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Nucleus
Pulposus
Anatomy Review
• Intervertebral Disc
- Absorbs the stress
and shock the body
incurs during
movement
- Prevents the
vertebrae from
grinding against one
another
Anatomy Review
• Annulus Fibrosus
- A sturdy tire-like structure that encases a gel-like
center, the nucleus pulposus.
- Enhances the spine’s rotational stability and helps
to resist compressive stress.
• Nucleus Pulposus
- Center portion of each intervertebral disc
- Filled with a gel-like elastic substance
- Transmits stress and weight from vertebra to
vertebra.
Each disc is made up of two parts:
annulus fibrosus & nucleus pulposus.
Alternative Names
• Lumbar radiculopathy;
• Cervical radiculopathy;
• Herniated intervertebral disk;
• Prolapsed intervertebral disk;
• Slipped disk;
• Ruptured disk
Herniated Nucleus Pulposus:
• A slipped disk along the spinal cord.
• Advanced age
• History of back trauma
• Male
• Congenital conditions
Precipitating FACTORS
• Sedentary lifestyle
• Sitting without lumbar support
• Cigarette smoking
• Chronic coughing
• Strenuous activities
CLINICAL MANIFESTATIONS
• Arm muscle weakness
- Use of electron
microscope through
a small incision to
remove a portion of
the HNP that is
displaced
Chemonucleolysis
- involves the injection
of an enzyme (called
chymopapain) into
the herniated disk to
dissolve the
protruding gelatinous
substance.