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Fetal growth
Ovum – ovulation to fertilization
Zygote – Fertilization to implantation
Embryo – implantation to 5-8 weeks
Fetus – 5-8 weeks to until term
Conceptus Developing of the embryo
A. Fertilization
-Union of a matured egg and a sperm & the product is called a conceptus or zygote.
-Occurs at the distal 3rd of the fallopian tube – the ampulla
two changes that take place in the sperm as it reaches the ovum
1. Capacitation – removal of the protective coating (zona pellucida & corona radiata) of the sperm
2. Acrosome reaction = perforation of the head and release of enzymes (Hyaluronidase)
B. Implantation / Nidation:
- the blastocyst remains free floating in the uterine cavity for 3-5 days & implants in the endometrium 6-
7 days after fertilization.
- as it attaches itself to the wall of the uterus, its trophoblast (layer of blastocyst) cells release enzymes
allowing it to burrow deep into the endometrium resulting in rupture of vessels & bleeding at the
implantation site. “Implantation bleeding”.
>Chorionic villi
• As early as 12 days after fertilization, tiny projections around the zygote, called villi, can be seen.
• They receive rich blood supply. It will later on form the fetal side of the placenta.
• Chronic villi: Trophoblasts two distinct layers:
1. Cytotrophoblast or Langhan’s layer: - inner layer that protects the fetus against syphilis until the
2nd trimester.
2. Syncytiotrophoblast or syncytial layer: - outer layer that produces hormones HCG, HPL. Estrogen
& progesterone.
>Placenta
• Has 20 cotyledons
• Formed from the chorionic villi and decidua basalis.
• Functional at the end of the 2nd month & it reaches maturity at 12 weeks gestation
• Continue to function until the 40 to 41st week.
• Degenerate after the 42nd week making it dangerous
• 2 sides of placenta:
1. Maternal side which is irregular and is divided into subdivisions called cotyledons
2. Fetal side covered by amnion, so it is smooth and shiny
1. Functions of the placenta
1. Respiratory system = exchange of gases
2. Renal system = waste products
3. Gastrointestinal system = nutrients
4. Circulatory system = fetus placental circulation
5. Protective barrier = provides IGG that gives fetus passive immunity
6. Endocrine system = produces hormones HCG, HPL, estrogen, progesterone, relaxin
2. Estrogen - stimulates development of uterine and breast tissues in the mother -
increases vascularity and vasodilation in the villous capillaries
3. Progesterone - after 11 weeks of pregnancy, placenta takes over the production of
progesterone from the corpus luteum
9. Cord insertion:
a. Central insertion – normally, cord is inserted at the center of the fetal surface of
the placenta.
b. Lateral insertion – cord is inserted away from the center of the placenta but not
at its edges.
c. Velamentous insertion – cord is inserted in the membranes about 5 to 10 cm
away from the edge of the placenta.
d. Battledore insertion – cord is inserted at the edge of the placenta
STAGES OF FETAL GROWTH AND DEVELOPMENT
A. Pre-embryonic = first 2 weeks beginning with fertilization
B. Embryonic = weeks 3-8, considered the most critical in fetal stage because of organogenesis.
C. Fetal = weeks 8 to birth
1st Trimester – 12 weeks
2nd Trimester – 13-27 weeks
3rd Trimester - 28-40 weeks
Second trimester
• (16 weeks)
1. Fetal heart sounds audible via fetoscope
2. Lanugo is well formed, liver & pancreas functioning
3. Swallowing reflex,
4. Sex can be determined by ultrasound
5. Quickening felt by a multigravida
• (20 WEEKS)
1. Quickening felt by a primagravida
2. Antibody production is possible
3. Hair forms
4. Meconium present in upper intestine
5. Brown fat
6. Fetal heart audible via stethoscope
7. Vernix caseosa begins to form
• (24 weeks)
1. Passive antibody transfer
2. Active production of lung surfactant begins
3. Eyelids now open
4. Pupils reactive to light
5. Hears in response to sudden sound.
Third Trimester
• (28 weeks)
1. Lung alveoli begins to mature
2. Surfactant present in amniotic fluid
3. Blood vessels of the retina extremely susceptible to damage from high o2 concentrations
• (32 weeks)
1. Subcutaneous fat begins to be deposited (the former “stringy” old man appearance is lost)
2. Fetus is aware of sounds outside the mother’s body
3. Active moro reflex present
4. Birth position (vertex or breech) may be assumed
5. Iron stores
• (36 weeks)
1. Additional amounts of subcataneous fats are deposited
2. Lanugo begins to diminish
3. most babies turn into a vertex or head-down presentation during this month
• (40 weeks)
1. Fetus kicks actively causing discomfort to the mother
2. vernix caseosa is fully formed
3. in primiparas, the fetus lightening in last two weeks
Ultrasound
• Transabdominal UTZ
• full bladder
• client lies on her back
• Transvaginal UTZ
• probe is inserted in the vagina
• lithotomy position
• empty bladder
Nonstress Test
• Measures the response of fetal heart rate to fetal movement
• Tocodynamometer - measure the contraction, tracing for 20 minutes
• Reactive nonstress test normal/negative (2, f heartrate, 15 bpm for 15 sec)
• Nonreactive nonstress test: abnormal
• Unsatisfactory
Special Structures:
Foramen Ovale
▪Connects the left and right atrium
▪Bypassing fetal lungs
▪Obliterated after birth to become fossa ovalis
Umbilical Vein
▪Brings oxygenated blood coming from the placenta to the fetus
▪Becomes ligamentum teres
Umbilical arteries
▪Carry unoxygenated blood from the fetus to placenta
▪Become umbilical ligaments after birth
Ductus venosus
▪Carry oxygenated blood from umbilical vein to IVC
▪Bypassing fetal liver
▪Becomes ligamentum venosum after birth
Ductus arteriosus
▪Carry oxygenated blood from pulmonary artery to aorta
▪Bypassing fetal lungs
▪Becomes ligamentum arteriosum; closes after birth
1. Nulligravida – a woman who has never been pregnant
2. Primigravida – a woman who is pregnant for the first time
3. Multigravida – a woman who has two or more pregnancy
4. Para – number of past pregnancies
5. Nullipara – a woman who has never delivered a fetus that reached the age of viability
6. Primipara – a woman who has completed one pregnancy to viability
7. Multipara – a woman who has completed two or more pregnancy to the age of viability
8. Term infant – an infant born between 38 and 42 weeks of gestation
9. Preterm – an infant born before 38 weeks
10. Post term – an infant born after 42 weeks
11. Live birth – a live birth is recorded when an infant born shows sign of life
12. Parturient – a woman in labor
13. Puerpera – a woman who just delivered (within six weeks after delivery)
14. Low birth weight – < 2500 grams
15. Normal Birth weight – 2500 – 4000 grams
16. Large birth weight - > 4000 grams
SIGNS OF LABOR
1.Uterine contractions – the surest sign that labor has begun is the initiation of effective productive
uterine contractions.
2. If rupture of membranes (rom) is suspected, confirmation can be done by testing the vaginal discharge
with a nitrazine paper. Yellow = acidic. Blue= Alkaline.
3. Show – this is due to pressure of the descending presenting part of the fetus which causes rupture of
minute capillaries in the mucus membrane of the cervix. Blood mixes with mucus when operculum
(mucus plug) is released.
Theories of labor
1. oxytocin stimulation theory
- stimulates the uterine contraction
- oxytocin= contractions and milk ejection
2. uterine strech theory
- hollow muscular organ when strech will contract and empty
3. progesterone deprivation theory
-not enough progesterone (maintains pregnancy)
4. theopry of againg placenta
- BPS biophysical scoring
- prostagalndin- pain and contraction
-prostaglandin can also come from semen
Stages of Labor
First stage- (STAGE OF DILATATION)
➢Latent phase (3cm, short contraction for 20-40 sec, 15-20 intervals)
➢Active phase (4-7cm, moderate, 40-60 sec, 3-5 min) 3Hrs in primipara & 2Hrs in multipara. Give
anesthesia
➢Transition phase (8-10cm, strong, 60-90 sec, 2-3 min)
Second stage (STAGE OF EXPULSION) effaced - (thinning of cervix)
➢Period from full dilatation and cervical effacement to birth of the infant
Third stage (STAGE OF PLACENTAL EXPULSION)
➢Placental separation
➢Placental expulsion
Fourth Stage (STAGE OF PUERPERIUM / STAGE OF VIGILANCE) 3-6 hours for delivery
➢ Stage of recovery
LENGTH OF LABOR
STAGE. PRIMIS MULTIS
1 ST STAGE 10-12 HRS 6-8 HRS
2 ND STAGE 2 HRS 50 MIN AVE. 20 TO 90 MIN AVE.
3 RD STAGE 5 TO 20 MIN 5 TO 20 MIN
4 TH STAGE 2 TO 4 HRS 2 TO 4 HRS
TYPES OF ANESTHESIA
A. Paracervical – transvaginal injection into either side of the cervix. Patient on lithotomy position.
Coupled with a local anesthetic, results in a painless childbirth
B. Pudendal – injection through the sacrospinous ligament into posterior areolar tissues to reduce
perception of pain during second stage & make mother comfortable. Patient is on lithotomy position.
Side effect:
ecchymosis = purplish discoloration of the skin due to blood in the subcutaneous tissues
C. Epidural – injection of local anesthetic at the lumbar level outside the dura mater. Can’t feel from
below abdomen. No pillows for 8-12hrs to avoid headache
CONTRAINDICATIONS OF ENEMA:
A. Malpresentation & position
B. Vaginal bleeding
C. Ruptured bag of waters
D. Crowning
E. Placenta previa
RITGEN’S MANEUVER
• Cover the anus with sterile towel & exert upward & forward pressure on the fetal chin. While
exerting gentle pressure with two fingers on the head to control emerging head. This will not
only support the perineum thus preventing lacerations but will also favor flexion so that the
smallest suboccipitobregmatic diameter of the fetal head is presented.
FORCEP DELIVERY
• Obstetrical forceps are double bladed instruments designed to grasp the fetal head
• The use of forceps requires a fully dilated cervix (10 cm)
TYPES:
1. Outlet forcep - used when the head is visible in the perineum. This is advocated for delivery of
preterm infants.
2. Mid forcep – used when the fetal head is above the ischial spines (rarely used)
CATEGORIES OF LACERATIONS(tahi)
1.First degree – involves the vaginal mucus membranes & skin of the perineum & the fourchette.
2. Second degree – involves not only the vaginal mucus membranes & skin but also the muscles.
3. Third degree – involves not only the rectal sphincter of the rectum, muscles, vaginal mucus
membranes & skin but also the mucus membranes of the rectum
PUERPERIUM / POSTPARTUM
• refers to the six-to-eight-week period after the delivery of the baby.
INVOLUTION
• the return of the reproductive organs to their prepregnant state. (6 weeks
LOCHIA
• Uterine discharge consisting of blood, deciduas, wbc & mucus. Should be moderate in amount
PATTERN OF LOCHIA
1. Rubra = 0-3 days , dark red & moderate in amount, small clots, fleshy stale odor.
2. Serosa = 4 -7 days ; pink or brownish in color, no clots, no odor ( unless poor hygiene)
3. Alba = 1 – 3 weeks; cream to yellowish in color; minimal in amount; no odor; no clots
B. MEMBRANE SPACES
• Suture lines are important because they allow the bones to move and overlap, a process called
molding.
1. Sagittal suture line = the membranous interspace which joins the 2 parietal bones.
2. Coronal suture line = the membranous interspace which joins the frontal bone and the
parietal bones.
3. Lambdoidal suture line
C. FONTANELLES MEMBRANE
• Covered spaces at the junction of the main suture lines:
1. Anterior fontanel = the larger, diamond shaped fontanel which closes between 12 to 18
months in an infant
2. Posterior fontanel = the smaller triangular shaped fontanel which closes between 2-3 months
in the infant. The space between the two fontanelles is referred to as the vertex.
D. MEASUREMENTS
• The shape of the fetal skull causes it to be wider in its anteroposterior (ap) diameter than in its
transverse diameter.
STATION
• Refers to the relationship of the presenting part of the fetus to the level of the ischial spines.
• Station 0 = presenting part is at the level of the ischial spines (synonymous to engagement)
• Station -1 = presenting part is 1cm above the ischial spines
• Station +1 = presenting part is 1cm below the ischial spines
• Station +3 or +4 = the presenting part is at the perineum & can be seen if the vulva is separated;
synonymous to “crowning”.
FETAL LIE/ PRESENTATION
• Is the relationship between the long axis of the fetus to the long axis of the mother
Presenting part
• refers to the fetal part that first enters the maternal pelvis & cover the internal os.
2 kinds of lie
1. Longitudinal lie = long axis of the fetus is parallel to the long axis of the mother.
2. Transverse lie = long axis of the fetus is perpendicular to the long axis of the mother
• causes of transverse lie: 1. multiparity 2. Contracted pelvis 3. Placenta previa
2. Pelvic or breech presentation: 3% - means that either the buttocks or feet are the first body parts to
contact the cervix
Complete breech = (good full flexion)
• Fetus has thighs tightly flexed on the abdomen; both the buttocks & the knees tightly flexed feet
present to the cervix.
Frank breech = (moderate flexion)
• Hips are flexed but the knees are extended to rest on the chest. The buttocks alone present to
the cervix.
Footling (poor flexion)
• Foot present at the introitus. Neither the thighs nor lower legs are flexed.
• Single footling – one leg is extended at the hip & knee & the other leg presents in the introitus.
• Double footling – both legs are unflexed & both feet are the presenting part.
DIVISIONS:
1. False pelvis
• “Superior half”; supports the uterus during the late months of pregnancy & aids in directing the
fetus into the true pelvis for birth.
2. True pelvis
• Inferior half”; formed by the pubes in front, the ilia & the ischia on the sides & the sacrum &
coccyx behind.
RULES
1.NAEGELE’S RULE
• Calculation of expected date of confinement (edc)
• - 3 +7 +1
2. MC DONALD’S RULE
• Estimation of aog in months & weeks by fundic height measurement
• Weeks and days
• 34 weeks & 7 days (36w 7/7)
3. HAASE’S RULE
• ESTIMATION OF FETAL LENGTH
• FIRST HALF OF PREG, SQUARE THE NUMBER OF THE MONTH
• SECOND HALF OF PREG, MULTIPLY THE MONTH BY 5
• 8 months x 5 = 40 CMS length
4. JOHNSON’S RULE
• Estimation of weight in grams
• Fundic height in cm – N X K
• “K” is constant, it is always 155
• “N” is minus 11 if part is not yet engaged(22 below), minus 12 if part is already engaged(23-27)
• 21 – 11 = 10 X 155 = 1,550 GMS
5. BARTHOLOMEW’S RULE
• Estimation of AOG by the relative position of the uterus in the abdominal cavity.
• By the 3rd lunar month, the fundus is palpable slightly above the symphysis pubis
• On the 5th lunar month, the fundus is at the level of the umbilicus
• On the 9th lunar month, the fundus is below the level of the xiphoid process
Maternal Diet and Infant Health
Components of healthy nutrition
• Fluid needs
• Fiber needs
• Foods to avoid
1. Alcohol
2. Caffeine
3. Artificial sweeteners
4. Weight loss diets
Nutritional status
1. Weight gain should be within expected parameters
2. increased nutrient requirements
a. Calories – 300 kcal/d; may need adjustment for prepregnant under/overweight
c. Carbohydrates – needed to prevent unsuitable use of fats/proteins for added energy needs; important
to avoid “empty” calorie sources
d. Proteins to 60 g/d; additional increase for adolescent/multiple pregnancies; efficient use of requires
complete protein (contains all essential amino acids; animal sources) or complemented with other
protein sources, e.g., legumes, grains, nuts
f. Calcium to 1,200/d; best obtained from dairy products; if milk is disliked or poorly tolerated, calcium
supplement may be necessary
g. Sodium – should not be restricted without serious indication; excess should be discouraged