DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT NURSING RESPONSIBILITIES

CONTRAINDICATION

GENERIC: INDICATIONs: CNS: BEFORE:

SETRALINE Inhibits neuronal uptake of Major depressive disorder. Neuroleptic malignant Dx:
serotonin in the CNS, thus Panic disorder. Obsessive- syndrome, suicidal thoughts,
BRAND: a. Monitor older adults for
potentiating the activity of compulsive disorder (OCD). dizziness, drowsiness, insomnia,
fluid and sodium
ZOLOFT serotonin. Has little effect on Post-traumatic stress disorder anxiety
imbalances.
norepinephrine or dopamine. (PTSD). Social anxiety disorder
CLASS: EENT:
(SOCIAL PHOBIA). b. Assess for history of
(Discuss mechanism of action
Premenstrual dysphoric Pharyngitis, rhinitis, tinnitus, seizure disorders.
as to how it can resolve
disorder(PMDD) visual abnormalities
identified condition, signs and c. Check for allergies.
THERAPEUTIC
symptoms, or nursing CV:
ANTIDEPRESSANTS conditions) d. Assess baseline mental
CONTRAINDICATION: Chest pain, palpitations status

Hypersensitivity; concurrent GI: Tx:

PHARMACOLOGIC: use of MAO-like drugs
(linezolid or methylene blue); Diarrhea, dry mouth, a. Supervise patients at
SELECTIVE SEROTONIN SOURCE: CON Book or nausea risk for suicide closely
concurrent use of pimozide;
Drughand book (Follow APA during initial therapy.
REUPTAKE INHIBITORS oral concentrate contains
Formatting) GU:
alcohol; avoid patients with b. Perform a thorough
physical assessment to
 (SSRIS) known intolerance. Sexual dysfunction,
menstrual disorder.
DERM:
DOSAGE: DRUG TO DRUG INTERACTION:
Sweating, hot flushes, rash
50 mg. __________________
ENDO:
Diabetes
ROUTE: DRUG TO FOOD INTERACTION:
MS:
ORAL _________________
Back pain, myalgia
NEURO:
Tremor, hypertonia
MISC:
EDx:
Serotonin syndrome, fever
and thirst.
(Highlight or emphasize
adverse effects manifested by
the patient by underlining the
sign and symptoms)
establish baseline data
before drug therapy
begins, to determine
the effectiveness of
therapy, and to
evaluate for the
occurrence of any
adverse effects
associated with drug
therapy.
c. Restrict amount of
drug available to
patient.
d. Periodically assess
dose.
a. Instruct pt. to take
sertraline as directed
b. Caution pt. that
drowsiness or dizziness
may occur.
c. Educate client on drug
therapy to promote
 compliance.
d. Insure the patient takes
the medication as
prescribed.

DURING:

Dx:

a. Asses mental status for

worsening of
depression, suicidal
ideation, anxiety, social
functioning, and/or
panic
attack(especially
during initiation of
therapy and when
dosage is changed
b. Monitor mood
changes.
c. Monitor for adverse
effects (e.g. sedation,
dizziness, respiratory
dysfunctions, GU
 problems, etc).
d. Check for drug or
herbal interactions

Tx:

a. Limit drug access if

patient is suicidal to
decrease the risk of
overdose to cause
harm.
b. Administer a major
portion of dose at
bedtime as ordered if
drowsiness and
anticholinergic effect
are severe to decrease
the risk of patient injury.
c. Establish suicide
precautions for
severely depressed
patients to decrease
the risk of overdose to
cause harm.
d. Assist pt. in taking the
 medication.

EDx:

a. Instruct pt. SO to report

diarrhea, nausea,
dyspepsia, insomnia,
drowsiness, dizziness, or
persistent headache to
physician.
b. Report diarrhea,
nausea, dyspepsia,
insomnia, drowsiness,
dizziness, or persistent
headache to
physician.
c. Inform of drugs and
herbs that can interact
d. Instruct patient to
verbalize feelings and
concerns.

AFTER:

Dx:

a. Assess
 knowledge/teach
patient appropriate
use ,interventions to
reduce side effects,
and adverse symptoms
to report
b. Monitor for
effectiveness as
exhibited by a
decrease in symptoms
c. Monitor for side effects.
d. Assess for serotonin
syndrome

Tx:

a. Remember that a lot of

these drugs can cause
dizziness in the first few
weeks of taking so take
safety precautions.
b. Provide safety
measures (e.g.
adequate lighting,
raised side rails, etc.) to
 prevent injuries.
c. Provide comfort
measures (e.g. voiding
before dosing, taking
food with drug, etc.) to
help patient tolerate
drug effects.
d. Administer drug once a
day in the evening to
achieve optimal
therapeutic effects.

EDx:

a. Monitor patient
compliance to drug
therapy.
b. Monitor patient for 2-4
weeks to ascertain
onset of full
therapeutic effect.
c. Advise pt. to avoid
alcohol intake.
d. Instruct patient to
verbalize feelings and
 concerns.

categorize your NURSING RESPONSIBILITIES as to Before, During and After giving the medication and each has Dx, Tx and EDx.