AMOXICILLIN

Summary
Amoxicillin is a penicillin derivative used for the treatment of infections caused by gram-
positive bacteria, in particular streptococcal bacteria causing upper respiratory tract
infections.

Brand Names
Amoxil, Augmentin, Clavulin, Moxatag, Omeclamox, Prevpac, Talicia, Voquezna 14 Day
Dualpak 20;500, Voquezna 14 Day Triplepak 20;500;500
Generic Name
Amoxicillin
DrugBank Accession Number
DB01060
Background
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972.6
Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum
concentrations than ampicillin.

Amoxicillin was granted FDA approval on 18 January 1974.12

Indication

Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear,

nose, throat, genitourinary tract, skin, skin structure, and lower respiratory
tract.

Amoxicillin is given with calvulanic acid to treat acute bacterial sinusitis,

community acquired pneumonia, lower respiratory tract infections, acute
bacterial otitis media, skin and skin structure infections, and urinary tract
infections.

Amoxicillin is given with omeprazole in the treatment of Helicobacter pylori (H.

pylori) infection.

Amoxicillin is used in combination with vonoprazan and clarithromycin as co-

packaged triple therapy or in combination with vonoprazan as co-packaged
dual therapy to treat H. pylori infection in adults.
Toxicity

Patients experiencing an overdose may present with hematuria,

oliguria, abdominal pain, acute renal failure, vomiting, diarrhea,
rash, hyperactivity, and drowsiness.

Treat overdose with symptomatic and supportive treatment,

which may include emesis or hemodialysis.
Questions and answers
✓ What is amoxicillin ?
✓ Make sentences into future tense with amoxicillin
✓ What is the toxicity about this medicine?

Link
https://go.drugbank.com/drugs/DB01060
Complete the chart about amoxicillin

Generic Name Brand Name Dose Time Indications

symptoms