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Digital Magazine: Physical Activity and Sports
How to cite:López-Mejía, VA; Christmas Eve-Serna, R.; Hernández-Alvarado, MF; Méndez-Ávila, JC; Morales-Hernández, AG 2023. Isometric exercises as a
therapeutic measure to control high blood pressure in adults. Literature review. Digital Magazine: Physical Activity and Sports. 9(1):e2209. http://doi. org/
10.31910/rdafd.v9.n1.2023.2209
Open access article published by Digital Magazine: Physical Activity and Sports, under a Creative Commons CC BY-NC 4.0 license
Official publication of the University of Applied and Environmental Sciences UDCA, High Quality Accredited Higher Education Institution by the Ministry of
National Education.
SUMMARY
existing treatments for high blood pressure, due to
its short duration and easy application.
Introduction:The implementation of isometric
exercises, as a therapeutic measure in patients with Keywords:Hypertension; Isometric training;
high blood pressure, can help maintain or reduce Blood pressure; Circulatory system; Healthy life
blood pressure, therefore, it is important to style.
evaluate the response to treatment and prevent the
progression of the hypertensive state.General ABSTRACT
objective:Analyze the application of protocols
isometric exercises in patients with hypertensionIntroduction:The implementation of isometric
arterial, to reduce its prevalence in the population exercises as a therapeutic measure in patients with
adult.Materials and methods:search was carried out arterial hypertension can help keep or reduce blood
on the effects of isometric pressure training. Therefore, it is important to evaluate the
adult patients with arterial hypertension, in response to treatment and prevent the advancement
the databases: PubMed, Cochrane Library, SciELO of the hypertensive state.Objective:To analyze the
and Medline, between 2015 and 2021.Results application of isometric exercise protocols in patients
and discussion:Isometric training programs, with arterial hypertension to reduce its prevalence in
such as isometric squat and isometric grip, the adult population.Materials and methods:
periodized between 4, 8 and 12 weeks, show Research was carried out on the effects of isometric
significant reduction in blood pressure (BP), in 4-5 training in adult patients with arterial hypertension in
mmHg, 4-7 mmHg and 8-9 mmHg, in population the databases: PubMed, Cochrane Library, SciELO
adult.Conclusion:From the different and Medline, between the years (2015 - 2021). reviews,
isometric exercises are considered Results and discussion:Isometric training programs
as a safe therapeutic tool, under a good dosage such as isometric squat and isometric grip periodized
and a great complement to between 4, 8 and 12 weeks show significant reduction
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López-Mejía, VA; Christmas Eve-Serna, R.; Hernández-Alvarado, MF; Méndez-Ávila,
JC; Morales-Hernández, AG: management of high blood pressure
in blood pressure (BP) in 4-5 mmHg, 4-7 mmHg and mmHg or Diastolic Blood Pressure - DBP ≥ 90-99
8-9 mmHg in adult population.Conclusion:Based on mmHg (Williamset al.2019).
the different reviews, isometric exercises are
considered a safe therapeutic tool under good dosage In the 2017 guideline, from the American Heart
and a great complement to existing treatments for Association and the American College of Cardiology,
arterial hypertension due to their short duration and AHA/ACC, it is proposed to reduce the cut-off point
easy application. for the diagnosis of HTN to >130/80mmHg, as well
as to initiate pharmacological treatment in patients
Keywords:Hypertension; Isometric training Blood in stage 1 (130-140/80-90 mmHg) and at high risk
pressure; Circulatory system; Healthy Lifestyle. (Wheltonet al.2018). On the other hand, the
European Society of Cardiology and the European
INTRODUCTION Society of Hypertension, ESC/ESH point out that, in
patients with borderline or high blood pressure
Data provided by the World Health Organization, (130-139/80-89 mmHg), lifestyle modifications
WHO (2021) estimate that, in the world, there are should be indicated, diet and exercise. At the same
1,280 million adults between 30 and 79 years of time, it is highlighted that physical exercise has
age, with High Blood Pressure-HTN and that, the been considered one of the crucial elements in
majority of them (about two-thirds), live in low- controlling BP levels, and it has also been shown
and middle-income countries. According to that aerobic resistance training, dynamic resistance
estimates, 46% of hypertensive adults are and isometric exercise reduce BP. /DBP at rest,
unaware that they have this condition. 2.5-3.5, 2.8-3.2, 6.2-10.9 mmHg, respectively
Hypertension is diagnosed and treated in less (Williamset al.2019).
than half of the adults who have it; only 42%. Only
one in five hypertensive adults (21%) is controlled. Thus, currently, the diagnosis and treatment
guidelines for HBP indicate that a reduction of 5 -
In Mexico, in adults over 19 years of age, about 10 mmHg in SBP is associated with significant
25.5 million people are carriers of HTN; Of these, reductions in serious cardiovascular
40% ignore it. Of the 60% who know, only half complications (20%), mortality from all causes
take medication and of this half, their control ( 10-15%), stroke (35%), coronary complications
figures are <140/90 mmHg. Different surveys (20%) and heart failure (40%) (Williamset al.2019).
carried out in Mexico, between 1993 and 2012,
report a prevalence of around 30%. Although a Muscular system.Muscles are translating
study based on the results of the National Health elements that convert chemical energy into
and Nutrition Survey reports a prevalence of useful electrical, thermal or mechanical energy.
arterial hypertension of 25.5%, in adults aged 20 Muscles have different shapes and sizes and
years and older (Campos-Nonatoet al.2018). differ in the forces they can exert and the
speed of their action (Córdova Martínez, 2013).
Blood Pressure-BP is the resistance force The basic physiological property of muscle
exerted by the walls of blood vessels on blood tissue is contractility, responsible for the
flow (Grossman & Porth, 2014) and a persistent functions of movement, pressure and force, as
increase in it is known as HBP, considered by well as the properties of excitability, due to the
the WHO, as the number one risk factor, presence of special neuromuscular structures
worldwide, associated with the appearance of in the membrane of the muscle cell, the motor
serious disorders that significantly increase the plate. Extensibility and elasticity depend on the
risk of connective component that protects and covers
suffer from heart disease, encephalopathy, nephropathy, contractile structures and, on the other hand,
among other diseases and even reaching the They provide elastic and mechanical properties to the
death. Álvarez-Aguilar (2015) described that tissue (Córdova Martínez, 2013).
lack of treatment can shorten people's lives by
up to 5 years. High blood pressure is defined as
a Systolic Blood Pressure - SBP ≥ 140-159.
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Rev. Digital Act. Phys. Sport 9(1):e2209. July-December, 2023
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López-Mejía, VA; Christmas Eve-Serna, R.; Hernández-Alvarado, MF; Méndez-Ávila,
JC; Morales-Hernández, AG: management of high blood pressure
#
Frequency/
Author Intervention Muscles I repeated Intensity Population Age Variables
Duration
tions
Frequency
Training Cardiac
resistance Leg 3 x week Men Cardiac output
(Wileset 4x2
isometric (Quadriceps, for 4 NR n=28 (30 +- 7 Endurance
to the.2017) min
Squats buttocks) weeks years) Total Peripheral
against the wall Volume
Systolic
Hand/Forearm Blood pressure
Training or (Muscles 5 - 30% Men Systolic
(Carlson 3 x week
resistance intrinsic of 4x2 contraction /Women Blood pressure
et al. for 8 n=40
isometric hand – flexors min volunteer (36 - 65 Diastolic
2016) weeks
(handle) and extenders maximum years) Blood pressure
forearm) Half
Leg Aerobics
(Quadriceps, 60%
Exercises
hamstrings, 30 min consumption
aerobics
buttocks, Maximum of
Men Carotid
gastrocnemius) oxygen
(Ashet al. NR/8 /Women Femoral
Hand/Forearm n=27
2017) weeks (18 - 55 Blood pressure
or (Muscles IHG 30%
exercises years) (MAP)
intrinsic of 4x2 contraction
handle
hand – flexors min maximum
isometric
and extenders volunteer
forearm)
Training Hand/Forearm
grip or (Muscles 2x2
5 x week
isometric intrinsic of min
for 12
Training hand – flexors by
weeks Men
(Pagonas drill and extenders arm 30%
/Women Blood pressure
et al. grip forearm) contraction n=75
(40 - 75 (MAP)
2017) Leg maximum
years)
(Quadriceps,
Training 3-5 times x
hamstrings, 30 min
aerobic week
buttocks,
gastrocnemius)
Training Men Blood pressure
Leg
(Wileset Isometric hypertensive Systolic
(Quadriceps, NR/NR NR NR n=26
to the.2018) Squat os (45 +- Blood pressure
buttocks)
against wall 8 years) Diastolic
Shoulder/
Arm/Forearm
Training Men
or (waist
(Rodrigue isometric /Women Endurance
scapular,
z Penaet Test NR/NR NR NR n=97 average Vascular
flexors and
to the.2018) Weight of 19 Peripheral
extenders
Sustained years
arm and
forearm)
Arterial stiffness
Hand/Forearm
Speed of the
eleven
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Rev. Digital Act. Phys. Sport 9(1):e2209. July-December, 2023
The results of these isometric resistance training The physiological adaptations that the body goes
protocols, ERI (Table 2) agree that an exposure of through when exposed to exercise is how, after the
the population to an exercise regimen of between second to fourth week of regular exercise,
3 to 12 weeks and a frequency of 3 to 5 sessions improvements in resistance and strength in physical
per week, which, shows which is optimal to condition are seen. Already in the period from the
maintain and begin to reduce the population's fourth to the eighth week of exercise, improvement in
hypertension levels. According explosive strength and speed begins.
Table 2. Description of intervention methods and results of research on the use of isometric exercises in
populations with high blood pressure.
Author Methods Results Conclusions
Effect: Significant reductions in resting SBP (
−4 ± 5 mmHg), DBP (−3 ± 3 mmHg), and
Resting heart rate, BP, cardiac output, total MAP (−3 ± 3 mmHg) compared to the control Findings suggest that the wall squat provides an
(Wileset peripheral resistance, and stroke volume were condition (P < 0.001). effective method of reducing resting BP, resulting
to the.2017) taken at baseline and after each session. primarily from a reduction in resting heart rate.
Clinically relevant reductions (≥2 mmHg) in
SBP and DBP were recorded in 68 and 71% of
participants, respectively.
Effect: 7 mmHg reduction in SBP (136 ± 12 to
There is a reduction in SBP after 8 weeks of IRT.
129 ± 15; P = 0.04), in the 30% group.
Handgrip at 30% maximal voluntary contraction
significantly reduced SBP and MAP, indicating that
Randomized 2 groups at 30% and 5% of 4 mmHg reductions in TAM (100 ± 8 to 96 ±
(Carlsonet IRT may be an alternative for people who cannot
maximum contraction with isometric handgrip. 11; P = 0.04), in the 30% group.
to the.2016) achieve the current recommendations of 2.5 hours
There were no statistically significant
of weekly aerobic exercise, to control can.
reductions in DBP for the 30% group or any
data for the 5% group.
5
López-Mejía, VA; Christmas Eve-Serna, R.; He rnández-Alvarado, MF; Menu dez-
Ávila, JC; Morales- Hernández, AG: management andhigh blood pressure
Cocontinuation tabla 2
Study carried out in 3 randomized groups of
hypertensive patients. Effect: Aerobic exercise, the criterion d and
IHT (2 contractions of 2 minutes at 30% of to Primary assessment, 24-h systolic to
maximum power). (n=25). ambulatory blood pressure decreased either
Mock grip training, (2 minute contractions at 2 significantly from 126.1 +- 10.1 to 121.2 + - IHT did not reduce BP in hypertensive patients. He
(Pagonas 5% of maximum power). (n=25). to 11.8 mmHg (P = 0.025). The 24-h ambulatoryn Aerobic exercise, even as a strict, uncontrolled n
et al. diastolic blood pressure decreased from either regimen, led to a significant reduction in office n
2017) Aerobic exercise training (n=25). Patients 77.6 +- 8.6 to 75.9 +- 10.9 mmHg, without n and ambulatory BP. he
underwent 24-h ambulatory BP measurement to reaching statistical significance (P = 0.14).
and non-invasive evaluation of arterial and There were no statistically significant and
compliance and systemic vascular resistance to changes in TAS, TDA in the isometric either
before the study and after the study. either exercise, or in the handgrip drill.
period.
Effect: Compared to men, women have yes,
reduced ADR (9.1 ± 0. 5
Participants were randomly assigned into two yes It is concluded that 12 weeks of IHT have reduced
vs. 8.0 ± 0.3 m/s; Control: 8.7 ± 0.5 vs. 8.8 ± 0.5 and
either
TA:Blood pressure,TAS:Systolic Blood Pressure, PAM:Mean arterial pressure,TAD:Diastolic Blood Pressure,VS:Stroke Volume,IC:heart
rate,IRVS:Systemic Vascular Resistance Index,BMI:Body Mass Index,PPS:Sustained Weight Test,PWV:Pulse Wave Velocity,IHT:Isometric
Grip Training,IHG:Isometric grip,IE:isometric training,RMax:Maximum Repetition,IRT: Isometric resistance training.
Thus, it is concluded that the effect of aerobic One of the first articles that analyzes and
exercise is superior to isometric grip strength evaluates the hemodynamic responses of
exercise, IHG, as an antihypertensive treatment and hypertensive participants to isometric exercise
its recommendation should continue, due to its (wall squat) is the following: using this standard
immediate and sustained benefit on BP. Aerobic protocol it is feasible to suggest that similar
exercise induced a post-exercise hypotension effect, responses can be expected, regardless of the
PEH, due to the circadian variation from 4 to isometric training used; it is recommended,
6 mmHg, during waking hours; On the contrary, strongly, a more IHG-based approach obtained
no hypotension effect. OK the evidence when prescribing unsupervised ETI
with Ashet al.(2017), aerobic exercise training to people with suboptimal BP control. In these
reduced resting SBP by 7 mmHg during waking circumstances, an “individualized” ETI
hours, while DBP was not different. In contrast, prescription would be provided for better control
IHG resistance exercise training increased and higher risk patients (Wileset al.2018)
resting DBP by 5 mmHg during waking hours
and 7 mmHg during sleeping hours, while SBP Rodriguez Penaet al.(2018) point out that the
was not different. values of TAS, TAD and TAM rise in all categories
during exercise; diastolic was the one that
showed the greatest increase in both genders, a
Likewise, as mentioned in the following article, fact that is explained by the significant increase in
the information collected and provided in the systemic vascular resistance. In relation to
studies that precede the research with gender, although no statistical differences were
isometric strength protocols lacks data with obtained, the values achieved by women in the
which a comparison can be made with what isometric test were slightly higher than men,
was done with aerobic resistance exercises. , except in the hypertensive group.
demonstrating that grip training
isometric-IHT does not reduce BP in patients On the other hand, the study by Cahu Rodrigueset al.
(2020), indicates
hypertensive patients, on the other hand, aerobic exercise, carried out that
as aTAS and
strict TAD
and have a
uncontrolled
regimen, led to a significant reduction in ambulatorysignificant reduction
BP (Pagonas after isometric grip
et al.2017).
training (IHT); In the same way, it is observed
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Rev. Digital Act. Phys. Sport 9(1):e2209. July-December, 2023
that, compared to men, women reduced ADR of age, showing significant results in the
more; women 9.1 ± 0.5 versus, men 8.0 ± 0.3; reduction of SBP at rest (-4 ± 5mmHg), DBP (-3
Likewise, no significant correlation was ± 5mmHg). The resting values for SBP were
observed between changes in systolic and 126 ± 7 mmHg, before the training phase; with
diastolic blood pressure after IHT and changes SBP at rest post-workout, reducing to 122 ± 8
in arterial stiffness and markers of endothelial mmHg. After the washout period, the control
function. phase began with a baseline value of 125 ± 7
mmHg, for SBP, in these 14 participants. These
Among the studies analyzed, those carried out values are compared to the initial baseline of
and focused on the effects of muscle strength 129 ± 7 mmHg, the post-control phase 128 ± 7
programs stand out, in which 72% of subjects mmHg, and then the post-training values.
were sedentary, a fact that attributes the fourth
cardiovascular risk factor, worldwide and Likewise, Carlsonet al.(2016) show the effects of
represents 9 % of premature deaths, in patients isometric actions on BP in the adult population,
with some cardiovascular disease. 29% of the in nine randomized trials, divided into 6
articles studied the effect of strength training normotensive and 3 hypertensive subjects (223
on sedentary subjects, divided into weekly participants), of which 96 were controls, finding
frequency (2-3 times per week); number of reductions in BP = 6.77 mmHg, between
series (3-4); number of repetitions (6-10), with -7.93 to -5.62; DBP of 3.96 mmHg, between -4.80 to
gradual increase in exercise intensity; exercise - 3.12 and MAP, 3.94 mmHg, between -4.73 to
intensity (50% of 1 Rm), low level loads; rest -3.16. The results show that the effect obtained
interval (1-3 min rest), between series and with isometric exercises is greater than with
recovery (5 min rest interval between exercises) resistance and dynamic strength training,
(Ocampo & Ramírez-Villada, 2018). suggesting that this exercise has the potential
to produce significant BP reductions.
7
López-Mejía, VA; Christmas Eve-Serna, R.; Hernández-Alvarado, MF; Méndez-Ávila,
JC; Morales-Hernández, AG: management of high blood pressure
be a good complement for the control of HTN, creation and innovation of plans that prioritize
because they are a therapeutic measure that non-pharmacological rehabilitation treatments,
reduces costs, is minimally invasive and easy to which improve the activity and quality of life of
apply; At the same time, they have been shown patients.
to significantly maintain and reduce BP better
than with resistance training. Thanks.We thanked the Nursing faculty of the
Autonomous University of Querétaro. Conflict
Due to the above, we consider that the health of interest: The authors declare that there is no
sector can intervene with a battery of isometric conflict of interest. Funding: This project did not
exercises, as a non-pharmacological treatment, receive funding from the public or private
monitoring patients with HTN. In short, it sector.
should be a priority for physical rehabilitation
to increase actions and efforts in
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