‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

‫مندوب الدفعة ‪ /‬محمد االشول‬ ‫‪Biochemistry‬‬ ‫جمعت بواسطة ‪/‬‬

‫رئيس اللجنة العلمية ‪ /‬خالد الضياني‬ ‫‪questions‬‬
‫أعضاء اللجنة العلمية للدفعة الثالثة‬
‫د‪ /‬جميلة السمهري‬ ‫طب بشري – جامعة عمران‬
‫تنسيق وطباعة ‪ /‬عبدهللا اللصبي‬
‫‪Biochemistry‬‬
‫‪Department‬‬
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

Q-I- Choose the single best answer (C) Xylulose

for the following statements? 9. Glucose on oxidation does not
1. All the following are essential give
amino acids except : A) Glycoside
a) Threonine (B) Glucosaccharic acid
b) Lysine (C) Gluconic acid
c)Tryptophan (D) Glicuronic acid
d)Alanine 10.The monosaccharide units are
2. Spermatozoa in seminal fluid linked hya(1 → 4) glycosidie
utilizes the following sugar for its linkage in:
metabolism: (A) Maltose
a. Galactose (B) Sucrose
c. Sucrose (C) Cellulose
b. Glucose (D) lactose
d. Fructose
3. Reduction of glucose gives:
2) sorbitol Q2-B- Put true or false?
b) mannitol 1) Amylose is unbranched chains of
c) ribitol D-glucose ( )
4. All the following are 2) oxidation of sugar gives alcohol
Homopolysaccharides except: 3) Arabinose is Keto pentoses ( )
b) cellulose 4) Reduction of sugar gives acid ( )
a) starch 5) Cane sugar is maltose ( )
C)heparin 6) The carbohydrate component of
5. A pentose sugar is RNA and DNA is L-Ribose( )
ATDitydroxyacetune 7) the main sugar of semen is
(B) Ribulase sucrose ( )
IC) Erythrose 8) fructose is ketohexose ( )
(D) Glecose 9) Valine is essential amino acid ( )
6. The general formula of 10) D-Manitol, used in manufacture
polysaccharides of candies ( )
A) (C6H10 OSin Q3- Ilow monosaccharaides are
B) (C6H12 05)n further classifiçd?
C) (COHIO 06)n Q4- What is the medical
D) (C6H10 06)n important of Ribose alcohol?
7. The aldose sugar is Q5-Write about Structural
A) Glycerose funetion of amino acids ?
(B) Ribulose
(C) Erythrulose
(D) Dihydoxyacetone
8. A sugar alcohol is
(B) Trehalose
AJ Mannitol
(D) Atabinose
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

‫اختبار الدفعة الرابعة – طب بشري – جامعة‬ d. Oleic acid

‫عمران‬ 8. The major amino sugar all the
following except :
BIOCHEMISTRY FINAL TERM a) glucosamine
EXAM b) galactosamine
1" year of medicine c) protamine
Q-1-Choose the correct answer 2| Glycosphingolipid is made up
for the following statements? of all the following except;
1. Which deposition results in a) Glucose
cataract? b) Glycerol
a. Glucose c) Sphingosine
b. Galactose d) Fatty acids
c. Sugar alcohols 10. Which of the following is a
d. Sugar amines glycolipid?
2. Cellulose is: a. Cerebroside
a. Complex Lipoprotein b. Plasmalogen
b. Non starch Polysaccharide c. Sphingomyelin
c. Starch Polysaccharide d. Lecithin
d. Complex Glycoprotein 11. Second messenger is
3. Нераrin is а: produced from:
a. Glycosaminoglycan a Phosphatidylinositol
b. Рroteoglycan b. Phosphatidylserine
c. Polysaccharide c. Phosphatidylcholine
d. Carbohydrate d. None of the above
4. Which of the following is not 12. Globosides composed of:
an aldose? a) Ceramide + monosaccharide
a. Glucose b) sphingosine +FA (C18-24)
b. Mannose c) Ceramide + Oligosaccharide
c. Fructose d) Ceramide + short chain fatty
d. Galactose acid
5. Cn(H2O)n is the formula for: 13. Lipoprotein are large
a. Monosaccharide Triglycerides -rich complex are:
b. Disaccharide b) VLDL
c. Polysaccharide a) LDL
d. Oligosaccharide c) HDL
6. Which of the following is d) Chylomicron
enantiomer: 14. Which among the following
a. D-Galactose and L-Glucose is not a saturated fatty acid?
b. d- Galactose and I-Glucose a) Stearic acid
O D-glucose and L-Glucose b) Palmitic
d. D-glucose and l-Glucose c) Linoleic acid
7. Essential fatty acid is/are:
a. Palmitic acid 15. When choline of lecithin is
b. Linoleic acid replaced by ethanolamine the
c. Linolenic acid
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

product is 23. Nucleoside is made up of the

a. Spingomyelin following except:
c. Plasmalogens a. Pyrimidine
c. Cephalin b. Sugar
d. Lysolecithin c. Purine
d. Phosphate
16. In which category keratin 24. All basic amino acids except :
belong : а)Leucine
a) Derived protein d) histidine
c) Simple globular proteins b)arginine
17. Which of the following is a 25. Semi-essential amino acid is:
tripeptide: c) lycine
b) Conjugated proteins a)Arginine
d)Simple fibrous proteins b) glycine
a) ADH d)glutamic acid
c) Oxytocin c) phenylalanine
d) Methionine enkephalin 26. Glucose on oxidation does not
b) Glutathione give:
18. Casein, the milk protein is: a) Glycoside
a) Nucleoprotein b) Glucosaccharic acid
c) Phosphoprotein c) Gluconic acid
b) Chromoprotein d) Glucuronic acid
d) Glycoprotein 27. Number of stereoisomers of
19. Which of the following is not a glucose is:
nitrogenous base? а) 4
a. Adenine b) 8
b. Guanosine c) 16
c. Cytosine d) None of these
20. Which is not found in DNA: 28. which of the following sugar
d. Thymine acids are produced by oxidation
a. Adenine of glucose aldehyde group:
b. Thymine a)Gluconic acid
c. Guanine b)glucuronic acid
d. Uracil Glucaric acid
21. The two strands of DNA are d)all above
held together by: 29. he following properties are
b) Covalent bond common for both glucose and
a) Hydrogen bond ribose:
c)lonic interaction a Both are aldoses
d) peptide bond b)both are found in DNA
22. Proteins seen in nucleic acid d) both are found in disaccharides
are called; c)Both are ketoses
a. Nucleotides 30. sphingosin is a component of :
b. Histones b)gangliosides
c. Apoproteins a)Cerebrosides
d. Glycoproteins
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

d) all of them
c)Sphingomyline

Put true or false

1. Amylose is unbranched chains of D-glucose ()

2. Peptides are compounds formed of more than 50 amino ( )
3. Albumin is important because it contain all non-essential amino acids ()
4. Arabinose is Keto pentoses ( )
5. Elastin is a globular proteins ()
6. Sphingomyelins on hydrolysis yield Glycerol, Sphingosine choline and fatty
acids ( )
7. In cephalin choline is replaced by Ethanolamine ( )
8. Oleic acid is not essential fatty acid ( )
9. Lecithin is not a phospholipid ( )
10. a -D-glucose and B-D-glucose are related by Anomerism ( )
11. Starch and glycogen are polymers of a -D-glucose ( )
12. A polymeric unit of starch which has a branched structure is Amylopectin
13. Spermatozoa in seminal fluid utilizes glucose for its metabolism ( )
14. A GAG is an branched heteropolysaccharide ( )
15. The repeating unit in hyaluronic acid is Glucuronic acid and galactose (
16. Table sugar is Sucrose ()
17. Dextrins as glucose in postage stamp and envelope adhesive ( )
18. Glutathione is a Tripeptide
19. bond present in the primary structure of protein is hydrogen bond ( )
20. In denaturation of proteins, the bond which is not broken is Peptide bond
21. Agar is polymer of galactose ()
22. Type of sugar in glycoprotein is polysaccharides ( )
23. dihydroxy acetone have one asymmetric carbon ( )
24. RNA molecules Found in the Nucleus & the Cytoplasm ( )
25. Translation takes place in the nucleus ( )
26. The genetic code consists of 64 triplets of nucleotides ( )
27. Neutral fats is phospholipids ( )
28. Triglycerides Provide lung alveoli with surfactants
29. The precursor of steroid hormones is cholesterol
30. LDL is called good cholesterol ( )
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

‫تجميع أعضاء اللجنة العلمية للدفعة الثالثة‬ ‫اختبار نهاية الترم الثاني لسنة ثانية‬
‫ جامعة عمران‬- ‫طب بشري‬

MCQ

1. Chylomicron, intermediate 6. All function of antioxidant

density lipoproteins (IDL), low ecxpect...
density lipoproteins (LDL) and A) vitamin E
very low density lipoproteins B) vitamin D
(VLDL) all are serum C) vitamin K
lipoproteins. What is the correct D) selenium
ordering of these particles from
the lowest to the greatest density? 7. The number of amino acids in
(A) LDL, IDL, VLDL, pro insulin is
Chylomicron (A) 51 (B) 86
(B) Chylomicron, VLDL, IDL, (C) 109 (D) 132
LDL LDL
(C) VLDL, IDL, LDL, 8. Anti-egg white injury factor is
Chylomicron a. pyridoxine
(D) Chylomicron, IDL, VLDL, b. Biton
LDL c. Thiamin
2. Cyclic GMP acts as the second d. Liponic acid
messenger for
(A) Nerve growth factor 9. . Epinephrine decreases
(B) Atrial natriuretic factor (A) Glycogenesis
(C) Epinephrine (B) Glycogenolysis
(D) Norepinephrine (C) Gluconeogenesis
(D) Lipolysis
3. Which of the following is not a
nitrogenous base: 10. Which of the following
A. Adenine hormone is a peptide of less than
B. Cytosine ten amino acids?
D. Guanosine (A) Insulin
E. Thymine (B) Growth hormone
(C) Oxytocin
4. Selenium cofactor in enzyme (D) Parathyroid hormone
(a). glutathione peroxidase
(b). cytochrome oxidase 11. Refsum’s disease results from
(c). cytochrome reductase a defect in the following pathway
(d). Oxanthin oxidase except
(A) Alpha-oxidation of fatty acids
5. Cortisol is syntheses (B) Beta-oxidation of fatty acids
in (C) Gamma-oxidation of fatty acids
(a). zona glumerulosa (D) Omega-oxidation of fatty acids
(b). zona fasciculata
(c). zona reticularis 12. Carnitine is synthesized from
(d). chromaphil cells (A) Lysine and methionine
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

(B) Glycine and arginine 19. what's the enzyme deficiency

(C) Aspartate and glutamate produce lactic acid :
(D) Proline and hydroxyproline a) Riboflavin
b) Thiamine
13. Which of the following c) Niacin
contributes nitrogen atoms to d) Pantothenic acid
both purine and pyrimidine
rings? 20. Nitric oxide is working by
(A) Aspartate which mechanism :
(B) Carbamoyl phosphate a) cAMP
(C) CO2 b) cGMP
(D) Glutamine c) phospholipase

14. The amino acid containing an 21. a non-peptide among the

indole ring: following is :
(A) Tryptophan (B) Arginine a) antidiuretic hormone
(C) Threonine (D) Phenylalanine b) Insulin
c) ACTH
15. Histamine is formed from d) Thyrotropin releasing hormone
histidine by
(A) Deamination 22. what is the amino acid that is
(B) Dehydrogenation precursor cysteine ?
(C) Decarboxylation a) leucin
(D) Carboxylation b) Metheionin
c) Glutamine
16. of the following are required d) Thyrotropin releasing hormone
for synthesis of glutamine except
(A) Glutamate 23. Which of the following is
(B) Ammonia required as a reductant factor for
(C) Pyridoxal phosphate anabolic reactions:
(D) ATP
a) NADH
17. post translation vitamine b) NADPH
reduced agent hydroxyproline ; c) FADH2
proline is d) FMNH2
a) vit.C
b) vit.E
c) vit.D
d) vit.K

18. Apolipoprotein B-100 is

present in
(A) Chylomicrons
(B) VLDL only
(C) LDL only
(D) VLDL and LDL
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

Put true or false

1- All amino acids are transamination ( )

2- Arginine succinate is part of urea cycle ( )
3- Selenium is a co-factor for glutamine synthase ( )
4- Prolactin is positively regulated by TRH secretion ( )
5- FSH stimulate producing testosterone ( )
6- alkaptonuria occurs due to defect in tyrosine transferase ( )
7- phenylketonuria occurs due to defect in tyrosine decarboxylase ( )

Fill the blanks below :

1- ………………. Form of vitamin A has a role in vision .
2- Alkaptonuria caused by deficiency ………………….
3- Hormonal action on target tissue depend on
4- Triacylglycerol transport mainly between tissue …………………..
5- Vitamin K involved in ………………. Of glutamic acid of inactive clotting
factor.
6- Amino acids forming creatinine phosphate ……………,…………..,…………….
7- Remove the amino acids by transamination to …………… formed by
enzymes ………………………… & ………….. coenzymes ……………..
8- Somatostatin is produced ……………………………………….
9- ANP has 2nd messenger as …………………………..
10- The second messenger for PTH is……………………
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

‫نماذج اختبارات جامعة ذمار‬

‫ جميلة السمهري‬/‫د‬

Q1 Answer the following question:

(a) Write a short note on the role vitamin C & vitamin K including their chemical
structures.
(b) Give the chemical structures of three phospholipids & give the biomedical role
of each one.
(c) Write a short note on the types of ………..metabolism
(d) Write a short note on arachidonic acids derivatives, show the chemical
structure & the importance of each one. Show hoe dose aspirin kills pain.
Q2 fill in the blanks
(a) The secondary structure of proteins means …………………………………..
(b) The structural formula of the amino acid asparagine is …………….. & its
molecular formula is ………………………………..
(c) The compound 2,3-bisphosphoglycerate (BPG) is important to ……………….
(d) Hemoglobin & myoglobin are similar each other in ……………….. ,
……………… & …………………
(e) The role of DNA is ……………….
(f) Steroids play many physiological important roles such as ………………. &
……………..& …………….
(g) The chemical structure of adenosine 5-Triphosphate (ATP) is
……………………..
(h) At its isoelectric PH (PI), an amino acids ……………………………
(i) The R group of Histidine is ……………………………….
(j) Hemoglobin is colored because of
…………………………………………………..
(k) After releasing O2 at the tissues, hemoglobin transports …………………. &
……………. to the lungs.
(l) Cholesterol is a precursor for ………………………
(m) Many sugars have physiological importance such as …………………… &
…………………..
(n) Lecithins are made of choline & ……………………………
(o) ……………………. Is a form of vitamin A that has a role in vision.
(p) Vitamin K is involved in ……………….. of glutamic acid residues of the inactive
clotting factor.
(q) The form of iron which absorbed from GI tract is ………………….
(r) In wounds healing, the trace element involved is ………………………..
(s) Water soluble hormones have cell surface receptors are ……………………….
(t) The hormonal action on the target organs depends ……………………………..
(u) Steroid cholesterol is a precursor of ……………… , …………………. , ……………
, …………….
 ‫اللجنة العلمية للدفعة الثالثة – طب بشري – جامعة عمران‬

Q3 choose the correct answer:

1- All the following vitamins act as antioxidant agent except:
A) Vitamin C
B) Vitamin D
C) Vitamin E
2- Anti-egg white injury factor vitamin refer to:
A) Vitamin B7
B) Vitamin B6
C) Vitamin B12
3- A hormone responsible for reabsorption of sodium & excretion of potassium is:
A) Cortisone
B) Testosterone
C) Aldosterone
D) Vasopressin
4- Low plasma calcium:
a) Triger the release of PTH
b) Inhibit the release of PTH
c) No effect on PTH
5- One of the following is not the form of vitamin K:
A) Phylloguinone
B) Menaguinone
C) Minadioone
D) Ubiguinone
6- The trace element which has antioxidant property is:
a) Fluoride
b) Selenium
c) Molybdenum
d) Manganese
7- Which of the following doesn’t secrete stored hormones
a) Ovary
b) Testes
c) Adrenal medulla
d) Placenta
8- One of the following fatty acid derivatives don’t contain a ring in its structure:
a) Prostaglandin
b) Leukotriene
c) Thromboxane
d) Phosphoridylinostiol
9- Lipids are classified as:
a) Amphipathic
b) Soluble
c) Non-soluble
d) Heterocyclic compounds containing aromatic.

Q4 Put True or False

1- Asparagine is an amino acids contains carbonyl group & two amino groups ( )
2- Oxygenation of hemoglobin is accompanied by layer conformational changes ( )
3- Prostaglandins a local hormone, include (PGS), (PG1S) & (TXS) ( )
4- Maltose & lactose are disaccharides formed of CHO ( )

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