DRUG STUDY
NAME Deluvio, Donne Louis Raphael D
SECTION BSN 2B
Name of Drug Mechanism of Action
Generic Name Bisacodyl is a stimulant
Bisacodyl laxative that stimulates the
smooth muscle of the
Brand Name intestines, causing normal
Dulcolax peristalsis and increasing
water in the intestines,
Drug Class resulting in a bowel
Laxative movement. Bisacodyl
stimulates adenylate
Route of Administration cyclase, increasing cyclic
Oral: tablet AMP, leading to active
Rectal: suppositories transport of chloride and
bicarbonate out of cells.
Dosage Sodium ions, potassium
The usual oral dose for ions, and water passively
adults is 5-15 mg taken leave the cell; while sodium
once daily before bedtime and chloride ions are
or as directed by a unable to be reabsorbed.
healthcare provider. The
dosage for suppositories Onset: For oral
may vary. administration, the onset
of action is generally within
6 to 12 hours.
Suppositories may have a
quicker onset, usually
within 15 to 60 minutes.
Peak Action: The peak
action time can vary, but
COURSE
PRESENTED TO Mr. Ronald Jayson E. Torres, RN
Indication
Bisacodyl is primarily used
for the short-term
treatment of constipation
and to prepare the bowel
for certain medical
procedures or surgeries. It
is a stimulant laxative that
works by increasing
intestinal motility and
promoting bowel
movements.
Indications:
1.Constipation: Provides
relief by stimulating bowel
movements, making it
easier to pass stool.
2.Bowel Preparation: Used
before certain medical
procedures or surgeries to
clear the bowel.
Considerations:
1.Short-term Use: Typically
recommended for short
durations to avoid
dependence.
2.Precautions in Specific
Pharmacology
Contraindication
1.Dehydration: Bisacodyl
can exacerbate dehydration
due to its laxative effect.
Caution is advised,
especially in individuals
prone to dehydration or
with fluid imbalance.
2.Gastrointestinal
Disorders: Individuals with
inflammatory bowel
diseases (such as Crohn’s
disease or ulcerative colitis)
or severe abdominal pain
should use bisacodyl
cautiously, as it may
worsen these conditions.
3.Elderly Population: The
elderly may be more
sensitive to the effects of
bisacodyl, and caution is
recommended to prevent
excessive fluid loss and
electrolyte imbalance.
4.Pregnancy and
Breastfeeding: Limited data
are available on bisacodyl
use during pregnancy or
breastfeeding. Healthcare
Side Effects
1.Abdominal Discomfort:
Cramps or discomfort in
the abdominal region.
2.Diarrhea: Excessive bowel
movements leading to
loose stools.
3.Nausea: Feeling of
sickness or queasiness.
4.Dehydration: Especially if
not enough fluids are
consumed.
5.Electrolyte Imbalance:
Prolonged use may lead to
imbalances in electrolytes
like potassium.
6.Rectal Irritation: When
used as a suppository, it
may cause irritation in the
rectal area.
7.Dizziness: Some
individuals may experience
dizziness.
8.Weakness or Fatigue:
Especially if dehydration or
electrolyte imbalances
occur.
CONCEPT Gastro Intestine
SUBMITTED ON October 26, 2023
Adverse Effects
Gastrointestinal System:
1.Abdominal Cramps:
Common discomfort in the
abdominal region.
2.Diarrhea: Excessive bowel
movements leading to
loose stools.
3.Rectal Irritation: When
bisacodyl is used as a
suppository.
Fluid and Electrolyte
Balance:
4. Dehydration: Especially if
not enough fluids are
consumed.
5. Electrolyte Imbalance:
Prolonged use may lead to
imbalances, particularly
potassium.
General Systemic Effects:
6. Weakness or Fatigue:
Especially if dehydration or
electrolyte imbalances
occur.
Nursing Responsibilities
1. Assessment:
•Obtain a thorough medical
history, including gastrointestinal
issues, allergies, and medications.
•Assess the patient’s bowel habits,
including frequency and
consistency.
•Evaluate fluid and electrolyte
balance, especially in elderly
patients.
2. Diagnosis:
•Diagnose potential nursing
diagnoses, such as “Risk for Fluid
Volume Deficit” related to
diarrhea.
3. Planning:
•Collaborate with the healthcare
team to establish realistic goals,
like maintaining bowel regularity
without complications.
•Develop an individualized care
plan based on the patient’s needs
and preferences.
4. Intervention:
1
 DRUG STUDY GENERIC NAME Bisacodyl
Name of Drug Mechanism of Action
for oral administration, it is
often within 6 to 12 hours.
Duration: The duration of
action can range from 6 to
24 hours, depending on the
individual’s response and
the specific formulation
used.
Pharmacokinetics (ADME)
Absorption: Bisacodyl is
absorbed in the small
intestine after oral
administration and can also
be absorbed through the
rectal mucosa when
administered as a
suppository.
Distribution: Once
absorbed, bisacodyl is
distributed throughout the
body via the bloodstream.
Metabolism: Bisacodyl
undergoes minimal
metabolism in the liver. The
majority of the drug
remains in its active form.
Excretion: The drug and its
metabolites are primarily
excreted in the feces, with
only a small portion
eliminated in the urine.
Reference:
https://go.drugbank.com/drugs
/DB09020?ssp=1&setlang=en-
PH&safesearch=moderate
NAME Torres, Ronald Jayson E.
Indication
Populations: Caution in
pregnant or breastfeeding
women; consult a
healthcare professional for
guidance.
Not Recommended For:
1.Chronic Constipation:
Bisacodyl is generally not
recommended for long-
term use to manage
chronic constipation.
COURSE
BRAND NAME Dulcolax
Contraindication
providers may weigh the
potential benefits against
potential risks and opt for
alternative options.
Drug Interactions:
1.Diuretics: Concurrent use
of bisacodyl with diuretics
may increase the risk of
electrolyte imbalance.
2.Antacids or Milk: These
may interfere with the
enteric coating of some
bisacodyl formulations,
potentially affecting its
release and effectiveness.
3.Other Laxatives:
Concurrent use of multiple
laxatives can lead to
excessive bowel
stimulation, dehydration,
and electrolyte imbalance.
Pharmacology
DRUG CLASS Laxative
Side Effects Adverse Effects Nursing Responsibilities
7. Dizziness: Some •Administer bisacodyl as
individuals may experience prescribed, considering the route
dizziness. (oral or suppository).
•Encourage adequate fluid intake
to prevent dehydration.
•Monitor bowel movements and
assess stool consistency.
•Educate the patient on the
importance of maintaining a
balanced diet and fluid intake.
5. Evaluation:
•Assess the effectiveness of
bisacodyl in relieving constipation.
•Monitor for side effects and
adverse reactions.
•Evaluate the patient’s
understanding of medication
administration and potential
complications.
Assessment Findings to Watch
Out For:
•Abdominal pain or cramps, which
may indicate intolerance to the
medication.
•Signs of dehydration, such as
increased thirst, dark urine, or dry
mucous membranes.
•Electrolyte imbalances,
presenting as weakness, fatigue, or
irregular heartbeats.
•Changes in bowel habits that
persist or worsen.
CONCEPT Reproductive System 2
 DRUG STUDY GENERIC NAME Bisacodyl BRAND NAME Dulcolax DRUG CLASS Laxative

Name of Drug Mechanism of Action Indication Contraindication Side Effects Adverse Effects Nursing Responsibilities

NAME Torres, Ronald Jayson E. COURSE Pharmacology CONCEPT Reproductive System 3