Port said University 2nd Term 2017/2018

Faculty of Nursing ‫الفرقة األولى‬ Course Name: Biochemistry

Final Exam 2018 5/6/2018 Time: One hour

All questions should be answered

Question (I): (7 Marks)
Select and answer the most appropriate answer or completion :

1- Which of the following having proteins with high biological value?

a- Milk b- Zein of maize
c- keratins d- All of the above

2- Increasing of plasma cholesterol above 220mg/dl, this is due to:

a- Diet rich in cabohydrate b- Diet rich in saturated Fatty acids
c- Diabetes mellitus d- All of the above

3- What is a carbohydrate commonly present in dairy products?

a- Maltose b- Isomaltose
c- Lactose d- Sucrose

4- Which of the following vitamins deficiency is delayed eruption of teeth?

a- Vitamin D b- Vitamin A
c- Vitamin E d- Vitamin C

5- The vitamin A is also called as .................... .

a- anti infective factor
b- anti xerophthalmic factor
c) Growth factor
d) All of the above

6- Which of the following vitamins acts as antioxidant.

a- Vitamin C b- Vitamin A
c- Vitamin E d- All of the above

7- Pellagra may result from the deficiency of the following, except:

a- Niacin. b- Pyridoxal phosphate
c- Biotin. d- Tryptophan

8- Alzheimer’s disease is neurologic disorders results from abnormalities in :-

a- Lipids structure. b- carbohydrate structure
c- protein structure . d- None of the above.

9- Which of the following is uncouplers of respiratory chain?

a- Ascorbic acid. b- γ-tocopherols.
c- Calcium d- All of the above.
10- Lactase enzyme deficiencies lead to all the following, except :
a- Diarrhea. b- Increase osmotic pressure.

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 Port said University 2nd Term 2017/2018
Faculty of Nursing ‫الفرقة األولى‬ Course Name: Biochemistry
Final Exam 2018 5/6/2018 Time: One hour

c- Water withdrawn from tissues. d- None of the above.

11- Which of the following vitamin is anti-night blindness:-

a- Vitamin C b- Vitamin A
c- Vitamin E d- Vitamin K

12- Which of the following vitamin is protects against rancidity:

a- Vitamin B6 b- Vitamin B1
c- Vitamin E d- Vitamin K

13- Which of the following vitamin deficiency lead to osteoporosis:

a- Vitamin E b- Vitamin B1
c- Vitamin D d- Biotin

14- Which of the following vitamin produced from intestinal flora:

a- Vitamin C b- Vitamin A
c- Vitamin E d- Vitamin K

1 2 3 4 5 6 7 8 9 10 11 12 13 14

Question (II): (5 Marks)

Put (T) for true statements and (F) for false statements.
1- Lactic acidosis can occur in muscle during rest.

2- Fluoride adding to the blood before measuring blood glucose to activate glycolysis.
3- Favism is Chronic hemolytic anemia if ingestion of fava beans.
4- The Function of liver glycogen is to maintain the blood glucose level during fasting.

5- Fructose is the major energy source for spermatozoa in the seminal vesicle.

6- All vitamin are insoluble in water and not stored.

7- Lactic acidosis arise from oxidation of glucose during severe muscle exercises.
8- Deficiencies in glycolysis associated with hemolytic anemia.
9- Increasing in fat content of stool may be due to errors of lipid digestion and
absorption .
10- Drinking of tea will increase lipolysis.
1 2 3 4 5 6 7 8 9 10

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 Port said University 2nd Term 2017/2018
Faculty of Nursing ‫الفرقة األولى‬ Course Name: Biochemistry
Final Exam 2018 5/6/2018 Time: One hour

f f T T T f T f T f

Question (III): (5 Marks)

Match the number and the lettered items as they best fit together :-

(A)
1- Barbiturate a- sources of NADPH ++H+
2- High doses of aspirin b- sources of ATP
3- Carbon monoxide c- storage in liver and muscle.
4- Lipids d- uncouplers.
5- Glycogen e- lead to hypoxia.
6- HMP shunt f- inhibit ATP synthesis

1 2 3 4 5 6
f d e b c a

(B)

1- Macrocytic anemia a)- Vitamin K2

2- Rickets b)- Vitamin A.
3- Prolonged clotting time c)- Niacin.
4- Night blindness d)- Vitamin D.
e)- Folic Acid.

1 2 3 4

e d a b

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 Port said University 2nd Term 2017/2018
Faculty of Nursing ‫الفرقة األولى‬ Course Name: Biochemistry
Final Exam 2018 5/6/2018 Time: One hour

Question (IV): Answer the following questions (8 Marks)

1- What are importace of ATP?

- Energy required for body activity and anabolic functions.
- Energy required for the live where the depletion of energy lead to death (as in
starvation).
- Regulation of body weight where extra energy lead to obesity with its complication.
- Muscle contraction.
- Nerve conduction.
- Absorption-secretion sodium pump.
- Activation of monosaccharides (glucose to glucose-6-P), fatty acids (to fatty acyl
coA), amino acids and synthesis of cyclic AMP and active methionine.
- Thyroid hormones ( T3,T4) controlled energy released.

What are causes of fatty liver?

This is an accumulation of abnormal amount of fat in the liver for long time which
leads to liver fibrosis & impairment of liver function .
Causes of fatty liver :
I- Overmobilization of fat from extrahepatic tissue to the liver :
1- During high fat diet .
2- Due to excessive lipolysis as in carbohydrate low diet, starvation & diabetes Mellitus.
II- High carbohydrate diet :
On high carbohydrate diet, liver is first saturated with glycogen then any excess
carbohydrate is converted to F.A. (lipogenesis) then to triacylglycerol.
III- Undermobilization of fat from the liver to plasma :
Due to deficiency of any factor essential for plasma lipoproteins formation such as :
1- Decreased synthesis of apoprotein .
2- Failure in formation of phospholipids .
3- Failure in conjugation of the apoprotein with triacylglycerols or phospholipids
4- Failure in secretion of lipoprotein from liver to plasma.
5- Liver poisons : as Ccl4 ,CHcl3 , lead & arsenic .
6- Alcoholism : ethanol stimulates lipogenesis & inhibiting fatty acid oxidation.
7- Deficiency of lipotropic factors :
Lipotropic factors are substances that help the mobilization of fat from the liver.

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 Port said University 2nd Term 2017/2018
Faculty of Nursing ‫الفرقة األولى‬ Course Name: Biochemistry
Final Exam 2018 5/6/2018 Time: One hour

What are biological importance of proteins?

1- Synthesis of tissue proteins so they important for growth
2- Synthesis of cell organells as cell membrane.
3- They regulate the osmotic pressure .
4- Synthesis of enzymes & Heme.
5- Synthesis of milk proteins .
6- Synthesis of proteins hormones
7- Synthesis of plasma proteins e.g albumin & globulins
8- Synthesis of nucleoproteins .
9- Antibodies for immunological reactions.

What is ketosis?
With my best washes ;;;;;;;

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