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  • LYMPHOID AND MONOCYTIC SERIES Demonstration Slide

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    This document describes the cells of the lymphoid and monocytic series. It outlines the key characteristics of lymphoblasts, lymphocytes, reactive/variant lymphocytes, plasma cells, and monocytes. Lymphoblasts are large round cells with nucleoli-filled nuclei and scanty cytoplasm. Lymphocytes are small round cells with no nucleoli and slightly basophilic cytoplasm. Reactive lymphocytes are large cells with irregular nuclei and abundant blue cytoplasm. Plasma cells have eccentrically located round nuclei, basophilic cytoplasm with perinuclear halos, and cytoplasmic globules. Monocytes are large round cells with irregular nuclei, grayish-blue cytoplasm containing fine red granules.

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    This document describes the cells of the lymphoid and monocytic series. It outlines the key characteristics of lymphoblasts, lymphocytes, reactive/variant lymphocytes, plasma cells, and monocytes. Lymphoblasts are large round cells with nucleoli-filled nuclei and scanty cytoplasm. Lymphocytes are small round cells with no nucleoli and slightly basophilic cytoplasm. Reactive lymphocytes are large cells with irregular nuclei and abundant blue cytoplasm. Plasma cells have eccentrically located round nuclei, basophilic cytoplasm with perinuclear halos, and cytoplasmic globules. Monocytes are large round cells with irregular nuclei, grayish-blue cytoplasm containing fine red granules.

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    12 views4 pages

    LYMPHOID AND MONOCYTIC SERIES Demonstration Slide

    Uploaded by

    itsawesomegailmacapaz
    This document describes the cells of the lymphoid and monocytic series. It outlines the key characteristics of lymphoblasts, lymphocytes, reactive/variant lymphocytes, plasma cells, and monocytes. Lymphoblasts are large round cells with nucleoli-filled nuclei and scanty cytoplasm. Lymphocytes are small round cells with no nucleoli and slightly basophilic cytoplasm. Reactive lymphocytes are large cells with irregular nuclei and abundant blue cytoplasm. Plasma cells have eccentrically located round nuclei, basophilic cytoplasm with perinuclear halos, and cytoplasmic globules. Monocytes are large round cells with irregular nuclei, grayish-blue cytoplasm containing fine red granules.

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    of 4

    LYMPHOID AND MONOCYTIC SERIES LYMPHOBLAST (2)

    (DEMONSTRATION SLIDES)

    LYMPHOID SERIES

    Lymphoblast

     A large, round cell with round nucleus


    filled with nucleoli

     Cytoplasm is basophilic and scanty


    (sparse) or to some extent very scanty

    LYMPHOBLAST (1)
    LYMPHOCYTE REACTIVE/VARIANT LYMPHOCYTE

     A small, round cell with round nucleus  A large cell with round sometimes
    without nucleoli irregular-shaped (monocytoid or many
     Cytoplasm is scanty to moderate in shape) nucleus with or without
    amount and is slightly basophilic (color nucleoli
    is described to have robin’s egg blue  Cytoplasm is abundant and royal-blue
    appearance) in color
     The most mature cell in the lymphoid  Other shapes can be amoeboid
    or lymphocytic series (cytoplasm of the cell scalloping the
     Participates in humoral immunity surrounding RBC’s)
     Size of the cell vary responsible for its  Otherwise known as atypical
    variations lymphocyte or virocyte (a cell reactive
     Small lymphocyte (commonly to provoking viral infection)
    encountered in blood smear), medium
    lymphocyte and large lymphocyte
     In examinations, lymphocyte alone is a
    correct answer
    REACTIVE/VARIANT LYMPHOCYTE PLASMA CELL
     A large cell with round nucleus that is
    eccentrically located
     Cytoplasm is abundant and is
    basophilic with characteristic area of
    hof or perinuclear halo (an unstained
    portion extending from the nucleus)
     Cytoplasm is also filled with globules
    (hole-like structures) named as russell
    bodies (accumulated
    immunoglobulins)
     Also otherwise known as PLASMACYTE
     A large lymphocyte
     Main function is antibody production
     The specific lymphocyte lineage is B-
    lymphocyte
     When seen only in the bone marrow,
    the condition associated is multiple
    myeloma
     When seen in the blood smear, the
    condition associated is plasma cell
    leukemia
    MONOCYTIC SERIES MONOCYTE (2)
    MONOCYTE
     A large, round cell with monocytoid
    (irregular or many shape) nucleus
     Nucleus morphology may vary from
    round, semi-round to horse-shoe
    shaped and brain-like convoluted
    shaped
     Cytoplasm is abundant and is grayish-
    blue in color filled with fine red
    granules (ground-glass appearance –
    turbid looking)
     Cytoplasm usually contain vacuoles
    (remnants of phagocytosis)
     Also otherwise known as
    MONONUCLEAR PHAGOCYTE
    (mononuclear because it only has one
    nucleus not segmented)
     The tissue equivalent of this cell is
    MACROPHAGE
     The largest white blood cell in the
    circulation
    MONOCYTE (1)

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