Secretory

function of the
Golgi apparatus
 Content

About the golgi apparatus

Structure of Golgi
Secretory function of Golgi
Sources of information
Abot Golgi
The Golgi apparatus, often referred to as
the Golgi complex or Golgi body, is a
cellular organelle found in eukaryotic cells.
Named after the Italian scientist Camillo
Golgi who first identified it in 1898, this
structure plays a crucial role in the
processing, sorting, and modification of
proteins and lipids.
Cisternae: The fundamental building block of the Golgi apparatus is
the cisternae. These are flattened membrane structures arranged in
stacks. Each cisterna plays a unique role in the processing and
sorting of proteins.
Vesicles: Vesicles, small bubbles pinched off from the cisternae,
carry processed proteins for transport to their designated locations.

Structure of
These vesicles can travel both within the cell and towards the cell
membrane for secretion.
Dictyosomes: Dictyosomes consist of groups of cisternae organized

Golgi
into a cohesive complex. They play a crucial role in the transport and
processing of proteins, coordinating the activities of cisternae within
the Golgi apparatus.
Membrane Transitions: The structure of the Golgi apparatus
includes membrane transitions that connect cisternae. These
transitions not only facilitate membrane flow but also regulate the
transport processes within the apparatus.
Signaling Proteins: The Golgi apparatus structure also involves
various signaling proteins that regulate its functions. These proteins
act as keys, opening and closing different membrane pores during
the transport process.
 Protein Glycosylation:
Secretory One of the pivotal roles of the Golgi
apparatus is protein glycosylation—a
function of process where carbohydrates are
added to proteins. This modification
Golgi is critical for the functional diversity
of proteins and their subsequent
transport to specific cellular
destinations.
Vesicle Formation and Sorting:
The Golgi apparatus serves as a
bustling center for vesicle
formation and sorting. It carefully
packages proteins into vesicles,
each designated for a specific
target—be it lysosomes for
degradation or secretory vesicles
for extracellular transport.
Oligosaccharide Processing:
Within the Golgi, oligosaccharides
are meticulously processed,
impacting the stability and
functionality of glycoproteins. This
process not only influences cellular
signaling but also determines the
fate of proteins in the secretory
pathway.
Quality Control Mechanisms:
Ensuring the fidelity of protein
processing, the Golgi employs
stringent quality control mechanisms.
Misfolded proteins are identified and
either corrected or targeted for
degradation, preventing the release of
malfunctioning proteins into the
cellular milieu.
Sources of information
Structure of the Golgi Apparatus
1. Mollenhauer, Hannes H., and Jurgen Morre. "The Golgi
Apparatus: Structure and Function." International
Review of Cytology 117 (1989): 171-227.
2. Farquhar, Marilyn G., and George E. Palade. "The Golgi
apparatus: 100 years of progress and controversy."
Trends in Cell Biology 8.1 (1998): 2-10.
Secretory Functions
1. Lippincott-Schwartz, Jennifer, and Hesso Farhan.
"Membrane traffic in the secretory pathway." Cell 112.5
(2003): 507-517.
2. Varki, Ajit, et al. "Essentials of Glycobiology. 3rd
edition." Cold Spring Harbor Laboratory Press, 2015.