Monograph

pubs.acs.org/doi/book/10.1021/acsreagents

Sodium Tartrate Dihydrate

(2,3-Dihydroxybutanedioic Acid, Disodium Salt, Dihydrate)
Part 4, Monographs for Reagent Chemicals: General Descriptions, Specifications, and Tests
eISBN: 9780841230460
Tom Tyner Chair, ACS Committee on Analytical Reagents
James Francis Secretary, ACS Committee on Analytical Reagents

ABSTRACT
This monograph for Sodium Tartrate Dihydrate provides, in addition to common physical constants, a general
description including typical appearance, applications, change in state (approximate), and aqueous solubility. The
monograph also details the following specifications and corresponding tests for verifying that a substance meets ACS
Reagent Grade specifications including: Assay, Loss on Drying, pH of a 5% Solution at 25.0 °C, Insoluble Matter,
Chloride, Phosphate, Sulfate, Ammonium, Calcium, Heavy Metals, and Iron.

(CHOHCOONa)2 • 2H2O Formula Wt 230.08 CAS No. 6106-24-7

Suitable for standardization of Karl Fischer reagent as used for the determination of trace amounts of water (less than 1%).

GENERAL DESCRIPTION
Typical appearance . . . . . . . . . . . . . . . . . . . white solid
Applications . . . . . . . . . . . . . . . . . . . . . . . . standardizing Karl Fischer reagent
Change in state (approximate) . . . . . . . . . . . . dehydrates at 120 °C
Aqueous solubility . . . . . . . . . . . . . . . . . . . . 69 g in 100 mL at 43 °C

SPECIFICATIONS
Assay . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99.0–101.0% Na2C4H4O6 · 2H2O
Loss on drying . . . . . . . . . . . . . . . . . . . . . . 15.61–15.71%
pH of a 5% solution at 25.0 °C . . . . . . . . . . . . 7.0–9.0
Maximum Allowable
Insoluble matter . . . . . . . . . . . . . . . . . . . . . 0.005%
Chloride (Cl) . . . . . . . . . . . . . . . . . . . . . . . 5 ppm

DOI:10.1021/acsreagents.4372
© 2017 American Chemical Society A ACS Reagent Chemicals, Part 4
ACS Reagent Chemicals Monograph

pubs.acs.org/doi/book/10.1021/acsreagents

Phosphate (PO4) . . . . . . . . . . . . . . . . . . . . . 5 ppm

Sulfate (SO4) . . . . . . . . . . . . . . . . . . . . . . . 0.005%
Ammonium (NH4) . . . . . . . . . . . . . . . . . . . . 0.003%
Calcium (Ca) . . . . . . . . . . . . . . . . . . . . . . . 0.01%
Heavy metals (as Pb) . . . . . . . . . . . . . . . . . . 5 ppm
Iron (Fe) . . . . . . . . . . . . . . . . . . . . . . . . . . 0.001%

TESTS
Assay
(Total alkalinity by nonaqueous titration). Weigh accurately about 0.45 g, and dissolve in 100 mL of glacial acetic acid.
Titrate with 0.1 N perchloric acid in glacial acetic acid volumetric solution to a green end point using crystal violet indicator
solution. One milliliter of 0.1 N perchloric acid corresponds to 0.01151 g of Na2C4H4O6 · 2H2O.

Loss on Drying
Weigh accurately 3.0 g into a preconditioned, low-form weighing bottle, and dry at 150 °C to constant weight (minimum 4
h).

pH of a 5% Solution at 25.0 °C
[Part 2: Direct Electrometric Methods; pH Potentiometry; pH Range; Procedure for pH of a 5% Solution at 25.0 °C].

Insoluble Matter
[Part 2: Gravimetric Methods; Insoluble Matter]. Use 20 g dissolved in 200 mL of water.

Chloride
[Part 2: Colorimetry and Turbidimetry; Chloride]. Use 2.0 g.

Phosphate
[Part 2: Colorimetry and Turbidimetry; Phosphate; Procedure for Phosphate, Method 1 (Direct Molybdenum Blue)]. Ignite
4.0 g in a platinum dish. Dissolve the residue in 5 mL of water, add 5 mL of nitric acid, and evaporate to dryness. Dissolve
the residue in 25 mL of approximately 0.5 N sulfuric acid, and continue as described.

Sulfate
Drive off any moisture on a hot plate, and then carefully ignite 1.0 g in an electric muffle furnace until it is nearly free of
carbon. Boil the residue with 10 mL of water and 0.5 mL of 30% hydrogen peroxide for 5 min. Add 5 mg of sodium carbonate
and 1 mL of hydrochloric acid, and evaporate on a hot plate (~100 °C) to dryness. Dissolve the residue in 4 mL of hot water
to which has been added 1 mL of dilute hydrochloric acid (1:19), filter through a small filter, wash with two 2 mL portions of
water, and dilute the filtrate to 10 mL. Add 1 mL of 12% barium chloride reagent solution, and mix well. Any turbidity
produced should not be greater than that in a standard prepared as described and to which the 12% barium chloride reagent

DOI:10.1021/acsreagents.4372
© 2017 American Chemical Society B ACS Reagent Chemicals, Part 4
ACS Reagent Chemicals Monograph

pubs.acs.org/doi/book/10.1021/acsreagents

solution is added at the same time it is added to the sample solution. To 10 mL of water, add 5 mg of sodium carbonate, 1
mL of hydrochloric acid, 0.5 mL of 30% hydrogen peroxide, and 0.05 mg of sulfate ion (SO4), and evaporate on a hot plate
(~100 °C) to dryness. Dissolve the residue in 9 mL of water, and add 1 mL of dilute hydrochloric acid (1:19). If necessary,
adjust with water to the same volume as the sample solution, add 1 mL of 12% barium chloride reagent solution, and mix
well.

Ammonium
Dissolve 1.0 g in 60 mL of water. To 20 mL, add 1 mL of 10% sodium hydroxide reagent solution, dilute with water to 50 mL,
and add 2 mL of Nessler reagent. Any color should not exceed that produced by 0.01 mg of ammonium ion (NH4) in an equal
volume of solution containing the quantities of reagents used in the test.

Calcium
(By flame AAS, [Part 2: Trace and Ultratrace Elemental Analysis; Atomic Absorption Spectroscopy; Analysis; Procedure for
Flame AAS]).

For the Determination of Calcium

S a m p l e S t o c k S o l u t i o n . Dissolve 10.0 g of sample with water in a 100 mL volumetric flask, add 5 mL of hydrochloric
acid, and dilute to the mark with water (1 mL = 0.1 g).

For the Determination of Calcium

Element Wavelength (nm) Sample Wt (g) Standard Added Flame Type* Background
(mg) Correction
Ca 422.7 0.50 0.05; 0.10 N/A No
*N/A is nitrous oxide/acetylene.

Heavy Metals
[Part 2: Colorimetry and Turbidimetry; Heavy Metals (as Lead); Procedure for Heavy Metals, Method 1]. Dissolve 6.0 g in
about 20 mL of water, and dilute with water to 30 mL. Use 25 mL to prepare the sample solution, and use the remaining 5.0
mL to prepare the control solution.

Iron
[Part 2: Colorimetry and Turbidimetry; Iron; Procedure for Iron, Method 1 (Ammonium Thiocyanate)]. Use 1.0 g.

DOI:10.1021/acsreagents.4372
© 2017 American Chemical Society C ACS Reagent Chemicals, Part 4