Msds

Hitachi Medical Systems America, Inc.
1959 Summit Commerce Park

Twinsburg, Ohio 44087-2371
Tel.: 330.425.1313
Fax: 330.425.1410
 Test Phantoms
Material Safety Data Sheets for Altaire
The information presented below and on the following pages is in response to your
inquiry regarding the solutions used in the imaging performance phantoms for the
Hitachi Altaire Magnetic Resonance Imager. Enclosed please find Material Safety Data
Sheets (MSDS) for the following reagents:
• NaCl Sodium Chloride
• NiCl2 • 6H2O Nickel Chloride Hexahydrate
Concentrations of these reagents in the phantoms are according to the following chart:
Capacity
Phantom Purpose NiCl2 • 6H2O NaCl
(liters)
A Extremity 1 10.5 mmol/l 0.15 w/v%
B Knee 2 10.5 mmol/l 0.15 w/v%
C Head 5 10.5 mmol/l 0.15 w/v%
D Body (M) 10 10.5 mmol/l 0.42 w/v%
E Body (L) 20 10.5 mmol/l 0.15 w/v%
F Body (XL) 30 10.5 mmol/l 0.15 w/v%
G TMJ 0.1 10.5 mmol/l 0.15 w/v%
Fisher Scientific furnished the following MSDS information. See their disclaimer at the
bottom of page 13.
Table of Contents
Sodium Chloride.............................................................................................................. 2
Nickel (II) Chloride Hexahydrate ..................................................................................... 8
Page: 1 of 13
FISHER SCIENTIFIC ACC# 21105 Sodium Chloride
Material Safety Data Sheet

Sodium Chloride
Section 1 - Chemical Product and Company Identification

MSDS Name: Sodium Chloride
Catalog Numbers: AC424290030, S641212, S641350LB, S641500, S71988, S71989,
S71989-1, S78446, S78449, S78449-1, BP358 1, BP358 10, BP358 212, BP358-1, BP358-
212, BP3581, BP35810, BP3581000, BP358212, BW13550350, BW1355350, BW13555350,
NC9468610, NC9516271, NC9519034, NC9534701, NC9566889, NC9607345, NC9648474,
NC9683841, NC9755215, S271 1, S271 10, S271 3, S271 350LB, S271 50, S271 500,
S271-1, S271-10, S271-3, S271-350L, S271-350LB, S271-50, S271-500, S2711, S27110,
S2713, S271350L, S271350LB, S27150, S271500, S27150LC, S640 10, S640 3, S640 50,
S640 500, S640-10, S640-3, S640-50, S640-500, S64010, S64010001, S64010002,
S64010LC, S6403, S640350KG, S64050, S640500, S641-212, S641-350LB, S641-500,
S641350LCBLC, S641P350LB, S671 10, S671 3, S671 500, S671-10, S671-3, S671-500,
S67110, S67110LC, S6713, S671500, S71989-2, S719891, S719892, S784491, WESS2713,
XX64125LB, XXB64017.5KG, XXBP358350LB, XXS27120KG, XXS271250LBX, XXS64010KG,
XXS64085KG
Synonyms: Common salt; Halite; Rock salt; Saline; Salt; Sea salt; Table salt.
Company Identification:
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
CAS# Chemical Name Percent EINECS/ELINCS

7647-14-5 Sodium chloride ca.100 231-598-3
Page: 2 of 13
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Appearance: colorless or white. Caution! May cause respiratory tract irritation. May cause
eye and skin irritation. May cause digestive tract irritation with nausea, vomiting, and
diarrhea.
Target Organs: Blood, lungs, male reproductive system.
Potential Health Effects

Eye: May cause eye irritation.
Skin: May cause skin irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Ingestion of
large amounts may cause nausea and vomiting, rigidity or convulsions. Continued exposure
can produce coma, dehydration, and internal organ congestion.
Inhalation: May cause respiratory tract irritation.
Chronic: No information found.
Section 4 - First Aid Measures

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper
and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical
aid. Wash mouth out with water.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other
symptoms appear.
Notes to Physician: None
Section 5 - Firefighting Measures

General Information: Wear appropriate protective clothing to prevent contact with skin
and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with
thermal decomposition products. Substance is noncombustible.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
Page: 3 of 13
Section 6 - Accidental Release Measures

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container.
Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions.
Section 7 - Handling and Storage

Handling: Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest
or inhale.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection

Engineering Controls: Good general ventilation should be sufficient to control airborne
levels. Facilities storing or utilizing this material should be equipped with an eyewash facility
and a safety shower.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Sodium chloride none listed none listed none listed
OSHA Vacated PELs: Sodium chloride: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear safety glasses with side shields.
Skin: Wear appropriate gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: A NIOSH/MSHA approved air purifying dust or mist respirator or European
Standard EN 149.
Page: 4 of 13
Section 9 - Physical and Chemical Properties

Physical State: Solid
Appearance: colorless or white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 2575 deg F
Freezing/Melting Point:1474 deg F
Decomposition Temperature:Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: (estimated) Health: 1; Flammability: 0; Reactivity: 0
Explosion Limits, Lower:Not available.
Upper: Not available.
Solubility: Soluble in water
Specific Gravity/Density:2.165
Molecular Formula:NaCl
Molecular Weight:58.4428
Section 10 - Stability and Reactivity

Chemical Stability: Stable.
Conditions to Avoid: High temperatures.
Incompatibilities with Other Materials: Reacts with most nonnoble metals such as iron
or steel, building materials (such as cement), bromine, or trifluoride. Potentially explosive
reaction with dichloromaleic anhydride + urea. Electrolysis of mixtures with nitrogen
compounds may form explosive nitrogen trichloride.
Hazardous Decomposition Products: Toxic fumes of sodium oxide.
Hazardous Polymerization: Has not been reported.
Page: 5 of 13
Section 11 - Toxicological Information

RTECS#:
CAS# 7647-14-5: VZ4725000
LD50/LC50:
CAS# 7647-14-5:
Oral, mouse: LD50 = 4 gm/kg;
Oral, rat: LD50 = 3 gm/kg;<BR.
Carcinogenicity:
CAS# 7647-14-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information reported.
Teratogenicity: An experimental teratogen.
Reproductive Effects: Human reproductive effects by intraplacental route: terminates
pregnancy. Experimental reproductive effects.
Neurotoxicity: No information reported.
Mutagenicity: Human mutation data reported.
Other Studies: No information reported.
Section 12 - Ecological Information

Ecotoxicity: No information found.
Environmental Fate: No information reported.
Physical/Chemical: No information found
Other: No information found
Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local hazardous waste
regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
Canada
US DOT IATA RID/ADR IMO
TDG
No No
Shipping Name: information information
available. available.
Hazard Class:
UN Number:
Packing Group:
Page: 6 of 13
Section 15 - Regulatory Information
US FEDERAL
TSCA
CAS# 7647-14-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 7647-14-5: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA. None
of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 7647-14-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 7647-14-5: 0
Canada
CAS# 7647-14-5 is listed on Canada's DSL/NDSL List.
This product has a WHMIS classification of D2B.
CAS# 7647-14-5 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
Section 16 - Additional Information

MSDS Creation Date: 7/12/1999
Revision #2 Date: 8/02/2000
Page: 7 of 13
FISHER SCIENTIFIC ACC# 16310 Nickel (II) Chloride Hexahydrate

Nickel (II) Chloride Hexahydrate

MSDS Name: Nickel (II) Chloride Hexahydrate
Catalog Numbers: S80104, S80104-1, N53 500, N53-500, N53500, N54 10, N54 250, N54
3, N54 500, N54-10, N54-250, N54-3, N54-500, N5410, N54250, N543, N54500, S801041
Synonyms: Nickelous Chloride; Nickel Dichloride.
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410

7791-20-0 NICKEL(II) CHLORIDE HEXAHYDRATE >97% unlisted
Hazard Symbols: T
Risk Phrases: 25 20

EMERGENCY OVERVIEW
Appearance: green. Warning! May cause allergic skin reaction. Toxic. Harmful if
swallowed. Contact with skin causes irritation and possible burns, especially if the skin is
wet or moist. May cause severe skin irritation and possible burns. May cause respiratory
and digestive tract irritation. May cause cancer based on animal studies. Potential cancer
hazard.
Target Organs: Respiratory system.
Eye: May cause eye irritation and possible burns.
Skin: Contact with skin causes irritation and possible burns, especially if the skin is wet or
moist. May cause severe irritation and possible burns. May cause dermatitis. Causes "nickel
itch" which is a dermatitis resulting from sensitization to nickel, which is characterized by
skin eruptions, followed by discrete ulcers that may discharge and become crusted, or by
eczema.
Ingestion: Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting
and diarrhea.
Inhalation: Inhalation of a mist of this material may cause respiratory tract irritation.
Chronic: Prolonged or repeated skin contact may cause sensitization dermatitis and
possible destruction and/or ulceration. May cause respiratory tract cancer. Symptoms of
overexposure to nickel can cause sensitization, dermatitis, allergic asthma and pneumonitis.
Page: 8 of 13

and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes
closed.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of
milk or water. Never give anything by mouth to an unconscious person. Get medical aid
immediately.
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately.
If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use
mouth-to-mouth respiration.
Notes to Physician: Treat symptomatically and supportively.

General Information: As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water
runoff can cause environmental damage. Dike and collect water used to fight fire. During a
fire, irritating and highly toxic gases may be generated by thermal decomposition or
combustion.
Extinguishing Media: Substance is noncombustible; use agent most appropriate to
extinguish surrounding fire.

Reduce airborne dust and prevent scattering by moistening with water. Clean up spills
immediately, observing precautions in the Protective Equipment section. Avoid generating
dusty conditions. Carefully scoop up and place into appropriate disposal container.

Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before
reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid
contact with skin and eyes. Avoid ingestion and inhalation.

Engineering Controls: Facilities storing or utilizing this material should be equipped with
an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
NICKEL(II) CHLORIDE
none listed none listed none listed
HEXAHYDRATE
Page: 9 of 13
OSHA Vacated PELs: NICKEL(II) CHLORIDE HEXAHYDRATE: No OSHA Vacated PELs are
listed for this chemical.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European
Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator
when necessary.

Appearance: green
Odor: odorless
pH: 4.0 (aqueous sol)
Vapor Pressure: 1 mm Hg @1140F
Evaporation Rate:Negligible
Freezing/Melting Point:Not available.
Autoignition Temperature: Noncombustible.
Flash Point: Noncombustible.
Solubility: Soluble.
Specific Gravity/Density:3.55 (water=1)
Molecular Formula:NiCl2.6H2O

Chemical Stability: Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid: Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials: Strong acids, peroxides, potassium.
Hazardous Decomposition Products: Hydrogen chloride, nickel oxide.
Page: 10 of 13

RTECS#:
CAS# 7791-20-0: QR6480000
LD50/LC50:
CAS# 7791-20-0:
Oral, rat: LD50 = 157 mg/kg;<BR.
Carcinogenicity:
CAS# 7791-20-0:
ACGIH: A5 - Not Suspected as a Human Carcinogen (listed as ** undefined **).
California: carcinogen; initial date 10/1/89 (listed as ** undefined **).
NIOSH: occupational carcinogen (listed as ** undefined **)
NTP: Suspect carcinogen (listed as ** undefined **).
OSHA: Possible select carcinogen (listed as ** undefined **).
IARC: Group 2B carcinogen (listed as ** undefined **).
Epidemiology: IARC Group 2B: Proven animal carcinogenic substance of pote ntial
relevance to humans. IARC Group 2B: No data availa ble on human carcinogenicity,
however sufficient evi dence of carcinogenicity in animals. Epidemiological studi es have
shown an increased incidence of cancers among nickel refinery workers. An increased
incidence of lung and nasal cavity cancers has been noted among women in nickel smelters
and refineries.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: Cytogenetic Analysis: mouse mammary gland 800umol/L. Sister Chromatid
Exchange: hamster fibroblast 32mg/L.
Other Studies: See actual entry in RTECS for complete information.

Ecotoxicity: No information available.
Physical/Chemical: No information available.
Other: None.

Page: 11 of 13
Canada
TDG
TOXIC
Shipping SOLIDS,ORGANIC,N.O.S. NICKEL
Name: (CONTAINS NICKEL CHLORIDE
CHLORIDE)
Hazard Class: 6.1 6.1(9.2)
UN Number: UN2811 UN9139
Packing
III III
Group:

US FEDERAL
TSCA
CAS# 7791-20-0 is not on the TSCA Inventory. It is a hydrate and exempt from TSCA
Inventory requirements (40CFR720.3(u)(2)).
Chemical Test Rules
Section 12b
SARA
Section 302 (RQ)
Section 302 (TPQ)
SARA Codes
CAS # 7791-20-0: acute, chronic.
Section 313
This material contains NICKEL(II) CHLORIDE HEXAHYDRATE (listed as ** undefined **),
97%, (CAS# 7791-20-0) which is subject to the reporting requirements of Section 313 of
SARA Title III and 40 CFR Part 373.
Clean Air Act:
Clean Water Act:
OSHA:
Page: 12 of 13
STATE
Hazard Symbols:
T
Risk Phrases:
R 25 Toxic if swallowed. R 20 Harmful by inhalation.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
CAS# 7791-20-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list. This product has a
WHMIS classification of D1B, D2A.
Exposure Limits
CAS# 7791-20-0: OEL-ARAB Republic of Egypt:TWA 0.1 mg(Ni)/m3 OEL-AU
STRALIA:TWA 1 mg(Ni)/m3 OEL-BELGIUM:TWA 1 mg(Ni)/m3 (insoluble compou
nds) OEL-BELGIUM:TWA 1 mg(Ni)/m3 OEL-CZECHOSLOVAKIA:TWA 0.05 mg(Ni)/
m3;STEL 0.25 mg(Ni)/m3 OEL-DENMARK:TWA 0.05 mg(Ni)/m3;Carcinogen OEL
-DENMARK:TWA 1 mg(Ni)/m3 (insoluble compounds) OEL-FINLAND:TWA 0.1 mg
(Ni)/m3;Carcinogen OEL-FINLAND:TWA 0.1 mg(Ni)/m3;Skin;CAR (insoluble
compounds) OEL-FRANCE:TWA 1 mg(Ni)/m3 OEL-GERMANY;Carcinogen OEL-HU
NGARY:STEL 0.005 mg(Ni)/m3;CAR (insoluble compounds) OEL-HUNGARY:STEL
0.005 mg(Ni)/m3;Carcinogen OEL-JAPAN:TWA 1 mg(Ni)/m3;Carcinogen OEL
-THE NETHERLANDS:TWA 0.1 mg(Ni)/m3 OEL-THE NETHERLANDS:TWA 1 mg(Ni)/m
3 (insoluble compounds) OEL-THE PHILIPPINES:TWA 1 mg(Ni)/m3 OEL-RUSS
IA:STEL 0.05 mg(Ni)/m3 OEL-SWEDEN:TWA 0.5 mg(Ni)/m3 OEL-SWITZERLAND:
TWA 0.5 mg(Ni)/m3 (insoluble compounds) OEL-SWITZERLAND:TWA 0.5 mg(Ni
)/m3;Carcinogen JAN9 OEL-THAILAND:TWA 1 mg(Ni)/m3 OEL-UNITED KINGDOM
:TWA 0.5 mg(Ni)/m3 (insoluble compounds) OEL-UNITED KINGDOM:TWA 1 mg(
Ni)/m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL
IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV

The information above is believed to be accurate and represents the best information currently available to us. However,
we make no warranty of merchantability or any other warranty, express or implied, with respect to such information,
and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability
of the information for their particular purposes. In no way shall Fisher be liable for any claims, losses, or damages of
any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever
arising, even if Fisher has been advised of the possibility of such damages.
Page: 13 of 13
Tel.: 330.425.1313
Fax: 330.425.1410
Reference: Material Safety Data Sheets for Phantom Solutions
inquiry regarding the solutions used in the imaging performance phantoms for the
MRP-5000, MRP-7000, or the AIRIS/AIRIS II Magnetic Resonance Imagers. Enclosed
please find Material Safety Data Sheets (MSDS) for the following reagents:
• NiSO4 • 6H2O Nickel Sulfate Hexahydrate
Concentrations of these reagents in the phantoms are according to the following chart:
Capacity
Phantom Purpose NiCl2 • 6H2O NiSO4 • 6H2O NaCl
(liters)
SNR #1 Knee 1 18mmol/l – 0.1 w/v%
SNR #2 Neck 3 18mmol/l – 0.7 w/v%
SNR #3 Head 5 18mmol/l – 0.1 w/v%
SNR #4 Body 10 18mmol/l – 0.5 w/v%
SNR #5 Extra Lg. Body 30 18mmol/l – 1.0 w/v%
FOV FOV 0.7 – 3mmol/l –
Fisher Scientific furnished the following MSDS information. See their disclaimer at the
bottom of page 19.
Table of Contents
Sodium Chloride.............................................................................................................. 2
Nickel (II) Chloride Hexahydrate ..................................................................................... 8
Nickel (II) Sulfate Hexahydrate...................................................................................... 14
Page: 1 of 19
FISHER SCIENTIFIC Sodium Chloride

Sodium Chloride
ACC# 21105
MSDS Name: Sodium Chloride
Catalog Numbers: AC424290030, S641212, S641350LB, S641500, S71988, S71989,
S71989-1, S78446, S78449, S78449-1, BP358 1, BP358 10, BP358 212, BP358-1, BP358-
212, BP3581, BP35810, BP3581000, BP358212, BW13550350, BW1355350, BW13555350,
NC9468610, NC9516271, NC9519034, NC9534701, NC9566889, NC9607345, NC9648474,
NC9683841, NC9755215, S271 1, S271 10, S271 3, S271 350LB, S271 50, S271 500,
S271-1, S271-10, S271-3, S271-350L, S271-350LB, S271-50, S271-500, S2711, S27110,
S2713, S271350L, S271350LB, S27150, S271500, S27150LC, S640 10, S640 3, S640 50,
S640 500, S640-10, S640-3, S640-50, S640-500, S64010, S64010001, S64010002,
S64010LC, S6403, S640350KG, S64050, S640500, S641-212, S641-350LB, S641-500,
S641350LCBLC, S641P350LB, S671 10, S671 3, S671 500, S671-10, S671-3, S671-500,
S67110, S67110LC, S6713, S671500, S71989-2, S719891, S719892, S784491, WESS2713,
XX64125LB, XXB64017.5KG, XXBP358350LB, XXS27120KG, XXS271250LBX, XXS64010KG,
XXS64085KG
Synonyms: Common salt; Halite; Rock salt; Saline; Salt; Sea salt; Table salt.
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410

7647-14-5 Sodium chloride ca.100 231-598-3
Page: 2 of 19
EMERGENCY OVERVIEW
Appearance: colorless or white. Caution! May cause respiratory tract irritation. May cause
eye and skin irritation. May cause digestive tract irritation with nausea, vomiting, and
diarrhea.
Target Organs: Blood, lungs, male reproductive system.

Skin: May cause skin irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal irritation. Ingestion of
large amounts may cause nausea and vomiting, rigidity or convulsions. Continued exposure
can produce coma, dehydration, and internal organ congestion.
Inhalation: May cause respiratory tract irritation.
Chronic: No information found.

and lower eyelids. Get medical aid.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical
aid. Wash mouth out with water.
respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other
symptoms appear.
Notes to Physician: None

General Information: Wear appropriate protective clothing to prevent contact with skin
and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with
thermal decomposition products. Substance is noncombustible.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
Page: 3 of 19

Clean up spills immediately, observing precautions in the Protective Equipment section.
Avoid generating dusty conditions.

Handling: Use with adequate ventilation. Minimize dust generation and accumulation.
Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Do not ingest
or inhale.

Engineering Controls: Good general ventilation should be sufficient to control airborne
levels. Facilities storing or utilizing this material should be equipped with an eyewash facility
and a safety shower.
Exposure Limits
Sodium chloride none listed none listed none listed
OSHA Vacated PELs: Sodium chloride: No OSHA Vacated PELs are listed for this chemical.
Eyes: Wear safety glasses with side shields.
Respirators: A NIOSH/MSHA approved air purifying dust or mist respirator or European
Standard EN 149.
Page: 4 of 19

Appearance: colorless or white
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Evaporation Rate:Not available.
Freezing/Melting Point:1474 deg F
Autoignition Temperature: Not available.
Flash Point: Not available.
Solubility: Soluble in water
Specific Gravity/Density:2.165
Molecular Formula:NaCl

Chemical Stability: Stable.
Conditions to Avoid: High temperatures.
Incompatibilities with Other Materials: Reacts with most nonnoble metals such as iron
or steel, building materials (such as cement), bromine, or trifluoride. Potentially explosive
reaction with dichloromaleic anhydride + urea. Electrolysis of mixtures with nitrogen
compounds may form explosive nitrogen trichloride.
Hazardous Decomposition Products: Toxic fumes of sodium oxide.
Page: 5 of 19

RTECS#:
CAS# 7647-14-5: VZ4725000
LD50/LC50:
CAS# 7647-14-5:
Oral, mouse: LD50 = 4 gm/kg;
Oral, rat: LD50 = 3 gm/kg;<BR.
Carcinogenicity:
CAS# 7647-14-5: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information reported.
Teratogenicity: An experimental teratogen.
Reproductive Effects: Human reproductive effects by intraplacental route: terminates
pregnancy. Experimental reproductive effects.
Neurotoxicity: No information reported.
Mutagenicity: Human mutation data reported.
Other Studies: No information reported.

Ecotoxicity: No information found.
Physical/Chemical: No information found
Other: No information found

Canada
TDG
No No
Shipping Name: information information
available. available.
Hazard Class:
UN Number:
Packing Group:
Page: 6 of 19
US FEDERAL
TSCA
CAS# 7647-14-5 is listed on the TSCA inventory.
Chemical Test Rules
Section 12b
SARA
Section 302 (RQ)
Section 302 (TPQ)
SARA Codes
CAS # 7647-14-5: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
Clean Water Act:
OSHA:
STATE
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
CAS# 7647-14-5: 0
Canada
CAS# 7647-14-5 is listed on Canada's DSL/NDSL List.
This product has a WHMIS classification of D2B.
Exposure Limits

Page: 7 of 19
FISHER SCIENTIFIC Nickel (II) Chloride Hexahydrate

Nickel (II) Chloride Hexahydrate
ACC# 16310
MSDS Name: Nickel (II) Chloride Hexahydrate
Catalog Numbers: S80104, S80104-1, N53 500, N53-500, N53500, N54 10, N54 250, N54
3, N54 500, N54-10, N54-250, N54-3, N54-500, N5410, N54250, N543, N54500, S801041
Synonyms: Nickelous Chloride; Nickel Dichloride.
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410

7791-20-0 NICKEL(II) CHLORIDE HEXAHYDRATE >97% unlisted
Hazard Symbols: T
Risk Phrases: 25 20

EMERGENCY OVERVIEW
Appearance: green. Warning! May cause allergic skin reaction. Toxic. Harmful if
swallowed. Contact with skin causes irritation and possible burns, especially if the skin is
wet or moist. May cause severe skin irritation and possible burns. May cause respiratory
and digestive tract irritation. May cause cancer based on animal studies. Potential cancer
hazard.
Eye: May cause eye irritation and possible burns.
Skin: Contact with skin causes irritation and possible burns, especially if the skin is wet or
moist. May cause severe irritation and possible burns. May cause dermatitis. Causes "nickel
itch" which is a dermatitis resulting from sensitization to nickel, which is characterized by
skin eruptions, followed by discrete ulcers that may discharge and become crusted, or by
eczema.
Ingestion: Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting
and diarrhea.
Inhalation: Inhalation of a mist of this material may cause respiratory tract irritation.
possible destruction and/or ulceration. May cause respiratory tract cancer. Symptoms of
overexposure to nickel can cause sensitization, dermatitis, allergic asthma and pneumonitis.
Page: 8 of 19

closed.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse.
immediately.
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately.
If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use
mouth-to-mouth respiration.

combustion.

Reduce airborne dust and prevent scattering by moistening with water. Clean up spills
immediately, observing precautions in the Protective Equipment section. Avoid generating
dusty conditions. Carefully scoop up and place into appropriate disposal container.

Page: 9 of 19

Engineering Controls: Facilities storing or utilizing this material should be equipped with
an eyewash facility and a safety shower. Use adequate ventilation to keep airborne
concentrations low.
Exposure Limits
NICKEL(II) CHLORIDE
HEXAHYDRATE
OSHA Vacated PELs: NICKEL(II) CHLORIDE HEXAHYDRATE: No OSHA Vacated PELs are
EN166.
when necessary.

Appearance: green
Odor: odorless
pH: 4.0 (aqueous sol)
Vapor Pressure: 1 mm Hg @1140F
Freezing/Melting Point:Not available.
Autoignition Temperature: Noncombustible.
Flash Point: Noncombustible.
Solubility: Soluble.
Molecular Formula:NiCl2.6H2O
Page: 10 of 19

Conditions to Avoid: Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials: Strong acids, peroxides, potassium.
Hazardous Decomposition Products: Hydrogen chloride, nickel oxide.

RTECS#:
CAS# 7791-20-0: QR6480000
LD50/LC50:
CAS# 7791-20-0:
Carcinogenicity:
CAS# 7791-20-0:
ACGIH: A5 - Not Suspected as a Human Carcinogen (listed as ** undefined **).
Epidemiology: IARC Group 2B: Proven animal carcinogenic substance of pote ntial
relevance to humans. IARC Group 2B: No data availa ble on human carcinogenicity,
however sufficient evi dence of carcinogenicity in animals. Epidemiological studi es have
shown an increased incidence of cancers among nickel refinery workers. An increased
incidence of lung and nasal cavity cancers has been noted among women in nickel smelters
and refineries.
Reproductive Effects: No information available.
Mutagenicity: Cytogenetic Analysis: mouse mammary gland 800umol/L. Sister Chromatid
Exchange: hamster fibroblast 32mg/L.
Other Studies: See actual entry in RTECS for complete information.

Ecotoxicity: No information available.
Other: None.
Page: 11 of 19

Canada
TDG
TOXIC
Shipping SOLIDS,ORGANIC,N.O.S. NICKEL
Name: (CONTAINS NICKEL CHLORIDE
CHLORIDE)
Hazard Class: 6.1 6.1(9.2)
UN Number: UN2811 UN9139
Packing
III III
Group:

US FEDERAL
TSCA
Chemical Test Rules
Section 12b
SARA
Section 302 (RQ)
Section 302 (TPQ)
SARA Codes
Section 313
This material contains NICKEL(II) CHLORIDE HEXAHYDRATE (listed as ** undefined **),
Page: 12 of 19
Clean Air Act:
Clean Water Act:
OSHA:
STATE
Hazard Symbols:
T
Risk Phrases:
R 25 Toxic if swallowed. R 20 Harmful by inhalation.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
CAS# 7791-20-0: No information available.
Canada
Exposure Limits
CAS# 7791-20-0: OEL-ARAB Republic of Egypt:TWA 0.1 mg(Ni)/m3 OEL-AU
STRALIA:TWA 1 mg(Ni)/m3 OEL-BELGIUM:TWA 1 mg(Ni)/m3 (insoluble compou
nds) OEL-BELGIUM:TWA 1 mg(Ni)/m3 OEL-CZECHOSLOVAKIA:TWA 0.05 mg(Ni)/
m3;STEL 0.25 mg(Ni)/m3 OEL-DENMARK:TWA 0.05 mg(Ni)/m3;Carcinogen OEL
-DENMARK:TWA 1 mg(Ni)/m3 (insoluble compounds) OEL-FINLAND:TWA 0.1 mg
(Ni)/m3;Carcinogen OEL-FINLAND:TWA 0.1 mg(Ni)/m3;Skin;CAR (insoluble
compounds) OEL-FRANCE:TWA 1 mg(Ni)/m3 OEL-GERMANY;Carcinogen OEL-HU
NGARY:STEL 0.005 mg(Ni)/m3;CAR (insoluble compounds) OEL-HUNGARY:STEL
0.005 mg(Ni)/m3;Carcinogen OEL-JAPAN:TWA 1 mg(Ni)/m3;Carcinogen OEL
-THE NETHERLANDS:TWA 0.1 mg(Ni)/m3 OEL-THE NETHERLANDS:TWA 1 mg(Ni)/m
3 (insoluble compounds) OEL-THE PHILIPPINES:TWA 1 mg(Ni)/m3 OEL-RUSS
IA:STEL 0.05 mg(Ni)/m3 OEL-SWEDEN:TWA 0.5 mg(Ni)/m3 OEL-SWITZERLAND:
TWA 0.5 mg(Ni)/m3 (insoluble compounds) OEL-SWITZERLAND:TWA 0.5 mg(Ni
)/m3;Carcinogen JAN9 OEL-THAILAND:TWA 1 mg(Ni)/m3 OEL-UNITED KINGDOM
:TWA 0.5 mg(Ni)/m3 (insoluble compounds) OEL-UNITED KINGDOM:TWA 1 mg(
Ni)/m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL

Page: 13 of 19
FISHER SCIENTIFIC Nickel (II) Sulfate Hexahydrate

Nickel (II) Sulfate Hexahydrate
ACC# 16410
MSDS Name: Nickel (II) Sulfate Hexahydrate
Catalog Numbers: S76472, S76475, N72 3, N72-3, N723, N73 100, N73 500, N73-100,
N73-500, N73100, N73500
Synonyms: Nickeous Sulfate Crystal; Single Nickel Salt; Sulfuric Acid Nickel (II) Salt.
Fisher Scientific
1 Reagent Lane
Fair Lawn, NJ 07410

10101-97-0 NICKEL(II) SULFATE HEXAHYDRATE >98% unlisted
Hazard Symbols: XN N
Risk Phrases: 22 40 42/43 50/53

EMERGENCY OVERVIEW
Appearance: blue-green. Warning! May cause allergic skin reaction. Harmful if
swallowed. May cause eye and skin irritation. May cause respiratory and digestive tract
irritation. May cause cancer based on animal studies.

Skin: Causes skin irritation. May cause severe irritation and possible burns. May cause
dermatitis.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation: Dust is irritating to the respiratory tract. Inhalation of vapor may cause
respiratory tract irritation.
possible destruction and/or ulceration. May cause respiratory tract cancer.
Page: 14 of 19

closed.
immediately.
respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-
mouth respiration.

combustion. Vapors may be heavier than air. They can spread along the ground and collect
in low or confined areas.

Spills/Leaks: Wash area with soap and water. Wear a self contained breathing apparatus
and appropriate Personal protection. (See Exposure Controls, Personal Protection section).
Avoid generating dusty conditions. Carefully scoop up and place into appropriate disposal
container. Provide ventilation.

Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away
from incompatible substances. Keep away from strong acids.
Page: 15 of 19

Engineering Controls: Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
NICKEL(II) SULFATE
HEXAHYDRATE
OSHA Vacated PELs: NICKEL(II) SULFATE HEXAHYDRATE: No OSHA Vacated PELs are
EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
when necessary.

Appearance: blue-green
Odor: None reported
pH: 4.5 in solution.
Vapor Pressure: Negligible
Vapor Density: 9.1
Boiling Point: 103 deg C
Freezing/Melting Point:53 deg C
Decomposition Temperature:280 deg C
Autoignition Temperature: Noncombustible
Flash Point: Noncombustible
Solubility: 625g/L @20C in water.
Molecular Formula:NiSO4.6H2O
Page: 16 of 19

Conditions to Avoid: Ignition sources, excess heat, strong acids.
Incompatibilities with Other Materials: Strong acids, strong oxidizing agents.
Hazardous Decomposition Products: Oxides of sulfur, irritating and toxic fumes and
gases, nickel oxide.

RTECS#:
CAS# 10101-97-0: QR9600000
LD50/LC50:
CAS# 10101-97-0:
Carcinogenicity:
CAS# 10101-97-0:
ACGIH: A4 - Not Classifiable as a Human Carcinogen (listed as ** undefined **).
Epidemiology: No information available.
Reproductive Effects: Paternal Effects: intraperitoneal-rat TDLo=403mg/kg.
Mutagenicity: Please refer to RTECS QR9600000 for mutation data and references.
Other Studies: None.

Ecotoxicity: Prawn (salt water) LC50=13.9ppm/48H Rainbow trout (fresh water)
TLm=160ppm/48H
Environmental Fate: Nickel is very mobile in aquatic environment and shows potential for
bioaccumulation.
Other: None.

Page: 17 of 19
Canada
TDG
No
NICKEL
Shipping Name: information
SULFATE
available.
Hazard Class: 9.2
UN Number: UN9141
Packing Group: III
REGULATED
Additional Info: LIMIT
230KG

US FEDERAL
TSCA
Chemical Test Rules
Section 12b
SARA
Section 302 (RQ)
Section 302 (TPQ)
SARA Codes
Section 313
This material contains NICKEL(II) SULFATE HEXAHYDRATE (listed as ** undefined **),
Clean Air Act:
Clean Water Act:
Page: 18 of 19
OSHA:
STATE
Hazard Symbols:
XN N
Risk Phrases:
R 22 Harmful if swallowed. R 40 Possible risks of irreversible effects. R 42/43 May cause
sensitization by inhalation and skin contact. R 50/53 Very toxic to aquatic organisms; may
cause long-term adverse effects in the aquatic environment.
Safety Phrases:
S 22 Do not breathe dust. S 36/37 Wear suitable protective clothing and gloves. S 60 This
material and/or its container must be disposed of as hazardous waste. S 61 Avoid release to
the environment. Refer to special instructions/Safety data sheets.
CAS# 10101-97-0: 2
Canada
Exposure Limits
CAS# 10101-97-0: OEL-ARAB Republic of Egypt:TWA 0.1 mg(Ni)/m3 OEL-A
USTRALIA:TWA 1 mg(Ni)/m3 OEL-BELGIUM:TWA 1 mg(Ni)/m3 (insoluble compo
unds) OEL-BELGIUM:TWA 1 mg(Ni)/m3 OEL-CZECHOSLOVAKIA:TWA 0.05 mg(Ni)
/m3;STEL 0.25 mg(Ni)/m3 OEL-DENMARK:TWA 0.05 mg(Ni)/m3;Carcinogen OE
L-DENMARK:TWA 1 mg(Ni)/m3 (insoluble compounds) OEL-FINLAND:TWA 0.1 m
g(Ni)/m3;Carcinogen OEL-FINLAND:TWA 0.1 mg(Ni)/m3;Skin;CAR (insoluble
compounds) OEL-FRANCE:TWA 1 mg(Ni)/m3 OEL-GERMANY;Carcinogen OEL-H
UNGARY:STEL 0.005 mg(Ni)/m3;CAR (insoluble compounds) OEL-HUNGARY:STE
L 0.005 mg(Ni)/m3;Carcinogen OEL-JAPAN:TWA 1 mg(Ni)/m3;Carcinogen OE
L-THE NETHERLANDS:TWA 0.1 mg(Ni)/m3 OEL-THE NETHERLANDS:TWA 1 mg(Ni)/
m3 (insoluble compounds) OEL-THE PHILIPPINES:TWA 1 mg(Ni)/m3 OEL-RUS
SIA:STEL 0.05 mg(Ni)/m3 OEL-SWEDEN:TWA 0.5 mg(Ni)/m3 OEL-SWITZERLAND
:TWA 0.5 mg(Ni)/m3 (insoluble compounds) OEL-SWITZERLAND:TWA 0.5 mg(N
i)/m3;Carcinogen JAN9 OEL-THAILAND:TWA 1 mg(Ni)/m3 OEL-UNITED KINGDO
M:TWA 0.5 mg(Ni)/m3 (insoluble compounds) OEL-UNITED KINGDOM:TWA 1 mg
(Ni)/m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL

The information above is believed to be accurate and represents the best information currently available to us. However,
we make no warranty of merchantability or any other warranty, express or implied, with respect to such information,
and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability
of the information for their particular purposes. In no way shall Fisher be liable for any claims, losses, or damages of
any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever
arising, even if Fisher has been advised of the possibility of such damages.
Page: 19 of 19
Tel.: 330.425.1313
Fax: 330.425.1410
Material Safety Data Sheets for ACR Phantoms
inquiry regarding the solutions used in the imaging performance phantoms for the ACR
phantoms used with Hitachi Magnetic Resonance Imagers. Enclosed please find
Material Safety Data Sheets (MSDS) for the following reagents:
The phantom has <11 grams of Nickel Chloride Hexahydrate and approximately 17
grams of Sodium Chloride in 3.8 liters of water solution.
! NOTICE
Nickel Chloride is a toxic substance and a suspected

carcinogen. See enclosed Material Safety Data Sheet.
! NOTICE
Keep the phantom in a controlled temperature environment,

ideally between 60 and 80 degrees F. This unit may break open if
subjected to extremes of temperature.
Please retain all original packing and store the phantom in those materials.
Sigma-Aldrich furnished the following MSDS information.
Table of Contents
NICKEL(II) CHLORIDE HEXAHYDRATE........................................................................ 2
SODIUM CHLORIDE ...................................................................................................... 6
Page: 1 of 9
SIGMA-ALDRICH Cat #223387 NICKEL(II) CHLORIDE HEXAHYDRATE
M A T E R I A L S A F E T Y D A T A S H E E T
NICKEL(II) CHLORIDE HEXAHYDRATE
Aldrich Chemical Co., Inc.

1001 West St. Paul
Milwaukee, WI 53233 USA
Tel: 414-273-3850
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -

CATALOG #: 223387
NAME: NICKEL(II) CHLORIDE HEXAHYDRATE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 7791-20-0
MF: CL2NI
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
TOXIC
MAY CAUSE CANCER.
TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN.
MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT.
TARGET ORGAN(S):
LUNGS
DO NOT BREATHE DUST.
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
KEEP CONTAINER TIGHTLY CLOSED IN A COOL WELL-VENTILATED PLACE.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES.
IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS
AMOUNTS OF WATER.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
NONCOMBUSTIBLE.
USE EXTINGUISHING MEDIA APPROPRIATE TO SURROUNDING FIRE CONDITIONS.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
Page: 2 of 9
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -

EVACUATE AREA.
WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
SAFETY SHOWER AND EYE BATH.
USE ONLY IN A CHEMICAL FUME HOOD.
DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
TOXIC.
CARCINOGEN.
IRRITANT.
SENSITIZER.
KEEP TIGHTLY CLOSED.
HYGROSCOPIC
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
GREEN CRYSTALS
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
INCOMPATIBILITIES
PEROXIDES
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
HYDROGEN CHLORIDE GAS
NICKEL/NICKEL OXIDES
Page: 3 of 9
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -

ACUTE EFFECTS
HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
CAUSES DERMATITIS.
MAY CAUSE ALLERGIC RESPIRATORY REACTION.
EXPOSURE CAN CAUSE:
GASTROINTESTINAL DISTURBANCES
CHRONIC EFFECTS
CARCINOGEN.
TARGET ORGAN(S):
LUNGS
RTECS #: QR6480000
NICKEL(II) CHLORIDE, HEXAHYDRATE (1:2:6)
TOXICITY DATA
ORL-RAT LD50:105 MG/KG RPTOAN 32,102,1969
IPR-MUS LD50:48 MG/KG AEPPAE 244,17,1962
IVN-DOG LD50:40 MG/KG EQSSDX 1,1,1975
TARGET ORGAN DATA
SENSE ORGANS AND SPECIAL SENSES (OTHER OLFACTION EFFECTS)
BEHAVIORAL (SOMNOLENCE)
GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA)
EFFECTS ON NEWBORN (VIABILITY INDEX)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
THE MATERIAL SHOULD BE DISSOLVED IN 1) WATER; 2) ACID SOLUTION OR 3)
OXIDIZED TO A WATER-SOLUBLE STATE. PRECIPITATE THE MATERIAL AS THE
SULFIDE, ADJUSTING THE PH OF THE SOLUTION TO 7 TO COMPLETE PRE-
CIPITATION. FILTER THE INSOLUBLES AND DISPOSE OF THEM IN A HAZARDOUS-
WASTE SITE. DESTROY ANY EXCESS SULFIDE WITH SODIUM HYPOCHLORITE.
NEUTRALIZE THE SOLUTION BEFORE FLUSHING DOWN THE DRAIN.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT ALDRICH CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
EUROPEAN INFORMATION
CAUTION: SUBSTANCE NOT YET FULLY TESTED.
TOXIC
R 45
MAY CAUSE CANCER.
R 23/24/25
TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
R 36/37/38
R 42/43
MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT.
S 22
S 45
IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
Page: 4 of 9
S 36/37/39
WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTECTION.
S 3/7/9
KEEP CONTAINER TIGHTLY CLOSED IN A COOL WELL-VENTILATED PLACE.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
ACGIH TLV-TWA 0.1 MG(NI)/M3 DTLVS* TLV/BEI,1999
IARC CANCER REVIEW:ANIMAL LIMITED EVIDENCE IMEMDT 49,257,1990
MSHA STANDARD-AIR:TWA 1 MG(NI)/M3
DTLVS* 3,178,1971
OSHA PEL (GEN INDU):8H TWA 1 MG(NI)/M3
CFRGBR 29,1910.1000,1994
OSHA PEL (CONSTRUC):8H TWA 1 MG(NI)/M3
CFRGBR 29,1926.55,1994
OSHA PEL (SHIPYARD):8H TWA 1 MG(NI)/M3
CFRGBR 29,1915.1000,1993
OSHA PEL (FED CONT):8H TWA 1 MG(NI)/M3
CFRGBR 41,50-204.50,1994
OEL-ARAB REPUBLIC OF EGYPT: TWA 0.1 MG(NI)/M3, JAN1993
OEL-AUSTRALIA: TWA 1 MG(NI)/M3, JAN1993
OEL-BELGIUM: TWA 1 MG(NI)/M3 (INSOLUBLE COMPOUNDS), JAN1993
OEL-DENMARK: TWA 0.1 MG(NI)/M3, JAN1999
OEL-FINLAND: TWA 0.1 MG(NI)/M3, SKIN, CARCINOGEN, JAN1999
OEL-GERMANY: CARCINOGEN, JAN1999
OEL-HUNGARY: STEL 0.005 MG(NI)/M3, CARCINOGEN (INSOLUBLE COMPOUNDS),
JAN1993
OEL-THE PHILIPPINES: TWA 1 MG(NI)/M3, JAN1993
OEL-POLAND: MAC(TWA) 0.25 MG(NI)/M3, JAN1999
OEL-RUSSIA: STEL 0.05 MG(NI)/M3, JAN1993
OEL-SWEDEN: NGV 0.1 MG(NI)/M3, CARCINOGEN, JAN1999
OEL-SWITZERLAND: MAK-W 0.05 MG(NI)/M3, JAN1999
OEL-SWITZERLAND: MAK-W 0.5 MG(NI)/M3, CARCINOGEN, JAN1999
OEL-THAILAND: TWA 1 MG(NI)/M3, JAN1993
OEL-UNITED KINGDOM: LTEL 0.5 MG(NI)/M3 (INSOLUBLE COMPOUNDS), JAN1993
OEL-UNITED KINGDOM: LTEL 1 MG(NI)/M3, JAN1993
OEL IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV;
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV
NIOSH REL TO NICKEL, INORGANIC-AIR:10H CA TWA 0.015 MG(NI)/M3
NIOSH* DHHS #92-100,1992
NOES 1983: HZD X4330; NIS 5; TNF 366; NOS 9; TNE 10406; TFE 3890
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, OCTOBER 2000
U.S. INFORMATION
THIS PRODUCT IS SUBJECT TO SARA SECTION 313 REPORTING REQUIREMENTS.
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1999 SIGMA-ALDRICH CO.
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
Page: 5 of 9
SIGMA-ALDRICH Cat #S9625 SODIUM CHLORIDE
M A T E R I A L S A F E T Y D A T A S H E E T
SODIUM CHLORIDE
Sigma Chemical Co.

P.O. Box 14508
St. Louis, MO 63178 USA
Tel: 314-771-5765
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -

CATALOG #: S9625
NAME: SODIUM CHLORIDE SIGMA GRADE
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
CAS #: 7647-14-5
MF: CLNA
EC NO: 231-598-3
SYNONYMS
COMMON SALT * DENDRITIS * EXTRA FINE 200 SALT * EXTRA FINE 325 SALT *
HALITE * H.G. BLENDING * NATRIUMCHLORID (GERMAN) * PUREX * ROCK SALT *
SALINE * SALT * SEA SALT * TABLE SALT * TOP FLAKE * USP SODIUM
CHLORIDE * WHITE CRYSTAL *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
IRRITANT
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
WEAR SUITABLE PROTECTIVE CLOTHING.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS
AMOUNTS OF WATER.
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY
RUBBER GLOVES.
SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL.
AVOID RAISING DUST.
VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
REFER TO SECTION 8.
Page: 6 of 9
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -

SAFETY SHOWER AND EYE BATH.
MECHANICAL EXHAUST REQUIRED.
WASH THOROUGHLY AFTER HANDLING.
AVOID CONTACT WITH EYES, SKIN AND CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
NIOSH/MSHA-APPROVED RESPIRATOR.
COMPATIBLE CHEMICAL-RESISTANT GLOVES.
CHEMICAL SAFETY GOGGLES.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
APPEARANCE AND ODOR
SOLID.
PHYSICAL PROPERTIES
MELTING POINT: 801 C
VAPOR PRESSURE: 1 MMHG
SPECIFIC GRAVITY: 2.165
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
STABILITY
STABLE.
INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
SODIUM/SODIUM OXIDES
HYDROGEN CHLORIDE GAS
HAZARDOUS POLYMERIZATION
WILL NOT OCCUR.
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
ACUTE EFFECTS
CAUSES SKIN IRRITATION.
MAY BE HARMFUL IF ABSORBED THROUGH THE SKIN.
CAUSES EYE IRRITATION.
MAY BE HARMFUL IF INHALED.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER
RESPIRATORY TRACT.
MAY BE HARMFUL IF SWALLOWED.
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
RTECS #: VZ4725000
SODIUM CHLORIDE
IRRITATION DATA
SKN-RBT 50 MG/24H MLD BIOFX* 20-3/1971
SKN-RBT 500 MG/24H MLD 28ZPAK -,7,1972
EYE-RBT 100 MG MLD BIOFX* 20-3/1971
EYE-RBT 100 MG/24H MOD 28ZPAK -,7,1972
EYE-RBT 10 MG MOD TXAPA9 55,501,1980
Page: 7 of 9
TOXICITY DATA
ORL-MAN LDLO:1 GM/KG MACPAJ 65,1587,1990
ORL-RAT LD50:3 GM/KG TXAPA9 20,57,1971
IHL-RAT LC50:>42 GM/M3/1H BIOFX* 20-3/1971
ORL-MUS LD50:4 GM/KG FRPPAO 27,19,1972
IPR-MUS LD50:2602 MG/KG COREAF 256,1043,1963
SCU-MUS LD50:3 GM/KG ARZNAD 7,445,1957
IVN-MUS LD50:645 MG/KG ARZNAD 7,445,1957
ICV-MUS LD50:131 MG/KG TYKNAQ 27,131,1980
SKN-RBT LD50:>10 GM/KG BIOFX* 20-3/1971
TARGET ORGAN DATA
SENSE ORGANS AND SPECIAL SENSES (OTHER EYE EFFECTS)
BEHAVIORAL (SOMNOLENCE)
BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
BEHAVIORAL (CHANGE IN MOTOR ACTIVITY)
BEHAVIORAL (MUSCLE CONTRACTION OR SPASTICITY)
CARDIAC (OTHER CHANGES)
ENDOCRINE (ESTROGENIC)
MATERNAL EFFECTS (OVARIES, FALLOPIAN TUBES)
MATERNAL EFFECTS (OTHER EFFECTS ON FEMALE)
EFFECTS ON FERTILITY (PRE-IMPLANTATION MORTALITY)
EFFECTS ON FERTILITY (POST-IMPLANTATION MORTALITY)
EFFECTS ON FERTILITY (ABORTION)
EFFECTS ON EMBRYO OR FETUS (FETOTOXICITY)
EFFECTS ON EMBRYO OR FETUS (FETAL DEATH)
SPECIFIC DEVELOPMENTAL ABNORMALITIES (MUSCULOSKELETAL SYSTEM)
NUTRITIONAL AND GROSS METABOLIC (CHANGES IN: NA)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
(RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
Page: 8 of 9
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -

EUROPEAN INFORMATION
IRRITANT
R 36/37/38
S 26
IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
WATER AND SEEK MEDICAL ADVICE.
S 36
WEAR SUITABLE PROTECTIVE CLOTHING.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC 54,7740,1989
NOHS 1974: HZD 68880; NIS 265; TNF 63391; NOS 163; TNE 630453
NOES 1983: HZD E0256; NIS 1; TNF 403; NOS 5; TNE 4029; TFE 2015
NOES 1983: HZD 68880; NIS 336; TNF 69628; NOS 211; TNE 1743954; TFE
817249
EPA GENETOX PROGRAM 1988, NEGATIVE: IN VITRO CYTOGENETICS-NONHUMAN;
SPERM MORPHOLOGY-MOUSE
EPA GENETOX PROGRAM 1988, INCONCLUSIVE: MAMMALIAN MICRONUCLEUS
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
EPA TSCA SECTION 8(E) RISK NOTIFICATION, 8EHQ-0892-9201
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, OCTOBER 2000
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1999 SIGMA-ALDRICH CO.
LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY
Page: 9 of 9

Msds

Uploaded by

Document Information

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Msds

Uploaded by

Copyright:

Available Formats

Hitachi Medical Systems America, Inc.

1959 Summit Commerce Park

Material Safety Data Sheet

Section 1 - Chemical Product and Company Identification

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS

Section 3 - Hazards Identification

Potential Health Effects

Section 4 - First Aid Measures

Section 5 - Firefighting Measures

Section 6 - Accidental Release Measures

Section 7 - Handling and Storage

Section 8 - Exposure Controls, Personal Protection

Section 9 - Physical and Chemical Properties

Section 10 - Stability and Reactivity

Section 11 - Toxicological Information

Section 12 - Ecological Information

Section 13 - Disposal Considerations

Section 14 - Transport Information

Section 15 - Regulatory Information

Section 16 - Additional Information

Material Safety Data Sheet

Section 1 - Chemical Product and Company Identification

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS

Section 3 - Hazards Identification

Section 4 - First Aid Measures

Section 5 - Firefighting Measures

Section 6 - Accidental Release Measures

Section 7 - Handling and Storage

Section 8 - Exposure Controls, Personal Protection

Section 9 - Physical and Chemical Properties

Section 10 - Stability and Reactivity

Section 11 - Toxicological Information

Section 12 - Ecological Information

Section 13 - Disposal Considerations

Section 14 - Transport Information

Section 15 - Regulatory Information

Section 16 - Additional Information

Reference: Material Safety Data Sheets for Phantom Solutions

Material Safety Data Sheet

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS

Section 3 - Hazards Identification

Potential Health Effects

Section 4 - First Aid Measures

Section 5 - Firefighting Measures

Section 6 - Accidental Release Measures

Section 7 - Handling and Storage

Section 8 - Exposure Controls, Personal Protection

Section 9 - Physical and Chemical Properties

Section 10 - Stability and Reactivity

Section 11 - Toxicological Information

Section 12 - Ecological Information

Section 13 - Disposal Considerations

Section 14 - Transport Information

Section 15 - Regulatory Information

Section 16 - Additional Information

Material Safety Data Sheet

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS

Section 3 - Hazards Identification

Section 4 - First Aid Measures