyperthermia occurs as a result of exposure to certain types of anesthetic agents
or muscle relaxants.
84. The skin surface area can be as large as 20 square feet in the average adult.
85. The skin is a thin and relatively flat organ and is an example of a serous membrane.
90. Cleavage lines and Langer lines refer to the same thing.
91. Langer lines is the more correct name for stretch marks.
93. Jaundice can occur because of a very high concentration of vitamin A in the skin.
94. A high level of melanin in the skin assists in the formation of vitamin D.
95. Dendritic cells develop in the dermis of the skin but migrate to the epidermis of the skin to
function.
96. Cells in the stratum spinosum layer are rich in RNA to make protein synthesis more
efficient.
97. Keratohyalin is a protein in the stratum lucidum that will eventually be transformed into
keratin in the cells of the epidermis.
98. Cells in the stratum lucidum do not have a high metabolic rate, because they usually do
not have a nucleus.
99. High levels of lysosomal enzymes are found in the cells of the stratum granulosum layer.
100. One end of the arrector pili muscle is attached to a hair follicle.
101. A scar is a dense mass of keratinocytes that forms when a wound to the skin heals.
102. People who have mostly pheomelanin in their skin tend to have darker skin than people
who have mostly eumelanin.
103. Melanosomes help prevent DNA mutations when the cell is exposed to ultraviolet
radiation.
104. You turn red when you blush, because the color of blood is red.
105. The presence of hemosiderin and bile pigments in the skin can cause the skin to appear
cyanotic.
106. Both the root and the lunula of the nail are covered by the cuticle and therefore cannot be
seen externally.
ANS: F DIF: Memorization REF: p. 197
TOP: Nails
107. If a person were in a totally bacteria-free environment, any sweat produced would have no
odor.
108. Chemicals that cause the body to develop a fever are called pyrogens.
109. Fever is always detrimental to the body, so the body temperature should be reduced to
normal as soon as possible.
110. Malignant hyperthermia, heat exhaustion, and heat stroke are increasingly dangerous
consequences of exposure to high environmental temperatures.
116. The stratum granulosum is sometimes called the barrier layer of the skin.
ANS: F DIF: Memorization REF: p. 184
TOP: Cell Layers
117. In order for proper growth and repair of the skin to occur, both insulin-like growth factor
and vitamin D must be present in the correct amounts.
118. The main function of the dermoepidermal junction is to act as a barrier to harmful
chemicals and bacteria.
119. Hair follicles and skin glands, made up of epithelial tissue, extend from the epidermis into
the reticular layer.
120. In the healing of a wound, fibroblasts in the dermis quickly reproduce and begin forming a
dense mass of new connective tissue fibers.
121. The death of melanocytes in the hair follicle of older people causes the hair to turn gray.
122. Permanent tattoos are made by injecting pigments into the epidermis of the skin, and
because of the regeneration of the epidermis, they become less distinct with age.
123. The germinal matrix is a small mound of dermis that supplies blood to the hair follicle.
124. The hair follicle serves as a primary location of adult stem cells for skin cells like
melanocytes.
125. Toenails and fingernails grow at the rate of about 0.5 mm a week, but they grow faster in
the winter than they do in the summer.
ANS: F DIF: Memorization REF: p. 197
TOP: Nails
MATCHING
OTHER
1. Name and describe what occurs in the cells in each of the layers of the epidermis.
ANS:
Answers will vary.
ANS:
Answers will vary.
3. Name and describe the pigments in the skin. Which pigment is more protective against
ultraviolet radiation?
ANS:
Answers will vary.
ANS:
Answers will vary.
DIF: Synthesis REF: p. 202
TOP: Estimating Body Surface Area (Mechanisms of Disease)
5. Explain the role of the blood vessels in the skin in the homeostatic regulation of heat loss
in the body.
ANS:
Answers will vary.
6. Name and explain the methods of heat loss discussed in this chapter.
ANS:
Answers will vary.
7. Explain the protection function of the skin, and include the role of the surface film.
ANS:
Answers will vary.
8. Describe the formation of hair, and describe the parts of a hair follicle.
ANS:
Answers will vary.
9. Describe the structure of fingernails, and describe how they grow and their rate of growth.
ANS:
Answers will vary.
10. Name the two types of sweat glands. Explain the difference in their location in the body
and the substance they produce.
ANS:
Answers will vary.
11. Where are the sebaceous glands located? What do they produce, and what are the
properties or functions of the secretion?
ANS:
Answers will vary.
DIF: Application REF: p. 199 TOP: Sebaceous Glands
12. Explain the two ways in which body surface area can be estimated.
ANS:
Answers will vary.
ESSAY
1. The process of digesting food requires work from the body. Why would you expect the
body temperature to rise slightly after eating a big meal?
ANS:
Answers will vary.
2. In hospitals, frequently a sensor is put over one fingernail to determine whether the
patient’s blood is properly oxygenated. Explain why this evaluation is possible.
ANS:
Answers will vary.